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The Healing Brain: Integrating Positive
Psychology, 12-Step & Neurochemistry into a
Model for Recovery
5th annual Lifestyle Intervention Conference
October 5, 2015
8:30 – 10:00
Ralph E Carson, PhD, RD
Nutritionist & Exercise Physiologist
www.FitRxBrentwood
rcarson@contactaac.com
What Would You like to Say You
Achieved Following Treatment?
And What Will That Make You?
• People in the US rank HAPPINESS as their
most important goal
Duchene Smile
Authentic
Pseudo-
How Can You Tell if Someone is Happy?
• Zygomaticus
• Obicularis oculi
– Constrict eyes
– Raise cheeks
– Gather skin towards
bridge of nose
STRESS
Left Prefrontal Cortex Right Prefrontal Cortex
Prefrontal
Cortex
Happiness Anger
Fear
Disgust
Striatum or Nucleus Accumbens
Dopamine Circuit
Left Prefrontal Cortex Right Prefrontal Cortex
Prefrontal
Cortex
Happiness Anger
Fear
Disgust
Pleasantness Circuit
(Davidson ’98, ’00, ’02, ‘03a, ‘03b, ‘07; Tomarken ’92; Lyubomirsky ’07 )
NEUROGENESIS
What Makes Humans Unique?
• Ability to think
and act in the future
• Uniquely strong herd instinct
Herd Instinct
Orbitofrontal Cortex
What Medications Besides Antibiotics
and Chemotherapy Cure a Disease?
• None
• The Body
Heals Itself
• Medications
• Act as a catalyst for
healing
• Prevent or reduce the
risk of disease
• Mitigate Symptoms
Asked High School Students
“What Would make You Happy?”
• Money
• Beauty
• Popularity
• Residence
• Education
• Age
• Health
Certain Problems for
which there are no
Solutions!
• Economic Collapse
– Higher Taxes
– Real Estate Bust
– Stock Market Crash
• Poverty
– Jobless rate
• Disease
– Cancer
– Alzheimer’s
• Community unrest
– Aurora CO
• Terrorism
– Iran
– Afghanistan
• Global Warming
– Hurricanes; Tornados
Worry, Unresolved Stress: Amygdala; HPA
Cortisol is Neurotoxic (Schoenfeld ‘12)
Stress Damages the
Brain and Alters Repair
(Kim ‘02)
• Loss of dendritic spines
(Chen ’10; Muchu ‘11)
• 8% reduction in
Hippocampal volume
(Bremner’00; Carrioin ’06; Iris-Tatjana ‘07)
Entropy: Organization → Disorganization
1977 Cancer
Survival Rate:
5% lived >2 years
20O7 Cancer
Survival Rate:
80% lived > 5 years
(Howlander ‘12)
HOPE: Thinking & Acting Positively in the Future
We Judge Science by whether or not
it agrees with what we believe
• Placebo:
– Believe in the act of
being treated
• Nocebo
– Believe we will get sick
• Results is what matters;
and not how we got
there
Those with less hope have
more heart problems
(Pedersen & Sherer ‘10; Sherer ‘07)
• Genes that ↑ heart
disease are the same
genes that make us
prone to depression
• Less Hopeful
– More vulnerable
– Greater symptoms
– Lack energy to exercise
– Follow a poor diet
– Less likely to take
medications
• Luck
• Optimism
• Wishful thinking
• Coincidence
• Higher Power
• Recovery Community
• Personal Epiphany
• Others Believe in you
Assurance of
Hope
God spot (Peel ’09; Urgesi ‘10; Kapogianis ‘09a; ‘09b)
God Gene (Hammer ‘04; Silvaira ‘08; Kluger ’04; Newberg ‘09)
Identify Your Personal
Strengths and Virtues
And Use Them
for the
Betterment of
Mankind
FORGIVENESS
Health Problems: Unforgiveness
(Tibbits ‘06; Worthington ‘05, ‘07; Landers Row ‘08)
• High Blood Pressure
• Elevated heart rate
• Muscle tension
• Immunosuppressant
• Addictions
• Medications
• Cortisol: Neural Cell
Death (Root ‘09; Cunningham-Bussel
‘09)
• Who Are You
Hurting if You
Don’t Forgive?
