This document discusses topological string theory and Gromov-Witten invariants. It begins by introducing supersymmetric sigma models on Kähler manifolds with N=2 supersymmetry. These lead to a topological twist known as the A-model, which is independent of the target space metric. Gromov-Witten invariants count rational curves in an algebraic variety X and are unchanged by complex structure deformations of X, making them a manifestation of the A-model's independence of complex structure. The Gromov-Witten invariants are also directly related to Donaldson-Thomas invariants.
This presentation gives some details about graph representation through touching domains. It is also known as kissing disk representation or circle packing. I tried to prove that Koebe's Theorem holds by using Brouwer Fixed-Point Theorem.
This presentation gives some details about graph representation through touching domains. It is also known as kissing disk representation or circle packing. I tried to prove that Koebe's Theorem holds by using Brouwer Fixed-Point Theorem.
Operator’s Differential geometry with Riemannian Manifoldsinventionjournals
In this paper some fundamental theorems , operators differential geometry – with operator Riemannian geometry to pervious of differentiable manifolds which are used in an essential way in basic concepts of Spectrum of Discrete , bounded Riemannian geometry, we study the defections, examples of the problem of differentially projection mapping parameterization system on dimensional manifolds .
OBC | String theory and quests for unification of fundamental forces of natureOut of The Box Seminar
Mirjam Cvetič, University of Pennsylvania, Philadelphia, USA
String theory and quests for unification of fundamental forces of nature
http://obc2012.outofthebox.si/
Within the framework of the general theory of relativity (GR) the modeling of the central symmetrical
gravitational field is considered. The mapping of the geodesic motion of the Lemetr and Tolman basis on
their motion in the Minkowski space on the world lines is determined. The expression for the field intensity
and energy where these bases move is obtained. The advantage coordinate system is found, the coordinates
and the time of the system coincide with the Galilean coordinates and the time in the Minkowski space.
A. JBILOU, Convexity of the Set of k-Admissible Functions on a Compact Kähler Manifold (2014), International Journal of Innovation and Scientific Research, vol. 4, no. 1, pp. 42–46.
Note on Sidharth's Unification of Electromagnetism and Gravitationinventionjournals
In this note, it is shown that the Sidharth's Unification of Electromagnetism and Gravitation is close to the Einstein Tetrad Field and far of Einstein–Cartan–Evans theory. Mathematically in the sector Gravitation-Electromagnetism, Sidharth approach through non commutativity, where there is a minimum space time length, allows to link the vector magnetic potential with quantum mechanics and unify electromagnetism and gravitation under self dual configuration of electromagnetic fields.
All of material inside is un-licence, kindly use it for educational only but please do not to commercialize it.
Based on 'ilman nafi'an, hopefully this file beneficially for you.
Thank you.
M. Visinescu: Hidden Symmetries of the Five-dimensional Sasaki - Einstein SpacesSEENET-MTP
Balkan Workshop BW2013
Beyond the Standard Models
25 – 29 April, 2013, Vrnjačka Banja, Serbia
M. Visinescu: Hidden Symmetries of the Five-dimensional Sasaki - Einstein Spaces
This is a journal concise version (without diagrams and figures) of the preprint arXiv:1308.4060.
Abstract: Polyadic systems and their representations are reviewed and a classification of general polyadic systems is presented. A new multiplace generalization of associativity preserving homomorphisms, a 'heteromorphism' which connects polyadic systems having unequal arities, is introduced via an explicit formula, together with related definitions for multiplace representations and multiactions. Concrete examples of matrix representations for some ternary groups are then reviewed. Ternary algebras and Hopf algebras are defined, and their properties are studied. At the end some ternary generalizations of quantum groups and the Yang-Baxter equation are presented.
Operator’s Differential geometry with Riemannian Manifoldsinventionjournals
In this paper some fundamental theorems , operators differential geometry – with operator Riemannian geometry to pervious of differentiable manifolds which are used in an essential way in basic concepts of Spectrum of Discrete , bounded Riemannian geometry, we study the defections, examples of the problem of differentially projection mapping parameterization system on dimensional manifolds .
OBC | String theory and quests for unification of fundamental forces of natureOut of The Box Seminar
Mirjam Cvetič, University of Pennsylvania, Philadelphia, USA
String theory and quests for unification of fundamental forces of nature
http://obc2012.outofthebox.si/
Within the framework of the general theory of relativity (GR) the modeling of the central symmetrical
gravitational field is considered. The mapping of the geodesic motion of the Lemetr and Tolman basis on
their motion in the Minkowski space on the world lines is determined. The expression for the field intensity
and energy where these bases move is obtained. The advantage coordinate system is found, the coordinates
and the time of the system coincide with the Galilean coordinates and the time in the Minkowski space.
