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Nanotech 101 For Investors
Tim Harper is a serial entrepreneur and advisor on emerging technologies. He discusses how nanotechnology is having a big impact despite being small in scale. In 3 sentences: Nanotechnology has enabled new materials and applications in various industries over the past 10 years. Synthetic biology combines nanotechnology with biotechnology and could be used to address global challenges through more sustainable solutions. Emerging technologies like nanotechnology and synthetic biology will be as transformative to the 21st century as earlier innovations like polymers and semiconductors were to the 20th century.
Elizabeth casey behaviorism.ppt(x)
Behaviorism is a theory that human and animal behavior can be studied scientifically and predicted/controlled through conditioning. Key figures include Ivan Pavlov who studied classical conditioning in dogs, B.F. Skinner who used operant conditioning on pigeons and believed behavior is shaped by environmental reinforcement/punishment, and Albert Bandura who studied observational learning. In schools, teachers can use positive reinforcement like rewards or negative reinforcement like taking away privileges to shape student behavior according to this theory. Children are viewed as responding to environmental stimuli to learn behaviors.
Assessment Project Management in the Real World - Work Book
This document provides materials from a presentation on managing assessment projects, including discussions of communication styles, team member roles, work breakdown structures, and common challenges and solutions. It includes activities and worksheets to help project teams understand different communication styles and how they interact, in order to work together more effectively. The goal is for project managers to leverage various styles by assigning appropriate roles based on each person's strengths. Understanding team dynamics can help ensure projects are completed successfully.
Heritage places in australia
The document lists and briefly describes several important heritage places in Australia, including the Great Barrier Reef, Uluru and Kutu-Jutu park, the Sydney Opera House, and the Royal Exhibition Building. It concludes by asking if the reader likes these heritage places.
Tablers14
The document lists the names and roles of various trustees ("Tr.") for an organization. It provides the names of over 20 trustees and their corresponding positions, which include Chairman, Vice Chairman, Secretary, Treasurer, and roles related to projects, fellowship, rules, small projects, human resource development, extension, greeting cards, information technology, publicity, and editor.
14team10
The document lists the names and roles of various trustees ("Tr.") for an organization. It provides the names of over 20 trustees and their corresponding positions, which include Chairman, Vice Chairman, Secretary, Treasurer, and roles related to projects, fellowship, rules, small projects, human resource development, extension, greeting cards, information technology, publicity, and honorary trustee.
14team10
The document lists the names and roles of various trustees ("Tr.") for an organization. It provides the names of 18 trustees and their positions, which include Chairman, Vice Chairman, Secretary, Treasurer, and roles overseeing projects, fellowship, rules, small projects, human resource development, extension, greeting cards, information technology, publicity, and being honorary trustees.
900
This document provides information about the Madurai Round Table #14 and Madurai Ladies Circle #8 in India including:
1) A list of presidents of the Madurai Round Table #14 from 1970 to 2007.
2) National positions held by members including National Treasurer, National Fellowship Convenor, and National Presidents.
3) Information about the chartering dates of the Madurai City RT #99 and Madurai City LC #60.
4) Details about current membership numbers, number of meets per year, and awards received like the Southern Star Award and designation as a Golden LMF Table.
Recommended
Nanotech 101 For Investors
Tim Harper is a serial entrepreneur and advisor on emerging technologies. He discusses how nanotechnology is having a big impact despite being small in scale. In 3 sentences: Nanotechnology has enabled new materials and applications in various industries over the past 10 years. Synthetic biology combines nanotechnology with biotechnology and could be used to address global challenges through more sustainable solutions. Emerging technologies like nanotechnology and synthetic biology will be as transformative to the 21st century as earlier innovations like polymers and semiconductors were to the 20th century.
Elizabeth casey behaviorism.ppt(x)
Behaviorism is a theory that human and animal behavior can be studied scientifically and predicted/controlled through conditioning. Key figures include Ivan Pavlov who studied classical conditioning in dogs, B.F. Skinner who used operant conditioning on pigeons and believed behavior is shaped by environmental reinforcement/punishment, and Albert Bandura who studied observational learning. In schools, teachers can use positive reinforcement like rewards or negative reinforcement like taking away privileges to shape student behavior according to this theory. Children are viewed as responding to environmental stimuli to learn behaviors.
