Calculate the costs of nicotine addiction. Financial is just one measure. This slide show asks you some hard hitting questions. If you need some help to break through your denial, ask yourself these question.
Wedding is one of the most important and special day for ever couple. Although, considered a significantly important day for the bride, it is as special for the groom as for the bride. A surprise gift from the bride to the groom will be a great way to start a new life. Here are top personalized wedding gifts every groom will love to have.
Undergarments changed after 1940, with bras and girdles becoming separate pieces. Wire was added to bras and nylon stockings returned to stores after World War II. When planning bulk purchases of women's fashion clothing, it is important to thoroughly research the most reputable wholesale suppliers or drop shippers to ensure the best investment. Clothing can create illusions about one's physique, allowing people to look thinner or potentially heavier, so wearing the right clothes in the proper fashion is a proven solution for weight management issues. Makeup, like eye makeup, can alter one's face for fashion but should be applied carefully to avoid scaring others.
Aldi is offering a $250 gift card to customers who click on a link to learn more. Customers who love Aldi can save even more with a $250 gift card from the store. Clicking the link provided will give users more information about how to get a $250 Aldi gift card.
This document shares music memes with inspiring song lyrics to make people smile and hum. It hopes the reader enjoyed the slideshare and now has a good song in their head. It also advertises the Serenity Vista Recovery Retreat in Panama, a unique facility that helps people address blocks to living a drug and behavior-free life.
This document provides information about the harms of tobacco and nicotine. It notes that tobacco is the only legal product that is deadly when used as intended. Nicotine is highly addictive and tobacco contains over 4,000 toxic chemicals, including 50 known carcinogens. Smoking affects every part of the body and can cause numerous health issues like cancer, heart disease, stroke, and more. Secondhand smoke is also dangerous and causes both short and long term health effects. The document offers tips for quitting smoking.
Tobacco market research paper Questionnaire Hagi Sahib
This document appears to be a survey about smoking habits. It collects information such as the respondent's name, occupation, age, education level, chief wage earner's occupation, brand of cigarettes smoked, smoking frequency, age started smoking, and opinions on warnings and future smoking. The survey contains 13 multiple choice questions on topics like favorite and past brands smoked, reasons for brand selection, smoking history, acquisition of cigarettes, influences to start smoking, and views on smoking risks and quitting.
The document discusses several points to consider when determining if electronic cigarettes are right for someone trying to quit smoking. It notes that electronic cigarettes may not be helpful if the goal is to be completely rid of smoking and anything related to it. It stresses the importance of being clear upfront about one's goals in using electronic cigarettes, whether it is to fully switch from cigarettes or use them as a bridge to quitting altogether. It also advises that one should have realistic expectations of electronic cigarettes seeing them as a tool rather than a magical solution to problems from smoking.
Wedding is one of the most important and special day for ever couple. Although, considered a significantly important day for the bride, it is as special for the groom as for the bride. A surprise gift from the bride to the groom will be a great way to start a new life. Here are top personalized wedding gifts every groom will love to have.
Undergarments changed after 1940, with bras and girdles becoming separate pieces. Wire was added to bras and nylon stockings returned to stores after World War II. When planning bulk purchases of women's fashion clothing, it is important to thoroughly research the most reputable wholesale suppliers or drop shippers to ensure the best investment. Clothing can create illusions about one's physique, allowing people to look thinner or potentially heavier, so wearing the right clothes in the proper fashion is a proven solution for weight management issues. Makeup, like eye makeup, can alter one's face for fashion but should be applied carefully to avoid scaring others.
Aldi is offering a $250 gift card to customers who click on a link to learn more. Customers who love Aldi can save even more with a $250 gift card from the store. Clicking the link provided will give users more information about how to get a $250 Aldi gift card.
This document shares music memes with inspiring song lyrics to make people smile and hum. It hopes the reader enjoyed the slideshare and now has a good song in their head. It also advertises the Serenity Vista Recovery Retreat in Panama, a unique facility that helps people address blocks to living a drug and behavior-free life.
This document provides information about the harms of tobacco and nicotine. It notes that tobacco is the only legal product that is deadly when used as intended. Nicotine is highly addictive and tobacco contains over 4,000 toxic chemicals, including 50 known carcinogens. Smoking affects every part of the body and can cause numerous health issues like cancer, heart disease, stroke, and more. Secondhand smoke is also dangerous and causes both short and long term health effects. The document offers tips for quitting smoking.