A. JBILOU, Convexity of the Set of k-Admissible Functions on a Compact Kähler Manifold (2014), International Journal of Innovation and Scientific Research, vol. 4, no. 1, pp. 42–46.
Note on Sidharth's Unification of Electromagnetism and Gravitationinventionjournals
In this note, it is shown that the Sidharth's Unification of Electromagnetism and Gravitation is close to the Einstein Tetrad Field and far of Einstein–Cartan–Evans theory. Mathematically in the sector Gravitation-Electromagnetism, Sidharth approach through non commutativity, where there is a minimum space time length, allows to link the vector magnetic potential with quantum mechanics and unify electromagnetism and gravitation under self dual configuration of electromagnetic fields.
All of material inside is un-licence, kindly use it for educational only but please do not to commercialize it.
Based on 'ilman nafi'an, hopefully this file beneficially for you.
Thank you.
M. Visinescu: Hidden Symmetries of the Five-dimensional Sasaki - Einstein SpacesSEENET-MTP
Balkan Workshop BW2013
Beyond the Standard Models
25 – 29 April, 2013, Vrnjačka Banja, Serbia
M. Visinescu: Hidden Symmetries of the Five-dimensional Sasaki - Einstein Spaces
This is a journal concise version (without diagrams and figures) of the preprint arXiv:1308.4060.
Abstract: Polyadic systems and their representations are reviewed and a classification of general polyadic systems is presented. A new multiplace generalization of associativity preserving homomorphisms, a 'heteromorphism' which connects polyadic systems having unequal arities, is introduced via an explicit formula, together with related definitions for multiplace representations and multiactions. Concrete examples of matrix representations for some ternary groups are then reviewed. Ternary algebras and Hopf algebras are defined, and their properties are studied. At the end some ternary generalizations of quantum groups and the Yang-Baxter equation are presented.
We use stochastic methods to present mathematically correct representation of the wave function. Informal construction was developed by R. Feynman. This approach were introduced first by H. Doss Sur une Resolution Stochastique de l'Equation de Schrödinger à Coefficients Analytiques. Communications in Mathematical Physics
October 1980, Volume 73, Issue 3, pp 247–264.
Primary intention is to discuss formal stochastic representation of the Schrodinger equation solution with its applications to the theory of demolition quantum measurements.
I will appreciate your comments.
Multi-source connectivity as the driver of solar wind variability in the heli...Sérgio Sacani
The ambient solar wind that flls the heliosphere originates from multiple
sources in the solar corona and is highly structured. It is often described
as high-speed, relatively homogeneous, plasma streams from coronal
holes and slow-speed, highly variable, streams whose source regions are
under debate. A key goal of ESA/NASA’s Solar Orbiter mission is to identify
solar wind sources and understand what drives the complexity seen in the
heliosphere. By combining magnetic feld modelling and spectroscopic
techniques with high-resolution observations and measurements, we show
that the solar wind variability detected in situ by Solar Orbiter in March
2022 is driven by spatio-temporal changes in the magnetic connectivity to
multiple sources in the solar atmosphere. The magnetic feld footpoints
connected to the spacecraft moved from the boundaries of a coronal hole
to one active region (12961) and then across to another region (12957). This
is refected in the in situ measurements, which show the transition from fast
to highly Alfvénic then to slow solar wind that is disrupted by the arrival of
a coronal mass ejection. Our results describe solar wind variability at 0.5 au
but are applicable to near-Earth observatories.
This pdf is about the Schizophrenia.
For more details visit on YouTube; @SELF-EXPLANATORY;
https://www.youtube.com/channel/UCAiarMZDNhe1A3Rnpr_WkzA/videos
Thanks...!
THE IMPORTANCE OF MARTIAN ATMOSPHERE SAMPLE RETURN.Sérgio Sacani
The return of a sample of near-surface atmosphere from Mars would facilitate answers to several first-order science questions surrounding the formation and evolution of the planet. One of the important aspects of terrestrial planet formation in general is the role that primary atmospheres played in influencing the chemistry and structure of the planets and their antecedents. Studies of the martian atmosphere can be used to investigate the role of a primary atmosphere in its history. Atmosphere samples would also inform our understanding of the near-surface chemistry of the planet, and ultimately the prospects for life. High-precision isotopic analyses of constituent gases are needed to address these questions, requiring that the analyses are made on returned samples rather than in situ.