Assessment Project Management in the Real World - Work Book
This document provides materials from a presentation on managing assessment projects, including discussions of communication styles, team member roles, work breakdown structures, and common challenges and solutions. It includes activities and worksheets to help project teams understand different communication styles and how they interact, in order to work together more effectively. The goal is for project managers to leverage various styles by assigning appropriate roles based on each person's strengths. Understanding team dynamics can help ensure projects are completed successfully.
Heritage places in australia
The document lists and briefly describes several important heritage places in Australia, including the Great Barrier Reef, Uluru and Kutu-Jutu park, the Sydney Opera House, and the Royal Exhibition Building. It concludes by asking if the reader likes these heritage places.
Tablers14
The document lists the names and roles of various trustees ("Tr.") for an organization. It provides the names of over 20 trustees and their corresponding positions, which include Chairman, Vice Chairman, Secretary, Treasurer, and roles related to projects, fellowship, rules, small projects, human resource development, extension, greeting cards, information technology, publicity, and editor.
14team10
The document lists the names and roles of various trustees ("Tr.") for an organization. It provides the names of over 20 trustees and their corresponding positions, which include Chairman, Vice Chairman, Secretary, Treasurer, and roles related to projects, fellowship, rules, small projects, human resource development, extension, greeting cards, information technology, publicity, and honorary trustee.
14team10
The document lists the names and roles of various trustees ("Tr.") for an organization. It provides the names of 18 trustees and their positions, which include Chairman, Vice Chairman, Secretary, Treasurer, and roles overseeing projects, fellowship, rules, small projects, human resource development, extension, greeting cards, information technology, publicity, and being honorary trustees.
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This document provides information about the Madurai Round Table #14 and Madurai Ladies Circle #8 in India including:
1) A list of presidents of the Madurai Round Table #14 from 1970 to 2007.
2) National positions held by members including National Treasurer, National Fellowship Convenor, and National Presidents.
3) Information about the chartering dates of the Madurai City RT #99 and Madurai City LC #60.
4) Details about current membership numbers, number of meets per year, and awards received like the Southern Star Award and designation as a Golden LMF Table.
14team08
This document lists the names and roles of various trustees and positions for an organization. Tr. Riaz Ahmed is listed as the Chairman, with Tr. Promod Joseph as Vice Chairman. Tr. Sridhar SR is the Secretary and Tr. Dr. Satish Devadoss is the Treasurer. It also lists trustees responsible for various projects, fellowship, publicity, human resource development, fundraising, and other roles.
Mrt 14 Ac Visit 08
Madurai Round Table #14 had an active year with 11 business meetings and 6 social meetings. They participated in various service projects for RTI Week and had many fellowship and social events including a dance competition and cricket match with another table. The table also grew their membership and planned fundraising events for the coming year under the leadership of Chairman Tr. Riaz Ahmed.
Tabling
Tabling is a non-political organization that offers professional networking opportunities for men ages 21-40. It aims to develop fellowship through business connections and community service activities while promoting civic responsibility and international understanding. Tabling began in India in 1957 and has grown to around 200 local clubs called Tables with approximately 2350 members. Tables meet regularly and are organized into Areas and governed nationally by Round Table India. The movement supports projects and leadership development through annual dues and fundraising efforts.
The Round Table School
Round Table School provides education to children in a Bangalore slum. Established in 1986 with 1 classroom and 40 students, it now has 20 classrooms, 18 teachers, and 650 students. The school achieves high pass rates on state exams and wins sports competitions. It provides free mid-day meals with an annual budget of Rs. 8 lakhs funded entirely by donations. Challenges include sustaining free education and meals with rising costs and low teacher salaries causing attrition. Donations are requested to support classroom adoption, child sponsorship, and teacher salaries.