Tobacco market research paper Questionnaire Hagi Sahib
This document appears to be a survey about smoking habits. It collects information such as the respondent's name, occupation, age, education level, chief wage earner's occupation, brand of cigarettes smoked, smoking frequency, age started smoking, and opinions on warnings and future smoking. The survey contains 13 multiple choice questions on topics like favorite and past brands smoked, reasons for brand selection, smoking history, acquisition of cigarettes, influences to start smoking, and views on smoking risks and quitting.
The document discusses several points to consider when determining if electronic cigarettes are right for someone trying to quit smoking. It notes that electronic cigarettes may not be helpful if the goal is to be completely rid of smoking and anything related to it. It stresses the importance of being clear upfront about one's goals in using electronic cigarettes, whether it is to fully switch from cigarettes or use them as a bridge to quitting altogether. It also advises that one should have realistic expectations of electronic cigarettes seeing them as a tool rather than a magical solution to problems from smoking.
UK ecig store the one kit that fits your need in the best manner is available for all those who are keen to shift to a better way of smoking. Smokers will see various other benefits that they will not find otherwise.
The document provides information about ASE certification for automotive technicians. It explains that ASE certification means Automotive Service Excellence certification. To become ASE certified, technicians must pass tests in various automotive systems and repairs areas, such as brakes, engines, transmissions, etc. Becoming an ASE Master Technician requires passing all tests. The article notes the shop has three ASE Master Technicians.
This document provides an analysis and business plan for ReBottled, a company that upcycles glass bottles into drinking glasses. It includes:
1. Market research findings on customer perceptions of recycling and willingness to pay for upcycled products. The average customer is willing to pay €10.31 for a glass.
2. Details on two target customer personas - Vincent and Mia.
3. A SWOT analysis identifying strengths like environmental benefits but also weaknesses like distribution challenges.
4. Recommendations on branding, pricing, financing, and communication strategies to engage customers and promote the social mission.
5. Innovation ideas like creating wine lists, double glasses from single bottles, and ash
The document provides 15 ways for people to reduce spending and increase savings, including creating a spending plan, tracking expenses, paying yourself first by automatically saving a portion of your paycheck, reducing spending on services like cable and phone bills, carrying cash instead of credit cards, saving on food costs through meal planning and couponing, eating out less, saving spare change, reducing energy costs, making coffee at home, paying bills on time to avoid fees, saving on transportation costs through car maintenance and public transit, bringing lunch instead of buying, enjoying free entertainment, saving on gifts and social activities, and reducing insurance and clothing costs through comparison shopping and purchases at discount stores.
An electronic cigarette is a battery-powered device that provides nicotine without smoke. It resembles a traditional cigarette but produces a vapor instead of smoke. Electronic cigarettes allow smokers to control their nicotine intake and eliminate secondhand smoke risks while saving money compared to traditional cigarettes. They can be used anywhere as they do not produce smoke.
This document provides information to help motivate people to quit smoking and offers resources to assist with quitting. It outlines several health benefits of quitting such as improved dental health, appearance, reduced cancer and heart disease risk. It also notes social benefits like being a good role model, protecting loved ones, and living longer. The document recommends free telephone counseling services and websites with calculators, step-by-step guides and support groups. Finally, it offers tips for quitting such as avoiding tobacco products and staying busy, as well as approaches like going cold turkey or gradually tapering use.
10 quick easy tips for everyday life to help you and your family live greener, healthier and save money too. Living a more sustainable lifestyle ensures a better future for our family and our world.
Denettes International Alliance PresentationDenette
Hudson Baylor is a progressive recycling company that helps divert trash from landfills while generating revenue for its customers. It is building an education center in Arizona to teach about sustainability. Recycling rates are low in Arizona due to lack of mandates and convenience. It is more cost effective for private companies to send materials to landfills than to recycle. Bottle bills are effective at increasing recycling rates over 75% by shifting responsibility to producers and consumers.
