The Virtual Museum Report summarizes the activities of the Animal Demography Unit's Virtual Museum in 2014. It notes that over 56,000 records were added in 2014, a 76% increase over 2013. This pushed the total records in the Virtual Museum database past the 1 million record milestone. Several citizen science projects like LepiMAP contributed large numbers of records. New projects in mushrooms, lacewings, and orchids also joined. A key publication was an atlas and red list of South African reptiles. Work is ongoing to red list mammals with a call for more mammal records.
Jose Bolante became acquainted with the Negrito communities of Panay and a strong bond based on understanding and friendship developed between him and the Negritos. He compiled a monograph on their material culture which is of greater value than those produced by present-day ‘institutionalized’ professionals.
The NMC Horizon Report > 2012 Museum Edition, is a co-production with the Marcus Institute for Digital Education in the Arts (MIDEA), and examines emerging technologies for their potential impact on and use in education and interpretation within the museum environment. The international composition of the advisory board that chose the technologies, trends, and challenges reflects the care with which a global perspective for the report was assembled. While there are many local factors affecting the adoption and use of emerging technologies in museums, there are also issues that transcend regional boundaries and questions we all face. It was with this in mind that the report was created. View the work of the advisory board on the official museum wiki at museum.wiki.nmc.org.
Highlights from the NMC Horizon Report > 2012 Museum Edition v.2Alex Freeman
The NMC Horizon Report > 2012 Museum Edition focuses on emerging technology and its applications to museum education and interpretation, and introduces six emerging technologies or practices that are likely to enter mainstream use in museums over the next one to five years. This talk will provide an overview of the six emerging technologies and their relevance to museums.
NMC Horizon Report Project Preview -- 2012 Museum Edition presented by Holly Witchey and Alex Freeman at the 2012 MCN Conference in Seattle, Washington on Thursday, November 8, 2012.
Presentation for the NMC Horizon Report > 2016 Higher Education Edition (from...New Media Consortium
The NMC Horizon Report > 2016 Higher Education Edition was presented by Chief Executive Officer of the NMC Larry Johnson, Senior Researcher Bryan Alexander, and ELI Associate Director Veronica Diaz at the 2016 EDUCAUSE Learning Initiative Annual Meeting. This presentation is from the release event. Download the report at http://go.nmc.org/2016-he.
Jose Bolante became acquainted with the Negrito communities of Panay and a strong bond based on understanding and friendship developed between him and the Negritos. He compiled a monograph on their material culture which is of greater value than those produced by present-day ‘institutionalized’ professionals.
The NMC Horizon Report > 2012 Museum Edition, is a co-production with the Marcus Institute for Digital Education in the Arts (MIDEA), and examines emerging technologies for their potential impact on and use in education and interpretation within the museum environment. The international composition of the advisory board that chose the technologies, trends, and challenges reflects the care with which a global perspective for the report was assembled. While there are many local factors affecting the adoption and use of emerging technologies in museums, there are also issues that transcend regional boundaries and questions we all face. It was with this in mind that the report was created. View the work of the advisory board on the official museum wiki at museum.wiki.nmc.org.
Highlights from the NMC Horizon Report > 2012 Museum Edition v.2Alex Freeman
The NMC Horizon Report > 2012 Museum Edition focuses on emerging technology and its applications to museum education and interpretation, and introduces six emerging technologies or practices that are likely to enter mainstream use in museums over the next one to five years. This talk will provide an overview of the six emerging technologies and their relevance to museums.
NMC Horizon Report Project Preview -- 2012 Museum Edition presented by Holly Witchey and Alex Freeman at the 2012 MCN Conference in Seattle, Washington on Thursday, November 8, 2012.
Presentation for the NMC Horizon Report > 2016 Higher Education Edition (from...New Media Consortium
The NMC Horizon Report > 2016 Higher Education Edition was presented by Chief Executive Officer of the NMC Larry Johnson, Senior Researcher Bryan Alexander, and ELI Associate Director Veronica Diaz at the 2016 EDUCAUSE Learning Initiative Annual Meeting. This presentation is from the release event. Download the report at http://go.nmc.org/2016-he.
Crowdsourcing, computer vision, and data science for conservation - Tanya Ber...Sri Ambati
Presented at #H2OWorld 2017 in Mountain View, CA.
Learn more about H2O.ai: https://www.h2o.ai/.
Follow @h2oai: https://twitter.com/h2oai.
- - -
Photographs, taken by field scientists, tourists, automated cameras, and incidental photographers, are the most abundant source of data on wildlife today. Wildbook is an autonomous computational system that starts from massive collections of images and, by detecting various species of animals and identifying individuals, combined with sophisticated data management, turns them into high-resolution information database, enabling scientific inquiry, conservation, and citizen science. We will present the computer vision, machine learning, and data science under the hood of Wildbook.
