Time's furious passing
•
0 likes•166 views
This poem expresses gratitude for life's endless possibilities and wonders. It contrasts those whose hearts and minds are numbed by routine with those who feel inspired and in awe of each moment. The poem calls on the reader to embrace life's transient nature with open hearts, wonder, and gratitude, and find joy in each moment rather than fearing its passing.
Report
Share
Report
Share
Download to read offline
Recommended
"Sharing Dhamma, Spreading Metta"
A Power Point Presentation of the Theme Song Lyrics for the 2002 10th Dhamma Youth Camp of PBHP. For the Young ( and Young at heart! )
Some Dhamma Messages in the Lyrics.
Speaking out
Presentation prepared for West Hill United's Affirming Celebration, December 4, 2011 featuring the photo essay Pride/Prejudice: Voices of LGBTQ Youth which is the work of internationally acclaimed photographer and activist, Rachelle Lee Smith. For more information on the work and upcoming book, see www.speakingout.com.
Bleed Red
An inspirational slide show created to accompany Babette Oliveira singing Ronnie Dunn's "Bleed Red"
Os principais serviços de streaming de filmes
Nesse trabalho, abordamos os principais serviços online que realizam streaming de filmes, como Netflix, Vivo Play, SKY Online, etc.
How to add RSS Feed in MS Outlook?
BY this presentation, one can easily understand the concept of RSS (Really Simple Syndication). Steps are provides to add Feed in MS Outlook. You will easily add RSS Feed in various editions of MS Outlook within few easy clicks
Get more :- http://www.msoutlooktools.com/category/rss/
Recommended
"Sharing Dhamma, Spreading Metta"
A Power Point Presentation of the Theme Song Lyrics for the 2002 10th Dhamma Youth Camp of PBHP. For the Young ( and Young at heart! )
Some Dhamma Messages in the Lyrics.
Speaking out
Presentation prepared for West Hill United's Affirming Celebration, December 4, 2011 featuring the photo essay Pride/Prejudice: Voices of LGBTQ Youth which is the work of internationally acclaimed photographer and activist, Rachelle Lee Smith. For more information on the work and upcoming book, see www.speakingout.com.
Bleed Red
An inspirational slide show created to accompany Babette Oliveira singing Ronnie Dunn's "Bleed Red"
Os principais serviços de streaming de filmes
Nesse trabalho, abordamos os principais serviços online que realizam streaming de filmes, como Netflix, Vivo Play, SKY Online, etc.
How to add RSS Feed in MS Outlook?
BY this presentation, one can easily understand the concept of RSS (Really Simple Syndication). Steps are provides to add Feed in MS Outlook. You will easily add RSS Feed in various editions of MS Outlook within few easy clicks
Get more :- http://www.msoutlooktools.com/category/rss/
How to Export Outlook Data File?
Need to know how to export Outlook data files? Use Export option to transfer all information of Outlook folders like: calendar, contacts, journals, task, inbox, outbox, sent items etc. and save it at different location as well as new device.
Common Problems with Outlook 2010
Solve common problems with Outlook 2010 with some inbuilt features of Microsoft Outlook. It helps you to create style in MS Outlook. Know more visit: http://goo.gl/hyhlby
Tecam Group: Technology Solutions_EN
What type of technologies does Tecam Group offer for Volatile Organic Compound emission treatment?
Tecam Group offers environmental technology solutions for the Industry to treat gas emissions and waste derived from production processes.
Tecam Group designs, manufactures and installs 2 types of technology:
1) Gas Emission Treatment:
a) Volatile Organic Compounds (VOC) abatement, through the following technology:
- Regenerative Thermal Oxidizer (RTO)
- Regenerative Catalytic Oxidizer (RCO)
- Adsorption Solution (Zeolite Rotor-Concentrator with RTO);
b) Combustion Gas Control;
c) Methane Treatment in Mines and Landfills;
2) Solid Waste Incineration for industrial, municipal, hospital, animal and naval vessel waste.
Tecam Group offers turn-key technological solutions. Our product is designed tailor-made to meet our customer’s specific requirements and incorporates high-end quality materials from top-tier suppliers. Tecam Group equipment complies with all EU equipment manufacturing requirements.
5 ways to convert social media in to smart marketing strategy
How to use social data insights for campaign strategies, implementation, media planning, development and reporting. 1. The 3 Ls of media analysis. 2. Social media audit. 3. Social media listening and analysis. 4. Insights and reporting. 5. Earned media value
Up for Auction a One of a Kind Necklace
Presenting an item for auction through the West Hill United Church 2015 Bid 'n' Buy Auction. Designed by you and handmade by Gretta Vosper, Minister at West Hill and author of the best-selling With or Without God: Why the Way We Live Is More Important than What We Believe. All items pictured have been designed and made by Gretta. This is your opportunity to own a special and rare piece of handmade jewelry. Bid by sending an email to finance@westhill.net before 6:00 Saturday March 28
We stand in brilliant light
The truth about what Earth is – what it’s made of, the universe in which it spins, the delicate balance that exists amongst its inhabitants – has increased over all our generations as we have learned more and more about it. Yet we are not satisfied for we do not know everything. In this moment, the light that is knowledge, surrounds us and yet evades us. So the quest continues...