This document provides the top 5 reasons why a check engine light may come on:
1. An oxygen sensor needs replacing, which can cause other issues if ignored.
2. A loose or faulty gas cap can lower gas mileage and increase emissions.
3. A failing catalytic converter may need to be replaced, which should be prevented through regular maintenance.
4. A mass airflow sensor may need replacing if not maintained through yearly air filter changes.
5. Spark plugs and wires wear over time and should be replaced according to the maintenance schedule.
The key issue is replacing a catalytic converter, as it should not fail with proper regular maintenance. It is important to get any check engine light
The document outlines 9 steps to quit smoking:
1. Ask yourself why you want to stop smoking and write the reasons down.
2. Change your schedule to avoid smoking triggers and use alternatives like gum when cravings hit.
3. Post "no smoking" signs and reminders to reinforce your commitment to quitting.
4. Prepare for cravings by having distractions like water and snacks available.
The document discusses vapor cigarettes, also known as e-cigarettes. It outlines the benefits of vapor cigarettes over traditional cigarettes, such as being healthier, less expensive, and not producing odor or stains. It then describes how vapor cigarettes work using a battery-powered heating element to create a vapor from water in cartridges that can contain nicotine in various flavors. Finally, it provides tips on how to get started with vapor cigarettes, including reading reviews, finding the right brand, and learning proper usage.
This document is from an electronic cigarette retailer called Juicy Cigs. It introduces electronic cigarettes as a cheaper and healthier alternative to traditional cigarettes, with over 70 flavors of e-liquid available. It highlights that customers can save up to 80% compared to the cost of regular cigarettes. The site allows customers to browse different e-cigarette kits and accessories, read reviews from other customers, and learn more about electronic cigarettes.
This document provides summaries of articles on motoring, marine, and aviation topics relevant to the Hibiscus Coast region of New Zealand. It discusses driving tips for the summer months, a comparison of mineral fuels versus biofuel blends, and challenges around keeping Auckland moving in terms of transportation infrastructure and funding.
This document is a homepage for an electronic cigarette retailer called Juicy Cigs. It introduces electronic cigarettes as a cheaper and healthier alternative to traditional cigarettes, with over 70 flavors available. It highlights starter kits and individual products available at a range of prices. Customers can read reviews and find help and information about ordering and the company's policies.
The document discusses the dangers of smoking and provides tips to quit smoking. It notes that World No Tobacco Day is observed annually on May 31st to spread awareness of the health risks of tobacco, which contains over 4,000 chemicals, including 51 carcinogens. Common chemicals in cigarettes include carbon monoxide, nicotine, tar, arsenic, and cyanide. Smoking is linked to 22% of male deaths and 11% of female deaths. The document offers advice to help quit smoking such as using nicotine replacements, keeping busy, and avoiding others who smoke.
The document discusses various strategies for saving money as a consumer. It suggests making lists before shopping, buying generic brands instead of name brands, using coupons, and shopping at discount stores to save on groceries. Driving a fuel-efficient car, checking gas prices, and maintaining reasonable home temperatures can also save money on transportation and utility costs. With careful planning and consideration of long-term savings, consumers can accumulate significant savings over time.
This document discusses exporting blu e-cigarettes to Prague, Czech Republic. It begins with an introduction and background on blu e-cigs. Next, it provides a situation analysis of smoking rates and attitudes in the Czech Republic. It then estimates the target market size in Prague and provides a SWOT analysis. The document continues with sections on competition, product description, financial objectives, target markets, positioning, strategies, marketing mix, organizational structure, and conclusions. The overall aim is to analyze the viability and strategy for introducing blu e-cigs in the Czech market.
Ethical Treatment Centers have been pushed aside by the dearth of unethical and shady operations in California and Florida. So, how to find the right place for your or a loved one?
We are so happy to be sober. These happy fish by http://bobschmitz.com express that joyousness. If you want some joy, consider rehab in Paradise, Serenity Vista Retreat in Panama. A different kind of addiction facility. Holistic, 12 Step, Discreet, find happiness.
More Related Content
Similar to What Has Tobacco Cost You? Enough Already?
UK ecig store the one kit that fits your need in the best manner is available for all those who are keen to shift to a better way of smoking. Smokers will see various other benefits that they will not find otherwise.
The document provides information about ASE certification for automotive technicians. It explains that ASE certification means Automotive Service Excellence certification. To become ASE certified, technicians must pass tests in various automotive systems and repairs areas, such as brakes, engines, transmissions, etc. Becoming an ASE Master Technician requires passing all tests. The article notes the shop has three ASE Master Technicians.
This document provides an analysis and business plan for ReBottled, a company that upcycles glass bottles into drinking glasses. It includes:
1. Market research findings on customer perceptions of recycling and willingness to pay for upcycled products. The average customer is willing to pay €10.31 for a glass.
2. Details on two target customer personas - Vincent and Mia.
3. A SWOT analysis identifying strengths like environmental benefits but also weaknesses like distribution challenges.
4. Recommendations on branding, pricing, financing, and communication strategies to engage customers and promote the social mission.
