John Wallis, an English mathematician in the 1600s, was the first to develop concepts of zero, negative, and fractional exponents. The term polynomial refers to expressions with one variable. Robert Recorde introduced the modern symbol for equality in 1557. Polynomial expressions and cancelling common factors are used in genetics to model gene combinations during fertilization. Key algebraic concepts like subtraction and division were developed through additive inverses and multiplication by reciprocals. The word "algebra" originates from a book by the Arabic mathematician Al-Khowarizmi that focused on solving linear equations.