The document discusses advancing business in the pharmaceutical industry globally. It notes the many challenges the industry faces, including decreasing growth rates, increased price consciousness, and new stakeholders influencing decisions. It proposes that fundamentally new sales models, approaches, and practices are needed to address these challenges. Specifically, it suggests a new target segmentation focusing on key stakeholders, a new sales offer tailored to each stakeholder, smaller and more specialized sales teams, and a new training model including scientific and economic knowledge as well as relationship management skills.