5. Innovation ideas like creating wine lists, double glasses from single bottles, and ash
The document provides 15 ways for people to reduce spending and increase savings, including creating a spending plan, tracking expenses, paying yourself first by automatically saving a portion of your paycheck, reducing spending on services like cable and phone bills, carrying cash instead of credit cards, saving on food costs through meal planning and couponing, eating out less, saving spare change, reducing energy costs, making coffee at home, paying bills on time to avoid fees, saving on transportation costs through car maintenance and public transit, bringing lunch instead of buying, enjoying free entertainment, saving on gifts and social activities, and reducing insurance and clothing costs through comparison shopping and purchases at discount stores.
An electronic cigarette is a battery-powered device that provides nicotine without smoke. It resembles a traditional cigarette but produces a vapor instead of smoke. Electronic cigarettes allow smokers to control their nicotine intake and eliminate secondhand smoke risks while saving money compared to traditional cigarettes. They can be used anywhere as they do not produce smoke.
This document provides information to help motivate people to quit smoking and offers resources to assist with quitting. It outlines several health benefits of quitting such as improved dental health, appearance, reduced cancer and heart disease risk. It also notes social benefits like being a good role model, protecting loved ones, and living longer. The document recommends free telephone counseling services and websites with calculators, step-by-step guides and support groups. Finally, it offers tips for quitting such as avoiding tobacco products and staying busy, as well as approaches like going cold turkey or gradually tapering use.
10 quick easy tips for everyday life to help you and your family live greener, healthier and save money too. Living a more sustainable lifestyle ensures a better future for our family and our world.
Denettes International Alliance PresentationDenette
Hudson Baylor is a progressive recycling company that helps divert trash from landfills while generating revenue for its customers. It is building an education center in Arizona to teach about sustainability. Recycling rates are low in Arizona due to lack of mandates and convenience. It is more cost effective for private companies to send materials to landfills than to recycle. Bottle bills are effective at increasing recycling rates over 75% by shifting responsibility to producers and consumers.
This document provides the top 5 reasons why a check engine light may come on:
1. An oxygen sensor needs replacing, which can cause other issues if ignored.
2. A loose or faulty gas cap can lower gas mileage and increase emissions.
3. A failing catalytic converter may need to be replaced, which should be prevented through regular maintenance.
4. A mass airflow sensor may need replacing if not maintained through yearly air filter changes.
5. Spark plugs and wires wear over time and should be replaced according to the maintenance schedule.
The key issue is replacing a catalytic converter, as it should not fail with proper regular maintenance. It is important to get any check engine light
The document outlines 9 steps to quit smoking:
1. Ask yourself why you want to stop smoking and write the reasons down.
2. Change your schedule to avoid smoking triggers and use alternatives like gum when cravings hit.
3. Post "no smoking" signs and reminders to reinforce your commitment to quitting.
4. Prepare for cravings by having distractions like water and snacks available.
The document discusses vapor cigarettes, also known as e-cigarettes. It outlines the benefits of vapor cigarettes over traditional cigarettes, such as being healthier, less expensive, and not producing odor or stains. It then describes how vapor cigarettes work using a battery-powered heating element to create a vapor from water in cartridges that can contain nicotine in various flavors. Finally, it provides tips on how to get started with vapor cigarettes, including reading reviews, finding the right brand, and learning proper usage.
This document is from an electronic cigarette retailer called Juicy Cigs. It introduces electronic cigarettes as a cheaper and healthier alternative to traditional cigarettes, with over 70 flavors of e-liquid available. It highlights that customers can save up to 80% compared to the cost of regular cigarettes. The site allows customers to browse different e-cigarette kits and accessories, read reviews from other customers, and learn more about electronic cigarettes.
This document provides summaries of articles on motoring, marine, and aviation topics relevant to the Hibiscus Coast region of New Zealand. It discusses driving tips for the summer months, a comparison of mineral fuels versus biofuel blends, and challenges around keeping Auckland moving in terms of transportation infrastructure and funding.
This document is a homepage for an electronic cigarette retailer called Juicy Cigs. It introduces electronic cigarettes as a cheaper and healthier alternative to traditional cigarettes, with over 70 flavors available. It highlights starter kits and individual products available at a range of prices. Customers can read reviews and find help and information about ordering and the company's policies.
The document discusses the dangers of smoking and provides tips to quit smoking. It notes that World No Tobacco Day is observed annually on May 31st to spread awareness of the health risks of tobacco, which contains over 4,000 chemicals, including 51 carcinogens. Common chemicals in cigarettes include carbon monoxide, nicotine, tar, arsenic, and cyanide. Smoking is linked to 22% of male deaths and 11% of female deaths. The document offers advice to help quit smoking such as using nicotine replacements, keeping busy, and avoiding others who smoke.