Ours is a fluid milieu
We create institutions to help establish a world reflective of our values. But the world changes. We change. Sometimes, even our values change. And often, the institutions we create begin to struggle under the weight of their own success. We must learn to build fluidity into our institutions and so allow them to be a dynamic presence in our lives. Created for West Hill United, www.westhill.net
We cherish beauty
Inspired by Barbara Ehrenreich's quote: The real philanthropists in our society are the people who work for less than they can live actually live on because they are giving of their time and their energy and their talents all the time so that people like you can be dressed well and fed cheaply." Created for use at West Hill United, www.westhill.net
We pour ourselves
Taking time to consider how we are both different from one another and the same is an important part of our being in community. Written as a prayer for the non-exclusive spiritual community, West Hill. www.westhill.net
Daily offering
Exhausted, we often believe we have nothing left to give. But each day, in so many ways, the tally at the end is overflowing.
Focused moment prepared for West Hill United, www.westhill.net.
Rechemet compassion
The roots of the 14th century English word "compassion" are from the French for "struggle" and "together". But the roots of its Hebrew twin are much deeper and are shared with the word "rechemet" - "womb". This brings a whole new perspective to compassion ensuring that we consider that even as there is a time for us to hold one another compassionately, there is also a time when we must let go.
Focused moment prepared for West Hill United, www.westhill.net
I thou
Our relationships matter. Although we are responsible for only our part in them, the perspective we bring can either enhance or detract from creating a relationship of beauty and goodness. Twentieth century theologian Martin Buber captured the essence of relationship with his classic "I-Thou" reminding us that we have the option to treat the people, things, and ideas around us as sacred and holy or desecrate them by treated them as merely means to achieve our own personal goals. Focused Moment created for West Hill United.
Morning breaks
Focused moment created for Christmas morning at West Hill United, www.westhill.net, using the photographs of Morguefile.com user, mensatic, known in the real world as Emily Roesly, or Williamstown, New Jersy.
More Related Content
Viewers also liked
How to Export Outlook Data File?
Need to know how to export Outlook data files? Use Export option to transfer all information of Outlook folders like: calendar, contacts, journals, task, inbox, outbox, sent items etc. and save it at different location as well as new device.
Common Problems with Outlook 2010
Solve common problems with Outlook 2010 with some inbuilt features of Microsoft Outlook. It helps you to create style in MS Outlook. Know more visit: http://goo.gl/hyhlby
Tecam Group: Technology Solutions_EN
What type of technologies does Tecam Group offer for Volatile Organic Compound emission treatment?
Tecam Group offers environmental technology solutions for the Industry to treat gas emissions and waste derived from production processes.
Tecam Group designs, manufactures and installs 2 types of technology:
1) Gas Emission Treatment:
a) Volatile Organic Compounds (VOC) abatement, through the following technology:
- Regenerative Thermal Oxidizer (RTO)
- Regenerative Catalytic Oxidizer (RCO)
- Adsorption Solution (Zeolite Rotor-Concentrator with RTO);
b) Combustion Gas Control;
c) Methane Treatment in Mines and Landfills;
2) Solid Waste Incineration for industrial, municipal, hospital, animal and naval vessel waste.
Tecam Group offers turn-key technological solutions. Our product is designed tailor-made to meet our customer’s specific requirements and incorporates high-end quality materials from top-tier suppliers. Tecam Group equipment complies with all EU equipment manufacturing requirements.
5 ways to convert social media in to smart marketing strategy
How to use social data insights for campaign strategies, implementation, media planning, development and reporting. 1. The 3 Ls of media analysis. 2. Social media audit. 3. Social media listening and analysis. 4. Insights and reporting. 5. Earned media value
Viewers also liked (12)
[MindMap] A recommendation of the design for developers
[MindMap] A recommendation of the design for developers
5 ways to convert social media in to smart marketing strategy
5 ways to convert social media in to smart marketing strategy
More from Gretta Vosper
Up for Auction a One of a Kind Necklace
Presenting an item for auction through the West Hill United Church 2015 Bid 'n' Buy Auction. Designed by you and handmade by Gretta Vosper, Minister at West Hill and author of the best-selling With or Without God: Why the Way We Live Is More Important than What We Believe. All items pictured have been designed and made by Gretta. This is your opportunity to own a special and rare piece of handmade jewelry. Bid by sending an email to finance@westhill.net before 6:00 Saturday March 28
We stand in brilliant light
The truth about what Earth is – what it’s made of, the universe in which it spins, the delicate balance that exists amongst its inhabitants – has increased over all our generations as we have learned more and more about it. Yet we are not satisfied for we do not know everything. In this moment, the light that is knowledge, surrounds us and yet evades us. So the quest continues...
