The document outlines the agenda for Science Day 2021, which will include discussions of the 2021 Nobel Prizes in Physiology or Medicine, Physics, Chemistry, Literature, Peace, and Economics. The day-long event will begin with an introduction and overview of the Nobel Prizes awarded in 2021, followed by sessions on SARS-CoV-2 variants and vaccines, the 100th anniversary of insulin, and breakthroughs in science in 2021. It will conclude with a question and answer period.
Science Day 2020 for K-12 Students by Govinda BhisettiGovinda Bhisetti
The presentation made at Science Day 2020 for school children on December 30, 2020. It covers 2020 Nobel prizes, Science of COVID-19 and Vaccines Development and Science Breakthroughs of the Year 2020.
The best job in the world: practicing public health, past present and futureJohn Middleton
Practicing public health, past present and future. annual lecture to the Maastricht Global Public Health Leadership students course. with an extended additional section on the year 2020 in pandemic and lessons 201211 middletonj maaastricht
Slides presented by David Wood, chair of London Futurists and Principal of Delta Wisdom, at the Funzing event at Café 1001, Brick Lane, on 26th June 2017: http://uk.funzing.com/funz/ldn-talks-night-is-tech-the-end-of-getting-old-9331
The document outlines Dr. Darshna Sarvaiya's presentation on tuberculosis (TB). The objectives of the presentation are to discuss the history and milestones of TB, the global and Indian burden of TB, the natural history and epidemiology of the disease, and interventions for TB control up to diagnosis. Key points include that TB is caused by mycobacteria and affects the lungs in most cases. India accounts for a quarter of global TB cases. Control measures aim to reduce prevalence and incidence through early detection and treatment of active cases.
Child and Family Impacts of the Coronavirus Syndemic: Developmental, Family, ...Université de Montréal
My presentation is part of the WASP-WPA Interorganizational Symposium for the WPA 21st Virtual World Congress of Psychiatry, Catragena, Colombia, October 16-21, 2021
Session Description
At this time, the death toll from COVID-19 is approaching 3 million people worldwide. The full toll of COVID-19 far exceeds
even this sobering number. Beyond the direct biological impacts of an infectious disease, the global impact of COVID-19 is
revealing and magnifying pre-existing fractures in our social structures. COVID-19 has led to significant differential impacts
among groups across age, health and socio-cultural variables, whether through increased direct illness morbidity and
mortality in the elderly or those with mental illness, or through indirect impacts associated with widespread societal and
health system changes, including youth impacted by confinement and social isolation impinging on development of prosocial
skills, increased caregiver and family stresses ranging from financial distress to violence, and further disenfranchisement of
already marginalized and vulnerable groups. At the same time, heightened public awareness and outcry about such
disparities has the potential to fuel new alliances, challenging and perhaps dismantling some historical stereotypes of race,
ethnicity, gender, sexual orientation, age, disability and illness. Rather than a pandemic, the global impacts reveal a
syndemic – multiple pandemics along different lines, both the viral/biological pandemic, plus a social pandemic superimposed
on pre-existing fault lines of inequity, poverty, mental illness, racism, sexism, ableism, ageism and other forms of stigma and
discrimination. This session will include discussion of the varied impacts of COVID-19 and exploration of their root causes
from a social psychiatry perspective.
Visual Communication of the Environment in Theory and Practice: Nurturing Rel...EcoLabs
Image-makers have the unique ability to make invisible ecological processes and relationships visible, tangible and accessible. Within the context of an increasingly visual culture, images have potential to nurture the development of new perceptual capabilities and encourage relational perception. Graphic design is well suited to facilitate environmental learning since it can draw on a wide variety of visual strategies to display specific geographic spaces, ecological processes, abstract concepts and future scenarios. With design strategies, image-makers can reveal relationships, patterns and dynamics in complex systems. For these reasons, graphic design has exceptional potential to support relational perceptual practices and ecological literacy.
Science Day 2020 for K-12 Students by Govinda BhisettiGovinda Bhisetti
The presentation made at Science Day 2020 for school children on December 30, 2020. It covers 2020 Nobel prizes, Science of COVID-19 and Vaccines Development and Science Breakthroughs of the Year 2020.
The best job in the world: practicing public health, past present and futureJohn Middleton
Practicing public health, past present and future. annual lecture to the Maastricht Global Public Health Leadership students course. with an extended additional section on the year 2020 in pandemic and lessons 201211 middletonj maaastricht
Slides presented by David Wood, chair of London Futurists and Principal of Delta Wisdom, at the Funzing event at Café 1001, Brick Lane, on 26th June 2017: http://uk.funzing.com/funz/ldn-talks-night-is-tech-the-end-of-getting-old-9331
The document outlines Dr. Darshna Sarvaiya's presentation on tuberculosis (TB). The objectives of the presentation are to discuss the history and milestones of TB, the global and Indian burden of TB, the natural history and epidemiology of the disease, and interventions for TB control up to diagnosis. Key points include that TB is caused by mycobacteria and affects the lungs in most cases. India accounts for a quarter of global TB cases. Control measures aim to reduce prevalence and incidence through early detection and treatment of active cases.
Child and Family Impacts of the Coronavirus Syndemic: Developmental, Family, ...Université de Montréal
My presentation is part of the WASP-WPA Interorganizational Symposium for the WPA 21st Virtual World Congress of Psychiatry, Catragena, Colombia, October 16-21, 2021
Session Description
At this time, the death toll from COVID-19 is approaching 3 million people worldwide. The full toll of COVID-19 far exceeds
even this sobering number. Beyond the direct biological impacts of an infectious disease, the global impact of COVID-19 is
revealing and magnifying pre-existing fractures in our social structures. COVID-19 has led to significant differential impacts
among groups across age, health and socio-cultural variables, whether through increased direct illness morbidity and
mortality in the elderly or those with mental illness, or through indirect impacts associated with widespread societal and
health system changes, including youth impacted by confinement and social isolation impinging on development of prosocial
skills, increased caregiver and family stresses ranging from financial distress to violence, and further disenfranchisement of
already marginalized and vulnerable groups. At the same time, heightened public awareness and outcry about such
disparities has the potential to fuel new alliances, challenging and perhaps dismantling some historical stereotypes of race,
ethnicity, gender, sexual orientation, age, disability and illness. Rather than a pandemic, the global impacts reveal a
syndemic – multiple pandemics along different lines, both the viral/biological pandemic, plus a social pandemic superimposed
on pre-existing fault lines of inequity, poverty, mental illness, racism, sexism, ableism, ageism and other forms of stigma and
discrimination. This session will include discussion of the varied impacts of COVID-19 and exploration of their root causes
from a social psychiatry perspective.
Visual Communication of the Environment in Theory and Practice: Nurturing Rel...EcoLabs
Image-makers have the unique ability to make invisible ecological processes and relationships visible, tangible and accessible. Within the context of an increasingly visual culture, images have potential to nurture the development of new perceptual capabilities and encourage relational perception. Graphic design is well suited to facilitate environmental learning since it can draw on a wide variety of visual strategies to display specific geographic spaces, ecological processes, abstract concepts and future scenarios. With design strategies, image-makers can reveal relationships, patterns and dynamics in complex systems. For these reasons, graphic design has exceptional potential to support relational perceptual practices and ecological literacy.