Rudy Tomjonovich
12/9/77
To Not Forgive Is Like Drinking Poison
• And Hoping Someone Else Dies
Buddah
Meditation
EEG
Psyche Grad Students Buddhist Monks
Removing Necrotic Skin
from Burn Patient
Left Prefrontal Cortex Right Prefrontal Cortex
Prefrontal
Cortex
Happiness Anger
Fear
Disgust
Listened to Abused
Screaming
Compassion & Empathy
(Kluger ’07, Panksepp 2009; Decety ’08; Schulman,
Hauser)
• Compassion:
Recognizing the
suffering of others and
wishing for that
suffering to be
alleviated
• Empathy: The ability to
imagine what someone
else might be feeling
Gratitude
Health Benefits:
Gratitude
(Emmons ’03; ‘04; Norville ‘07; McCarty ‘95;
Oelklaus ‘08; Danner ‘01; Kern ‘04)
• Addiction recovery
• Weight management
• Reduce pain and
headaches
• Lower blood pressure
• Improve
cardiovascular
function
• Improve longevity
• Reduce cortisol
Altruism
(Andreoni ‘09; Dietin ‘10; Smith ‘09)
• Giving without
expectation of
reward
• Put welfare of
other’s ahead of
their own
Relationships
• Relationships: Single
most important factor
responsible for survival
(Berscheid ‘07)
• Selfishness: Root cause
of addiction (Pagano ‘11)
Confide: One whom you can be candid
without fear of reprisal or stigma
• Survey: How many
people can you confide
in?
• 1985: Three
(10% only 1)
• 2004: Two
(25% no one; 25% 1)
(McPherson ’06)
What Does This Plan Sound Like?
Study the Great Religions
of the World
• Christianity
• Judaism
• Islam
• Buddhism
• Hinduism
12 – STEP
(Addictions)
Positive Psychology
(Neurochemisty)
Christian Values
(Fruits of the Spirit)
Higher Power - Faith Belief God - Faith
Hope
(1-3)
Hope Hope
Inventory Faults
(4,5 10)
Strengths & Virtues Self-control
Forgiveness
(6-9)
Forgiveness Peace
Meditation – Prayer
(11)
Compassion/
Empathy
Kindness
Service
(12)
Gratitude & Altruism
Gentleness &
Generosity
Support Groups
Sponsor
Relationships Agape - Love
Sobriety Happiness Joy
Sensory - Thalamo -
Cortical
• Relay station: Filters
what gets through
– Auditory
– Visual
– Associative
– Somatosensory
• Gustatory
• Touch
– Prefrontal Cortex
– Motor
Thalamus: D2 Receptor Deficiency
• ↓Thalamic D2BP (D2
binding potential)
– ↓ Filtering
– ↑ Cortical excitement
– ↑ Creativity
• Reduced in (Santosa ‘07)
– Addiction
– ADHD
– Bipolar
– Schizophrenia
Change:
Letting Go
• “Change is inevitable; the
only sure thing in life is
change “ unknown
• “Change is inevitable;
suffering is optional” Zen
Buddhism
• “If we don’t change, we
don’t grow. If we don’t
grow, we are not really
living” Gail Sheehy
• “Life is pleasant. Death is
peaceful. It’s the transition
that is troublesome” Isaac
Asimov
WE DON’T Have to HIT BOTTOM
• “We rarely change
when life is cool and
comfortable; we change
when we feel the heat”
• “Life is like a bicycle: In
order to sat balance you
have got to keep
moving”
• “A turtle doesn’t make
progress until it sticks
its head out….”
• How many psychologist
does it take to change a
light bulb?
• “We change our
behavior when the
pain of staying the
same becomes
greater than the
pain of changing”
(Cloud ‘10; Mesiti ‘06)
• “Get over it”
• “It’s time to get real”
• “Is it working for you”
• “Awareness without
action is worthless”
• “Keep doing what you
have always done and
you will keep on getting
what you have always
gotten” Ed Foreman
• “Insanity is doing the
same thing over and
over again and
expecting it to come out
differently”
Choose Your Battles Carefully
in the world of public opinion
“People judge science by
whether or not it agrees
with what they believe”
“What matters is the
results; not how you got
their”
“Clinical guidelines are
consensus based and not
evidenced based”
“Statistically significant is
not always clinically
significant”
Serenity Prayer
(Letting Go)
• God, grant me the -
• Serenity to accept the things I cannot change,
• Courage to change the things I can,
• Wisdom to know the difference
• Dr. Reinhold Niebuhr
Resilience & Cross Addiction
• Whack down one
addiction or compulsion
and another pops up
• Resilience: Ability to
cope with stress and
adversity
Recovery
• Process rather than an outcome
– Give yourself permission to take time to make new
neural connections
• Journey to rediscover the “True Self”
– Overcome problems that stand in your way
– Feel Feelings
– Reclaim your Gifts and Potentials
– Align behavior with personal virtues
– Fulfill your purpose in life
God's Wheel
by Shel Silverstein (Silverstiein ’81)
God says to me with kind of a smile,
"Hey how would you like to be God awhile
And steer the world?"