Dr. Tanya Berger-Wolf is a Professor of Computer Science at the University of Illinois at Chicago, where she heads the Computational Population Biology Lab. As a computational ecologist, her research is at the unique intersection of computer science, wildlife biology, and social sciences. Berger-Wolf is also a co-founder of the conservation software non-profit Wildbook, which enables wildlife research and conservation from crowdsourced photographs with computer vision and AI. Berger-Wolf holds a Ph.D. in Computer Science from the University of Illinois at Urbana-Champaign. She received numerous awards for her research and mentoring, including NSF CAREER and AWIS Chicago Innovator Award.
This slideshow features the various projects within the Virtual Museum of the Animal Demography Unit, Department of Biological Sciences, University of Cape Town. The Virtual Museum (VM) provides the platform for citizen scientists to contribute to biodiversity projects. Your photos can count for biodiversity conservation!
iSpot southern Africa- SANBI’s exciting new citizen science initiativeMark Simon
http://findtalentworldwide.com Check out there is a new App. that lets you broadcast your CV and Video to advertise yourself for work worldwide - Immediate exposure? You got talent we have a platform.
Addressing key scientific questions through the development of tools that use multiple data resources.
Todd Witcher, Executive Director of Discover Life In America, spoke about the Smokies Biodiversity project at the 2009 East Tennessee Preservation Conference.
This slideshow uses the data from the Second Southern African Bird Atlas Project (SABAP2) to show how Spotted Flycathers arrive and depart from southern Africa
Crowdsourcing, computer vision, and data science for conservation - Tanya Ber...Sri Ambati
Presented at #H2OWorld 2017 in Mountain View, CA.
Learn more about H2O.ai: https://www.h2o.ai/.
Follow @h2oai: https://twitter.com/h2oai.
- - -
Photographs, taken by field scientists, tourists, automated cameras, and incidental photographers, are the most abundant source of data on wildlife today. Wildbook is an autonomous computational system that starts from massive collections of images and, by detecting various species of animals and identifying individuals, combined with sophisticated data management, turns them into high-resolution information database, enabling scientific inquiry, conservation, and citizen science. We will present the computer vision, machine learning, and data science under the hood of Wildbook.
Dr. Tanya Berger-Wolf is a Professor of Computer Science at the University of Illinois at Chicago, where she heads the Computational Population Biology Lab. As a computational ecologist, her research is at the unique intersection of computer science, wildlife biology, and social sciences. Berger-Wolf is also a co-founder of the conservation software non-profit Wildbook, which enables wildlife research and conservation from crowdsourced photographs with computer vision and AI. Berger-Wolf holds a Ph.D. in Computer Science from the University of Illinois at Urbana-Champaign. She received numerous awards for her research and mentoring, including NSF CAREER and AWIS Chicago Innovator Award.
This slideshow features the various projects within the Virtual Museum of the Animal Demography Unit, Department of Biological Sciences, University of Cape Town. The Virtual Museum (VM) provides the platform for citizen scientists to contribute to biodiversity projects. Your photos can count for biodiversity conservation!
iSpot southern Africa- SANBI’s exciting new citizen science initiativeMark Simon
http://findtalentworldwide.com Check out there is a new App. that lets you broadcast your CV and Video to advertise yourself for work worldwide - Immediate exposure? You got talent we have a platform.
Addressing key scientific questions through the development of tools that use multiple data resources.
Todd Witcher, Executive Director of Discover Life In America, spoke about the Smokies Biodiversity project at the 2009 East Tennessee Preservation Conference.
This slideshow uses the data from the Second Southern African Bird Atlas Project (SABAP2) to show how Spotted Flycathers arrive and depart from southern Africa
SABAP2 is the most important bird conservation project in South Africa. This is because conservation interventions depend on knowing the distributions of species and how they are changing. This is a slideshare of the Barn Swallow Seasonality, Migration and Breeding.
This slideshow shows the SABAP2 coverage maps, from when the project started in 2007. The maps are shown from mid year (July) to the following mid year (June). This is the most important bird conservation project in the region. Trying to conserve birds without having up-to-date distribution maps is winking in the dark. The slideshow ends with "thank yous" and "pleases". Please do read these carefully.