The document discusses the history and definition of biodiversity. It notes that the term "biodiversity" was coined in 1985 and gained popularity after a 1988 book. The document also summarizes the history and goals of the 1992 Convention on Biological Diversity, which aims to conserve biodiversity and share benefits from genetic resources. It then discusses some key causes and implications of biodiversity loss.
The document outlines the schedule for Science Day 2012 hosted by Govinda Bhisetti on December 28, 2012. The day-long event includes an introduction, a tribute to Dr. Yellapragada SubbaRow, a discussion of the 2012 Nobel Prizes, a screening of a movie, and presentations on breakthroughs in science from the past year. It also provides background information on Dr. SubbaRow and how Nobel Prize winners are selected.
This issue of the Genetics Society News features the following:
- An award was given and meetings are announced.
- The editor welcomes readers to the issue and provides information on submitting items for future issues.
- An overview of the contents includes reports on medals, meetings, students, and travel as well as features on communicating science and the 20th anniversary of Dolly the sheep.
The COVID-19 pandemic has had both positive and negative impacts on ecosystems. Positively, it led to improved air and water quality during lockdowns from reduced pollution. Wildlife flourished with less human activity. However, it also resulted in a massive increase in biomedical waste from healthcare. Discarded masks and plastic PPE have become pervasive pollutants in oceans and landscapes. The surge in online shopping further drove up packaging waste. If medical waste is not properly disposed, it risks spreading infection or new virus variants emerging. The pandemic also suspended recycling in many areas, causing landfills to grow substantially.
6th international day of women and girls in science assembly “Beyond the Borders: Equality in Science for Society” To ask a Question to Panelists, which will be available from 4-9 February 2021; In celebration of the 75th anniversary of the United Nations, the Girls in Science will present their first Progress Report, showcasing their achievements as constructive agents of change, and how Girls in Science all over the world stand up for equality, the rights for health, education, water, sustainable energy, and climate change, among others.
A SHARP RISE IN DEATH TOLL AFTER THE COVID VACCINATION WORLDWIDE !huldahministry
The document discusses the recent spread of a deadly fungal infection among COVID patients in India. It then summarizes an article claiming that widespread COVID vaccination programs have reversed downward death trends and increased mortality rates globally. The article argues this occurred because effective early treatments were discouraged and a rushed global vaccination agenda was implemented instead. It presents graphs purportedly showing correlations between the timing of vaccination programs and spikes in COVID cases and deaths in India and other countries. The document calls this a "terrible criminal global agenda" and says the only recourse is prayer for God's vengeance against the wicked.
The document outlines the schedule and topics for Govinda Bhisetti's Science Day event on December 30, 2008. The schedule includes presentations on the 2006 Nobel Prizes, science trivia, a discussion on breakthroughs in science in 2008, and a discussion on the 2008 financial meltdown.
Chahal Academy is one of the best IAS coaching in Bhilai. We have best mentors across India, dedicated to providing the best approach and study material to aspirants willing to prepare for UPSC examination. To know more please visit: https://chahalacademy.com/best-ias-coaching-in-bhilai
The document discusses microbiology in everyday life. It describes how microorganisms can affect the air, water, food and environment. Microbes are spread through the air people breathe, water they drink, food they eat, direct contact and carriers like insects and animals. Various diseases caused by bacteria, viruses and other microbes transmitted through these routes are described. The document also discusses how microbes can spoil food and cause food poisoning or food infections.
How To: Essay Types | Essay writing skills, Essay writing, Essay .... What Is an Essay? Different Types of Essays with Examples • 7ESL. 4 Major types of essays - Infographics. 4 Outstanding Types of Essay Writing Styles – Helpful Guidelines. 4 Essay Types and How to Distinguish Them | Howtowrite.CustomWritings.com. Tips on How to Write Effective Essay and 7 Major Types in 2021 | Types .... A complete Guide for Essay writing. Business paper: Types of essays.
Knowledge, Attitude and Vaccination Status on Covid 19 among Adults Living in...ijtsrd
Introduction In 2019, the whole World faced with the great challenges in the health due to the epic outbreak of novel Corona virus. World Health Organization WHO declared the Corona virus as the global health emergency on January 30, 2020. The Covid 19 vaccine are widely created for their role in reducing the spread of Covid 19 and reducing the severity and death caused by Covid 19. People’s perception toward vaccine acceptance have fluctuated with the information flow in various social medias and the severity of COVID 19 cases. This study aimed to assess the level of knowledge and attitude about Covid 19 vaccine among the community people. Methods Quantitative approach with descriptive research design was adopted for the present study. Two hundred 200 adults aged 20 60 years from Angarpada and Mahul residence in Khordha District, Odisha were selected purposively. Adults who gave their consent and were present during the data collection period were included in the study. Pregnant woman and the people have systemic diseases were excluded from the study. The tools used to collect the data were 1. Socio demographic questionnaire, 2. Knowledge questionnaire to assess the Covid 19 vaccination and 3. Attitude scale to assess the attitude on Covid 19 vaccine. The data was analysed by using descriptive and inferential statistics. Results Vaccination status of the adults living in the Khordha district shows that 83 of people vaccinated for COVID 19. Level of knowledge on covid19 vaccine shows that more than half of the people 52.5 had poor knowledge. Highest percentage of adults 47.5 had neutral attitude. The mean knowledge score is 10±3.59 and mean attitude score is 92.38±6.54. There was a very weak positive correlation r = 0.176, p = 0.096 found between the knowledge and attitude. Conclusion The study results indicates that most of the community people are having adequate knowledge and having neutral attitude towards the Covid 19 vaccination. It shows that awareness is needed on the importance of vaccination. Dr. B. Gomathi | Sreya De | Sutapa Roy | Sandip Pradhan | Ankit Barla | Sayantani Das "Knowledge, Attitude and Vaccination Status on Covid-19 among Adults Living in Selected Rural Areas of Khurdha District, Odisha" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-7 | Issue-5 , October 2023, URL: https://www.ijtsrd.com/papers/ijtsrd59985.pdf Paper Url: https://www.ijtsrd.com/medicine/nursing/59985/knowledge-attitude-and-vaccination-status-on-covid19-among-adults-living-in-selected-rural-areas-of-khurdha-district-odisha/dr-b-gomathi
A paper cover the devised policy for patrons in libraries during covid-19. The author has formulated few policy that are helpful for the entire community based on libraries and educational institute
1. The document discusses strategies for libraries and librarians during the COVID-19 pandemic. It outlines three main strategies: providing public health awareness through research on COVID-19, supporting researchers through access to relevant studies and literature, and fulfilling the research needs of library users remotely.
2. Many libraries closed completely during lockdowns, while others provided only minimal services like curbside pickup. Remote services became important, including providing digital content, online reference services, and education on using e-resources.
3. Librarians helped raise awareness of preventive measures and advise on avoiding misinformation. They supported medical researchers through literature and kept users engaged through online activities, fulfilling research needs remotely through tools like Zoom.
CEO of Infinitum Humanitarian Systems Eric Rasmussen, MD, MDM, FACP helped the Medical Devices Group understand the depth of the challenges to global health.
