Rose S, Frye RE, Slattery J, Wynne R, Tippett M, et al. (2014) Oxidative Stress Induces Mitochondrial Dysfunction in a Subset of Autism Lymphoblastoid Cell Lines in a Well-Matched Case Control Cohort. PLoS ONE 9(1):e85436.doi:10.1371/journal.pone.0085436.
Dixie Holdings filed a derivative lawsuit on behalf of Red Dice Holdings against Medical Marijuana, Inc. claiming breach of the Red Dice Operating Agreement. Medical Marijuana filed a petition to compel arbitration based on an arbitration clause in the Operating Agreement. Dixie opposed the petition, arguing the clause did not apply because the suit was derivative. Medical Marijuana replied that the suit was essentially between the two members, and so was subject to arbitration under the agreement. Medical Marijuana also provided context regarding the business disputes between the parties leading up to the litigation.
Presentazione di Lorenzo Tosi - Agrea - sulla batteriosi del kiwi e il suo contenimento per il convegno della Camera di Commercio di Verona del 3 ottobre 2013: "kiwi 2013/2014: stime di produzione e commercializzazione"
Rose S, Frye RE, Slattery J, Wynne R, Tippett M, et al. (2014) Oxidative Stress Induces Mitochondrial Dysfunction in a Subset of Autism Lymphoblastoid Cell Lines in a Well-Matched Case Control Cohort. PLoS ONE 9(1):e85436.doi:10.1371/journal.pone.0085436.
Dixie Holdings filed a derivative lawsuit on behalf of Red Dice Holdings against Medical Marijuana, Inc. claiming breach of the Red Dice Operating Agreement. Medical Marijuana filed a petition to compel arbitration based on an arbitration clause in the Operating Agreement. Dixie opposed the petition, arguing the clause did not apply because the suit was derivative. Medical Marijuana replied that the suit was essentially between the two members, and so was subject to arbitration under the agreement. Medical Marijuana also provided context regarding the business disputes between the parties leading up to the litigation.
Presentazione di Lorenzo Tosi - Agrea - sulla batteriosi del kiwi e il suo contenimento per il convegno della Camera di Commercio di Verona del 3 ottobre 2013: "kiwi 2013/2014: stime di produzione e commercializzazione"
This document summarizes key aspects of tax returns and related processes under the GST law in India. It discusses the requirements for tax invoices and credit/debit notes. Registered taxpayers must file monthly returns by the 20th day of the following month, detailing outward and inward supplies, input tax credit, and tax payable. Returns can be rectified for unintentional errors. There are also provisions for matching of returns between supplier and recipient to verify input tax credit claims. The document outlines other return types like annual and final returns as well as late fees for delayed returns.
Immune system dysregulation is well-recognized in autism and thought to be part of the etiology of this disorder. The endocannabinoid system is a key regulator of the immune system via the cannabinoid receptor type 2 (CB2R) which is highly expressed on macrophages and microglial cells. We have previously published significant differences in peripheral blood mononuclear cell CB2R gene expression in the autism population. The use of the Gc protein-derived Macrophage Activating Factor (GcMAF), an endogenous glycosylated vitamin D binding protein responsible for macrophage cell activation has demonstrated positive effects in the treatment of autistic children. In this current study, we investigated the in vitro effects of GcMAF treatment on the endocannabinoid system gene expression, as well as cellular activation in blood monocyte-derived macrophages (BMDMs) from autistic patients compared to age-matched healthy developing controls.
Conclusions
This study presents the first observations of GcMAF effects on the transcriptionomics of the endocannabinoid system and expression of CB2R protein. These data point to a potential nexus between endocannabinoids, vitamin D and its transporter proteins, and the immune dysregulations observed with autism.
Let's discuss it here. I posted this in the
forum earlier today:
I'm definitely not that happy with the alerts
lately. I understand the reasons they are
being done: trim the paper portfolio, etc, but
let's have a little compassion for all the
underwater stock holders who have
patiently held for a couple months, & just
want now to be able to break even, let
alone make money.
Report privacy problems or identity theft to public.resource.org/privacy or call the IRS Identity Theft Hotline at 1-800-908-4490. The document encourages reporting seeing social security numbers and provides resources for reporting privacy issues or identity theft to protect personal information. It lists a website and phone number for reporting these types of problems.
This document discusses registration requirements under the Goods and Services Tax (GST) regime in India. It provides details on the advantages of registration, who must compulsorily register, provisions for casual and non-resident taxable persons, circumstances for cancellation of registration, and procedures for revocation of cancellation. Key points include that registration is required for legally conducting business and claiming input tax credits, and that most existing taxpayers will be migrated to GSTN without needing fresh registration.
