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This UCP1 protein allows the protons (H +
) of the mitochondrial intermembrane space to enter
the mitochondrial matrix without going through the ATP synthase. This bypass represents a
shortcut for protons and uncouples (i.e. eliminates the interrelationship between) the
following two processes:
The entry of protons inside the mitochondrial matrix, following their concentration gradient.
The phosphorylation of ADP into ATP by the ATP synthase.
It is this uncoupling that gave the protein its name: uncoupling protein 1 (UCP1).
The following figure shows the location of UCP1 when it is expressed (synthesized) in the
brown adipose tissues (BAT) of hibernating mammals.
Based on the UCP1 protein structure shown earlier, and based on the figure above, what type of
protein is UCP1?
Question 12 options:
a) A primary active transporter.
b) A passive transporter.
c) A motor protein.
d) A coenzyme.
e)A secondary active transporter
Intermembrane space

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This UCP1 protein allows the protons (H+) of the mitochondrial interme.pdf

  • 1. This UCP1 protein allows the protons (H + ) of the mitochondrial intermembrane space to enter the mitochondrial matrix without going through the ATP synthase. This bypass represents a shortcut for protons and uncouples (i.e. eliminates the interrelationship between) the following two processes: The entry of protons inside the mitochondrial matrix, following their concentration gradient. The phosphorylation of ADP into ATP by the ATP synthase. It is this uncoupling that gave the protein its name: uncoupling protein 1 (UCP1). The following figure shows the location of UCP1 when it is expressed (synthesized) in the brown adipose tissues (BAT) of hibernating mammals. Based on the UCP1 protein structure shown earlier, and based on the figure above, what type of protein is UCP1? Question 12 options: a) A primary active transporter. b) A passive transporter. c) A motor protein. d) A coenzyme. e)A secondary active transporter Intermembrane space