You really have to watch his talk (some of the images will take your breath away) for the full impact of the presentation and please share it on social media and with your colleagues.
Visit http://medgroup.biz/future-global-health for the video recap and transcript and consider the 10x Medical Device Conference to meet speakers like Eric.
For 10x information, see http://medgroup.biz/About-10x
Emerging Propositions for Science Actions for the UN Food System SummitFrancois Stepman
Presentation by: Joachim von Braun, Chair of the Scientific Group of the UNFSS Expectations of the Scientific Group for the Summit
25 June 2021. The Joint Programming Initiative for Agriculture, Food Security and Climate Change (FACCE-JPI) organised a dedicated workshop for invited participants to contribute to the vision and objectives of the upcoming UN Food Systems Summit (UNFSS).
The document discusses the need for a great transition to achieve planetary health. It states that we must learn to produce, consume, construct our cities, manage our landscapes and resources, and view our relationship with nature very differently. It also notes that 6 out of 9 planetary boundaries have already been breached and that all nations must transform their economic systems to prioritize both human well-being and environmental sustainability. The document advocates for adopting a framework of planetary boundaries and social foundations to guide this necessary global transition to a more sustainable future.
International Conference of Multidisciplinary & Interdisciplinary Bioscience (MIBIO 2022) will provide Biological Sciences Research remains the ubiquitous realm in better human health and well being. Multidisciplinary and interdisciplinary Bioscience Research has been stressed for explicit scientific advancements. Impact publications for a wider outreach are ascertained. MIBIO 2022 represents the launch-pad forum for researchers, biologists, students, Scientists and Physicians in peer-reviewed podium encompassing Biological Sciences. The conference takes pleasure in inviting your peer Research for a fantabulous realm of rapport in the arena of multidisciplinary and interdisciplinary Life sciences. The area offers discussions with biomedical and environment impact assessors. This allows you to enlighten, enrich and rejuvenate the multitude of oneness in biological sciences
International Conference of Multidisciplinary & Interdisciplinary Bioscience ...ijbesjournal
International Conference of Multidisciplinary & Interdisciplinary Bioscience (MIBIO 2022) will provide Biological Sciences Research remains the ubiquitous realm in better human health and well being. Multidisciplinary and interdisciplinary Bioscience Research has been stressed for explicit scientific advancements. Impact publications for a wider outreach are ascertained. MIBIO 2022 represents the launch-pad forum for researchers, biologists, students, Scientists and Physicians in peer-reviewed podium encompassing Biological Sciences
Lecture 12 - Mutualisms and Microbiomes - BIS2C Jonathan Eisen
This document contains slides from a lecture on mutualisms and microbiomes. The lecture discusses different types of mutualistic relationships between organisms, including examples like tubeworms that rely on symbiotic bacteria for nutrients. It also examines the human microbiome and how microbes in our bodies contribute to health. The lecture explores how the microbiome can be disturbed by factors like antibiotics and how restoring balance, such as through fecal transplants, can address issues like C. difficile infections.
The document discusses the history and definition of biodiversity. It notes that the term "biodiversity" was coined in 1985 and gained popularity after a 1988 book. The document also summarizes the history and goals of the 1992 Convention on Biological Diversity, which aims to conserve biodiversity and share benefits from genetic resources. It then discusses some key causes and implications of biodiversity loss.
The document outlines the schedule for Science Day 2012 hosted by Govinda Bhisetti on December 28, 2012. The day-long event includes an introduction, a tribute to Dr. Yellapragada SubbaRow, a discussion of the 2012 Nobel Prizes, a screening of a movie, and presentations on breakthroughs in science from the past year. It also provides background information on Dr. SubbaRow and how Nobel Prize winners are selected.
This issue of the Genetics Society News features the following:
- An award was given and meetings are announced.
- The editor welcomes readers to the issue and provides information on submitting items for future issues.
- An overview of the contents includes reports on medals, meetings, students, and travel as well as features on communicating science and the 20th anniversary of Dolly the sheep.
The COVID-19 pandemic has had both positive and negative impacts on ecosystems. Positively, it led to improved air and water quality during lockdowns from reduced pollution. Wildlife flourished with less human activity. However, it also resulted in a massive increase in biomedical waste from healthcare. Discarded masks and plastic PPE have become pervasive pollutants in oceans and landscapes. The surge in online shopping further drove up packaging waste. If medical waste is not properly disposed, it risks spreading infection or new virus variants emerging. The pandemic also suspended recycling in many areas, causing landfills to grow substantially.
6th international day of women and girls in science assembly “Beyond the Borders: Equality in Science for Society” To ask a Question to Panelists, which will be available from 4-9 February 2021; In celebration of the 75th anniversary of the United Nations, the Girls in Science will present their first Progress Report, showcasing their achievements as constructive agents of change, and how Girls in Science all over the world stand up for equality, the rights for health, education, water, sustainable energy, and climate change, among others.
A SHARP RISE IN DEATH TOLL AFTER THE COVID VACCINATION WORLDWIDE !huldahministry
The document discusses the recent spread of a deadly fungal infection among COVID patients in India. It then summarizes an article claiming that widespread COVID vaccination programs have reversed downward death trends and increased mortality rates globally. The article argues this occurred because effective early treatments were discouraged and a rushed global vaccination agenda was implemented instead. It presents graphs purportedly showing correlations between the timing of vaccination programs and spikes in COVID cases and deaths in India and other countries. The document calls this a "terrible criminal global agenda" and says the only recourse is prayer for God's vengeance against the wicked.
The document outlines the schedule and topics for Govinda Bhisetti's Science Day event on December 30, 2008. The schedule includes presentations on the 2006 Nobel Prizes, science trivia, a discussion on breakthroughs in science in 2008, and a discussion on the 2008 financial meltdown.
Chahal Academy is one of the best IAS coaching in Bhilai. We have best mentors across India, dedicated to providing the best approach and study material to aspirants willing to prepare for UPSC examination. To know more please visit: https://chahalacademy.com/best-ias-coaching-in-bhilai
The document discusses microbiology in everyday life. It describes how microorganisms can affect the air, water, food and environment. Microbes are spread through the air people breathe, water they drink, food they eat, direct contact and carriers like insects and animals. Various diseases caused by bacteria, viruses and other microbes transmitted through these routes are described. The document also discusses how microbes can spoil food and cause food poisoning or food infections.
How To: Essay Types | Essay writing skills, Essay writing, Essay .... What Is an Essay? Different Types of Essays with Examples • 7ESL. 4 Major types of essays - Infographics. 4 Outstanding Types of Essay Writing Styles – Helpful Guidelines. 4 Essay Types and How to Distinguish Them | Howtowrite.CustomWritings.com. Tips on How to Write Effective Essay and 7 Major Types in 2021 | Types .... A complete Guide for Essay writing. Business paper: Types of essays.