The document discusses various strategies for saving money as a consumer. It suggests making lists before shopping, buying generic brands instead of name brands, using coupons, and shopping at discount stores to save on groceries. Driving a fuel-efficient car, checking gas prices, and maintaining reasonable home temperatures can also save money on transportation and utility costs. With careful planning and consideration of long-term savings, consumers can accumulate significant savings over time.
This document discusses exporting blu e-cigarettes to Prague, Czech Republic. It begins with an introduction and background on blu e-cigs. Next, it provides a situation analysis of smoking rates and attitudes in the Czech Republic. It then estimates the target market size in Prague and provides a SWOT analysis. The document continues with sections on competition, product description, financial objectives, target markets, positioning, strategies, marketing mix, organizational structure, and conclusions. The overall aim is to analyze the viability and strategy for introducing blu e-cigs in the Czech market.
Similar to What Has Tobacco Cost You? Enough Already? (20)
Ethical Treatment Centers have been pushed aside by the dearth of unethical and shady operations in California and Florida. So, how to find the right place for your or a loved one?
We are so happy to be sober. These happy fish by http://bobschmitz.com express that joyousness. If you want some joy, consider rehab in Paradise, Serenity Vista Retreat in Panama. A different kind of addiction facility. Holistic, 12 Step, Discreet, find happiness.
People who have struggled with addiction don't take the little things for granted. Here's the after and before of a man who has recovered from a seemingly hopeless state of mind and body. Serenity Vista is a private pay, holistic, 12 Step based addiction recovery, life transformation retreat. Get away to tropical Panama and recover your life.
The eleventh step prayer of Alcoholics Anonymous has been appropriated from St Francis of Assisi. This beloved prayer has been a mantra of peace for hundreds of thousands of people for 600 years. Learning about spirituality in recovery is very important. At Serenity Vista Addiction Recovery Retreat in Panama, you will have an opportunity to explore what Higher Power or spirituality means to you. To recovery from the disease of addiction, consider private-pay, holistic rehab out of country. Surprisingly affordable. serenityvista.com for more info. send us an email, info@serenityvista.com
A newcomer to recovery needs to have the tool box filled. Here is one great tool in preventing relapse. Play the tape through to the end. Read here about putting this into action.
This document contains a 26-question self-assessment test to help determine if someone may be an alcoholic. It notes that answering yes to 2-8 questions indicates a good chance of being an alcoholic, while answering yes to more than 8 questions suggests a serious level of alcohol-related problems. The test contains questions about drinking behaviors, impacts of drinking, promises made about controlling drinking, and effects on health, work and relationships. It provides contact information at the end for a rehab facility for those seeking help.
Art therapy can be a very healing holistic aspect of recovery from addiction in drug rehab. Healing artist, Octavio Alvarez, illustrates work with clay in his art therapy workshops at Serenity Vista addiction treatment center of Boquete, Panama.
Alcoholics Anonymous was co-founded by Bill W. and Dr. Bob S. in 1935 to help alcoholics recover through a mutual-aid fellowship. Al-Anon was founded in 1951 by Lois W. and Anne B. to help families and friends of alcoholics deal with the effects of living with an alcoholic through sharing their experience, strength, and hope. Both fellowships are based on the 12-step program and have helped millions of people worldwide in their recovery process.
Addiction to alcohol, nicotine and other drugs, is a fatal disease. Those that have risen in the public eye present a tragic and compelling picture of people unable to find recovery. There is help, but one must be willing to accept that help, 24/7, one day at a time.
Not even the R.J. Reynolds family is immune to the Death Sentence of Nicotine Addiction. If you want to quit smoking before you die, get the help you need. Serenity Vista Nicotine, Alcohol and other drug addiction Rehab. www.serenityvista.com
Vintage slideshow of celebrities promoting the Tobacco Industry's Death Product. More often than not, when used as directed, this product even killed the celebrity. Take a look backwards to view the future of e-cigarette lies told by Big Smoke Companies.
A brief look at some Vintage Cigarette ads, contrasted with what we know today to be true. It is an amusing and unbelievable slide show, in a very perverse and sad way. Tobacco Industry Lies
The tobacco industry has been lying about the dangers of tobacco use since the very beginning. See these vintage cigarette ads using the health professionals as spokespeople. It is really chilling.
