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Seniorsemppt
- 1. What have YOU suffered?
- 2. ANY PART
- 7. PAIN
- 19. the fight for… Survival
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Editor's Notes
- First Slide: describe what Lupus is and explain how it is an autoimmune disease that can attack any part of the body…the healthy cells…In lupus, something goes wrong with your immune system, which is the part of the body that fights off viruses, bacteria, and germs ("foreign invaders," like the flu)
- I chose this topic because…Discuss what thesis is and then follow with findings.
- People with Lupus need many different doctors who work together to treat their illness….most see rheumatologist: joints and muscles, dermatologist: cutaneous lupus for the skin, Nephrologist: kidney problems, Obsterician: Pregnancy…..
- Autoimmune means your immune system cannot tell the difference between these foreign invaders and your body’s healthy tissues ("auto" means "self") and creates autoantibodies that attack and destroy healthy tissue. These autoantibodies cause inflammation, pain, and damage in various parts of the body.
- Systematic lupus erythematosus: muscuoloskeletal system: kidneys, remove waste from our blood, inflammation of the nervous system and the brain, lasting effects, cause memory problems confusion, headaches and strokes
- One of the major symptoms of lupus is PAIN. It can come from any of the diseases that lupus causes. One of the major causes of pain in lupus is patients in inflammation in various parts of the body. This inflammation can come from arthritis
- Arthritis is one of the most common secondary diseases that comes along with lupus. It causes inflammation in the joints and bones and causes stiffness. It can affect, but is not limited to, fingers, toes, arms, feet and legs. This can be extremely uncomfortable for patients.
- There are many different ways to treat inflammation. There is actually a category of medication called anti-inflammatories. Even though these medications give relief to patients, they can cause some serious side effects. There is more than one category for anti-inflammatories; non-steroidal and steroidal.
- A few non-steroidal anti-inflammatories include tylenol, aleve, motrin, advil, and celebraex. Aleve, advil and motrin are over the counter and non-perscription and are also not expensive. But, these come with side affects. Asprin can cause stomach problems, tylenol can affect the liver and all of these can cause stomach irratation and gastrointestinal problems. All of these medications are used to treat other illnesses and were not made specifically to treat lupus.
- Steroidal anti-inflammatories are nothing like the steroids that athletes may take for body building or strength. In addition to treating inflammation, it will help regulate blood pressure and the immune system. These are called corticosteroids. They decrease swelling, warmth, tenderness and pain. Different from non-steroidals, the can be taken through cream, IV or be injected directly into the muscle. The most common of these is prednisone This medication is also taken for many other diseases. Common side effects are acne, weight gain, fluid retention, easy bruising and other side affects that can last a lifetime.
- Another type of steroid is called DHEA which as been used in recent clinical trials. It was originally a treatment for cancer, but is now being used for lupus patients. It was available over the counter and was once used as an anti-ager, a sexual enhancer and a cancer preventative. It can help women with an estrogen/testosterone imbalance, which is commonly found in lupus. Because lupus affects hormones, it can give the risk of gender based cancers. This medication balances the hormones to prevent that.
- Since lupus patients can suffer serious side affects from meds such as anti-inflams, they might need a medication to help them lower the doses. This type of medication is called antimalarials. There are no antimalarials created specificially for the treatment of lupus. They can also descreaseblod clotting and autoantibody production. These drugs take more time to work than anti-inflammatories. Two examples of antimalarials are Plaquenil and Aralen. They do not cause many side affects but in few cases, it causes retina damage.
- Some other medications which were originally made for other diseases are immunosupressives. These medications are also used to lower steroid dosage, but they make the immune system very very low. Even the smallest cut can be very serious. Cytonax and Rheumatrex were originally used to fight cancer. Cytonax is used to help with kidneys and lungs and Rheumatrex is used to treat arthritis. Another med is Imuran which also helps lower steroid dosage and control the lungs and kidneys. It was originally made for patients with kidney transplants to help them from rejecting.
- Lupus patients suffer from, eye impairment, failure of the organs, and vasculitis, when traditional treatments fail…CHEMO…after chemotherapy, stemcells
- After chemotherapy, bone marrow stem cells from own blood, develop into healthy immune cells, cells put back into bone marrow, form functioning imune system, since genes do not predetermine disease, they don’t develop into dangerous autoimmune cells
- Wrap up presentation…discuss a little bit about survival…recap