Knowledge, Attitude and Vaccination Status on Covid 19 among Adults Living in...ijtsrd
Introduction In 2019, the whole World faced with the great challenges in the health due to the epic outbreak of novel Corona virus. World Health Organization WHO declared the Corona virus as the global health emergency on January 30, 2020. The Covid 19 vaccine are widely created for their role in reducing the spread of Covid 19 and reducing the severity and death caused by Covid 19. People’s perception toward vaccine acceptance have fluctuated with the information flow in various social medias and the severity of COVID 19 cases. This study aimed to assess the level of knowledge and attitude about Covid 19 vaccine among the community people. Methods Quantitative approach with descriptive research design was adopted for the present study. Two hundred 200 adults aged 20 60 years from Angarpada and Mahul residence in Khordha District, Odisha were selected purposively. Adults who gave their consent and were present during the data collection period were included in the study. Pregnant woman and the people have systemic diseases were excluded from the study. The tools used to collect the data were 1. Socio demographic questionnaire, 2. Knowledge questionnaire to assess the Covid 19 vaccination and 3. Attitude scale to assess the attitude on Covid 19 vaccine. The data was analysed by using descriptive and inferential statistics. Results Vaccination status of the adults living in the Khordha district shows that 83 of people vaccinated for COVID 19. Level of knowledge on covid19 vaccine shows that more than half of the people 52.5 had poor knowledge. Highest percentage of adults 47.5 had neutral attitude. The mean knowledge score is 10±3.59 and mean attitude score is 92.38±6.54. There was a very weak positive correlation r = 0.176, p = 0.096 found between the knowledge and attitude. Conclusion The study results indicates that most of the community people are having adequate knowledge and having neutral attitude towards the Covid 19 vaccination. It shows that awareness is needed on the importance of vaccination. Dr. B. Gomathi | Sreya De | Sutapa Roy | Sandip Pradhan | Ankit Barla | Sayantani Das "Knowledge, Attitude and Vaccination Status on Covid-19 among Adults Living in Selected Rural Areas of Khurdha District, Odisha" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-7 | Issue-5 , October 2023, URL: https://www.ijtsrd.com/papers/ijtsrd59985.pdf Paper Url: https://www.ijtsrd.com/medicine/nursing/59985/knowledge-attitude-and-vaccination-status-on-covid19-among-adults-living-in-selected-rural-areas-of-khurdha-district-odisha/dr-b-gomathi
A paper cover the devised policy for patrons in libraries during covid-19. The author has formulated few policy that are helpful for the entire community based on libraries and educational institute
1. The document discusses strategies for libraries and librarians during the COVID-19 pandemic. It outlines three main strategies: providing public health awareness through research on COVID-19, supporting researchers through access to relevant studies and literature, and fulfilling the research needs of library users remotely.
2. Many libraries closed completely during lockdowns, while others provided only minimal services like curbside pickup. Remote services became important, including providing digital content, online reference services, and education on using e-resources.
3. Librarians helped raise awareness of preventive measures and advise on avoiding misinformation. They supported medical researchers through literature and kept users engaged through online activities, fulfilling research needs remotely through tools like Zoom.
CEO of Infinitum Humanitarian Systems Eric Rasmussen, MD, MDM, FACP helped the Medical Devices Group understand the depth of the challenges to global health.
You really have to watch his talk (some of the images will take your breath away) for the full impact of the presentation and please share it on social media and with your colleagues.
Visit http://medgroup.biz/future-global-health for the video recap and transcript and consider the 10x Medical Device Conference to meet speakers like Eric.
For 10x information, see http://medgroup.biz/About-10x
Emerging Propositions for Science Actions for the UN Food System SummitFrancois Stepman
Presentation by: Joachim von Braun, Chair of the Scientific Group of the UNFSS Expectations of the Scientific Group for the Summit
25 June 2021. The Joint Programming Initiative for Agriculture, Food Security and Climate Change (FACCE-JPI) organised a dedicated workshop for invited participants to contribute to the vision and objectives of the upcoming UN Food Systems Summit (UNFSS).
The document discusses the need for a great transition to achieve planetary health. It states that we must learn to produce, consume, construct our cities, manage our landscapes and resources, and view our relationship with nature very differently. It also notes that 6 out of 9 planetary boundaries have already been breached and that all nations must transform their economic systems to prioritize both human well-being and environmental sustainability. The document advocates for adopting a framework of planetary boundaries and social foundations to guide this necessary global transition to a more sustainable future.
International Conference of Multidisciplinary & Interdisciplinary Bioscience (MIBIO 2022) will provide Biological Sciences Research remains the ubiquitous realm in better human health and well being. Multidisciplinary and interdisciplinary Bioscience Research has been stressed for explicit scientific advancements. Impact publications for a wider outreach are ascertained. MIBIO 2022 represents the launch-pad forum for researchers, biologists, students, Scientists and Physicians in peer-reviewed podium encompassing Biological Sciences. The conference takes pleasure in inviting your peer Research for a fantabulous realm of rapport in the arena of multidisciplinary and interdisciplinary Life sciences. The area offers discussions with biomedical and environment impact assessors. This allows you to enlighten, enrich and rejuvenate the multitude of oneness in biological sciences
International Conference of Multidisciplinary & Interdisciplinary Bioscience ...ijbesjournal
International Conference of Multidisciplinary & Interdisciplinary Bioscience (MIBIO 2022) will provide Biological Sciences Research remains the ubiquitous realm in better human health and well being. Multidisciplinary and interdisciplinary Bioscience Research has been stressed for explicit scientific advancements. Impact publications for a wider outreach are ascertained. MIBIO 2022 represents the launch-pad forum for researchers, biologists, students, Scientists and Physicians in peer-reviewed podium encompassing Biological Sciences
Lecture 12 - Mutualisms and Microbiomes - BIS2C Jonathan Eisen
This document contains slides from a lecture on mutualisms and microbiomes. The lecture discusses different types of mutualistic relationships between organisms, including examples like tubeworms that rely on symbiotic bacteria for nutrients. It also examines the human microbiome and how microbes in our bodies contribute to health. The lecture explores how the microbiome can be disturbed by factors like antibiotics and how restoring balance, such as through fecal transplants, can address issues like C. difficile infections.
Similar to Science Day 2021 by Govinda Bhisetti (20)
Anti-Universe And Emergent Gravity and the Dark UniverseSérgio Sacani
Recent theoretical progress indicates that spacetime and gravity emerge together from the entanglement structure of an underlying microscopic theory. These ideas are best understood in Anti-de Sitter space, where they rely on the area law for entanglement entropy. The extension to de Sitter space requires taking into account the entropy and temperature associated with the cosmological horizon. Using insights from string theory, black hole physics and quantum information theory we argue that the positive dark energy leads to a thermal volume law contribution to the entropy that overtakes the area law precisely at the cosmological horizon. Due to the competition between area and volume law entanglement the microscopic de Sitter states do not thermalise at sub-Hubble scales: they exhibit memory effects in the form of an entropy displacement caused by matter. The emergent laws of gravity contain an additional ‘dark’ gravitational force describing the ‘elastic’ response due to the entropy displacement. We derive an estimate of the strength of this extra force in terms of the baryonic mass, Newton’s constant and the Hubble acceleration scale a0 = cH0, and provide evidence for the fact that this additional ‘dark gravity force’ explains the observed phenomena in galaxies and clusters currently attributed to dark matter.