This document provides 10 tips and 2 bonus tips for addiction recovery illustrated by a chocolate Labrador named Ceiba who works at an addiction recovery retreat in Panama. The tips are meant to help those rethinking their rehabilitation process.
Cigarettes are the only products, when used as directed, will kill 50% of its users. Knowing this makes these cigarette commercials all that more ghastly.
If you are still smoking today, you are an active drug addict. Today there is residential drug treatment available for nicotine addicts in beautiful Panama. Serenity Vista Addiction Recovery Retreat www.serenityvista.com See our website for more information.
These slogans are great! Memorize some of them and amaze your sponser - or your sponsee. Recovery Slogans and Sobriety Sayings can be really helpful, coming to mind just when you need them.
Ceiba is a Chocolate Labrador Retriever in the Republic of Panama. She works at Serenity Vista Addiction Rehab as an Addict Whisperer. She understands.
More from Serenity Vista International Addiction Recovery Retreat (18)
5-hydroxytryptamine or 5-HT or Serotonin is a neurotransmitter that serves a range of roles in the human body. It is sometimes referred to as the happy chemical since it promotes overall well-being and happiness.
It is mostly found in the brain, intestines, and blood platelets.
5-HT is utilised to transport messages between nerve cells, is known to be involved in smooth muscle contraction, and adds to overall well-being and pleasure, among other benefits. 5-HT regulates the body's sleep-wake cycles and internal clock by acting as a precursor to melatonin.
It is hypothesised to regulate hunger, emotions, motor, cognitive, and autonomic processes.
Giloy in Ayurveda - Classical Categorization and SynonymsPlanet Ayurveda
Giloy, also known as Guduchi or Amrita in classical Ayurvedic texts, is a revered herb renowned for its myriad health benefits. It is categorized as a Rasayana, meaning it has rejuvenating properties that enhance vitality and longevity. Giloy is celebrated for its ability to boost the immune system, detoxify the body, and promote overall wellness. Its anti-inflammatory, antipyretic, and antioxidant properties make it a staple in managing conditions like fever, diabetes, and stress. The versatility and efficacy of Giloy in supporting health naturally highlight its importance in Ayurveda. At Planet Ayurveda, we provide a comprehensive range of health services and 100% herbal supplements that harness the power of natural ingredients like Giloy. Our products are globally available and affordable, ensuring that everyone can benefit from the ancient wisdom of Ayurveda. If you or your loved ones are dealing with health issues, contact Planet Ayurveda at 01725214040 to book an online video consultation with our professional doctors. Let us help you achieve optimal health and wellness naturally.
“Psychiatry and the Humanities”: An Innovative Course at the University of Mo...Université de Montréal
“Psychiatry and the Humanities”: An Innovative Course at the University of Montreal Expanding the medical model to embrace the humanities. Link: https://www.psychiatrictimes.com/view/-psychiatry-and-the-humanities-an-innovative-course-at-the-university-of-montreal
PGx Analysis in VarSeq: A User’s PerspectiveGolden Helix
Since our release of the PGx capabilities in VarSeq, we’ve had a few months to gather some insights from various use cases. Some users approach PGx workflows by means of array genotyping or what seems to be a growing trend of adding the star allele calling to the existing NGS pipeline for whole genome data. Luckily, both approaches are supported with the VarSeq software platform. The genotyping method being used will also dictate what the scope of the tertiary analysis will be. For example, are your PGx reports a standalone pipeline or would your lab’s goal be to handle a dual-purpose workflow and report on PGx + Diagnostic findings.
The purpose of this webcast is to:
Discuss and demonstrate the approaches with array and NGS genotyping methods for star allele calling to prep for downstream analysis.
Following genotyping, explore alternative tertiary workflow concepts in VarSeq to handle PGx reporting.
Moreover, we will include insights users will need to consider when validating their PGx workflow for all possible star alleles and options you have for automating your PGx analysis for large number of samples. Please join us for a session dedicated to the application of star allele genotyping and subsequent PGx workflows in our VarSeq software.
Breast cancer: Post menopausal endocrine therapyDr. Sumit KUMAR
Breast cancer in postmenopausal women with hormone receptor-positive (HR+) status is a common and complex condition that necessitates a multifaceted approach to management. HR+ breast cancer means that the cancer cells grow in response to hormones such as estrogen and progesterone. This subtype is prevalent among postmenopausal women and typically exhibits a more indolent course compared to other forms of breast cancer, which allows for a variety of treatment options.