77 At Abba Concert
The document discusses a party where kids loved some people or things that were considered the best. A couple sat at a table with their dog Frida and enjoyed the party. At some point, Sandeep was left alone with "them" which concerned one person, while another asked if their younger son was around. The document expresses love for someone named Abba and mentions that the group did finally leave whoever alone to enjoy the party.
X Factor
The document summarizes an event hosted by CPRT 34 and CPSLC 46 on November 17th, 2007 at 6pm at Haldiram Food Court. It was an Area IV event with talent competitions, performances by Twinklers, and awards for Most Popular Tabler, Circler, and Mr. and Mrs. Charming. There was a large turnout of Tablers, Circlers, and Twinklers for the successful event which featured dancing, singing, poetry, and other performances judged by celebrity guests.
Friendshipbingo
The National Fellowship Convenors announce that Area Mid Term Meets will be taking place soon. As part of a National Fellowship Initiative, the best Fellowship Couple from each Area will be honored and hosted by a different Area. The top Fellowship Couples from each Area and the meeting schedules are provided, with locations including Mahabaleswar, Hyderabad, Barielly, Mysore, New Delhi, Bhubaneswar, Nasik, and Yercaud over the dates of January 26-27, February 9-10, 16-17 and 23-24.
Peacock South
This 12-day tour of South India visits several iconic locations, starting in Kochi and ending in Goa. The itinerary includes experiencing Kathakali dance in Kochi, exploring historic sites in Cochin, wildlife viewing at Periyar Tiger Reserve and Mudumalai Sanctuary, cruising the backwaters of Alleppey, visiting hill stations in Ooty and Coimbatore, sightseeing highlights of Mysore like the palace and temples, and ending the trip with beaches and sights in Goa. The package costs $999 per person and includes accommodation, breakfast, some meals, transportation and sightseeing activities.
Cprt34
The document summarizes a fundraiser and publicity event held by Calcutta Park Street Round Table #34 on December 15, 2007 at the Taj Bengal hotel. The event featured a talk by Arindam Chaudhuri and gained publicity through a newspaper advertisement, emails sent to over 5,000 people, and brochures sent to over 1,000 people. Over 300 people attended the event, where an informational film about Round Table India was shown. Several corporate sponsors participated. The event generated further publicity through a post-event newspaper article on December 16, 2007.
RT GC team
The greeting cards team thanks supporters for purchasing RTI greeting cards during Diwali and provides information about card designs on their website. Purchasing the cards helps educate underprivileged children as proceeds go towards the Freedom Through Education project, which has constructed over 1000 schools costing over Rs. 700 million and benefiting more than 600,000 children over 8 years. Supporters are requested to continue purchasing cards during Christmas, New Year, and Pongal.
MKRT 181
MKRT-181's student magazine published a story called "Knights Tai(l)e" written by the magazine editor HAMIR SAMPAT during the 2007-2008 school year. The magazine focused on stories and articles relevant to the students of MKRT-181 during that time period.
Cprt34
On September 2nd, a group of 50 people had a fun day splashing in the water at WOW water park, which included jumbo slides, a lazy river, and river caves. After a tiring but refreshing morning in the water beating the summer heat, the group went to Abcus restaurant for a long lunch session. A photo was taken of the WOW splashing gang, organized by fellowship convenors Manish, Harmeet, Vishu, and Daman.
Metupatti School Project
An inspection was conducted of new tables and benches installed at the Metupatti School in Tamil Nadu, India. The inspection was led by the local Panchayat president and a doctor, and found that the new furniture could comfortably seat 240 students total. The principal welcomed the inspection team from MRT 14, who were providing the new school furniture as part of their philanthropic work through their movement and organization called FTE.