Order : Trombidiformes (Acarina) Class : Arachnida
Mites normally feed on the undersurface of the leaves but the symptoms are more easily seen on the uppersurface.
Tetranychids produce blotching (Spots) on the leaf-surface.
Tarsonemids and Eriophyids produce distortion (twist), puckering (Folds) or stunting (Short) of leaves.
Eriophyids produce distinct galls or blisters (fluid-filled sac in the outer layer)
SDSS1335+0728: The awakening of a ∼ 106M⊙ black hole⋆Sérgio Sacani
Context. The early-type galaxy SDSS J133519.91+072807.4 (hereafter SDSS1335+0728), which had exhibited no prior optical variations during the preceding two decades, began showing significant nuclear variability in the Zwicky Transient Facility (ZTF) alert stream from December 2019 (as ZTF19acnskyy). This variability behaviour, coupled with the host-galaxy properties, suggests that SDSS1335+0728 hosts a ∼ 106M⊙ black hole (BH) that is currently in the process of ‘turning on’. Aims. We present a multi-wavelength photometric analysis and spectroscopic follow-up performed with the aim of better understanding the origin of the nuclear variations detected in SDSS1335+0728. Methods. We used archival photometry (from WISE, 2MASS, SDSS, GALEX, eROSITA) and spectroscopic data (from SDSS and LAMOST) to study the state of SDSS1335+0728 prior to December 2019, and new observations from Swift, SOAR/Goodman, VLT/X-shooter, and Keck/LRIS taken after its turn-on to characterise its current state. We analysed the variability of SDSS1335+0728 in the X-ray/UV/optical/mid-infrared range, modelled its spectral energy distribution prior to and after December 2019, and studied the evolution of its UV/optical spectra. Results. From our multi-wavelength photometric analysis, we find that: (a) since 2021, the UV flux (from Swift/UVOT observations) is four times brighter than the flux reported by GALEX in 2004; (b) since June 2022, the mid-infrared flux has risen more than two times, and the W1−W2 WISE colour has become redder; and (c) since February 2024, the source has begun showing X-ray emission. From our spectroscopic follow-up, we see that (i) the narrow emission line ratios are now consistent with a more energetic ionising continuum; (ii) broad emission lines are not detected; and (iii) the [OIII] line increased its flux ∼ 3.6 years after the first ZTF alert, which implies a relatively compact narrow-line-emitting region. Conclusions. We conclude that the variations observed in SDSS1335+0728 could be either explained by a ∼ 106M⊙ AGN that is just turning on or by an exotic tidal disruption event (TDE). If the former is true, SDSS1335+0728 is one of the strongest cases of an AGNobserved in the process of activating. If the latter were found to be the case, it would correspond to the longest and faintest TDE ever observed (or another class of still unknown nuclear transient). Future observations of SDSS1335+0728 are crucial to further understand its behaviour. Key words. galaxies: active– accretion, accretion discs– galaxies: individual: SDSS J133519.91+072807.4
Dr. Firoozeh Kashani-Sabet is an innovator in Middle Eastern Studies and approaches her work, particularly focused on Iran, with a depth and commitment that has resulted in multiple book publications. She is notable for her work with the University of Pennsylvania, where she serves as the Walter H. Annenberg Professor of History.
Presentation of our paper, "Towards Quantitative Evaluation of Explainable AI Methods for Deepfake Detection", by K. Tsigos, E. Apostolidis, S. Baxevanakis, S. Papadopoulos, V. Mezaris. Presented at the ACM Int. Workshop on Multimedia AI against Disinformation (MAD’24) of the ACM Int. Conf. on Multimedia Retrieval (ICMR’24), Thailand, June 2024. https://doi.org/10.1145/3643491.3660292 https://arxiv.org/abs/2404.18649
Software available at https://github.com/IDT-ITI/XAI-Deepfakes
Embracing Deep Variability For Reproducibility and Replicability
Abstract: Reproducibility (aka determinism in some cases) constitutes a fundamental aspect in various fields of computer science, such as floating-point computations in numerical analysis and simulation, concurrency models in parallelism, reproducible builds for third parties integration and packaging, and containerization for execution environments. These concepts, while pervasive across diverse concerns, often exhibit intricate inter-dependencies, making it challenging to achieve a comprehensive understanding. In this short and vision paper we delve into the application of software engineering techniques, specifically variability management, to systematically identify and explicit points of variability that may give rise to reproducibility issues (eg language, libraries, compiler, virtual machine, OS, environment variables, etc). The primary objectives are: i) gaining insights into the variability layers and their possible interactions, ii) capturing and documenting configurations for the sake of reproducibility, and iii) exploring diverse configurations to replicate, and hence validate and ensure the robustness of results. By adopting these methodologies, we aim to address the complexities associated with reproducibility and replicability in modern software systems and environments, facilitating a more comprehensive and nuanced perspective on these critical aspects.
https://hal.science/hal-04582287
BIRDS DIVERSITY OF SOOTEA BISWANATH ASSAM.ppt.pptxgoluk9330
Ahota Beel, nestled in Sootea Biswanath Assam , is celebrated for its extraordinary diversity of bird species. This wetland sanctuary supports a myriad of avian residents and migrants alike. Visitors can admire the elegant flights of migratory species such as the Northern Pintail and Eurasian Wigeon, alongside resident birds including the Asian Openbill and Pheasant-tailed Jacana. With its tranquil scenery and varied habitats, Ahota Beel offers a perfect haven for birdwatchers to appreciate and study the vibrant birdlife that thrives in this natural refuge.
Candidate young stellar objects in the S-cluster: Kinematic analysis of a sub...Sérgio Sacani
Context. The observation of several L-band emission sources in the S cluster has led to a rich discussion of their nature. However, a definitive answer to the classification of the dusty objects requires an explanation for the detection of compact Doppler-shifted Brγ emission. The ionized hydrogen in combination with the observation of mid-infrared L-band continuum emission suggests that most of these sources are embedded in a dusty envelope. These embedded sources are part of the S-cluster, and their relationship to the S-stars is still under debate. To date, the question of the origin of these two populations has been vague, although all explanations favor migration processes for the individual cluster members. Aims. This work revisits the S-cluster and its dusty members orbiting the supermassive black hole SgrA* on bound Keplerian orbits from a kinematic perspective. The aim is to explore the Keplerian parameters for patterns that might imply a nonrandom distribution of the sample. Additionally, various analytical aspects are considered to address the nature of the dusty sources. Methods. Based on the photometric analysis, we estimated the individual H−K and K−L colors for the source sample and compared the results to known cluster members. The classification revealed a noticeable contrast between the S-stars and the dusty sources. To fit the flux-density distribution, we utilized the radiative transfer code HYPERION and implemented a young stellar object Class I model. We obtained the position angle from the Keplerian fit results; additionally, we analyzed the distribution of the inclinations and the longitudes of the ascending node. Results. The colors of the dusty sources suggest a stellar nature consistent with the spectral energy distribution in the near and midinfrared domains. Furthermore, the evaporation timescales of dusty and gaseous clumps in the vicinity of SgrA* are much shorter ( 2yr) than the epochs covered by the observations (≈15yr). In addition to the strong evidence for the stellar classification of the D-sources, we also find a clear disk-like pattern following the arrangements of S-stars proposed in the literature. Furthermore, we find a global intrinsic inclination for all dusty sources of 60 ± 20◦, implying a common formation process. Conclusions. The pattern of the dusty sources manifested in the distribution of the position angles, inclinations, and longitudes of the ascending node strongly suggests two different scenarios: the main-sequence stars and the dusty stellar S-cluster sources share a common formation history or migrated with a similar formation channel in the vicinity of SgrA*. Alternatively, the gravitational influence of SgrA* in combination with a massive perturber, such as a putative intermediate mass black hole in the IRS 13 cluster, forces the dusty objects and S-stars to follow a particular orbital arrangement. Key words. stars: black holes– stars: formation– Galaxy: center– galaxies: star formation
1. Science Day 2021
Wednesday, December 29, 2021
9:45 AM Zoom session starts / Nobel Ceremony
10:00 - 10:15 AM Introductions - all students
10:15 - 12:00 PM Nobel Prizes 2021
12:00 - 1:00 PM Lunch & Chitchat on 2021 happenings
1:00 - 2:00 PM SARS CoV2 variants, vaccines, treatmemts
2:00 - 2:30 PM Insulin - 100 years
2:30 - 4:00 PM Breakthroughs in Science 2021
4:00 - 4:30 PM Q&A
Govinda Rao Bhisetti, Ph. D.
