SlideShare a Scribd company logo
Traumatic and mechanical 
disorders of musculoskeletal 
system 
อ.นพ.สุวิทยา เธียรประธาน 
สานักวิชาแพทยศาสตร์
Objectives 
• ระบุกายวิภาควิทยาของเอ็นกระดูก เอ็นกล้ามเนื้อ กระดูก และข้อกระดูกใน 
ส่วนต่างๆของร่างกายได้ถูกต้อง 
• อธิบายกลไกพยาธิสรีรวิทยาที่ทาให้เกิดแต่ละอาการบอกเล่า(chief 
complaint) และอาการแสดง(physical examination) ได้ 
อย่างถูกต้อง 
• อธิบายอาการแสดงของกลุ่มการบาดเจ็บของเอ็นกระดูก เอ็นกล้ามเนื้อ 
กระดูก และข้อกระดูกที่พบบ่อยในเวชปฏิบัติได้อย่างถูกต้อง 
• ให้การวินิจฉัยการบาดเจ็บของเอ็นกระดูก เอ็นกล้ามเนื้อ กระดูก และข้อ 
กระดูกได้อย่างถูกต้อง 
• อธิบายผลกระทบของการบาดเจ็บของเอ็นกระดูก เอ็นกล้ามเนื้อ กระดูก และ 
ข้อกระดูกต่อจิตใจและสังคม 
• ให้การวินิจฉัย compartment syndrome ได้อย่างถูกต้อง
Ligament sprains 
• เอ็นกระดูก คือโครงสร้างเนื้อเยื่อหนาแน่นที่แข็งแรง เป็นส่วนประกอบ 
ของข้อกระดูก เป็นส่วนเชื่อมกระดูกแต่ละชิ้นเข้าด้วยกัน 
• มีความยืดหยุ่นได้บางส่วนแต่แข็งแรงกว่าเอ็นกล้ามเนื้อ 
• ประกอบไปด้วย extracellular matrix, Proteoglycan, 
collagen, Fibroblast ฯลฯ
Classification
Ligamentous injuries of the knee
Intra-articular structures 
• ACL 
• PCL 
• Medial meniscus 
• Lateral meniscus
Extra-articular structures 
• MCL 
• LCL 
• Posterolateral corner complex : Biceps 
femoris tendon, Arcuate ligament, 
Fabellofibular ligament, Popliteus tendon, 
Popliteofibular ligament, Posterior oblique 
collateral ligament, Plantaris longus muscle, 
Lateral gastrocnemius muscle(tendon part) 
etc.
Common injuries 
• ACL injury 
• PCL injury 
• MCL injury 
• LCL injury 
• Meniscus injury
Cause of injury 
• Sport injury 
• Motor vehicle injury
Natural history 
• Ligament injury : Knee instability 
• Meniscus injury : pain, range of motion 
• Cartilage injury 
• Osteoarthritis
Physical examination 
• Swelling 
• Point of tenderness 
• Limitation of range of motion 
• Special tests ***
Special tests 
Stability test 
• Anterior drawer test 
• Posterior drawer test 
• Varus stress test 
• Valgus stress test 
• Prone external rotation test 
• Lachman test 
• Lateral pivot shift test
Lachman test
Special tests (cont.) 
Meniscus test 
• McMurray test 
• Apley grind test 
• Squat test
McMurray test
Apley grind test
Investigation or Imaging 
• Plain film X-ray 
• MRI (Magnetic Resonance Imaging)
Treatment 
• Depend on which ligament was injuried 
• Non-operative treatment 
• Operative treatment : Repair, Reconstruction
Ligamentous injuries of the ankle
Key structures 
• ATFL : Anterior Tibiofibular ligament 
• Deltoid ligament 
• Syndesmotic ligament
Mechanisms of injury
Physical examinations 
• Swelling 
• Point of tenderness 
• Inability to bear weight 
• Special test ***
Anterior Drawer Test
Talar Tilt Test
Squeeze test External rotation test
Investigation or Imaging 
• Plain film radiograph : AP ,lateral, mortise 
view 
• For exclude bone fracture 
• Able to exclude ligament sprain grade by 
measuring parameter
Radiographs
Treatment 
• Ankle sprain grade 1 + 2 : Immobilize in slab 
or cast 
• Ankle sprain grade 3 : Surgery  Repair
Ligament healing 
1. Inflammatory phase 
2. Reparative phase 
3. Remodeling phase
Strain 
• ตัวคาศัพท์เดิมหมายถึง ความตึง ความเค้น 
• ตามหลักกลศาสตร์ คานี้ หมายถึง ความยาวที่เปลี่ยนแปลงไปเมื่อถูก 
กระทาด้วยแรงค่าๆหนึ่งต่อหนึ่งหน่วยพื้นที่ 
• แต่ในทางการแพทย์น่าจะหมายถึงกลุ่มอาการที่กล้ามเนื้อหรือเอ็น 
กล้ามเนื้ออักเสบจากการถูกแรงรูปแบบใดๆมากระทา 
• Muscle and Tendon
Anatomy
Tendon 
• เอ็นกล้ามเนื้อ คือ อวัยวะส่วนทเี่ชื่อมต่อกล้ามเนื้อกับปุ่มกระดูก มีหน้าที่ 
ช่วยรวบรวมแรงกระทาจากกล้ามเนื้อ ทาให้การทางานของกล้ามเนื้อมี 
ประสิทธิภาพมากขึ้น 
• มีความแข็งแรงอยู่ระหว่างกระดูกและกล้ามเนื้อ 
• มีส่วนประกอบของ Extracellular matrix, Collagen, 
Proteoglycan, Tenocyte, Tenoblast
Causes 
• Improper use 
• Heavy lifting 
• Over-stretched 
• Occurs in Lower back, Neck, shoulder, Thigh
Treatment 
• Rest 
• Immobilization 
• NSAIDs : Non Steroidal Anti Inflammatory 
Drugs 
• Physiotherapy : Short wave, U/S
Fractures
BONE AND JOINT INJURIES 
• Fracture = Disruptions of bone tissue 
• Osteochondral or intraarticular fractures = 
Visible disruptions of articular cartilage or 
