SAR (Structure Activity Relationship) of Morphine
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This document discusses the role of pharmacognosy in various traditional medicine systems including Ayurveda, Siddha, Unani, and allopathy. It provides an overview of each system and explains how pharmacognosy plays an important role in the development and standardization of herbal medicines used in the formulations of each traditional system. Pharmacognosy is involved in the identification, authentication, and quality control of medicinal plants used as the basis for many medicines within these traditional systems.
General anesthetic and pre anesthetics
The document discusses different aspects of anesthesia including:
1. Anesthesia refers to reversible loss of sensation and consciousness and is achieved through anesthetic agents that induce loss of pain and sensation along with loss of reflexes.
2. There are two main types of anesthesia - local anesthesia and general anesthesia. General anesthesia involves drug-induced absence of all sensation allowing surgery.
3. Anesthesia works through several stages from initial analgesia to eventual respiratory paralysis if overdosed. Proper pre-anesthesia medications are used to make the anesthesia safer and more comfortable for the patient.
To study effect of drug on ciliary motility of frog oesophagus
1. The document describes an experiment to study the effects of drugs on ciliary motility in a frog esophagus. Physostigmine and atropine were tested.
2. Physostigmine is a cholinesterase inhibitor that prolongs the action of acetylcholine, increasing ciliary movements. Atropine is an anticholinergic that blocks acetylcholine receptors, decreasing ciliary movements.
3. The procedure involved measuring the time taken for poppy seeds to move along the esophagus under the influence of different drugs. Physostigmine decreased transit time, while atropine increased it, demonstrating their effects on ciliary motility.
Suspensions
This document discusses pharmaceutical suspensions. It defines suspensions as dispersions of solid drug particles in a liquid vehicle. Suspensions are classified based on particle size as molecular dispersions (<1nm), colloidal dispersions (1nm-0.5um) or coarse dispersions (>0.5um). Most pharmaceutical suspensions are coarse dispersions. The document outlines factors to consider in suspension formulation including particle wetting and size, sedimentation rate, electrokinetic properties, and methods of controlling flocculation. Structured vehicles and controlled flocculation are described as methods for producing stable suspensions. Key qualities of ideal suspensions are also provided such as resistance to settling and caking.
ANTI ALZHEIMER'S AGENTS / DRUGS USED IN THE TREATMENT OF ALZHEIMER'S DISEASE
This document discusses drugs used to treat Alzheimer's disease. It focuses on cholinergic activators like rivastigmine and donepezil, which work by inhibiting the breakdown of acetylcholine in the brain to increase levels of this neurotransmitter that is deficient in Alzheimer's patients. It also discusses memantine, an NMDA receptor antagonist that blocks glutamate receptors and protects nerve cells from damage. Common side effects of these drugs include nausea, diarrhea, vomiting and headaches. The document provides details on the mechanisms and effects of rivastigmine and memantine as two major drug classes used to treat symptoms of Alzheimer's disease.
Alcohol & Disulfiram
1. Alcohol is produced by fermentation of sugars and its pharmacological actions include local irritation, effects on cardiovascular and respiratory systems, hypoglycemia, impacts on temperature regulation and more.
2. Chronic alcoholism can lead to complications like cirrhosis of the liver, hypertension, cardiomyopathy and more. Treatments include naltrexone, acamprosate, topiramate and disulfiram.
3. Methanol poisoning results in symptoms like vomiting, headache and can cause blindness or death if not treated. Treatments include gastric lavage, ethanol administration, fomepizole, hemodialysis and folate therapy.
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department of Pharmaceutical Technology.
Anna university- BIT
Tiruchirappalli.
As per PCI syllabus for B Pharm / 2nd Year ,III Semester.
UNIT-III / Coarse dispersion
Med chem hypnotics and sedatives
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ISO/IEC 27001, ISO/IEC 42001, and GDPR: Best Practices for Implementation and...
Denis is a dynamic and results-driven Chief Information Officer (CIO) with a distinguished career spanning information systems analysis and technical project management. With a proven track record of spearheading the design and delivery of cutting-edge Information Management solutions, he has consistently elevated business operations, streamlined reporting functions, and maximized process efficiency.
Certified as an ISO/IEC 27001: Information Security Management Systems (ISMS) Lead Implementer, Data Protection Officer, and Cyber Risks Analyst, Denis brings a heightened focus on data security, privacy, and cyber resilience to every endeavor.
His expertise extends across a diverse spectrum of reporting, database, and web development applications, underpinned by an exceptional grasp of data storage and virtualization technologies. His proficiency in application testing, database administration, and data cleansing ensures seamless execution of complex projects.
What sets Denis apart is his comprehensive understanding of Business and Systems Analysis technologies, honed through involvement in all phases of the Software Development Lifecycle (SDLC). From meticulous requirements gathering to precise analysis, innovative design, rigorous development, thorough testing, and successful implementation, he has consistently delivered exceptional results.
Throughout his career, he has taken on multifaceted roles, from leading technical project management teams to owning solutions that drive operational excellence. His conscientious and proactive approach is unwavering, whether he is working independently or collaboratively within a team. His ability to connect with colleagues on a personal level underscores his commitment to fostering a harmonious and productive workplace environment.
Date: May 29, 2024
Tags: Information Security, ISO/IEC 27001, ISO/IEC 42001, Artificial Intelligence, GDPR
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What is Digital Literacy? A guest blog from Andy McLaughlin, University of Aberdeen
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