Science Day 2021 - Govinda Bhisetti 1
2. Nobel Award Ceremony 2021
Cancelled due to pandemic
10 December 2021
2021 Nobel Prize award ceremony – YouTube
https://youtu.be/ieuZUQRkZBU
Science Day 2021 - Govinda Bhisetti 2
3. 3
This year's monetary award is 10 million Swedish krona (SEK) - US$1.1 million
Nobel Prize
"…The whole of my remaining realizable estate shall be dealt with in the following way: The
capital shall be invested by my executors in safe securities and shall constitute a fund, the
interest on which shall be annually distributed in the form of prizes to those who, during the
preceding year, shall have conferred the greatest benefit on mankind ... ; one part to the person
who shall have made the most important discovery within the domain of physiology or
medicine; ... The prizes for ... shall be awarded by ... that for physiology or medicine by the
Carolinska Institute in Stockholm; ... "
Alfred Nobel’s “will” was signed in Paris on 27 November 1895. The statutes of the Nobel
Foundation, which were officially approved by the Swedish Government on 29 June 1900.
120 years ago, the first Nobel Prizes were awarded, including the first one in Physics for the
discovery of X-rays.
https://youtu.be/ykUXN0gkt7M
https://youtu.be/uZLK_J2NfX0
Science Day 2021 - Govinda Bhisetti
4. 4
Prize Announcement Schedule
• Monday, October 4, 2021 PHYSIOLOGY or MEDICINE
• Tuesday, October 5, 2021 PHYSICS
• Wednesday, October 6, 2021 CHEMISTRY
• Thursday, October 7, 2021 LITERATURE
• Friday, October 8, 2021 PEACE
• Monday, October 11, 2021 ECONOMICS
Nobel Day: December 10, 2021
Science Day 2021 - Govinda Bhisetti
5. 5
2021 LITERATURE PRIZE
Born in 1948, Abdulrazak Gurnah mainly grew up on the island of
Zanzibar in the Indian Ocean before arriving in England as a
refugee at the end of the 1960s. Following the peaceful liberation
from the UK’s colonial rule in December 1963, when Zanzibar went
through a revolution under the regime of President Abeid Karume, it
led to the oppression and persecution of citizens of Arab origin.
However, Gurnah belonged to the victimised ethnic group and was
forced to leave his family and his country, which was called the
Republic of Tanzania. He was unable to return to Zanzibar until
1984.
Bibliography – a selection
Works in English
Memory of Departure. – London : Jonathan Cape, 1987
Pilgrims Way. – London : Jonathan Cape, 1988
Dottie. – London : Jonathan Cape, 1990
Paradise. – London : Hamish Hamilton, 1994
Admiring Silence. – London : Hamish Hamilton, 1996
By the Sea. – London : Bloomsbury, 2001
Desertion. – London : Bloomsbury, 2005
The Last Gift. – London : Bloomsbury, 2011
Gravel Heart. – London : Bloomsbury, 2017
Afterlives. – London : Bloomsbury, 2020
“I just want to write as trustfully as I can, without trying
to say something noble."
"for his uncompromising and compassionate penetration of the effects of colonialism and the fate of the refugee in
the gulf between cultures and continents."…"
Science Day 2021 - Govinda Bhisetti
6. 6
2021 PEACE PRIZE
"for their efforts to safeguard freedom of expression, which is a precondition for
democracy and lasting peace”
Maria Ressa, 58, the chief executive and co-
founder of the online news platform Rappler,
praised for exposing abuses of power and growing
authoritarianism under the Philippine president,
Rodrigo Duterte, is facing charges that could lead
to about 100 years in jail.
Dimitry Muratov, 59, the editor-in-chief of
Novaya Gazeta is as one of the most prominent
defenders of freedom of speech in Russia today.
“Novaya Gazeta is the most independent
newspaper in Russia today, with a fundamentally
critical attitude towards power,”
Science Day 2021 - Govinda Bhisetti
8. 8
How much more you would earn
if you chose to study longer?
For men born in the US during the
1930s, earnings were, on average, 7%
higher for those with one additional
year of education.
How do we know that the extra year of
education is the cause of higher
income?
Angrist and Krueger were able to use
the natural experiment to establish a
causal relationship showing that more
education leads to higher earnings: the
effect of an additional year of education
on income was 9%.
Science Day 2021 - Govinda Bhisetti
9. 9
Discovery of Receptors that
sense temperature and touch
https://youtu.be/PPO8N2ZnslI
Science Day 2021 - Govinda Bhisetti
10. 10
How do we sense our environment?
David Julius’ presentatopn:
https://youtu.be/bOLHKX0Li3M Science Day 2021 - Govinda Bhisetti
11. 11
Receptors of temperature perception
Transient receptor potential vanilloid 1
Transient receptor potential melastatin 8
Science Day 2021 - Govinda Bhisetti
16. 16
Carbon Dioxide and Global Temperature
Explained
https://youtu.be/6WSPf2zTdMg
Announcement
https://youtu.be/M6-HH4uLwys
Manabe demonstrated how increases in the amount of
carbon dioxide in the atmosphere would increase global
temperature, laying foundations for current models.
Science Day 2021 - Govinda Bhisetti
17. 17
Climate fingerprints
Hasselmann created a model that linked
weather and climate, helping explain why
climate models can be reliable despite the
seemingly chaotic nature of the weather.
Science Day 2021 - Govinda Bhisetti
18. 18
Interplay of disorder and fluctuations
Parisi “built a deep physical and
mathematical model” that made it possible to
understand complex systems in fields as
different as mathematics, biology,
neuroscience and machine learning.