fractures involved both the articular cartilage 
and subchondral bone 
• Chondral fractures = involved only the 
cartilage
Gross anatomy 
• Spine 
• Upper extremity 
• Lower extremity 
• Pelvis
Bone Tissue 
• Its tensile strength nearly equals that of 
cast iron 
• 3 times lighter 
• 10 times more flexible 
• Consists of mesenchymal cells embeded 
within abundant extracellular matrix 
• Constantly changing in response to 
mechanical and hormonal signals
Bone Tissue 
The matrix contains : 
1. Mineral  great strength and stiffness 
in compression and bending 
2. Collagen type 1  strength and 
plasticity 
3. Cytokine , Growth factors
Periosteum 
• Outer layer  more fibrous layer 
• Inner layer  more cellular and vascular 
cambium layer 
• Participates in healing of many types of 
fractures 
• In children , Thicker periosteum than 
Adults
Types of Bone 
Woven bone (immature bone) 
• Embryonic skeleton 
• More rapid rate of 
deposition and resorption 
• Initial fracture repair 
• Irregular pattern of matrix 
fibrils 
• relatively high cell content 
and water concentration 
• 4 times the number of 
osteocytes per unit volume 
• Less stiffness 
• More easily deformed 
Lamellar bone (mature bone) 
• Replaces woven bone 
during growth and 
development 
• Replaces woven bone in 
remodeling phase under 
mechanical load 
• More stiffness 
• Difficultly deformed
Bone formation 
1. Cutting cone 
2. Intramembranous formation 
3. Endochondral bone formation
Cutting cone 
• Primarily a mechanism to remodel bone 
• Osteoclasts at the front 
• Trailing osteoblasts lay down new bone
Intramembranous formation 
• Long bone grows in width 
• Osteoblasts differentiate directly from 
preosteoblasts and lay down seams of 
osteoid 
• Do not involve cartilage anlage
Endochondral bone formation 
• Long bone grows in length 
• The chondrocytes hypertrophy, degenerate 
and calcify 
• Vascular invasion of cartilage occurs followed 
by ossification
Stages of Fracture healing 
• Inflammation 
• Repair 
• Remodeling
Inflammatory phase 
• Require high energy until remodeling 
• Inflammatory mediators released from 
platelets, dead cells 
• Vasodilatation and exudate plasma 
edema in the region 
• Macrophages and Lymphocyte migration 
• The inflammatory response subsides, 
necrotic tissue and exudate are resorbed
Repair phase 
• Fibroblasts and chondrocytes start 
producing a new matrix, the fracture 
callus 
• Follows inflammatory phase rapidly 
• Unstable Vs Stable fracture ???
Repair and Remodeling of 
Unstable Fractures (Secondary 
bone healing 
• Organization of hematoma  first step 
in fracture repair 
• Initiate fracture healing 
• The intact fracture hematoma provides a 
fibrin scaffold that facilitates migration 
of repair cells
• Platelets and cells in hematoma release 
GFs and other proteins  cell 
migration, proliferation, matrix 
synthesis 
• Blood supply, medullary system and 
periosteum are important for fracture 
healing 
• The mesenchymal cells proliferate, 
differentiate, and produce the fracture 
callus consisting of fibrous tissue, 
cartilage, and woven bone
Osteoclast 
• Derived from circulating monocytes in 
the blood and monocytic precursor cells 
from the bone marrow 
• Do not appear to form repair tissue
Osteoblast 
• Develop from the 
undifferentiated 
mesenchymal cells 
that migrate into 
the fracture site 
• Participate in bone 
formation
• Hard (bony) callus 
“The bone formed initially at the 
periphery of the callus by 
intramembranous bone formation” 
• Soft (fibrous and cartilaginous) callus 
“forms in the central regions with low 
oxygen tension and consists primarily of 
cartilage and fibrous tissue” 
• Endochondral ossification 
enlarging the hard callus and increasing 
the stability of the fracture fragments
Callus
• At these stages, the healing is not 
complete 
• The immature fracture callus is weaker 
than normal bone 
• Gaining full strength during remodeling 
phase 
• During final stage of Repair, Remodeling 
of the repair tissue begins with 
replacement of woven bone by lamellar 
bone and resorption of unneeded callus