"Okay," says I, "I'll give it a try.
Where do I set?
How much do I get?
What time is lunch?
When can I quit?"
"Gimme back that wheel," says God,
"I don't think you're quite ready yet."

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The Healing Brain: Integrating Positive Psychology, 12-Step, and Neurochemistry in Model for Recovery

  • 1. The Healing Brain: Integrating Positive Psychology, 12-Step & Neurochemistry into a Model for Recovery 5th annual Lifestyle Intervention Conference October 5, 2015 8:30 – 10:00 Ralph E Carson, PhD, RD Nutritionist & Exercise Physiologist www.FitRxBrentwood rcarson@contactaac.com
  • 2. What Would You like to Say You Achieved Following Treatment? And What Will That Make You? • People in the US rank HAPPINESS as their most important goal
  • 3. Duchene Smile Authentic Pseudo- How Can You Tell if Someone is Happy?
  • 4. • Zygomaticus • Obicularis oculi – Constrict eyes – Raise cheeks – Gather skin towards bridge of nose
  • 6.
  • 7. Left Prefrontal Cortex Right Prefrontal Cortex Prefrontal Cortex Happiness Anger Fear Disgust
  • 8. Striatum or Nucleus Accumbens Dopamine Circuit
  • 9. Left Prefrontal Cortex Right Prefrontal Cortex Prefrontal Cortex Happiness Anger Fear Disgust
  • 10. Pleasantness Circuit (Davidson ’98, ’00, ’02, ‘03a, ‘03b, ‘07; Tomarken ’92; Lyubomirsky ’07 )
  • 12.
  • 13. What Makes Humans Unique? • Ability to think and act in the future • Uniquely strong herd instinct
  • 16. What Medications Besides Antibiotics and Chemotherapy Cure a Disease? • None • The Body Heals Itself • Medications • Act as a catalyst for healing • Prevent or reduce the risk of disease • Mitigate Symptoms
  • 17. Asked High School Students “What Would make You Happy?” • Money • Beauty • Popularity • Residence • Education • Age • Health
  • 18.
  • 19. Certain Problems for which there are no Solutions! • Economic Collapse – Higher Taxes – Real Estate Bust – Stock Market Crash • Poverty – Jobless rate • Disease – Cancer – Alzheimer’s • Community unrest – Aurora CO • Terrorism – Iran – Afghanistan • Global Warming – Hurricanes; Tornados
  • 20. Worry, Unresolved Stress: Amygdala; HPA Cortisol is Neurotoxic (Schoenfeld ‘12)
  • 21. Stress Damages the Brain and Alters Repair (Kim ‘02) • Loss of dendritic spines (Chen ’10; Muchu ‘11) • 8% reduction in Hippocampal volume (Bremner’00; Carrioin ’06; Iris-Tatjana ‘07)
  • 22. Entropy: Organization → Disorganization 1977 Cancer Survival Rate: 5% lived >2 years 20O7 Cancer Survival Rate: 80% lived > 5 years (Howlander ‘12)
  • 23.
  • 24. HOPE: Thinking & Acting Positively in the Future
  • 25.
  • 26. We Judge Science by whether or not it agrees with what we believe • Placebo: – Believe in the act of being treated • Nocebo – Believe we will get sick • Results is what matters; and not how we got there
  • 27. Those with less hope have more heart problems (Pedersen & Sherer ‘10; Sherer ‘07) • Genes that ↑ heart disease are the same genes that make us prone to depression • Less Hopeful – More vulnerable – Greater symptoms – Lack energy to exercise – Follow a poor diet – Less likely to take medications
  • 28. • Luck • Optimism • Wishful thinking • Coincidence • Higher Power • Recovery Community • Personal Epiphany • Others Believe in you Assurance of Hope
  • 29. God spot (Peel ’09; Urgesi ‘10; Kapogianis ‘09a; ‘09b) God Gene (Hammer ‘04; Silvaira ‘08; Kluger ’04; Newberg ‘09)
  • 30. Identify Your Personal Strengths and Virtues And Use Them for the Betterment of Mankind
  • 32. Health Problems: Unforgiveness (Tibbits ‘06; Worthington ‘05, ‘07; Landers Row ‘08) • High Blood Pressure • Elevated heart rate • Muscle tension • Immunosuppressant • Addictions • Medications • Cortisol: Neural Cell Death (Root ‘09; Cunningham-Bussel ‘09) • Who Are You Hurting if You Don’t Forgive?
