Vasopressors are drugs that raise mean arterial pressure through vasoconstriction, while inotropes enhance cardiac contractility. Some drugs possess both vasopressor and inotropic properties. Vasopressors are recommended when there is a significant drop in systolic blood pressure or mean arterial pressure that leads to end-organ dysfunction due to hypoperfusion.

15. • Vasopressors are class of drugs that elevate
Mean Arterial Pressure (MAP) by inducing
vasoconstriction.
• Inotropes increase cardiac contractility.
• Many drugs have both vasopressor and inotropic
effects.
• Vasopressors are indicated for a decrease of >30
mmHg from baseline systolic blood pressure or
MAP <60 mmHg, when either condition results in
endorgan dysfunction secondary to
hypoperfusion.