• By radioisotope studies, the remodeling 
process continues for year after clinical 
and radiographic union 
• Decrease bone density and remains 
changes for years
Repair and Remodeling of Stabilized 
Fractures (Primary Bone Healing) 
The fracture surfaces are rigidly held in 
contact 
Fracture healing can occur without 
grossly visible callus in either cancellous 
or cortical bone 
Called “ Primary bone healing” 
Small bone gaps Vs bone contact??
• Lamellar bone can form directly across 
the fracture line by extension of osteons 
• A cluster of osteoclasts cuts across the 
fracture line, osteoblasts following the 
osteoclasts deposit new bone, and blood 
vessels follow the osteoblasts 
• The new bone matrix, enclosed 
osteocytes, and blood vessels form new 
haversian systems.
Joint tissue (synovial joint) 
• Congruent articulating cartilaginous surfaces 
• Subchondral bone 
• Metaphyseal bone 
• Joint capsule 
• Ligaments 
• Synovial membrane 
• **fibrous tissue meniscus** (labrum)
Articular cartilage 
• Sparsely distributed chondrocytes 
• Surrounded by an elaborate, highly organized 
macromolecular framework filled with water 
• Collagens, Proteoglycans and Non-collagenous 
proteins form the 
macromolecular framework
Physical examination 
• Pain 
• Swelling 
• Tenderness 
• Limitation of Range of motion 
• Neurological status 
• Vascular status
Imaging 
• Plain film X-ray 
• Computerized Tomography
Treatment 
• Non-operative 
• Operative 
Decision making depend on 
• Site of injury, 
• Severity of injury 
• Fracture configuration 
• Surrounding structures injury 
• Other organ system injury 
• Patient’s underlying disease
Non-operative treatments 
• Splint 
• Slab 
• Casting 
• Bracing 
• Traction
Operative treatments 
Internal fixation 
• Dynamic compression plate and screw 
• Locking plate and screw 
• Intramedullary nailing system 
• Wiring 
External fixation 
• External fixator 
• Ilizarov system
Principles of treatment 
• Displacement 
• Intra-articular involvement 
• Soft tissue injury 
• Nerve and Vascular injury 
• Diaphysis of Lower extremity : Nailing
Bone Healing 
• Dynamic compression plate : Primary 
• Locking plate : Secondary 
• Nailing : Secondary 
• Wiring : Primary 
• External fixator : Secondary 
• Ilizarov : Distraction osteogenesis
“Clinical union” 
• Stability of the fracture fragments 
progressively increases because of the 
internal and external callus formation 
• The fracture site becomes stable and 
pain-free
“Radiographic union” 
• Plain radiographs show bone trabeculae 
or cortical bone crossing the fracture site 
• Often occurs later than clinical union
Failure of Fracture Healing
Delay union 
• Fracture line remains clearly visible 
radiographically 
• There is no undue separation of the 
fragments, no cavitation of the surfaces, no 
calcification, and no sclerosis 
• Related to the severity of the injury, poor 
blood supply, the age and nutritional status 
of the patient, or other factors
Nonunion 
• An arrest of the healing process 
• With a large volume of callus called 
“Hypertrophic nonunion” 
• With some callus but less than normal 
“Oligotrophic nonunion” 
• Without callus or less called “Atrophic 
nonunion” 
• With cartilagenous tissue and clear fluid filled in 
cavity called “Pseudarthrosis” 
• “A Fibrous Union”
Hypertrophic 
Non-union
Oligotrophic 
non-union
Atrophic 
Nonunion
Synovial pseudarthrosis
Dislocation 
• Joint dislocation 
• Low velocity  Shoulder, Elbow, wrist, finger 
• High velocity  Hip, Knee, Ankle
Common direction 
• Shoulder : anterior 
• Elbow : posterior 
• Wrist : Lunate volar dislocation 
• Finger : Posterior 
• Hip : posterior 
• Knee : all direction 
• Ankle : all direction
Physical examination 
• Mark swelling 
• Mark deformity 
• Limitation of motion 
• Neurological status 
• Vascular status
Imaging 
• Plain film X-ray
Treatment 
• Emergency closed reduction 
• Under sedation 
• Under General anesthesia 
• Open reduction
Acute compartment syndrome 
• ให้หาอ่านและศึกษาเองเนื่องจากมีอยู่ในโจทย์ POL 
• แนะนาให้อ่าน paper ที่จะให้ใน FB