More videos
https://www.youtube.com/watch?v=5DCZyAuY1oY
Science Day 2021 - Govinda Bhisetti
20. 20
Asymmetry in Chemistry
A carbon atom bonded to four different atoms/groups loses all symmetry
The 2021 Nobel Prize in Chemistry
https://youtu.be/MYOsCjbNOkI
Myth of orange vs. lemon
https://youtu.be/W9JpRg8M1qk
Science Day 2021 - Govinda Bhisetti
21. 21
Catalysis
Enzymes are highly efficient catalysts. They speed up reactions up to 10 million times as
compared to the uncatalyzed reactions.
Prior to 2000, metals were used to catalyze organic reactions in the lab.
Catalysis is the process of increasing the rate of a chemical reaction by
adding a substance known as a catalyst
Science Day 2021 - Govinda Bhisetti
22. 22
Advent of Modern Oragnocatalysis:
Asymmetric Aminocatalysis
Science Day 2021 - Govinda Bhisetti
26. 26
2021: Second Year of COVID19
Coronavirus Cases Worldwide:
282,684,232
Deaths:
5,428,123
Recovered:
251,623,469
Updated: December 28, 2021, 20:23 GMT
Science Day 2021 - Govinda Bhisetti
27. 27
Outbreaks in 2009 …
Is Omicron less
fatal as it is
spreading faster?
Science Day 2021 - Govinda Bhisetti
28. 28
Virus?
• A microscopic (< 0.2 uM) infectious agent
• “Non-living” entity – “metabolically inert”
• Typically contain DNA or RNA
• Can only replicate (propagate) inside the
living cells of organisms
• Can adapt to immune response as it
mutates rapidly
• Highly diverse, limited host range
• Survival dilemma?
• Difficult to treat viral infections
• Viruses are responsible for about 60% of
all infectious diseases
• Viral infections cause or contribute to 20%
of all human cancers
Virus has smallest genome
Science Day 2021 - Govinda Bhisetti
33. 33
US Approved Treatments for COVID19
COVID-19 Vaccines Authorized for Emergency Use or FDA-Approved
Comirnaty and Pfizer-BioNTech COVID-19 Vaccine
Moderna COVID-19 Vaccine
Janssen COVID-19 Vaccine
SARS-COV-2-targeting Monoclonal Antibodies
REGEN-COV (Casirivimab and Imdevimab)
Sotrovimab
Bamlanivimab and Etesevimab
SARS-COV-2-targeting Monoclonal Antibodies
remdesvir (Gilead)
paxlovid (Pfizer)
Molnupairavir (Merck)
Widespread vaccination is the best option to protect everyone
from COVID-19 and related complications.
Science Day 2021 - Govinda Bhisetti
34. 34
Children and teens who are fully vaccinated can safely resume many activities that they did prior to the pandemic.
Everyone ages 16 years and older can get a COVID-19 booster shot.
The federal government is providing the COVID-19 vaccine free of charge
https://www.cdc.gov/coronavirus/2019-ncov/vaccines/recommendations/children-teens.html
Science Day 2021 - Govinda Bhisetti
40. 40
1. Protein structures for all
2. Ancient soil DNA comes of age
3. Fusion’s day in the Sun?
4. Potent pills boost COVID-19 arsenal
5. A psychedelic PTSD remedy
6. Artificial antibodies tame infectious
diseases
7. NASA lander uncovers the Red Planet’s
core
8. At last, a crack in particle physics’
standard model?
9. CRISPR fixes genes inside the body
10. Embryo ‘husbandry’ opens windows into
early development
Breakthrough of the Year 2021
23 December 2011
https://www.science.org/content/article/breakthrough-2021
Science Day 2021 - Govinda Bhisetti
41. 10. Embryo ‘husbandry’
opens windows into early
development
helps in understaning
miscarriages and birth defects
• Studies on human embryos are constrained by legal, practical, and ethical limitations.
• Mouse embryos reared far longer than before, and embryo replicas made from human
stem cells or reprogrammed adult cells are unveiled this year for these studies.
• Scientists have struggled to grow mouse embryos outside a mother mouse’s body for
much longer than 3 or 4 days. But in March, one team reported a recipe for stretching
that to 11 days. A key step, they found, was rotating the jars containing the embryos on
a device that resembles a miniature Ferris wheel.
• One team made blastocyst replicas from human embryonic stem cells and induced
pluripotent stem (iPS) cells, stem cells repro- grammed from specialized adult cells.
41
Science Day 2021 - Govinda Bhisetti
A mouse embryo grows in a rotating jar. Such embryos can help
researchers better understand the early stages of human development.
42. 9. CRISPR fixes
genes inside the body
Scientists deployed
CRISPR directly in the
body. In small studies, the
strategy reduced a toxic
liver protein and modestly
improved vision in people
with inherited blindness.
• The gene-editing tool CRISPR had its first clinical victory in 2020, when it appeared to
cure people with two inherited blood disorders, sickle cell disease and beta-
thalassemia.
• Those treatments took place in a lab dish: Scientists removed defective blood stem
cells from patients, edited them, and reinfused the cells into patients.
• But getting CRISPR to work inside a person, or in vivo, poses significant challenges.
Before CRISPR’s molecular components can correctly modify a specific gene, they
must be ferried safely to the right cells in the right quantities.
• Researchers at Intellia Therapeutics and Regeneron Pharmaceuticals gave six
patients an infusion of tiny fat balls encasing a guide RNA and the RNA instructions
for CRISPR’s genome-snipping enzyme. The team hoped the patients’ own liver cells
would take up the particles and make the CRISPR components, which would snip both
strands of DNA at the TTR gene. The cell’s repair system would mend the cuts
imperfectly, leaving the gene disabled. It worked: After 4 weeks, average blood levels
of TTR dropped 52% or 87%.
• In another study, researchers at Editas Medicine injected a harmless virus carrying
CRISPR DNA into the eyes of six adults with an inherited vision disorder. After 3 to 6
months, two patients—who had been almost completely blind—could sense more light,
and one could navigate an obstacle course in dim light.
42
Guide RNA (blue) from a CRISPR injection
leads a DNA-cutting enzyme (white) to its
target (orange).
Science Day 2021 - Govinda Bhisetti
43. 8. At last, a crack in
particle physics’
standard model?
The muon’s magnetism
gives scientists an
indirect way to search
for additional,
undiscovered particles.
• Standard model, accounts for three forces—electromagnetism,
the strong nuclear force, and the weak nuclear force—and two
dozen fundamental particles (including muon).
• In an earlier (1997-2001), they found an anomaly in muon’s
magnetism and is confirmed this year by a purer muon beam.
• Tiny discrepancies from the standard model’s predictions
could yield more clues to the hoped-for new physics.
• Scientists hope to repeat these experiments next year at
Europe’s Large Hadron Collider, the world’s biggest atom
smasher.
43
muons twirl like compass needles in a magnetic field mapped with an accuracy of 30 parts per billion (Fermi Accelerator Laboratory,)
Science Day 2021 - Govinda Bhisetti
44. 7. NASA lander uncovers
the Red Planet’s core
bringing Mars’s planetary core
into focus.
• The interior of a rocky planet is a kind of time machine: Its dense core, viscous mantle, and hardened
crust can reveal how it coalesced, churned, and settled into what it is today.
• NASA’s InSight lander are bringing Mars’s planetary core into focus. InSight picked up a handful of
moderate quakes this year and helped chart the planet’s depths.