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
What is greenhouse gasses and how many gasses are there to affect the Earth.moosaasad1975
What are greenhouse gasses how they affect the earth and its environment what is the future of the environment and earth how the weather and the climate effects.
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
2. Topological
Imran Parvez Khan
Department of Physics
Comsats Institute of Information Technology,
Islamabad.
NUST Conference on Mathematical Sciences, CAMP, 2011
Theory
3. • The Basic Argument
String theory is a physics
theory that the universe is
composed of vibrating
filaments of energy, expressed
in precise mathematical
language. These strings of
energy represent the most
fundamental aspect of nature.
4. Supersymmetry
Nature of space-time at Planck scale (10-34 m) is
non-commutative because there are no points.
The goal is to construct a geometry that is
non-commutative but has the Riemann-Einstein
geometry as a limit.
Salam and Strathdee among others suggested
that the classical manifold, should be replaced
by a manifold ℳ, such that it admits additional
set of anti-commuting (Grassman) coordinates.
5. Supergeometry
On our supermanifold ℳ, the local coordinates are given
by
x1, x2,..., xp, θ1, θ2,..., θq.
where the xi are the usual commuting coordinates and θj
are the grassmann coordinates, s.t.,
θj θk + θk θj = 0.
Their nilpotency facilitates us to develop the
cohomological/topological field theory.
The local behavior of differential functions on ℳ is
reflected by a ‘sheaf’. The sections of this sheaf are
referred to as ‘superfields’.
6. BUNDLE
Fibres Total Space Base Space
vector spaces
(e.g TM)
manifold
bundle itself
Section: A vector field is a section of its tangent bundle.
(Co)Homology Class: The (co)homology class measures the extent
to which the bundle is “twisted” - particularly, whether it
possesses sections or not.
7. N=2 supersymmetric sigma Model
Consider a map Φ : Σ → X, where Σ is the
worldsheet, X, called the target space is
interpreted as the physical space-time.
The action for such theory is:
where ψ’s are left moving fermions and λ’s are
right moving fermions, gμν is the metric on the
target manifold and Rµνρσ is its Riemann tensor.
8. N=2 supersymmetric sigma Model
Kähler metric
complex structure ?
(shown in [13])
Complex Manifold: If we demand that the
transition functions φj o φi
-1 satisfy the
Cauchy-Riemann equations, then the analytic
properties of a function f can be studied using its
coordinate representation f o φi
-1 with assurance
that the conclusions drawn are patch independent.
Ricci flat i.e., Rij = 0.
9.
10. Topological String Theory
The A Model of Topological String Theory:
N=2 means we have two complex supercharges
Q- and Q+.
We will connect them to cohomology because cohomology
groups are finite-dimensional.
Dolbeault cohomology ∂ and ∂ .
QA = Q- + Q+ can be identified with the deRham
operator d = ∂ + ∂, because d2 = 0 = Q2.
This procedure leads to a “topological twist”.
The A-Model is metric independent.
Edward Witten shared the 1990 Fields Medal for
his pioneering work in cohomological field theory.
11. Gromov-Witten invariants
Given an alegebraic variety X, we fix a
homology class β=H(X) and cycles
Z1=G(Z0), Z2=G(Z1),...,Z0 = G(Zn-1) on X for
a map G. Then we consider the
following set of curves:
C⊂X of genus g, homology class β, such
that C∩Zi ≠∅ for all i=0,...,n.
12. Gromov-Witten invariants
Let αi ∈ H*(X) be the cohomology class
dual to the cycle Zi, and Mg,n be
Deligne-Mumford moduli space, then
⟨Ig,n,b⟩(α1, α2,..., αn) =∫Mg,n Ig,n,b (α1, α2,..., αn)
is the Gromov Witten invariant which
counts the number of rational curves C.
13. Conclusion
The Gromov-Witten invariants are by design to
be unchanged by deformations of the complex
structure of X.
Thus they are a complete manifestation of the
A-Model’s independence of the complex
structure of the moduli space.
Gromov-Witten invariants are directly related to
another important invariant called Donaldson-
Thomson invariant.
16. References
[13] Zumino, B. Phys. Lett. B87 (1979) 203.
[14] Klemm, A. Notes on Introduction to Topological String Theory (2003)
[15] Hori, et al. “Mirror Symmetry”, AMS CMI (2003)
[16] Cox and Katz, “Mirror Symmetry and Algebraic Geometry” AMS (1999)