1. The document discusses different types of epileptic seizures including generalized tonic-clonic seizures, absence seizures, myoclonic seizures, simplex partial seizures, and complex partial seizures.
2. It also covers the treatment of epilepsy including common antiepileptic drugs like phenobarbital, carbamazepine, valproic acid, and mechanisms of action like inhibition of sodium and calcium channels or potentiation of GABA.
3. Side effects of antiepileptic drugs are discussed and can include central nervous system effects, allergic reactions, and chronic issues affecting organs or body weight.
Tetracyclines slide contains full information about uses, adverse effect, marketed preparation, precaution, route of drug administration, antimicrobial spectrum, mechanism of action, pharmacokineticks and pharmacodynamics of tetracyclines. This slide is very helpful for pharmacy and pharmacology student for the study about tetracyclines.
MECHANISM OF MALIGNANCY BY DR BASHIR AHMED DAR ASSOCIATE PROFESSOR MEDICINE S...Prof Dr Bashir Ahmed Dar
Malignancy (from Latin male "badly" + -gnus "born") is the tendency of a medical condition, especially tumors, to become progressively worse and to potentially result in death. Malignancy in cancers is characterized by anaplasia, invasiveness, and metastasis.
Malignancy is most familiar as a characterization of cancer. A malignant tumor contrasts with a non-cancerous benign tumor in that a malignancy is not self-limited in its growth, is capable of invading into adjacent tissues, and may be capable of spreading to distant tissues. A benign tumor has none of those properties.
Penicillin is obtained from the fungus Penicillium chrysogenum and contains a beta-lactam ring that provides its antibacterial activity. It works by inhibiting the final step in bacterial cell wall synthesis mediated by transpeptidases, preventing cross-linking of peptidoglycan strands and leading to cell lysis. While penicillin G has a narrow spectrum mostly against gram-positive bacteria, subsequent penicillins were developed with improved spectra, stability, and resistance to beta-lactamases. Their mechanisms of resistance include inactivation by beta-lactamases or modifications of penicillin-binding proteins. Beta-lactamase inhibitors can restore the activity of penicillins against bacteria producing
1. The document discusses different types of epileptic seizures including generalized tonic-clonic seizures, absence seizures, myoclonic seizures, simplex partial seizures, and complex partial seizures.
2. It also covers the treatment of epilepsy including common antiepileptic drugs like phenobarbital, carbamazepine, valproic acid, and mechanisms of action like inhibition of sodium and calcium channels or potentiation of GABA.
3. Side effects of antiepileptic drugs are discussed and can include central nervous system effects, allergic reactions, and chronic issues affecting organs or body weight.
Tetracyclines slide contains full information about uses, adverse effect, marketed preparation, precaution, route of drug administration, antimicrobial spectrum, mechanism of action, pharmacokineticks and pharmacodynamics of tetracyclines. This slide is very helpful for pharmacy and pharmacology student for the study about tetracyclines.
MECHANISM OF MALIGNANCY BY DR BASHIR AHMED DAR ASSOCIATE PROFESSOR MEDICINE S...Prof Dr Bashir Ahmed Dar
Malignancy (from Latin male "badly" + -gnus "born") is the tendency of a medical condition, especially tumors, to become progressively worse and to potentially result in death. Malignancy in cancers is characterized by anaplasia, invasiveness, and metastasis.
Malignancy is most familiar as a characterization of cancer. A malignant tumor contrasts with a non-cancerous benign tumor in that a malignancy is not self-limited in its growth, is capable of invading into adjacent tissues, and may be capable of spreading to distant tissues. A benign tumor has none of those properties.
Penicillin is obtained from the fungus Penicillium chrysogenum and contains a beta-lactam ring that provides its antibacterial activity. It works by inhibiting the final step in bacterial cell wall synthesis mediated by transpeptidases, preventing cross-linking of peptidoglycan strands and leading to cell lysis. While penicillin G has a narrow spectrum mostly against gram-positive bacteria, subsequent penicillins were developed with improved spectra, stability, and resistance to beta-lactamases. Their mechanisms of resistance include inactivation by beta-lactamases or modifications of penicillin-binding proteins. Beta-lactamase inhibitors can restore the activity of penicillins against bacteria producing
MALIGNANCY BY DR BASHIR AHMED DAR ASSOCIATE PROFESSOR MEDICINE SOPORE KASHMIRProf Dr Bashir Ahmed Dar
The term "malignancy" refers to cancerous cells that have the ability to spread to other sites in the body (metastasize) or to invade and destroy tissues. Malignant cells tend to have fast, uncontrolled growth due to changes in their genetic makeup.