More Related Content

Viewers also liked

Biochemical identification of bacteria
Biochemical identification of bacteriaBiochemical identification of bacteria
Biochemical identification of bacteria
Bianca Isaguirre
 
Mandibular fracture
Mandibular fractureMandibular fracture
Mandibular fracture
Soyebo Oluseye
 
Identification of bacteria, Bacterial identification, Lab identification of b...
Identification of bacteria, Bacterial identification, Lab identification of b...Identification of bacteria, Bacterial identification, Lab identification of b...
Identification of bacteria, Bacterial identification, Lab identification of b...
Hari, Thoothukudi Govt. Medical College, Thoothukudi
 
Ergonomics in dentistry
Ergonomics in dentistryErgonomics in dentistry
Ergonomics in dentistry
Rakesh Nair
 
14 Principles of HENRI FAYOL project on KFC Class-XII
14 Principles of HENRI FAYOL  project on KFC Class-XII14 Principles of HENRI FAYOL  project on KFC Class-XII
14 Principles of HENRI FAYOL project on KFC Class-XII
Atif Khan
 
Visual Design with Data
Visual Design with DataVisual Design with Data
Visual Design with Data
Seth Familian
 
How to Make Awesome SlideShares: Tips & Tricks
How to Make Awesome SlideShares: Tips & TricksHow to Make Awesome SlideShares: Tips & Tricks
How to Make Awesome SlideShares: Tips & Tricks
SlideShare
 
Getting Started With SlideShare
Getting Started With SlideShareGetting Started With SlideShare
Getting Started With SlideShare
SlideShare
 

Viewers also liked (8)

Biochemical identification of bacteria
Biochemical identification of bacteriaBiochemical identification of bacteria
Biochemical identification of bacteria
 
Mandibular fracture
Mandibular fractureMandibular fracture
Mandibular fracture
 
Identification of bacteria, Bacterial identification, Lab identification of b...
Identification of bacteria, Bacterial identification, Lab identification of b...Identification of bacteria, Bacterial identification, Lab identification of b...
Identification of bacteria, Bacterial identification, Lab identification of b...
 