The document provides instructions for registering on the GSTN portal in India. It details the steps to generate provisional login credentials, verify the account, fill out registration forms with business and tax details, upload required documents, and submit the application either by digital signature or normally. The registration process involves completing forms in 8 tabs and uploading 5 documents before final submission.
Manufacture of the Medbox, Avnet Inc. has filed a lawsuit against financial terrorist Alan Brochstein, CFA of 420investor.com and Seekingalpha.com who constantly make false accusations about companies especially in the cannabis industry.
The document discusses input tax credit provisions under the GST law, including definitions, availability, utilization, and reversal of credits. Key points include: input tax credit allows avoiding tax cascading and is credited to an electronic ledger; credits must be claimed within a year and by September filing for the previous fiscal year; availability requires tax invoices, goods/service receipt, tax payment, and return filing; utilization follows a set order of taxes (IGST first, then CGST/SGST); and credits are reversed if goods are partly used for non-business purposes or not received back from job workers on time.
This document summarizes key aspects of tax returns and related processes under the GST law in India. It discusses the requirements for tax invoices and credit/debit notes. Registered taxpayers must file monthly returns by the 20th day of the following month, detailing outward and inward supplies, input tax credit, and tax payable. Returns can be rectified for unintentional errors. There are also provisions for matching of returns between supplier and recipient to verify input tax credit claims. The document outlines other return types like annual and final returns as well as late fees for delayed returns.
Immune system dysregulation is well-recognized in autism and thought to be part of the etiology of this disorder. The endocannabinoid system is a key regulator of the immune system via the cannabinoid receptor type 2 (CB2R) which is highly expressed on macrophages and microglial cells. We have previously published significant differences in peripheral blood mononuclear cell CB2R gene expression in the autism population. The use of the Gc protein-derived Macrophage Activating Factor (GcMAF), an endogenous glycosylated vitamin D binding protein responsible for macrophage cell activation has demonstrated positive effects in the treatment of autistic children. In this current study, we investigated the in vitro effects of GcMAF treatment on the endocannabinoid system gene expression, as well as cellular activation in blood monocyte-derived macrophages (BMDMs) from autistic patients compared to age-matched healthy developing controls.
Conclusions
This study presents the first observations of GcMAF effects on the transcriptionomics of the endocannabinoid system and expression of CB2R protein. These data point to a potential nexus between endocannabinoids, vitamin D and its transporter proteins, and the immune dysregulations observed with autism.
Let's discuss it here. I posted this in the
forum earlier today:
I'm definitely not that happy with the alerts
lately. I understand the reasons they are
being done: trim the paper portfolio, etc, but
let's have a little compassion for all the
underwater stock holders who have
patiently held for a couple months, & just
want now to be able to break even, let
alone make money.
Report privacy problems or identity theft to public.resource.org/privacy or call the IRS Identity Theft Hotline at 1-800-908-4490. The document encourages reporting seeing social security numbers and provides resources for reporting privacy issues or identity theft to protect personal information. It lists a website and phone number for reporting these types of problems.
This document discusses registration requirements under the Goods and Services Tax (GST) regime in India. It provides details on the advantages of registration, who must compulsorily register, provisions for casual and non-resident taxable persons, circumstances for cancellation of registration, and procedures for revocation of cancellation. Key points include that registration is required for legally conducting business and claiming input tax credits, and that most existing taxpayers will be migrated to GSTN without needing fresh registration.
The document provides instructions for registering on the GSTN portal in India. It details the steps to generate provisional login credentials, verify the account, fill out registration forms with business and tax details, upload required documents, and submit the application either by digital signature or normally. The registration process involves completing forms in 8 tabs and uploading 5 documents before final submission.
Manufacture of the Medbox, Avnet Inc. has filed a lawsuit against financial terrorist Alan Brochstein, CFA of 420investor.com and Seekingalpha.com who constantly make false accusations about companies especially in the cannabis industry.
The document discusses input tax credit provisions under the GST law, including definitions, availability, utilization, and reversal of credits. Key points include: input tax credit allows avoiding tax cascading and is credited to an electronic ledger; credits must be claimed within a year and by September filing for the previous fiscal year; availability requires tax invoices, goods/service receipt, tax payment, and return filing; utilization follows a set order of taxes (IGST first, then CGST/SGST); and credits are reversed if goods are partly used for non-business purposes or not received back from job workers on time.