Ours is a fluid milieu
We create institutions to help establish a world reflective of our values. But the world changes. We change. Sometimes, even our values change. And often, the institutions we create begin to struggle under the weight of their own success. We must learn to build fluidity into our institutions and so allow them to be a dynamic presence in our lives. Created for West Hill United, www.westhill.net
We cherish beauty
Inspired by Barbara Ehrenreich's quote: The real philanthropists in our society are the people who work for less than they can live actually live on because they are giving of their time and their energy and their talents all the time so that people like you can be dressed well and fed cheaply." Created for use at West Hill United, www.westhill.net
We pour ourselves
Taking time to consider how we are both different from one another and the same is an important part of our being in community. Written as a prayer for the non-exclusive spiritual community, West Hill. www.westhill.net
Daily offering
Exhausted, we often believe we have nothing left to give. But each day, in so many ways, the tally at the end is overflowing.
Focused moment prepared for West Hill United, www.westhill.net.
Rechemet compassion
The roots of the 14th century English word "compassion" are from the French for "struggle" and "together". But the roots of its Hebrew twin are much deeper and are shared with the word "rechemet" - "womb". This brings a whole new perspective to compassion ensuring that we consider that even as there is a time for us to hold one another compassionately, there is also a time when we must let go.
Focused moment prepared for West Hill United, www.westhill.net
I thou
Our relationships matter. Although we are responsible for only our part in them, the perspective we bring can either enhance or detract from creating a relationship of beauty and goodness. Twentieth century theologian Martin Buber captured the essence of relationship with his classic "I-Thou" reminding us that we have the option to treat the people, things, and ideas around us as sacred and holy or desecrate them by treated them as merely means to achieve our own personal goals. Focused Moment created for West Hill United.
Morning breaks
Focused moment created for Christmas morning at West Hill United, www.westhill.net, using the photographs of Morguefile.com user, mensatic, known in the real world as Emily Roesly, or Williamstown, New Jersy.
Because i am a girl
Focused moment prepared to accompany All About Eve, the Because I Am A Girl presentation written by Rick Miller and made available for use across Canada through the Plan Canada website. All photos are from Plan Canada's Because I Am a Girl website.
Like the line between
Focused moment for West Hill United's Annual LGBTQ Affirming Celebration. www.westhill.net, December 4, 2011
What you want
Focused moment created from the photography of jschumacher, morguefile.com, for use at West Hill United, www.westhill.net
We are the future now
Focused Moment for October 30, 2011 for West Hill United, www.westhill.net featuring photos from the Occupy websites as well as my own work.
Dancers of the very edges of things
A focused moment created for use at Widen the Embrace, a conference of the Canadian Centre for Progressive Christianity, London, October 21-23, 2011. It was inspired by a reading by Victoria Safford.
We do not live by bread alone
Focused moment prepared for West Hill United for October 2, 2011 - World Wide Communion Sunday, www.westhill.net
Amorphous the morning
Inspired by Mark Nichol's list of 100 Beautiful and Ugly Words, this focused moment was written for West Hill United, www.westhill.net, September 4, 2011
More from Gretta Vosper (20)
Recently uploaded
Evaluation of antidepressant activity of clitoris ternatea in animals
Evaluation of antidepressant activity of clitoris ternatea in animals
Physiology of Chemical Sensation of smell.pdf
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journey
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
Follow us on: Pinterest
Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Are There Any Natural Remedies To Treat Syphilis.pdf
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
The Normal Electrocardiogram - Part I of II
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
BENIGN PROSTATIC HYPERPLASIA.BPH. BPHpdf
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Alcohol_Dr. Jeenal Mistry MD Pharmacology.pdf
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Antiulcer drugs Advance Pharmacology .pptx
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdf
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
KDIGO 2024 guidelines for diabetologists
KDIGO guidelines 2024 for evaluation and management of CKD, related to diabetes and management of diabetic kidney disease
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Physiology of Special Chemical Sensation of Taste
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Surgical Site Infections, pathophysiology, and prevention.pptx
A short overview presentation for medical allied health care professionals and under graduate medical courses
Recently uploaded (20)
Evaluation of antidepressant activity of clitoris ternatea in animals
Evaluation of antidepressant activity of clitoris ternatea in animals
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journey
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journey
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...
Are There Any Natural Remedies To Treat Syphilis.pdf
Are There Any Natural Remedies To Treat Syphilis.pdf
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdf
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...
Surgical Site Infections, pathophysiology, and prevention.pptx
Surgical Site Infections, pathophysiology, and prevention.pptx
Time's furious passing
- 1. An eternity of thanksgiving and still the world would turn and turn into new beginnings,
- 3. There can be no end to gratitude,
- 4. to hearts stilled in amazement,
- 5. to breath stopped by wonder,
- 6. to minds sparked by possibility.
- 7. But we – whose hearts beat in staid, sedate and steady rhythm,
- 8. whose breath is measured, unengaged, u
- 9. whose minds are numbed by the length of our days –
- 10. we could starve for lack of inspiration.
- 11. May we feel the rush of time before us approaching with a fierce, irreversible zeal.
- 12. May we boldly open our arms, stand naked before its turbulent truth,
- 13. and know that it is all we ever have to lose.
- 14. Then, with hearts caught in wonder, grace, and gratitude,
- 15. may we dance in time’s furious passing
- 16. and learn to love the dance.