Ergonomics in dentistry
Ergonomics in dentistryErgonomics in dentistry
Ergonomics in dentistry
 
14 Principles of HENRI FAYOL project on KFC Class-XII
14 Principles of HENRI FAYOL  project on KFC Class-XII14 Principles of HENRI FAYOL  project on KFC Class-XII
14 Principles of HENRI FAYOL project on KFC Class-XII
 
Visual Design with Data
Visual Design with DataVisual Design with Data
Visual Design with Data
 
How to Make Awesome SlideShares: Tips & Tricks
How to Make Awesome SlideShares: Tips & TricksHow to Make Awesome SlideShares: Tips & Tricks
How to Make Awesome SlideShares: Tips & Tricks
 
Getting Started With SlideShare
Getting Started With SlideShareGetting Started With SlideShare
Getting Started With SlideShare
 

Similar to Traumatic and mechanical disorders of musculoskeletal system

Teleconferance (1)
Teleconferance (1)Teleconferance (1)
Teleconferance (1)
Toey Sutisa
 
skeletal system
skeletal systemskeletal system
skeletal system
RungsaritS
 
การบำบัดโรคกล้ามเนื้อ กระดูก และข้อ Tiger balm 03 n0v2013
การบำบัดโรคกล้ามเนื้อ กระดูก และข้อ Tiger balm 03 n0v2013การบำบัดโรคกล้ามเนื้อ กระดูก และข้อ Tiger balm 03 n0v2013
การบำบัดโรคกล้ามเนื้อ กระดูก และข้อ Tiger balm 03 n0v2013
wanghatyai
 
Inflammatory & Infection orthopaedics disease for nursing students 2017
Inflammatory & Infection orthopaedics disease for nursing students 2017Inflammatory & Infection orthopaedics disease for nursing students 2017
Inflammatory & Infection orthopaedics disease for nursing students 2017
Aphisit Aunbusdumberdor
 
Pathological shaft of humerus fx
Pathological shaft of humerus fxPathological shaft of humerus fx
Pathological shaft of humerus fx
Toey Sutisa
 
Non-infectious orthopedic problem for nursing students 2560
Non-infectious orthopedic problem for nursing students 2560Non-infectious orthopedic problem for nursing students 2560
Non-infectious orthopedic problem for nursing students 2560
Aphisit Aunbusdumberdor
 

Similar to Traumatic and mechanical disorders of musculoskeletal system (7)

Teleconferance (1)
Teleconferance (1)Teleconferance (1)
Teleconferance (1)
 
skeletal system
skeletal systemskeletal system
skeletal system
 
การบำบัดโรคกล้ามเนื้อ กระดูก และข้อ Tiger balm 03 n0v2013
การบำบัดโรคกล้ามเนื้อ กระดูก และข้อ Tiger balm 03 n0v2013การบำบัดโรคกล้ามเนื้อ กระดูก และข้อ Tiger balm 03 n0v2013
การบำบัดโรคกล้ามเนื้อ กระดูก และข้อ Tiger balm 03 n0v2013
 
Inflammatory & Infection orthopaedics disease for nursing students 2017
Inflammatory & Infection orthopaedics disease for nursing students 2017Inflammatory & Infection orthopaedics disease for nursing students 2017
Inflammatory & Infection orthopaedics disease for nursing students 2017
 
Pathological shaft of humerus fx
Pathological shaft of humerus fxPathological shaft of humerus fx
Pathological shaft of humerus fx
 
Non-infectious orthopedic problem for nursing students 2560
Non-infectious orthopedic problem for nursing students 2560Non-infectious orthopedic problem for nursing students 2560
Non-infectious orthopedic problem for nursing students 2560
 