Diagnosis and Staging
The diagnosis of HR+ breast cancer begins with clinical evaluation, imaging, and biopsy. Imaging modalities such as mammography, ultrasound, and MRI help in assessing the extent of the disease. Histopathological examination and immunohistochemical staining of the biopsy sample confirm the diagnosis and hormone receptor status by identifying the presence of estrogen receptors (ER) and progesterone receptors (PR) on the tumor cells.
Staging involves determining the size of the tumor (T), the involvement of regional lymph nodes (N), and the presence of distant metastasis (M). The American Joint Committee on Cancer (AJCC) staging system is commonly used. Accurate staging is critical as it guides treatment decisions.
Treatment Options
Endocrine Therapy
Endocrine therapy is the cornerstone of treatment for HR+ breast cancer in postmenopausal women. The primary goal is to reduce the levels of estrogen or block its effects on cancer cells. Commonly used agents include:
Selective Estrogen Receptor Modulators (SERMs): Tamoxifen is a SERM that binds to estrogen receptors, blocking estrogen from stimulating breast cancer cells. It is effective but may have side effects such as increased risk of endometrial cancer and thromboembolic events.
Aromatase Inhibitors (AIs): These drugs, including anastrozole, letrozole, and exemestane, lower estrogen levels by inhibiting the aromatase enzyme, which converts androgens to estrogen in peripheral tissues. AIs are generally preferred in postmenopausal women due to their efficacy and safety profile compared to tamoxifen.
Selective Estrogen Receptor Downregulators (SERDs): Fulvestrant is a SERD that degrades estrogen receptors and is used in cases where resistance to other endocrine therapies develops.
Combination Therapies
Combining endocrine therapy with other treatments enhances efficacy. Examples include:
Endocrine Therapy with CDK4/6 Inhibitors: Palbociclib, ribociclib, and abemaciclib are CDK4/6 inhibitors that, when combined with endocrine therapy, significantly improve progression-free survival in advanced HR+ breast cancer.
Endocrine Therapy with mTOR Inhibitors: Everolimus, an mTOR inhibitor, can be added to endocrine therapy for patients who have developed resistance to aromatase inhibitors.
Chemotherapy
Chemotherapy is generally reserved for patients with high-risk features, such as large tumor size, high-grade histology, or extensive lymph node involvement. Regimens often include anthracyclines and taxanes.
Nano-gold for Cancer Therapy chemistry investigatory projectSIVAVINAYAKPK
chemistry investigatory project
The development of nanogold-based cancer therapy could revolutionize oncology by providing a more targeted, less invasive treatment option. This project contributes to the growing body of research aimed at harnessing nanotechnology for medical applications, paving the way for future clinical trials and potential commercial applications.
Cancer remains one of the leading causes of death worldwide, prompting the need for innovative treatment methods. Nanotechnology offers promising new approaches, including the use of gold nanoparticles (nanogold) for targeted cancer therapy. Nanogold particles possess unique physical and chemical properties that make them suitable for drug delivery, imaging, and photothermal therapy.
Travel Clinic Cardiff: Health Advice for International TravelersNX Healthcare
Travel Clinic Cardiff offers comprehensive travel health services, including vaccinations, travel advice, and preventive care for international travelers. Our expert team ensures you are well-prepared and protected for your journey, providing personalized consultations tailored to your destination. Conveniently located in Cardiff, we help you travel with confidence and peace of mind. Visit us: www.nxhealthcare.co.uk
The skin is the largest organ and its health plays a vital role among the other sense organs. The skin concerns like acne breakout, psoriasis, or anything similar along the lines, finding a qualified and experienced dermatologist becomes paramount.
Discover the benefits of homeopathic medicine for irregular periods with our guide on 5 common remedies. Learn how these natural treatments can help regulate menstrual cycles and improve overall menstrual health.
Visit Us: https://drdeepikashomeopathy.com/service/irregular-periods-treatment/
Osvaldo Bernardo Muchanga-GASTROINTESTINAL INFECTIONS AND GASTRITIS-2024.pdfOsvaldo Bernardo Muchanga
GASTROINTESTINAL INFECTIONS AND GASTRITIS
Osvaldo Bernardo Muchanga
Gastrointestinal Infections
GASTROINTESTINAL INFECTIONS result from the ingestion of pathogens that cause infections at the level of this tract, generally being transmitted by food, water and hands contaminated by microorganisms such as E. coli, Salmonella, Shigella, Vibrio cholerae, Campylobacter, Staphylococcus, Rotavirus among others that are generally contained in feces, thus configuring a FECAL-ORAL type of transmission.
