The global market for serum-free media was valued at $1,022.4 million in 2021 and is expected to reach $3,920.5 million by 2032, registering a CAGR of 12.73% during the forecast period 2022-2032. The growth in the global serum-free media market is expected to be driven by factors such as the low risk of contamination in the media, rising awareness of media-based diagnostic testing, and significant number of funding for executing research and development.

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`res
Focus on Media Type, End User, and
Region
Analysis and Forecast: 2022-2032
September 2022
Global
Serum-Free
Media
Market
Table of Content

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BIS Research is a leading market intelligence and technology research company. BIS Research publishes in-
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Copyright © 2022 BIS Research Inc.
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Table of Content
Executive Summary ........................................................................ 17
1. Market Overview ...................................................................... 21
1.1 Product Definition............................................................................................22
1.1.1 Inclusion and Exclusion .............................................................................22
1.2 Market Scope ...................................................................................................22
1.2.1 Scope of work..............................................................................................22
1.2.2 Key Questions Answered in Report...........................................................23
1.2.3 Assumptions and Limitations ....................................................................24
1.3 Research Methodology ...................................................................................25
1.3.1 Primary Data Sources .................................................................................26
1.3.2 Secondary Data Sources ............................................................................26
1.3.3 Market Estimation Model ............................................................................27
1.3.4 Criteria for Company Profiling ...................................................................28
1.4 Global Serum-Free Media: Market Overview.................................................29
1.4.1 Introduction .................................................................................................29
1.4.2 Serum-Free Media: Overview .....................................................................29
1.4.3 Types of Cell Culture Media .......................................................................30
1.4.3.1 Serum-Free Media vs. Serum-Based Media.....................................................30
1.5 COVID-19 Impact on Global Serum-Free Media Market................................30
1.6 Global Serum-Free Media Market: Industry Analysis...................................31
1.6.1 Overview ......................................................................................................31
1.6.2 Legal Requirements and Frameworks in the U.S. ....................................31
1.6.3 Legal Requirements and Frameworks in Europe .....................................35
1.7 Patent Landscape............................................................................................37
1.7.1 Patent Analysis (by Country) .....................................................................37
1.7.2 Patent Analysis (by Year) ...........................................................................38
2. Global Serum-Free Media: Market Dynamics ............................. 39
2.1 Overview...........................................................................................................40

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2.2 Impact Analysis ...............................................................................................40
2.2.1 Drivers..........................................................................................................42
2.2.1.1 Low Risk of Contamination as a Demand Driver ..............................................42
2.2.1.2 Launch of innovative products in Serum-Free Media Ecosystem .....................42
2.2.1.3 Low reception cost involving small and medium enterprises in comparison
to animal derived media ...................................................................................43
2.2.2 Restraints.....................................................................................................43
2.2.2.1 Slow Growth Rate in Comparison to Serum-Supplemented Media...................43
2.2.2.2 Requirement of Diverse Cell-Type for Specific Media Formulation...................44
2.2.3 Opportunities...............................................................................................45
2.2.3.1 Regulatory Bodies Across the Globe Encourage the Use of Animal-Free
Media in Biological Products ............................................................................45
2.2.3.2 Extensive Adoption of Serum-Free Media in Biopharmaceutical
Companies.......................................................................................................45
3. Global Serum-Free Media (by Media Type), $Mn, 2021-2032 ...... 46
3.1 Overview...........................................................................................................47
3.2 Common Serum-Free ......................................................................................49
3.3 Xeno-Free .........................................................................................................51
3.4 Chemically-Defined .........................................................................................53
3.5 Animal Component-Free .................................................................................55
3.6 Protein-Free......................................................................................................57
4. Global Serum-Free Media (by End User), $Million, 2021-2032 .... 60
4.1 Overview...........................................................................................................61
4.2 Biopharmaceutical Companies ......................................................................62
4.2.1 Biopharmaceutical Companies, by Media Type........................................63
4.3 Academic and Research Organizations ........................................................64
4.3.1 Academic and Research Organizations, by Media Type..........................65
4.4 Clinical Research Organizations....................................................................66
4.4.1 Clinical Research Organizations, by Media Type .....................................67
4.5 Others ...............................................................................................................68