12
1212
12
 

Traumatic and mechanical disorders of musculoskeletal system

  • 1. Traumatic and mechanical disorders of musculoskeletal system อ.นพ.สุวิทยา เธียรประธาน สานักวิชาแพทยศาสตร์
  • 2. Objectives • ระบุกายวิภาควิทยาของเอ็นกระดูก เอ็นกล้ามเนื้อ กระดูก และข้อกระดูกใน ส่วนต่างๆของร่างกายได้ถูกต้อง • อธิบายกลไกพยาธิสรีรวิทยาที่ทาให้เกิดแต่ละอาการบอกเล่า(chief complaint) และอาการแสดง(physical examination) ได้ อย่างถูกต้อง • อธิบายอาการแสดงของกลุ่มการบาดเจ็บของเอ็นกระดูก เอ็นกล้ามเนื้อ กระดูก และข้อกระดูกที่พบบ่อยในเวชปฏิบัติได้อย่างถูกต้อง • ให้การวินิจฉัยการบาดเจ็บของเอ็นกระดูก เอ็นกล้ามเนื้อ กระดูก และข้อ กระดูกได้อย่างถูกต้อง • อธิบายผลกระทบของการบาดเจ็บของเอ็นกระดูก เอ็นกล้ามเนื้อ กระดูก และ ข้อกระดูกต่อจิตใจและสังคม • ให้การวินิจฉัย compartment syndrome ได้อย่างถูกต้อง
  • 3.
  • 4. Ligament sprains • เอ็นกระดูก คือโครงสร้างเนื้อเยื่อหนาแน่นที่แข็งแรง เป็นส่วนประกอบ ของข้อกระดูก เป็นส่วนเชื่อมกระดูกแต่ละชิ้นเข้าด้วยกัน • มีความยืดหยุ่นได้บางส่วนแต่แข็งแรงกว่าเอ็นกล้ามเนื้อ • ประกอบไปด้วย extracellular matrix, Proteoglycan, collagen, Fibroblast ฯลฯ
  • 5.
  • 8.
  • 9.
  • 10.
  • 11. Intra-articular structures • ACL • PCL • Medial meniscus • Lateral meniscus
  • 12. Extra-articular structures • MCL • LCL • Posterolateral corner complex : Biceps femoris tendon, Arcuate ligament, Fabellofibular ligament, Popliteus tendon, Popliteofibular ligament, Posterior oblique collateral ligament, Plantaris longus muscle, Lateral gastrocnemius muscle(tendon part) etc.
  • 13.
  • 14. Common injuries • ACL injury • PCL injury • MCL injury • LCL injury • Meniscus injury
  • 15.
  • 16.
  • 17. Cause of injury • Sport injury • Motor vehicle injury
  • 18. Natural history • Ligament injury : Knee instability • Meniscus injury : pain, range of motion • Cartilage injury • Osteoarthritis
  • 19. Physical examination • Swelling • Point of tenderness • Limitation of range of motion • Special tests ***
  • 20. Special tests Stability test • Anterior drawer test • Posterior drawer test • Varus stress test • Valgus stress test • Prone external rotation test • Lachman test • Lateral pivot shift test
  • 21.
  • 22.
  • 23.
  • 24.
  • 25.
  • 27. Special tests (cont.) Meniscus test • McMurray test • Apley grind test • Squat test
  • 30. Investigation or Imaging • Plain film X-ray • MRI (Magnetic Resonance Imaging)
  • 31. Treatment • Depend on which ligament was injuried • Non-operative treatment • Operative treatment : Repair, Reconstruction
  • 33.
  • 34.
  • 35. Key structures • ATFL : Anterior Tibiofibular ligament • Deltoid ligament • Syndesmotic ligament
  • 37.
  • 38. Physical examinations • Swelling • Point of tenderness • Inability to bear weight • Special test ***
  • 41. Squeeze test External rotation test
  • 42. Investigation or Imaging • Plain film radiograph : AP ,lateral, mortise view • For exclude bone fracture • Able to exclude ligament sprain grade by measuring parameter
  • 44.
  • 45.
  • 46.
  • 47. Treatment • Ankle sprain grade 1 + 2 : Immobilize in slab or cast • Ankle sprain grade 3 : Surgery  Repair
  • 48. Ligament healing 1. Inflammatory phase 2. Reparative phase 3. Remodeling phase
  • 49.
  • 50.
  • 51.
  • 52. Strain • ตัวคาศัพท์เดิมหมายถึง ความตึง ความเค้น • ตามหลักกลศาสตร์ คานี้ หมายถึง ความยาวที่เปลี่ยนแปลงไปเมื่อถูก กระทาด้วยแรงค่าๆหนึ่งต่อหนึ่งหน่วยพื้นที่ • แต่ในทางการแพทย์น่าจะหมายถึงกลุ่มอาการที่กล้ามเนื้อหรือเอ็น กล้ามเนื้ออักเสบจากการถูกแรงรูปแบบใดๆมากระทา • Muscle and Tendon
  • 54. Tendon • เอ็นกล้ามเนื้อ คือ อวัยวะส่วนทเี่ชื่อมต่อกล้ามเนื้อกับปุ่มกระดูก มีหน้าที่ ช่วยรวบรวมแรงกระทาจากกล้ามเนื้อ ทาให้การทางานของกล้ามเนื้อมี ประสิทธิภาพมากขึ้น • มีความแข็งแรงอยู่ระหว่างกระดูกและกล้ามเนื้อ • มีส่วนประกอบของ Extracellular matrix, Collagen, Proteoglycan, Tenocyte, Tenoblast
  • 55.
  • 56. Causes • Improper use • Heavy lifting • Over-stretched • Occurs in Lower back, Neck, shoulder, Thigh
  • 57.
  • 58. Treatment • Rest • Immobilization • NSAIDs : Non Steroidal Anti Inflammatory Drugs • Physiotherapy : Short wave, U/S
  • 59.
  • 61. BONE AND JOINT INJURIES • Fracture = Disruptions of bone tissue • Osteochondral or intraarticular fractures = Visible disruptions of articular cartilage or fractures involved both the articular cartilage and subchondral bone • Chondral fractures = involved only the cartilage