• Offsets in the quakes’ seismic waves revealed that the martian crust is layered and less than 40
kilometers thick—thinner than Earth’s continental crust. That thin shell would have let Mars quickly
shed its early internal heat.
• InSight found the martian mantle lacked the insulating lower layer seen in Earth’s. The mantle was
also shallow, squeezed between the crust and an unusually large, liquid core that occupies more than
half of Mars’s width.
• Scientists concluded that the core’s density is low, and that a mixture of light elements such as sulfur
likely keep its iron and nickel liquid, despite the planet’s rapid heat loss.
44
Science Day 2021 - Govinda Bhisetti
Waves from mars-quakes showed the planet has a thin crust, a shallow mantle, and an unusually large liquid core
45. 6. Artificial antibodies tame
infectious diseases
made inroads against SARS-CoV-
2 and other life-threatening
pathogens, including respiratory
syncytial virus (RSV), HIV, and
malaria parasites.
• Labmade antibodies called monoclonals have revolutionized the treatment of some cancers
and autoimmune diseases.
• SARS-CoV-2 mAbs showed promising results in clinical trials in 2020, and by late this year,
the U.S. Food and Drug Administration had granted emergency use authorization to three to
treat COVID-19 and, in some cases, prevent infection.
• To make monoclonal antibodies (mAbs), scientists isolate the most powerful antibodies from
lab animals and humans and reproduce them in massive quantities.
• With advances in cloning, animal models, and x-ray crystallo- graphy, researchers can now
make and screen more mAbs than ever before, simplifying their search.
• High costs and the need to infuse mAbs in a clinic have put them out of reach for many. But
as prices plummet, injections replace infusions, and more potent mAbs come to market, they
may become standard weapons in the infectious disease arsenal.
45
Science Day 2021 - Govinda Bhisetti
Antibodies (red and blue) attack SARS-CoV-2 (purple) in
an artist’s concept.
46. 5. A psychedelic PTSD
remedy
MDMA (3,4-methylenedioxy-
methamphetamine),
popularly called ecstasy,
significantly reduced
symptoms in patients with
post-traumatic stress
disorder (PTSD).
• 8 million adults in the US suffer from PTSD each year.
• Post-traumatic stress disorder is a “psychiatric disorder that can occur in people
who have experienced or witnessed a traumatic event such as a natural disaster,
a serious accident, war/combat, or other violent personal assault.”
• The mind-altering power of psychedelic drugs has raised hopes that they can
ease psychiatric disease, but few large, rigorous trials have shown they’re
effective.
• Academic labs and companies explore the potential of MDMA and other
psychedelics to treat conditions like depression, anxiety, and addiction.
• COMPASS Pathways announced positive results from a 233-participant
randomized trial of psilocybin, the substance in so-called magic mushrooms, in
people with treatment-resistant depression.
46
Science Day 2021 - Govinda Bhisetti
47. 4. Potent pills boost
COVID-19 arsenal
Antiviral pills that prevent
symptoms and death
• Antiviral pills from drugmakers Pfizer and Merck & Co. prevent
symptoms and death if taken early in infection.
• They are approved by FDA in December 23 and 24 by FDA.
• More antivirals are in clinical trials.
• Scientists are quick to stress that antivirals can’t replace
vaccination.
47
Science Day 2021 - Govinda Bhisetti
48. 3. Fusion’s day
in the Sun?
Fusion reaction that
came tantalizingly
close to reaching
official “breakeven,”
the point
• Fusion, which powers the Sun and other stars, has long been seen as a solution
to Earth’s energy problems. But it is notoriously difficult.
• In an August, the U.S. National Ignition Facility (NIF) produced a fusion reaction
that came tantalizingly close to reaching official “breakeven,” the point at which a
reaction produces more energy than the laser energy needed to kindle it.
• Researchers think burning plasma (fusion reaction) generated enough heat to
spread through the compressed fuel like a flame.
• The team is trying to understand the shot’s high yield and figure out how to tweak
starting conditions to do even better, by using larger or smoother fuel capsules,
more even layers of frozen fuel, or higher quality laser pulses. They’re also making
efforts to replicate the shot and private fusion projects are making progress.
• Many formidable challenges in materials science and engineering remain to be
tackled before fusion can become a practical power source.
48
To produce NIF’s fusion shot, 192 laser beams converged around a tiny fuel pellet.
Science Day 2021 - Govinda Bhisetti
49. 2. Ancient soil DNA
comes of age
“dirt DNA” to
reconstruct the identity
of cave dwellers around
the world
Antiviral pills that
prevent symptoms and
death
• DNA from fossils has transformed the study of human and animal evolution,
revealing unknown relationships, tracing early migrations. The entire field
depends on just 23 archaic genomes, 18 of them from Neanderthals.
• By 2003, evolutionary geneticists showed discarded DNA (the free-floating DNA
they shed into air, water, and soil) could persist for thousands of years. This year,
scientists used nuclear DNA to chart the human and animal occupation of three
caves.
• In Spain’s Estatuas Cave, nuclear DNA revealed the genetic identity and sex of
humans who lived there 80,000 to 113,000 years ago and suggested one lineage
of Neanderthals replaced several others after a glacial period that ended
100,000 years ago.
• In 25,000-year-old soil from Georgia’s Satsurblia Cave, scientists found a female
human genome from a previously unknown line of Neanderthals, along with the
genetic traces of a bison and a now-extinct wolf.
• By comparing 12,000-year-old black bear DNA from Mexico’s Chiquihuite Cave
with that of modern bears, scientists discovered that after the last ice age, the
cave bears’ descendants migrated as far north as Alaska.
Science Day 2021 - Govinda Bhisetti 49
50. 50
1. Artificial intelligence predicts how proteins fold
• Univ. of Washington AI protein folding discovery wins
‘Breakthrough of the Year’ award from Science
• With 20 amino acid building blocks that fit together like
beads on a string, the options for how an individual protein
might fold are numerous. Folding depends on multiple
molecular interactions within the protein and its
environment, which are constantly shifting during the
folding process.
• With 20 amino acid building blocks that fit together like
beads on a string, the options for how an individual protein
might fold are numerous. Folding depends on multiple
molecular interactions within the protein and its
environment, which are constantly shifting during the
folding process.
• Researchers traditionally decipher structures using
laborious techniques such as x-ray crystallography and
cryo–electron microscopy. But detailed molecular maps
only exist for about 170,000 of the 200 million known
proteins.
• “The breakthrough in protein folding is one of the greatest
ever in terms of both the scientific achievement and the
enabling of future research,” wrote H. Holden Thorp, a
biochemist and the Editor-in-Chief of Science in an
editorial.
Predicted structure (blue) and experimentally determined (green)
match almost perfectly.
AlphaFold2: a solution to a 50-year-old grand challenge in biology
November 2020
Science Day 2021 - Govinda Bhisetti
51. 51
Science Breakthrough of the Year 2020:
Protein structures for all
AI-powered predictions show proteins finding their shapes
https://www.science.org/content/article/breakthrough-2021#section_video
https://youtu.be/iUMpm3tYsVE
Science Day 2021 - Govinda Bhisetti