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4.5.1 Others, by Media Type ................................................................................69
5. Global Serum-Free Media Market (by Region), $Million, 2021-
2032......................................................................................... 70
5.1 Overview...........................................................................................................71
5.2 North America..................................................................................................72
5.2.1 Overview ......................................................................................................72
5.2.2 U.S. ...............................................................................................................74
5.2.3 Canada .........................................................................................................74
5.3 Europe ..............................................................................................................76
5.3.1 Overview ......................................................................................................76
5.3.2 Germany.......................................................................................................78
5.3.3 U.K. ...............................................................................................................79
5.3.4 France...........................................................................................................80
5.3.5 Italy ...............................................................................................................80
5.3.6 Spain.............................................................................................................81
5.3.7 Rest-of-Europe.............................................................................................82
5.4 Asia-Pacific ......................................................................................................83
5.4.1 Overview ......................................................................................................83
5.4.2 China ............................................................................................................85
5.4.3 Japan............................................................................................................85
5.4.4 India..............................................................................................................86
5.4.5 Australia.......................................................................................................87
5.4.6 South Korea .................................................................................................88
5.4.7 Rest-of-Asia-Pacific.....................................................................................89
5.5 Latin America...................................................................................................90
5.5.1 Overview ......................................................................................................90
5.5.2 Brazil.............................................................................................................92
5.5.3 Mexico ..........................................................................................................92
5.5.4 Rest-of-Latin-America.................................................................................93
5.6 Rest-of-the-World ............................................................................................94

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5.6.1 Overview ......................................................................................................94
5.6.2 Middle East and Africa................................................................................95
5.6.3 Others...........................................................................................................96
6. Competitive Landscape ............................................................ 97
6.1 Overview...........................................................................................................98
6.2 Key Developments and Strategies.................................................................99
6.2.1 Business Expansions .................................................................................99
6.2.2 Product Launches and Developments ....................................................101
6.2.3 Mergers and Acquisitions.........................................................................102
6.2.4 Others.........................................................................................................104
6.3 Market Share Analysis (by Company)..........................................................105
6.4 Growth-Share Analysis (by Company) ........................................................106
7. Company Profiles ................................................................... 109
7.1 Overview.........................................................................................................110
7.2 MP BIOMEDICALS. ........................................................................................111
7.2.1 Company Overview ...................................................................................111
7.2.2 Role of MP BIOMEDICALS. in the Global Serum-Free Media Market....111
7.2.3 Key Competitors of the Company............................................................111
7.2.4 Analyst Perspective ..................................................................................112
7.3 Corning Incorporated ....................................................................................113
7.3.1 Company Overview ...................................................................................113
7.3.2 Role of Corning Incorporated in the Global Serum-Free Media
Market.........................................................................................................113
7.3.3 Key Customers of the Company ..............................................................113
7.3.4 Key Competitors of the Company............................................................114
7.3.5 Financials...................................................................................................115
7.3.6 Key Insights about Financial Health of the Company............................117
7.3.7 Analyst Perspectives ................................................................................117
7.4 FUJIFILM Holdings Corporation...................................................................119
7.4.1 Company Overview ...................................................................................119

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7.4.2 Role of FUJIFILM Holdings Corporation in the Global Serum-Free
Media Market..............................................................................................119
7.4.3 Key Competitors of the Company............................................................120
7.4.4 Financials...................................................................................................121
7.4.5 Analyst Perspective ..................................................................................122
7.5 PAN-Biotech...................................................................................................123
7.5.1 Company Overview ...................................................................................123
7.5.2 Role of PAN-Biotech. in the Global Serum-Free Media Market .............123
7.5.3 Key Customers of the Company ..............................................................123
7.5.4 Key Competitors of the Company............................................................123
7.5.5 Analyst Perspective ..................................................................................124
7.6 PromoCell GmbH...........................................................................................125
7.6.1 Company Overview ...................................................................................125
7.6.2 Role of PromoCell GmbH in the Global Serum-Free Media Market.......125
7.6.3 Key Competitors of the Company............................................................125
7.6.4 Analyst Perspective ..................................................................................126
7.7 HiMedia Laboratories ....................................................................................127
7.7.1 Company Overview ...................................................................................127
7.7.2 Role of HiMedia Laboratories in the Global Serum-Free Media
Market.........................................................................................................127
7.7.3 Key Customers of the Company ..............................................................127
7.7.4 Key Competitors of the Company............................................................128
7.7.5 Analyst Perspective ..................................................................................128
7.8 Danaher. .........................................................................................................130
7.8.1 Company Overview ...................................................................................130
7.8.2 Role of Danaher. in the Global Serum-Free Media Market.....................130
7.8.3 Key Competitors of the Company............................................................131
7.8.4 Financials...................................................................................................131
7.8.5 Analyst Perspective ..................................................................................134
7.9 Athena Environmental Sciences, Inc. ..........................................................135