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptx
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We’re talking about Vedic Meditation, a form of meditation that has been around for at least 5,000 years. Back then, the people who lived in the Indus Valley, now known as India and Pakistan, practised meditation as a fundamental part of daily life. This knowledge that has given us yoga and Ayurveda, was known as Veda, hence the name Vedic. And though there are some written records, the practice has been passed down verbally from generation to generation.Cervical Disc Arthroplasty ORSI 2024.pptx
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Ageing, the Elderly, Gerontology and Public Health
Challenges associated with ageing from a public health perspective
Travel Clinic Cardiff: Health Advice for International Travelers
Travel Clinic Cardiff offers comprehensive travel health services, including vaccinations, travel advice, and preventive care for international travelers. Our expert team ensures you are well-prepared and protected for your journey, providing personalized consultations tailored to your destination. Conveniently located in Cardiff, we help you travel with confidence and peace of mind. Visit us: www.nxhealthcare.co.uk
What are the different types of Dental implants.
Are you looking for a long-lasting solution to your missing tooth?
Dental implants are the most common type of method for replacing the missing tooth. Unlike dentures or bridges, implants are surgically placed in the jawbone. In layman’s terms, a dental implant is similar to the natural root of the tooth. It offers a stable foundation for the artificial tooth giving it the look, feel, and function similar to the natural tooth.
Promoting Wellbeing - Applied Social Psychology - Psychology SuperNotes
A proprietary approach developed by bringing together the best of learning theories from Psychology, design principles from the world of visualization, and pedagogical methods from over a decade of training experience, that enables you to: Learn better, faster!
10 Benefits an EPCR Software should Bring to EMS Organizations
The benefits of an ePCR solution should extend to the whole EMS organization, not just certain groups of people or certain departments. It should provide more than just a form for entering and a database for storing information. It should also include a workflow of how information is communicated, used and stored across the entire organization.
Breast cancer: Post menopausal endocrine therapy
Breast cancer in postmenopausal women with hormone receptor-positive (HR+) status is a common and complex condition that necessitates a multifaceted approach to management. HR+ breast cancer means that the cancer cells grow in response to hormones such as estrogen and progesterone. This subtype is prevalent among postmenopausal women and typically exhibits a more indolent course compared to other forms of breast cancer, which allows for a variety of treatment options.
Diagnosis and Staging
The diagnosis of HR+ breast cancer begins with clinical evaluation, imaging, and biopsy. Imaging modalities such as mammography, ultrasound, and MRI help in assessing the extent of the disease. Histopathological examination and immunohistochemical staining of the biopsy sample confirm the diagnosis and hormone receptor status by identifying the presence of estrogen receptors (ER) and progesterone receptors (PR) on the tumor cells.
Staging involves determining the size of the tumor (T), the involvement of regional lymph nodes (N), and the presence of distant metastasis (M). The American Joint Committee on Cancer (AJCC) staging system is commonly used. Accurate staging is critical as it guides treatment decisions.
Treatment Options
Endocrine Therapy
Endocrine therapy is the cornerstone of treatment for HR+ breast cancer in postmenopausal women. The primary goal is to reduce the levels of estrogen or block its effects on cancer cells. Commonly used agents include:
Selective Estrogen Receptor Modulators (SERMs): Tamoxifen is a SERM that binds to estrogen receptors, blocking estrogen from stimulating breast cancer cells. It is effective but may have side effects such as increased risk of endometrial cancer and thromboembolic events.
Aromatase Inhibitors (AIs): These drugs, including anastrozole, letrozole, and exemestane, lower estrogen levels by inhibiting the aromatase enzyme, which converts androgens to estrogen in peripheral tissues. AIs are generally preferred in postmenopausal women due to their efficacy and safety profile compared to tamoxifen.
Selective Estrogen Receptor Downregulators (SERDs): Fulvestrant is a SERD that degrades estrogen receptors and is used in cases where resistance to other endocrine therapies develops.
Combination Therapies
Combining endocrine therapy with other treatments enhances efficacy. Examples include:
Endocrine Therapy with CDK4/6 Inhibitors: Palbociclib, ribociclib, and abemaciclib are CDK4/6 inhibitors that, when combined with endocrine therapy, significantly improve progression-free survival in advanced HR+ breast cancer.
Endocrine Therapy with mTOR Inhibitors: Everolimus, an mTOR inhibitor, can be added to endocrine therapy for patients who have developed resistance to aromatase inhibitors.