Epilepsy: Diagnostics, Medications, Myths and Factsabdul waheed
The document discusses epilepsy, a chronic brain disorder characterized by recurrent seizures. It provides details on the types of seizures, experimental models used to study epilepsy, antiepileptic drugs and their mechanisms of action, diagnostic tools, myths and facts about epilepsy, and references. Epilepsy affects people of all ages worldwide and imbalances in neurotransmitters like glutamate and GABA are believed to underlie seizure mechanisms.
This document discusses sex hormones, including estrogens, progesterone, antiestrogens, and antiprogestins. It provides details on the natural and synthetic forms of estrogens and progesterone, their receptors, mechanisms of action, regulation, and uses. The key points are:
- Estrogens and progesterone are secreted by the ovaries and play important roles in the female reproductive system and other body processes.
- They act through nuclear receptors and genomic/nongenomic signaling pathways to regulate gene expression.
- Selective estrogen receptor modulators (SERMs) can act as agonists or antagonists depending on the tissue.
- Progestins and antiestrogens/antiprogestins are
The human-brain-anatomy-1232300552416209-3Rebwar Latif
This document provides an overview of human brain anatomy, functions, and injury mechanisms. It begins with an in-depth exploration of brain anatomy, describing each region of the brain and its functions. This includes sections on the cerebrum and lobes, cerebellum, brainstem, and more. It then discusses how the brain can be injured through direct impacts or rapid acceleration, such as frontal lobe injuries from blows to the front of the head or diffuse axonal injury from rotational motion. The document provides a comprehensive review of brain structures and the mechanisms that can damage the brain.
Nonsteroidal anti inflammatory drugs (NSAIDS)abdul waheed
NSAIDs work by inhibiting the cyclooxygenase (COX) enzymes, which prevents the formation of prostaglandins. Aspirin is a nonselective COX inhibitor that irreversibly acetylates both COX-1 and COX-2. It has analgesic, antipyretic and anti-inflammatory effects. Common adverse effects include gastrointestinal irritation and bleeding. Aspirin is metabolized to salicylic acid and excreted by the kidneys. It is used to treat fever, pain, and inflammatory conditions like rheumatoid arthritis, but carries risks in children and those with asthma or prior gastrointestinal issues.
This document summarizes different types of new drug applications and reviews processes in the United States, including NDAs, ANDAs, and OTC monographs. It discusses the requirements for NDAs including chemistry, manufacturing, clinical trials, and safety data. ANDAs allow for generic drug approval by referencing an already approved drug. OTC monographs provide standards for active ingredients, doses, and labeling of non-prescription drugs. The review processes for these application types and OTC monographs are also briefly outlined.
The passage discusses the importance of summarization in efficiently conveying key information from lengthy documents or meetings. It notes that effective summaries distill the most critical details into a brief yet informative overview, allowing readers to quickly understand the core topics and conclusions without reviewing the source material in its entirety. Summarization is presented as a useful skill for professionals across industries to help colleagues stay updated on evolving projects and initiatives.
Un hombre se levanta de mal humor y pereza, quejándose de tener que ir a trabajar. Al detenerse en un semáforo, ve a un malabarista sin piernas ni un brazo que recoge dinero para su hermano paralítico, quien pinta con la boca. Esto hace que el hombre se dé cuenta de lo afortunado que es y desde entonces valora más lo que tiene. Agradece a Dios cada día por sus dones.
1) A new microchip technology called MONDEX Smartcard eliminates the need for cash or credit cards by storing financial information under the skin.
2) The rice-sized microchip contains a transponder and battery and can be implanted in the right hand or forehead.
3) Over 1 billion microchips are produced annually by Motorola for global distribution, raising concerns about population monitoring and biblical prophecies of end-times.
O texto lista nomes de atores e atrizes famosos do passado e compara como eles envelheceram com o tempo, sugerindo que o envelhecimento afeta a todos. Termina alertando o leitor para que cuide de si mesmo, pois o tempo também irá afetar sua aparência física.