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7.9.1 Company Overview ...................................................................................135
7.9.2 Role of Athena Environmental Sciences, Inc. in the Global Serum-
Free Media Market .....................................................................................135
7.9.3 Key Competitors of the Company............................................................135
7.9.4 Analyst Perspective ..................................................................................136
7.10 Lonza Group AG ............................................................................................137
7.10.1 Company Overview ...................................................................................137
7.10.2 Role of Lonza Group AG in the Global Serum-Free Media Market........137
7.10.3 Key Customers of the Company ..............................................................137
7.10.4 Key Competitors of the Company............................................................138
7.10.5 Financials...................................................................................................138
7.10.6 Analyst Perspective ..................................................................................140
7.11 Merck KgaA....................................................................................................141
7.11.1 Company Overview ...................................................................................141
7.11.2 Role of Merck KGaA in the Global Serum-Free Media Market...............141
7.11.3 Key Customers of the Company ..............................................................141
7.11.4 Key Competitors of the Company............................................................142
7.11.5 Financials...................................................................................................142
7.11.6 Key Insights about Financial Health of the Company............................145
7.11.7 Analyst Perspective ..................................................................................145
7.12 R&D Systems, Inc..........................................................................................146
7.12.1 Company Overview ...................................................................................146
7.12.2 Role of R&D Systems, Inc. in the Global Serum-Free Media Market.....146
7.12.3 Key Customers of the Company ..............................................................146
7.12.4 Key Competitors of the Company............................................................146
7.12.5 Analyst Perspective ..................................................................................147
7.13 Sartorius AG...................................................................................................148
7.13.1 Company Overview ...................................................................................148
7.13.2 Role of Sartorius AG in the Global Serum-Free Media Market ..............148
7.13.3 Key Customers of the Company ..............................................................148

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7.13.4 Key Competitors of the Company............................................................149
7.13.5 Financials...................................................................................................149
7.13.6 Key Insights about Financial Health of the Company............................151
7.13.7 Analyst Perspectives ................................................................................152
7.14 Sino Biological, Inc........................................................................................153
7.14.1 Company Overview ...................................................................................153
7.14.2 Role of Sino Biological, Inc. in the Global Serum-Free Media Market
....................................................................................................................153
7.14.3 Key Customers of the Company ..............................................................153
7.14.4 Key Competitors of the Company............................................................153
7.14.5 Analyst Perspective ..................................................................................154
7.15 STEMCELL Technologies Inc. ......................................................................155
7.15.1 Company Overview ...................................................................................155
7.15.2 Role of STEMCELL Technologies Inc. in the Global Serum-Free
Media Market..............................................................................................155
7.15.3 Key Customers of the Company ..............................................................155
7.15.4 Key Competitors of the Company............................................................155
7.15.5 Analyst Perspective ..................................................................................156
7.16 Thermo Fisher Scientific Inc.........................................................................157
7.16.1 Company Overview ...................................................................................157
7.16.2 Role of Thermo Fisher Scientific Inc. in the Global Serum-Free
Media Market..............................................................................................157
7.16.3 Key Competitors of the Company............................................................157
7.16.4 Financials...................................................................................................158
7.16.5 Key Insights about Financial Health of the Company............................161
7.16.6 Analyst Perspective ..................................................................................161

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List of Figures
Figure 1: Global Serum-Free Media Market, $Million, 2021-2032
Figure 2: Global Serum-Free Media Market (by Media Type), $Million, 2021 and 2032
Figure 3: Global Serum-Free Media Market (by End User), $Million, 2021 and 2032
Figure 4: Global Serum-Free Media Market (by Region), $Million, 2021 and 2032
Figure 5: Global Serum-Free Media Market Overview
Figure 6: Global Serum-Free Media Market: Research Methodology
Figure 7: Primary Research Methodology
Figure 8: Bottom-Up Approach (Segment-Wise Analysis)
Figure 9: Top-Down Approach (Segment-Wise Analysis)
Figure 10: Food and Drug Administration’s Role
Figure 11: Cell and Tissue Culture Supplies and Equipment
Figure 12: European Union (EU) Guidelines for Animal-Derived Media
Figure 13: Country-Wise Analysis of Patents, January 2020-July 2022
Figure 14: Year-Wise Analysis of Patents, January 2020-July 2022
Figure 15: Market Dynamics
Figure 16: Global Serum-Free Media Market (by Media Type)
Figure 17: Global Serum-Free Media Market (by Media Type), $Million, 2021 and 2032
Figure 18: Global Serum-Free Media Market (Common Serum-Free), $Million, 2021-2032
Figure 19: Global Serum-Free Media Market (Xeno-Free), $Million, 2021-2032
Figure 20: Global Serum-Free Media Market (Chemically-Defined), $Million, 2021-2032
Figure 21: Global Serum-Free Media Market (Animal Component-Free), $Million, 2021-2032
Figure 22: Global Serum-Free Media Market (Protein-Free), $Million, 2021-2032
Figure 23: Segmentation of Global Serum-Free Media Market (by End User)
Figure 24: Global Serum-Free Media Market (by End User), $Million, 2021 and 2032
Figure 25: Global Serum-Free Media Market (Biopharmaceutical Companies), $Million, 2021-2032
Figure 26: Global Serum-Free Media Market (Biopharmaceutical Companies, by Media Type), $Million,
2021 and 2032
Figure 27: Global Serum-Free Media Market (Academic Research Organization), $Million, 2021-2032
Figure 28: Global Serum-Free Media Market (Academic Research Organizations, by Media Type),
$Million, 2021 and 2032
Figure 29: Global Serum-Free Media Market (Clinical Research Organizations), $Million, 2021-2032