Among the factors that lead to the occurrence of gastrointestinal infections are the hygienic and sanitary deficiencies that characterize our markets and other places where raw or cooked food is sold, poor environmental sanitation in communities, deficiencies in water treatment (or in the process of its plumbing), risky hygienic-sanitary habits (not washing hands after major and/or minor needs), among others.
These are generally consequences (signs and symptoms) resulting from gastrointestinal infections: diarrhea, vomiting, fever and malaise, among others.
The treatment consists of replacing lost liquids and electrolytes (drinking drinking water and other recommended liquids, including consumption of juicy fruits such as papayas, apples, pears, among others that contain water in their composition).
To prevent this, it is necessary to promote health education, improve the hygienic-sanitary conditions of markets and communities in general as a way of promoting, preserving and prolonging PUBLIC HEALTH.
Gastritis and Gastric Health
Gastric Health is one of the most relevant concerns in human health, with gastrointestinal infections being among the main illnesses that affect humans.
Among gastric problems, we have GASTRITIS AND GASTRIC ULCERS as the main public health problems. Gastritis and gastric ulcers normally result from inflammation and corrosion of the walls of the stomach (gastric mucosa) and are generally associated (caused) by the bacterium Helicobacter pylor, which, according to the literature, this bacterium settles on these walls (of the stomach) and starts to release urease that ends up altering the normal pH of the stomach (acid), which leads to inflammation and corrosion of the mucous membranes and consequent gastritis or ulcers, respectively.
In addition to bacterial infections, gastritis and gastric ulcers are associated with several factors, with emphasis on prolonged fasting, chemical substances including drugs, alcohol, foods with strong seasonings including chilli, which ends up causing inflammation of the stomach walls and/or corrosion. of the same, resulting in the appearance of wounds and consequent gastritis or ulcers, respectively.
Among patients with gastritis and/or ulcers, one of the dilemmas is associated with the foods to consume in order to minimize the sensation of pain and discomfort.
Know the difference between Endodontics and Orthodontics.Gokuldas Hospital
Your smile is beautiful.
Let’s be honest. Maintaining that beautiful smile is not an easy task. It is more than brushing and flossing. Sometimes, you might encounter dental issues that need special dental care. These issues can range anywhere from misalignment of the jaw to pain in the root of teeth.
8. E. Collateral Damage$
Decreased value of home: 30% $_______
Decreased value of vehicle: 10 – 30% $_______
Burned or ruined furniture $_______
Burned or ruined clothes $_______
Fire in home or vehicle $_______
Increased costs of Life Insurance Policies $_______
Tobacco related dentistry $_______
Loss of work due to smoking related illness $_______
Medical costs $_______
Total $____________
9. Are you ready for
the Grand Total?
Before you add up all the
financial costs, let’s look
at other damages you
may not be aware of:
10. What about costs to those around you?
Did you:
• smoke while pregnant, or in the presence of pregnant
women?
• smoke around babies or children?
• enable minors to use nicotine?
• smoke around your, or other people’s pets?
• smoke in a prohibited or dangerous area?
• steal cigarettes?
• buy cigarettes while neglecting food or other necessities?
• throw your cigarette butts out the car window?
• empty your car ashtray on the street?
• use government or insurance money for products or
treatments related to your smoking?
• know that due to lost productivity, health and nicotine
withdrawal many times a day, employers are out $6000 for
every smoker?
11. What about costs to your relationships?
Did you:
• promise someone you would quit smoking and not?
• lie about your smoking to loved ones?
• choose only smoking friends or romantic partners?
• lose any relationships due to smoking?
• avoid activities like travel or movies, because you
couldn’t smoke freely?
• feel angry or abandoned by friends or family that quit
smoking?
12. What about cost to your self-respect?
Did you:
• scrounge & smoke someone else’s cigarette butts?
• ask for cigarettes from strangers?
• feel embarrassed or try to hide the smell on your
body, hair and clothes?
• feel embarrassed about yellowed teeth or fingers?
• feel guilt or shame due to smoking and/or inability
to stop?
• feel like a bad role model for your children or other
young people in your life?
13. Total of Financial Costs (A – E):
$_______________________
Grand Total of ALL COSTS:
________________________
________________________
Have you and your loved ones paid enough?
How much more are you willing to spend?
14. Nicotine Addiction:
How much more will it cost you?
www.serenityvista.com
Residential rehab for nicotine, alcohol and other drugs