Sexópolis es un sitio web que explora temas relacionados con el placer y el deseo sexual. Ofrece contenido sobre estas cuestiones de una manera abierta y positiva. El objetivo es fomentar una mayor comprensión y aceptación de la sexualidad humana.
Egyptians lived in villages along the Nile river because the surrounding desert was too hot. The annual floods provided fertile land for farming crops and people built their homes on higher ground to avoid flooding. Farming was done with tools pulled by oxen rather than modern tractors. People kept various livestock and some farmers worked on building projects for the pharaoh after harvests. Housing varied in size with wealthier Egyptians having larger homes with painted walls, while poorer families lived in one-room dwellings. Cleanliness and hygiene were important despite limited bathing facilities. Egyptians enjoyed entertainment like festivals and sports in their leisure time.
Vicente y Nazareth Hernández son un matrimonio español que vive en Madrid. Llevan casados 30 años y tienen dos hijos, Ana de 25 años y Juan de 22 años. La familia disfruta pasar tiempo junta cocinando, viendo películas y viajando durante los fines de semana y vacaciones.
MALIGNANCY BY DR BASHIR AHMED DAR ASSOCIATE PROFESSOR MEDICINE SOPORE KASHMIRProf Dr Bashir Ahmed Dar
The term "malignancy" refers to cancerous cells that have the ability to spread to other sites in the body (metastasize) or to invade and destroy tissues. Malignant cells tend to have fast, uncontrolled growth due to changes in their genetic makeup.
Epilepsy: Diagnostics, Medications, Myths and Factsabdul waheed
The document discusses epilepsy, a chronic brain disorder characterized by recurrent seizures. It provides details on the types of seizures, experimental models used to study epilepsy, antiepileptic drugs and their mechanisms of action, diagnostic tools, myths and facts about epilepsy, and references. Epilepsy affects people of all ages worldwide and imbalances in neurotransmitters like glutamate and GABA are believed to underlie seizure mechanisms.
This document discusses sex hormones, including estrogens, progesterone, antiestrogens, and antiprogestins. It provides details on the natural and synthetic forms of estrogens and progesterone, their receptors, mechanisms of action, regulation, and uses. The key points are:
- Estrogens and progesterone are secreted by the ovaries and play important roles in the female reproductive system and other body processes.
- They act through nuclear receptors and genomic/nongenomic signaling pathways to regulate gene expression.
- Selective estrogen receptor modulators (SERMs) can act as agonists or antagonists depending on the tissue.
- Progestins and antiestrogens/antiprogestins are
The human-brain-anatomy-1232300552416209-3Rebwar Latif
This document provides an overview of human brain anatomy, functions, and injury mechanisms. It begins with an in-depth exploration of brain anatomy, describing each region of the brain and its functions. This includes sections on the cerebrum and lobes, cerebellum, brainstem, and more. It then discusses how the brain can be injured through direct impacts or rapid acceleration, such as frontal lobe injuries from blows to the front of the head or diffuse axonal injury from rotational motion. The document provides a comprehensive review of brain structures and the mechanisms that can damage the brain.
Nonsteroidal anti inflammatory drugs (NSAIDS)abdul waheed
NSAIDs work by inhibiting the cyclooxygenase (COX) enzymes, which prevents the formation of prostaglandins. Aspirin is a nonselective COX inhibitor that irreversibly acetylates both COX-1 and COX-2. It has analgesic, antipyretic and anti-inflammatory effects. Common adverse effects include gastrointestinal irritation and bleeding. Aspirin is metabolized to salicylic acid and excreted by the kidneys. It is used to treat fever, pain, and inflammatory conditions like rheumatoid arthritis, but carries risks in children and those with asthma or prior gastrointestinal issues.
This document summarizes different types of new drug applications and reviews processes in the United States, including NDAs, ANDAs, and OTC monographs. It discusses the requirements for NDAs including chemistry, manufacturing, clinical trials, and safety data. ANDAs allow for generic drug approval by referencing an already approved drug. OTC monographs provide standards for active ingredients, doses, and labeling of non-prescription drugs. The review processes for these application types and OTC monographs are also briefly outlined.
The passage discusses the importance of summarization in efficiently conveying key information from lengthy documents or meetings. It notes that effective summaries distill the most critical details into a brief yet informative overview, allowing readers to quickly understand the core topics and conclusions without reviewing the source material in its entirety. Summarization is presented as a useful skill for professionals across industries to help colleagues stay updated on evolving projects and initiatives.