  • 62. Gross anatomy • Spine • Upper extremity • Lower extremity • Pelvis
  • 63. Bone Tissue • Its tensile strength nearly equals that of cast iron • 3 times lighter • 10 times more flexible • Consists of mesenchymal cells embeded within abundant extracellular matrix • Constantly changing in response to mechanical and hormonal signals
  • 64.
  • 65. Bone Tissue The matrix contains : 1. Mineral  great strength and stiffness in compression and bending 2. Collagen type 1  strength and plasticity 3. Cytokine , Growth factors
  • 66. Periosteum • Outer layer  more fibrous layer • Inner layer  more cellular and vascular cambium layer • Participates in healing of many types of fractures • In children , Thicker periosteum than Adults
  • 67. Types of Bone Woven bone (immature bone) • Embryonic skeleton • More rapid rate of deposition and resorption • Initial fracture repair • Irregular pattern of matrix fibrils • relatively high cell content and water concentration • 4 times the number of osteocytes per unit volume • Less stiffness • More easily deformed Lamellar bone (mature bone) • Replaces woven bone during growth and development • Replaces woven bone in remodeling phase under mechanical load • More stiffness • Difficultly deformed
  • 68.
  • 69. Bone formation 1. Cutting cone 2. Intramembranous formation 3. Endochondral bone formation
  • 70. Cutting cone • Primarily a mechanism to remodel bone • Osteoclasts at the front • Trailing osteoblasts lay down new bone
  • 71. Intramembranous formation • Long bone grows in width • Osteoblasts differentiate directly from preosteoblasts and lay down seams of osteoid • Do not involve cartilage anlage
  • 72. Endochondral bone formation • Long bone grows in length • The chondrocytes hypertrophy, degenerate and calcify • Vascular invasion of cartilage occurs followed by ossification
  • 73. Stages of Fracture healing • Inflammation • Repair • Remodeling
  • 74. Inflammatory phase • Require high energy until remodeling • Inflammatory mediators released from platelets, dead cells • Vasodilatation and exudate plasma edema in the region • Macrophages and Lymphocyte migration • The inflammatory response subsides, necrotic tissue and exudate are resorbed
  • 75.
  • 76. Repair phase • Fibroblasts and chondrocytes start producing a new matrix, the fracture callus • Follows inflammatory phase rapidly • Unstable Vs Stable fracture ???
  • 77.
  • 78. Repair and Remodeling of Unstable Fractures (Secondary bone healing • Organization of hematoma  first step in fracture repair • Initiate fracture healing • The intact fracture hematoma provides a fibrin scaffold that facilitates migration of repair cells
  • 79. • Platelets and cells in hematoma release GFs and other proteins  cell migration, proliferation, matrix synthesis • Blood supply, medullary system and periosteum are important for fracture healing • The mesenchymal cells proliferate, differentiate, and produce the fracture callus consisting of fibrous tissue, cartilage, and woven bone
  • 80. Osteoclast • Derived from circulating monocytes in the blood and monocytic precursor cells from the bone marrow • Do not appear to form repair tissue
  • 81. Osteoblast • Develop from the undifferentiated mesenchymal cells that migrate into the fracture site • Participate in bone formation
  • 82. • Hard (bony) callus “The bone formed initially at the periphery of the callus by intramembranous bone formation” • Soft (fibrous and cartilaginous) callus “forms in the central regions with low oxygen tension and consists primarily of cartilage and fibrous tissue” • Endochondral ossification enlarging the hard callus and increasing the stability of the fracture fragments
  • 84.
  • 85.
  • 86.
  • 87. • At these stages, the healing is not complete • The immature fracture callus is weaker than normal bone • Gaining full strength during remodeling phase • During final stage of Repair, Remodeling of the repair tissue begins with replacement of woven bone by lamellar bone and resorption of unneeded callus
  • 88. • By radioisotope studies, the remodeling process continues for year after clinical and radiographic union • Decrease bone density and remains changes for years