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Figure 30: Global Serum-Free Media Market (Clinical Research Organizations, by Media Type), $Million,
2021 and 2032
Figure 31: Global Serum-Free Media Market (Others), $Million, 2021-2032
Figure 32: Global Serum-Free Media Market (Others, by Media Type), $Million, 2021 and 2032
Figure 33: Global Serum-Free Media Market Share Overview (by Region)
Figure 34: North America Serum-Free Media Market, $Million, 2021-2032
Figure 35: North America: Market Dynamics
Figure 36: North America Serum-Free Media Market (by Country), $Million, 2021 and 2032
Figure 37: U.S. Serum-Free Media Market, $Million, 2021-2032
Figure 38: Canada Serum-Free Media Market, $Million, 2021-2032
Figure 39: Europe Serum-Free Media Market, $Million, 2021-2032
Figure 40: Europe: Market Dynamics
Figure 41: Europe Serum-Free Media Market (by Country), $Million, 2021 and 2032
Figure 42: Germany Serum-Free Media Market, $Million, 2021-2032
Figure 43: U.K. Serum-Free Media Market, $Million, 2021-2032
Figure 44: France Serum-Free Media Market, $Million, 2021-2032
Figure 45: Italy Serum-Free Media Market, $Million, 2021-2032
Figure 46: Spain Serum-Free Media Market, $Million, 2021-2032
Figure 47: Rest-of-Europe Serum-Free Media Market, $Million, 2021-2032
Figure 48: Asia-Pacific Serum-Free Media Market, $Million, 2021-2032
Figure 49: Asia-Pacific: Market Dynamics
Figure 50: Asia-Pacific Serum-Free Media Market (by Country), $Million, 2021 and 2032
Figure 51: China Serum-Free Media Market, $Million, 2021-2032
Figure 52: Japan Serum-Free Media Market, $Million, 2021-2032
Figure 53: India Serum-Free Media Market, $Million, 2021-2032
Figure 54: Australia Serum-Free Media Market, $Million, 2021-2032
Figure 55: South Korea Serum-Free Media Market, $Million, 2021-2032
Figure 56: Rest-of-Asia-Pacific Serum-Free Media Market, $Million, 2021-2032
Figure 57: Latin America Serum-Free Media Market, $Million, 2021-2032
Figure 58: Latin America: Market Dynamics
Figure 59: Latin America Serum-Free Media Market (by Country), $Million, 2021-2032
Figure 60: Brazil Serum-Free Media Market, $Million, 2021-2032
Figure 61: Mexico Serum-Free Market, $Million, 2021-2032

