Linguify.S software allows SAP to be displayed, printed, and translated into various regional languages like Tamil. The software works by replacing original strings with substitution strings in other languages. It supports SAP GUI, SAP WebUI, Crystal Reports, and SAP CRM. To set it up, the Linguify.S software must be downloaded, installed, and configured to select the desired regional language. Once configured, SAP can be launched and will display in the selected regional language.