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Art of Imaging:
Diagnostic Ultrasound Image Artifacts
James A. Zagzebski, Ph.D.,
Department of Medical Physics, University of Wisconsin – Madison
Zheng Feng Lu, Ph.D.,
Department of Radiology, University of Chicago
AAPM Meeting
July 20-24, 2014, Austin Texas
Introduction
• Underlying assumptions when forming
B-mode images
• Artifacts for specular reflectors
• Reverberations
• Scatter effects, speckle, speckle
reduction
• Mirror image artifacts
• Common artifacts in Doppler
• Refraction
• Attenuation, shadowing, enhancement
For those with “SAMs” audience response clickers,
Trial question:
Illinois is known as the “Land of Lincoln;” Wisconsin is called
“________.”
20%
20%
20%
20%
20% 1. The Beehive State
2. America’s Dairyland
3. The Coyote state
4. The Beaver State
5. The Lone Star State
10
1. The Beehive State (Utah)
2. America’s Dairyland (Wisconsin)
3. The Coyote state (S. Dakota; officially, Mt Rushmore state)
4. The Beaver State (Oregon)
5. The Lone Star State (Texas)
Answer 2 America’s Dairyland
( http://en.wikipedia.org/wiki/List_of_U.S._state_nicknames )
Echo Arrival Time
Underlying Assumptions when forming images:
(Assumes a Sound Speed, usually 1,540 m/s)
Direct “beams” over scanned
region
150-200 “acoustic scan lines”
(beam lines)
25-50 sweeps/s
Pulse repetition frequency of
about 25 x 200 = 4,000 /s
Dots representing echo signals are displayed along a line that represents the
ultrasound beam axis. Location along the line depends on echo arrival times.
Underlying Assumptions when forming images:
Dot brightness represents the echo signal amplitude. Try to
optimize TGC, etc., so this indicates relative reflectivity.
Underlying Assumptions when forming images:
Which of the following is NOT assumed implicitly
during the formation of a conventional ultrasound B-
mode image?
20%
20%
20%
20%
20% 1. echoes originate from along “beam” axes
2. wave speed is 1540 m/s
3. brightness indicates reflectivity level
4. speckle reveals microscopic details of scatterers
5. TGC corrects for attenuation throughout
10
B-mode Imaging Assumptions
• Pulse-echo transit times can be converted to
reflector depth through uniform tissue models.
• Echoes originate (only) from locations along the
transmit-receive axes of pulse propagation path.
• First order correction schemes (such as TGC)
adequately account for acoustic wave attenuation
and absorption.
• Display brightness encodes tissue echogenicity.
Answer 4: “speckle reveals microscopic details of
scatterers” is not an assumption.
JA Zagzebski, Essentials of Ultrasound Physics, Mosby, St Louis, 1996. Chapter 7.
F Kremkau, Chapter 6 in Textbook of Diagnostic Sonography, SL Hagen Ansert, Elsevier,
2012, Chapter 6.
Echoes from the superior pole of the
kidney are weaker (do not appear as
bright) than those from the proximal
surface because of changes in ____
over the liver-kidney interface.
20%
20%
20%
20%
20% 1. Beam focusing
2. frequency
3. acoustic impedance
4. depth
5. incident beam angle
10
Answer 5: changes in incident beam angle
Specular Reflector: effects on ability to
outline an object
11
Impedance change at
liver-to-kidney interface
likely is uniform
Beams from a
curvilinear array
emerge perpendicular
to surface of aperture
Strong effects of beam
angle on detected
amplitude, display
brightness
JA Zagzebski, Essentials of
Ultrasound Physics, Mosby, St
Louis, 1996. Chapter 7.
Spatial Compounding
 Uses “beam steering”
technology
 Combines scans from different
angles
 More completely outlines
interfaces that are not
perpendicular to primary
beam direction
 Smoothes random dots called
speckle
Š 2000 ATL Ultrasound
.
