Rakesh Jhunjhunwara discusses that trading goes against human nature as humans are motivated by greed for profits and fear of losses. To be successful, one must balance these feelings and know when to cut their losses by selling investments that have declined in price. This requires learning from losses rather than just gains. He also emphasizes the importance of making investment decisions based on market prices and trends, not personal opinions. Finally, he outlines some of his key principles for long-term investing success, including maintaining an optimistic outlook, focusing on value, and being willing to sell at a profit regardless of personal views on a company's prospects.