Chemotherapy
Chemotherapy is generally reserved for patients with high-risk features, such as large tumor size, high-grade histology, or extensive lymph node involvement. Regimens often include anthracyclines and taxanes.
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14team08
This document lists the names and roles of various trustees and positions for an organization. Tr. Riaz Ahmed is listed as the Chairman, with Tr. Promod Joseph as Vice Chairman. Tr. Sridhar SR is the Secretary and Tr. Dr. Satish Devadoss is the Treasurer. It also lists trustees responsible for various projects, fellowship, publicity, human resource development, fundraising, and other roles.
Mrt 14 Ac Visit 08
Madurai Round Table #14 had an active year with 11 business meetings and 6 social meetings. They participated in various service projects for RTI Week and had many fellowship and social events including a dance competition and cricket match with another table. The table also grew their membership and planned fundraising events for the coming year under the leadership of Chairman Tr. Riaz Ahmed.
Tabling
Tabling is a non-political organization that offers professional networking opportunities for men ages 21-40. It aims to develop fellowship through business connections and community service activities while promoting civic responsibility and international understanding. Tabling began in India in 1957 and has grown to around 200 local clubs called Tables with approximately 2350 members. Tables meet regularly and are organized into Areas and governed nationally by Round Table India. The movement supports projects and leadership development through annual dues and fundraising efforts.
The Round Table School
Round Table School provides education to children in a Bangalore slum. Established in 1986 with 1 classroom and 40 students, it now has 20 classrooms, 18 teachers, and 650 students. The school achieves high pass rates on state exams and wins sports competitions. It provides free mid-day meals with an annual budget of Rs. 8 lakhs funded entirely by donations. Challenges include sustaining free education and meals with rising costs and low teacher salaries causing attrition. Donations are requested to support classroom adoption, child sponsorship, and teacher salaries.
77 At Abba Concert
The document discusses a party where kids loved some people or things that were considered the best. A couple sat at a table with their dog Frida and enjoyed the party. At some point, Sandeep was left alone with "them" which concerned one person, while another asked if their younger son was around. The document expresses love for someone named Abba and mentions that the group did finally leave whoever alone to enjoy the party.
X Factor
The document summarizes an event hosted by CPRT 34 and CPSLC 46 on November 17th, 2007 at 6pm at Haldiram Food Court. It was an Area IV event with talent competitions, performances by Twinklers, and awards for Most Popular Tabler, Circler, and Mr. and Mrs. Charming. There was a large turnout of Tablers, Circlers, and Twinklers for the successful event which featured dancing, singing, poetry, and other performances judged by celebrity guests.
Friendshipbingo
The National Fellowship Convenors announce that Area Mid Term Meets will be taking place soon. As part of a National Fellowship Initiative, the best Fellowship Couple from each Area will be honored and hosted by a different Area. The top Fellowship Couples from each Area and the meeting schedules are provided, with locations including Mahabaleswar, Hyderabad, Barielly, Mysore, New Delhi, Bhubaneswar, Nasik, and Yercaud over the dates of January 26-27, February 9-10, 16-17 and 23-24.
Peacock South
This 12-day tour of South India visits several iconic locations, starting in Kochi and ending in Goa. The itinerary includes experiencing Kathakali dance in Kochi, exploring historic sites in Cochin, wildlife viewing at Periyar Tiger Reserve and Mudumalai Sanctuary, cruising the backwaters of Alleppey, visiting hill stations in Ooty and Coimbatore, sightseeing highlights of Mysore like the palace and temples, and ending the trip with beaches and sights in Goa. The package costs $999 per person and includes accommodation, breakfast, some meals, transportation and sightseeing activities.
Cprt34
The document summarizes a fundraiser and publicity event held by Calcutta Park Street Round Table #34 on December 15, 2007 at the Taj Bengal hotel. The event featured a talk by Arindam Chaudhuri and gained publicity through a newspaper advertisement, emails sent to over 5,000 people, and brochures sent to over 1,000 people. Over 300 people attended the event, where an informational film about Round Table India was shown. Several corporate sponsors participated. The event generated further publicity through a post-event newspaper article on December 16, 2007.