  • 34. To Not Forgive Is Like Drinking Poison • And Hoping Someone Else Dies Buddah
  • 36. EEG Psyche Grad Students Buddhist Monks
  • 38. Left Prefrontal Cortex Right Prefrontal Cortex Prefrontal Cortex Happiness Anger Fear Disgust
  • 40. Compassion & Empathy (Kluger ’07, Panksepp 2009; Decety ’08; Schulman, Hauser) • Compassion: Recognizing the suffering of others and wishing for that suffering to be alleviated • Empathy: The ability to imagine what someone else might be feeling
  • 42. Health Benefits: Gratitude (Emmons ’03; ‘04; Norville ‘07; McCarty ‘95; Oelklaus ‘08; Danner ‘01; Kern ‘04) • Addiction recovery • Weight management • Reduce pain and headaches • Lower blood pressure • Improve cardiovascular function • Improve longevity • Reduce cortisol
  • 43. Altruism (Andreoni ‘09; Dietin ‘10; Smith ‘09) • Giving without expectation of reward • Put welfare of other’s ahead of their own
  • 44. Relationships • Relationships: Single most important factor responsible for survival (Berscheid ‘07) • Selfishness: Root cause of addiction (Pagano ‘11)
  • 45. Confide: One whom you can be candid without fear of reprisal or stigma • Survey: How many people can you confide in? • 1985: Three (10% only 1) • 2004: Two (25% no one; 25% 1) (McPherson ’06)
  • 46. What Does This Plan Sound Like?
  • 47. Study the Great Religions of the World • Christianity • Judaism • Islam • Buddhism • Hinduism
  • 48. 12 – STEP (Addictions) Positive Psychology (Neurochemisty) Christian Values (Fruits of the Spirit) Higher Power - Faith Belief God - Faith Hope (1-3) Hope Hope Inventory Faults (4,5 10) Strengths & Virtues Self-control Forgiveness (6-9) Forgiveness Peace Meditation – Prayer (11) Compassion/ Empathy Kindness Service (12) Gratitude & Altruism Gentleness & Generosity Support Groups Sponsor Relationships Agape - Love Sobriety Happiness Joy
  • 49. Sensory - Thalamo - Cortical • Relay station: Filters what gets through – Auditory – Visual – Associative – Somatosensory • Gustatory • Touch – Prefrontal Cortex – Motor
  • 50. Thalamus: D2 Receptor Deficiency • ↓Thalamic D2BP (D2 binding potential) – ↓ Filtering – ↑ Cortical excitement – ↑ Creativity • Reduced in (Santosa ‘07) – Addiction – ADHD – Bipolar – Schizophrenia
  • 51. Change: Letting Go • “Change is inevitable; the only sure thing in life is change “ unknown • “Change is inevitable; suffering is optional” Zen Buddhism • “If we don’t change, we don’t grow. If we don’t grow, we are not really living” Gail Sheehy • “Life is pleasant. Death is peaceful. It’s the transition that is troublesome” Isaac Asimov
  • 52. WE DON’T Have to HIT BOTTOM • “We rarely change when life is cool and comfortable; we change when we feel the heat” • “Life is like a bicycle: In order to sat balance you have got to keep moving”
  • 53. • “A turtle doesn’t make progress until it sticks its head out….” • How many psychologist does it take to change a light bulb? • “We change our behavior when the pain of staying the same becomes greater than the pain of changing” (Cloud ‘10; Mesiti ‘06)
  • 54. • “Get over it” • “It’s time to get real” • “Is it working for you” • “Awareness without action is worthless” • “Keep doing what you have always done and you will keep on getting what you have always gotten” Ed Foreman • “Insanity is doing the same thing over and over again and expecting it to come out differently”
  • 55. Choose Your Battles Carefully in the world of public opinion “People judge science by whether or not it agrees with what they believe” “What matters is the results; not how you got their” “Clinical guidelines are consensus based and not evidenced based” “Statistically significant is not always clinically significant”
  • 56. Serenity Prayer (Letting Go) • God, grant me the - • Serenity to accept the things I cannot change, • Courage to change the things I can, • Wisdom to know the difference • Dr. Reinhold Niebuhr
  • 57. Resilience & Cross Addiction • Whack down one addiction or compulsion and another pops up • Resilience: Ability to cope with stress and adversity
  • 58. Recovery • Process rather than an outcome – Give yourself permission to take time to make new neural connections • Journey to rediscover the “True Self” – Overcome problems that stand in your way – Feel Feelings – Reclaim your Gifts and Potentials – Align behavior with personal virtues – Fulfill your purpose in life
  • 59. God's Wheel by Shel Silverstein (Silverstiein ’81) God says to me with kind of a smile, "Hey how would you like to be God awhile And steer the world?" "Okay," says I, "I'll give it a try. Where do I set? How much do I get? What time is lunch? When can I quit?" "Gimme back that wheel," says God, "I don't think you're quite ready yet."