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Figure 62: Rest-of-Latin America Serum-Free Media Market, $Million, 2021-2032
Figure 63: Rest-of-the-World Serum-Free Media Market, $Million, 2021-2032
Figure 64: Rest-of-the-World Serum-Free Media Market (by Region), $Million, 2021-2032
Figure 65: Middle East and Africa Serum-Free Media Market, $Million, 2021-2032
Figure 66: Others Serum-Free Media Market, $Million, 2021-2032
Figure 67: Competitive Landscape (January 2019-June 2022)
Figure 68: Share of Key Developments and Strategies, January 2019-August 2022
Figure 69: Business Expansions (by Company), January 2019-August 2022
Figure 70: Product Launches and Developments (by Company), January 2019-June 2022
Figure 71: Mergers and Acquisitions (by Company), January 2019-August 2022
Figure 72: Others (by Company), January 2019-June 2022
Figure 73: Market Share Analysis of Global Serum-Free Media Market (by Company), 2020 and 2021
Figure 74: Growth-Share Analysis for Global Serum-Free Media (by Company), 2021
Figure 75: Total Number of Companies Profiled
Figure 76: MP BIOMEDICALS.: Product Portfolio for Global Serum-Free Media Market
Figure 77: Corning Incorporated: Product Portfolio for Global Serum-Free Media Market
Figure 78: Corning Incorporated: Overall Financials, $Million, 2019-2021
Figure 79: Corning Incorporated: Revenue (by Segment), $Million, 2019-2021
Figure 80: Corning Incorporated: Revenue (by Region), $Million, 2019-2021
Figure 81: Corning Incorporated: R&D Expenditure, $Million, 2019-2021
Figure 82: FUJIFILM Holdings Corporation: Product Portfolio for Global Serum-Free Media Market
Figure 83: FUJIFILM Holdings Corporation: Overall Financials, $Million, 2019-2021
Figure 84: FUJIFILM Holdings Corporation: Revenue (by Segment), $Million, 2019-2021
Figure 85: PAN-Biotech.: Product Portfolio for Global Serum-Free Media Market
Figure 86: PromoCell GmbH: Product Portfolio for Global Serum-Free Media Market
Figure 87: HiMedia Laboratories: Product Portfolio for Global Serum-Free Media Market
Figure 88: Danaher.: Product Portfolio for Global Serum-Free Media Market
Figure 89: Danaher.: Overall Financials, $Million, 2019-2021
Figure 90: Danaher.: Revenue (by Segment), $Million, 2019-2021
Figure 91: Danaher.: Revenue (by Region), $Million, 2019-2021
Figure 92: Danaher.: R&D Expenditure, $Million, 2019-2021
Figure 93: Athena Environmental Sciences, Inc.: Product Portfolio for Global Serum-Free Media Market
Figure 94: Lonza Group AG: Product Portfolio for Global Serum-Free Media Market

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Figure 95: Lonza Group AG: Overall Financials, $Million, 2019-2021
Figure 96: Lonza Group AG: Revenue (by Segment), $Million, 2019-2021
Figure 97: Merck KGaA: Product Portfolio for Global Serum-Free Media Market
Figure 98: Merck KGaA: Overall Financials, $Million, 2019-2021
Figure 99: Merck KGaA: Revenue (by Segment), $Million, 2019-2021
Figure 100: Merck KGaA: Revenue (by Region), $Million, 2019-2021
Figure 101: Merck KGaA: R&D Expenditure, $Million, 2019-2021
Figure 102: R&D Systems, Inc.: Product Portfolio for Global Serum-Free Media Market
Figure 103: Sartorius AG: Product Portfolio for Global Serum-Free Media Market
Figure 104: Sartorius AG: Overall Financials, $Million, 2019-2021
Figure 105: Sartorius AG: Revenue (by Segment), $Million, 2019-2021
Figure 106: Sartorius AG: Revenue (by Region), $Million, 2019-2021
Figure 107: Sartorius AG: R&D Expenditure, $Million, 2019-2021
Figure 108: Sino Biological, Inc.: Product Portfolio for Global Serum-Free Media Market
Figure 109: STEMCELL Technologies Inc.: Product Portfolio for Global Serum-Free Media Market
Figure 110: Thermo Fisher Scientific Inc.: Product Portfolio for Global Serum-Free Media Market
Figure 111: Thermo Fisher Scientific Inc.: Overall Financials, $Million, 2019-2021
Figure 112: Thermo Fisher Scientific Inc.: Revenue (by Segment), $Million, 2019-2021
Figure 113: Thermo Fisher Scientific Inc.: Revenue (by Region), $Million, 2019-2021
Figure 114: Thermo Fisher Scientific Inc.: R&D Expenditure, $Million, 2019-2021

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List of Tables
Table 1: Likert Scale
Table 2: Impact Analysis of Market Drivers
Table 3: Impact Analysis of Market Restraints
Table 4: Impact Analysis of Market Opportunities
Table 5: Common cell lines and growth media
Table 6: Some Companies Offering Common Serum-Free Media
Table 7: Some Companies Offering Xeno-Free Media
Table 8: Some Companies Offering Chemically-Defined Media
Table 9: Some Companies Offering Animal Component-Free Media
Table 10: Some Companies Offering Protein-Free Media

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