RT GC team
The greeting cards team thanks supporters for purchasing RTI greeting cards during Diwali and provides information about card designs on their website. Purchasing the cards helps educate underprivileged children as proceeds go towards the Freedom Through Education project, which has constructed over 1000 schools costing over Rs. 700 million and benefiting more than 600,000 children over 8 years. Supporters are requested to continue purchasing cards during Christmas, New Year, and Pongal.
MKRT 181
MKRT-181's student magazine published a story called "Knights Tai(l)e" written by the magazine editor HAMIR SAMPAT during the 2007-2008 school year. The magazine focused on stories and articles relevant to the students of MKRT-181 during that time period.
Cprt34
On September 2nd, a group of 50 people had a fun day splashing in the water at WOW water park, which included jumbo slides, a lazy river, and river caves. After a tiring but refreshing morning in the water beating the summer heat, the group went to Abcus restaurant for a long lunch session. A photo was taken of the WOW splashing gang, organized by fellowship convenors Manish, Harmeet, Vishu, and Daman.
Metupatti School Project
An inspection was conducted of new tables and benches installed at the Metupatti School in Tamil Nadu, India. The inspection was led by the local Panchayat president and a doctor, and found that the new furniture could comfortably seat 240 students total. The principal welcomed the inspection team from MRT 14, who were providing the new school furniture as part of their philanthropic work through their movement and organization called FTE.
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Breast cancer: Post menopausal endocrine therapy
Breast cancer in postmenopausal women with hormone receptor-positive (HR+) status is a common and complex condition that necessitates a multifaceted approach to management. HR+ breast cancer means that the cancer cells grow in response to hormones such as estrogen and progesterone. This subtype is prevalent among postmenopausal women and typically exhibits a more indolent course compared to other forms of breast cancer, which allows for a variety of treatment options.
Diagnosis and Staging
The diagnosis of HR+ breast cancer begins with clinical evaluation, imaging, and biopsy. Imaging modalities such as mammography, ultrasound, and MRI help in assessing the extent of the disease. Histopathological examination and immunohistochemical staining of the biopsy sample confirm the diagnosis and hormone receptor status by identifying the presence of estrogen receptors (ER) and progesterone receptors (PR) on the tumor cells.
Staging involves determining the size of the tumor (T), the involvement of regional lymph nodes (N), and the presence of distant metastasis (M). The American Joint Committee on Cancer (AJCC) staging system is commonly used. Accurate staging is critical as it guides treatment decisions.
Treatment Options
Endocrine Therapy
Endocrine therapy is the cornerstone of treatment for HR+ breast cancer in postmenopausal women. The primary goal is to reduce the levels of estrogen or block its effects on cancer cells. Commonly used agents include:
Selective Estrogen Receptor Modulators (SERMs): Tamoxifen is a SERM that binds to estrogen receptors, blocking estrogen from stimulating breast cancer cells. It is effective but may have side effects such as increased risk of endometrial cancer and thromboembolic events.
Aromatase Inhibitors (AIs): These drugs, including anastrozole, letrozole, and exemestane, lower estrogen levels by inhibiting the aromatase enzyme, which converts androgens to estrogen in peripheral tissues. AIs are generally preferred in postmenopausal women due to their efficacy and safety profile compared to tamoxifen.
Selective Estrogen Receptor Downregulators (SERDs): Fulvestrant is a SERD that degrades estrogen receptors and is used in cases where resistance to other endocrine therapies develops.
Combination Therapies
Combining endocrine therapy with other treatments enhances efficacy. Examples include:
Endocrine Therapy with CDK4/6 Inhibitors: Palbociclib, ribociclib, and abemaciclib are CDK4/6 inhibitors that, when combined with endocrine therapy, significantly improve progression-free survival in advanced HR+ breast cancer.
Endocrine Therapy with mTOR Inhibitors: Everolimus, an mTOR inhibitor, can be added to endocrine therapy for patients who have developed resistance to aromatase inhibitors.
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Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
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