rh incompatibility

1. PREGNANCY IN A RH-NEGATIVE
WOMAN

2. • Landsteiner and Weiner in the year
1940, discovered specific
unknown antigen in the human red
cells.
• As it was also present in the
Rhesus monkeys, the antigen was
named Rh.
• The individual having the antigen
is called Rh-positive and in whom
it is not present, is called Rh-
negative.

4. INCIDENCE
• In India, the incidence is about 5–10%
(South India – 5%, North India – 10%)
in hospital statistics.
• Overall a Rh-negative woman having
the chance of Rh-positive fetus is
60%, irrespective of the father’s
genotype.