Les Underhill, Animal Demography Unit, University of Cape Town presented the AP Leventis Lecture at the University of Jos, Nigeria, on 11 November 2014. The event was hosted by the AP Leventis Ornithological Research Institute (APLORI), Amurum Forest, Jos, Plateau State, Nigeria. The topic of the lecture was "Biodiversity Conservation: how to make a difference"
How to create a species list from the Virtual Museum data -- find out how you can extract a species list for a grid cell, province or nature reserve for any of the projects in the Virtual Museum
How to register as a Citizen Scientist with the Animal Demography Unit - get involved with our various citizen science projects and make a difference for biodiversity conservation in Africa!
The Animal Demography Unit's Citizen Scientist Day at the Walter Sisulu National Botanical Gardens in Roodepoort, Gauteng. Held on the 16th of August 2014. Thank you to everyone that attended this great event!
More from The Biodiversity & Development Institute (9)
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
The increased availability of biomedical data, particularly in the public domain, offers the opportunity to better understand human health and to develop effective therapeutics for a wide range of unmet medical needs. However, data scientists remain stymied by the fact that data remain hard to find and to productively reuse because data and their metadata i) are wholly inaccessible, ii) are in non-standard or incompatible representations, iii) do not conform to community standards, and iv) have unclear or highly restricted terms and conditions that preclude legitimate reuse. These limitations require a rethink on data can be made machine and AI-ready - the key motivation behind the FAIR Guiding Principles. Concurrently, while recent efforts have explored the use of deep learning to fuse disparate data into predictive models for a wide range of biomedical applications, these models often fail even when the correct answer is already known, and fail to explain individual predictions in terms that data scientists can appreciate. These limitations suggest that new methods to produce practical artificial intelligence are still needed.
In this talk, I will discuss our work in (1) building an integrative knowledge infrastructure to prepare FAIR and "AI-ready" data and services along with (2) neurosymbolic AI methods to improve the quality of predictions and to generate plausible explanations. Attention is given to standards, platforms, and methods to wrangle knowledge into simple, but effective semantic and latent representations, and to make these available into standards-compliant and discoverable interfaces that can be used in model building, validation, and explanation. Our work, and those of others in the field, creates a baseline for building trustworthy and easy to deploy AI models in biomedicine.
Bio
Dr. Michel Dumontier is the Distinguished Professor of Data Science at Maastricht University, founder and executive director of the Institute of Data Science, and co-founder of the FAIR (Findable, Accessible, Interoperable and Reusable) data principles. His research explores socio-technological approaches for responsible discovery science, which includes collaborative multi-modal knowledge graphs, privacy-preserving distributed data mining, and AI methods for drug discovery and personalized medicine. His work is supported through the Dutch National Research Agenda, the Netherlands Organisation for Scientific Research, Horizon Europe, the European Open Science Cloud, the US National Institutes of Health, and a Marie-Curie Innovative Training Network. He is the editor-in-chief for the journal Data Science and is internationally recognized for his contributions in bioinformatics, biomedical informatics, and semantic technologies including ontologies and linked data.
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
This pdf is about the Schizophrenia.
For more details visit on YouTube; @SELF-EXPLANATORY;
https://www.youtube.com/channel/UCAiarMZDNhe1A3Rnpr_WkzA/videos
Thanks...!
1. Virtual Museum Report 2014
Les Underhill and Megan Loftie-Eaton – Animal Demography Unit
University of Cape Town
2. Knowing the ranges of species
and how they are changing is
key to proper biodiversity
conservation and can act as an
early warning system if a
species might be in trouble.
3. Is a species' range expanding
or contracting? If we don't
know this how can we make
proper decisions regarding
its conservation?
4. During 2014 we added 56787
records to the Virtual
Museum database. The total
for 2013 was 32249. That is a
76% increase!
5. During 2014 we quietly passed the
one million records milestone. The
total number of records in the Virtual
Museum database has grown to
1 029 368 records!! This includes
non-photographic records, bulk
uploads, and museum specimens, for
butterflies, frogs, reptiles and
mammals.
6. LepiMAP was the big
achiever with 21502 records
for 2014. Well done
LepiMAPpers!
7. Three new projects joined
the Virtual Museum family
this year: MushroomMAP,
LacewingMAP, and
OrchidMAP
8. The big publishing event of 2014 was the
Atlas and Red List of the Reptiles of South
Africa, Lesotho, and Swaziland. This book
was the culmination of the Southern African
Reptile Conservation Assessment (SABCA)
which has now become ReptileMAP
9. The Red Listing of Mammals is
underway! Please make a special
effort to submit your mammal
records to MammalMAP
10. The instructions for submitting records to the Virtual
Museum are available at
http://www.slideshare.net/meganloftieeaton/how-to-
submit-records-to-the-animal-demography-units-virtual-
museums-28710898