  • 89.
  • 90. Repair and Remodeling of Stabilized Fractures (Primary Bone Healing) The fracture surfaces are rigidly held in contact Fracture healing can occur without grossly visible callus in either cancellous or cortical bone Called “ Primary bone healing” Small bone gaps Vs bone contact??
  • 91. • Lamellar bone can form directly across the fracture line by extension of osteons • A cluster of osteoclasts cuts across the fracture line, osteoblasts following the osteoclasts deposit new bone, and blood vessels follow the osteoblasts • The new bone matrix, enclosed osteocytes, and blood vessels form new haversian systems.
  • 92.
  • 93.
  • 94.
  • 95.
  • 96.
  • 97.
  • 98.
  • 99.
  • 100.
  • 101.
  • 102. Joint tissue (synovial joint) • Congruent articulating cartilaginous surfaces • Subchondral bone • Metaphyseal bone • Joint capsule • Ligaments • Synovial membrane • **fibrous tissue meniscus** (labrum)
  • 103.
  • 104. Articular cartilage • Sparsely distributed chondrocytes • Surrounded by an elaborate, highly organized macromolecular framework filled with water • Collagens, Proteoglycans and Non-collagenous proteins form the macromolecular framework
  • 105.
  • 106.
  • 107. Physical examination • Pain • Swelling • Tenderness • Limitation of Range of motion • Neurological status • Vascular status
  • 108. Imaging • Plain film X-ray • Computerized Tomography
  • 109.
  • 110.
  • 111. Treatment • Non-operative • Operative Decision making depend on • Site of injury, • Severity of injury • Fracture configuration • Surrounding structures injury • Other organ system injury • Patient’s underlying disease
  • 112. Non-operative treatments • Splint • Slab • Casting • Bracing • Traction
  • 113.
  • 114.
  • 115.
  • 116. Operative treatments Internal fixation • Dynamic compression plate and screw • Locking plate and screw • Intramedullary nailing system • Wiring External fixation • External fixator • Ilizarov system
  • 117.
  • 118.
  • 119.
  • 120. Principles of treatment • Displacement • Intra-articular involvement • Soft tissue injury • Nerve and Vascular injury • Diaphysis of Lower extremity : Nailing
  • 121. Bone Healing • Dynamic compression plate : Primary • Locking plate : Secondary • Nailing : Secondary • Wiring : Primary • External fixator : Secondary • Ilizarov : Distraction osteogenesis
  • 122. “Clinical union” • Stability of the fracture fragments progressively increases because of the internal and external callus formation • The fracture site becomes stable and pain-free
  • 123. “Radiographic union” • Plain radiographs show bone trabeculae or cortical bone crossing the fracture site • Often occurs later than clinical union
  • 124.
  • 126. Delay union • Fracture line remains clearly visible radiographically • There is no undue separation of the fragments, no cavitation of the surfaces, no calcification, and no sclerosis • Related to the severity of the injury, poor blood supply, the age and nutritional status of the patient, or other factors
  • 127. Nonunion • An arrest of the healing process • With a large volume of callus called “Hypertrophic nonunion” • With some callus but less than normal “Oligotrophic nonunion” • Without callus or less called “Atrophic nonunion” • With cartilagenous tissue and clear fluid filled in cavity called “Pseudarthrosis” • “A Fibrous Union”
  • 132.
  • 133. Dislocation • Joint dislocation • Low velocity  Shoulder, Elbow, wrist, finger • High velocity  Hip, Knee, Ankle
  • 134. Common direction • Shoulder : anterior • Elbow : posterior • Wrist : Lunate volar dislocation • Finger : Posterior • Hip : posterior • Knee : all direction • Ankle : all direction
  • 135.
  • 136.
  • 137.
  • 138.
  • 139.
  • 140.
  • 141.
  • 142. Physical examination • Mark swelling • Mark deformity • Limitation of motion • Neurological status • Vascular status
  • 143. Imaging • Plain film X-ray
  • 144. Treatment • Emergency closed reduction • Under sedation • Under General anesthesia • Open reduction
  • 145.
  • 146. Acute compartment syndrome • ให้หาอ่านและศึกษาเองเนื่องจากมีอยู่ในโจทย์ POL • แนะนาให้อ่าน paper ที่จะให้ใน FB