Un hombre se levanta de mal humor y pereza, quejándose de tener que ir a trabajar. Al detenerse en un semáforo, ve a un malabarista sin piernas ni un brazo que recoge dinero para su hermano paralítico, quien pinta con la boca. Esto hace que el hombre se dé cuenta de lo afortunado que es y desde entonces valora más lo que tiene. Agradece a Dios cada día por sus dones.
1) A new microchip technology called MONDEX Smartcard eliminates the need for cash or credit cards by storing financial information under the skin.
2) The rice-sized microchip contains a transponder and battery and can be implanted in the right hand or forehead.
3) Over 1 billion microchips are produced annually by Motorola for global distribution, raising concerns about population monitoring and biblical prophecies of end-times.
O texto lista nomes de atores e atrizes famosos do passado e compara como eles envelheceram com o tempo, sugerindo que o envelhecimento afeta a todos. Termina alertando o leitor para que cuide de si mesmo, pois o tempo também irá afetar sua aparência física.
Sexópolis es un sitio web que explora temas relacionados con el placer y el deseo sexual. Ofrece contenido sobre estas cuestiones de una manera abierta y positiva. El objetivo es fomentar una mayor comprensión y aceptación de la sexualidad humana.
Egyptians lived in villages along the Nile river because the surrounding desert was too hot. The annual floods provided fertile land for farming crops and people built their homes on higher ground to avoid flooding. Farming was done with tools pulled by oxen rather than modern tractors. People kept various livestock and some farmers worked on building projects for the pharaoh after harvests. Housing varied in size with wealthier Egyptians having larger homes with painted walls, while poorer families lived in one-room dwellings. Cleanliness and hygiene were important despite limited bathing facilities. Egyptians enjoyed entertainment like festivals and sports in their leisure time.
Vicente y Nazareth Hernández son un matrimonio español que vive en Madrid. Llevan casados 30 años y tienen dos hijos, Ana de 25 años y Juan de 22 años. La familia disfruta pasar tiempo junta cocinando, viendo películas y viajando durante los fines de semana y vacaciones.
Transparency International publishes an annual Corruption Perceptions Index that ranks countries based on perceptions of public sector corruption. The 2011 index found that the vast majority of countries scored below 5 on a scale of 0 to 10, with New Zealand, Denmark and Finland ranking the highest and North Korea and Somalia ranking the lowest. Transparency International calls on governments and citizens around the world to work together to improve transparency and accountability.
Dolmabahçe Palace fue el principal centro administrativo del Imperio Otomano y más tarde la residencia presidencial de Mustafa Kemal Atatürk, el fundador de la República de Turquía. Construido a un costo equivalente a 35 toneladas de oro, el palacio de 285 habitaciones es el más grande y suntuoso de los palacios imperiales otomanos, reflejando la influencia europea en el arte y la cultura otomanos.
This document lists the names of several famous actresses from Hollywood's Golden Age, including Marilyn Monroe, Elizabeth Taylor, Greta Garbo, Audrey Hepburn, Katharine Hepburn, Bette Davis, Marlene Dietrich, Vivien Leigh, Lauren Bacall, Rita Hayworth, Ingrid Bergman, and Grace Kelly.
Ghazi al Rassam Cartoons File 2 contains Iraqi cartoons from the 1950s and 1960s. The file features political and social commentary cartoons from Iraq during this era. The cartoons provide insight into Iraqi culture and politics in the mid-20th century.
The document contains multiple photographs of King Faisal II of Iraq from various periods between 1926 and 1952. The photographs show Faisal II with other royal family members and heads of state, including Queen Elizabeth II and Prince Philip of the UK. It also contains brief information about the recovery of photographs and artifacts from Faisal II's palace in Baghdad after it was destroyed.
The document is a collection of images from behind the scenes of famous films and actors from the 1940s through the 1960s. It includes photos of Marilyn Monroe, Cary Grant, Bette Davis, and future president Ronald Reagan on sets together. There are also images of Dean Martin, Shirley MacLaine, and Elvis celebrating a birthday; John Wayne in various films over 40 years; and Sophia Loren admiring or being envious of Jayne Mansfield's cleavage on set. Further photos show directors like Stanley Kubrick, Howard Hawks, and Alfred Hitchcock working with big name actors such as Marlon Brando, Charlton Heston, Rita Hayworth, and Orson Welles.