Entrekin RR1, Porter BA, Sillesen HH, Wong AD, Cooperberg PL. “ Real-time spatial compound imaging:
application to breast, vascular, and musculoskeletal ultrasound.” Semin Ultrasound CT MR. 2001 Feb;22(1):50-64
20%
20%
20%
20%
20% 1. A focal mass
2. Higher speed of sound in this region
3. Side lobe artifacts
4. Reverberations
5. Stress from a swollen kidney
10
The region of brighter echoes
in this longitudunal view of
the liver and kidney are most
likely due to which of the
following?
Focal
brightness
Images of a Gammex 403 Phantom
Transducer in direct contact
12 mm tissue-like layer between the
transducer and the phantom
Answer 4: Reverberations (likely, the most ubiquitous ultrasound artifact)
JA Zagzebski, Essentials of Ultrasound Physics, Elsevier, 1996.
FW Kremkau, Sonography Principles and Instruments,, Elsevier, 2011.
Reverberation Artifacts
16
Reverberation Artifacts
Air bubble in
a water-filled
condom.
17
Reverberations
Reverberations here
Produce “noise” here
18
.
Entrekin RR1, Porter BA, Sillesen HH, Wong AD, Cooperberg PL. “ Real-time spatial compound
imaging: application to breast, vascular, and musculoskeletal ultrasound.” Semin Ultrasound CT
MR. 2001 Feb;22(1):50-64
Reverberations
Reverberations here
Produce “noise” here
19
.
Entrekin et al, Semin Ultrasound CT MR.
2001 Feb;22(1):50-64
Reverberations
Park et al, “Introperative Contrast –enhanced
sonographic …,” J Ultrasound Med 35(7): 1287-91,
2014.
Donadon & Torzilli, Am J
Roent,198(4): April, 2012.
MedlinePlus, 2012
Reverbs
Body wall
No Reverbs
Fundamental problem: must
transmit through tissue layers
Ideal(??)
Harmonic Imaging
Transmit a low-frequency pulse (2-5 MHz)
The pulse gradually distorts due to nonlinear propagation
 second harmonic generation
Harmonic field is weaker than fundamental as incident beam
propagates through superficial layers 21
.
Entrekin et al, Semin Ultrasound
CT MR. 2001 Feb;22(1):50-64
Reverberations
22
Reverbs weak
Harmonic Beam
HarmonicBeam (increases
as depth increases)
23
“Clarify” (Siemens Medical Solutions)
Uses power Doppler signals to remove unwanted gray scale echo signals from vessels.
Doppler flow phantom After applying Clarify
Reverberation Artifacts
Examples of reverberations occurring within distal objects,
not back and forth between transducer and object.
25
“Comet Tail” “Ringdown”
Seldinger wire a few millimetres above its
entry to the jugular vein.
Reusz G et al. Br. J. Anaesth. 2014;112:794-802
Š The Author [2014]. Published by Oxford University Press on
behalf of the British Journal of Anaesthesia. All rights
reserved. For Permissions, please email:
journals.permissions@oup.com
Reverberations within a biopsy needle.
Schwartz DB, Zwiebel WJ, Zagzebski JA, Arbogast AL. ”Use of
real-time ultrasound to enhance fetoscopic visualization,” J Clinical
Ultrasound. 11(3): 161-164 (1983).
“Comet Tail” Artifacts (a reverberation phenomenon)
Ringdown Artifacts
(a reverberation phenomenon)
Water couple a transducer to a
phantom; then withdraw the
probe from the phantom
surface. Effect is as shown on
the right.
Ringdown Artifacts
(a reverberation phenomenon)
Water couple a transducer to a
phantom; then withdraw the
probe from the phantom
surface. Effect is as shown on
the right.
Repeat the experiment after
adding detergent to the water.
Bubbles result in a “ringing”
artifact.
This is the origin of what has
come to be known as
“ringdown artifacts.
Ringdown Artifacts
(a reverberation phenomenon)
Water couple a transducer
to a phantom; then
withdraw the probe from
the phantom surface. Effect
is as shown on the right.
Repeat the experiment after
adding detergent
Phased Array (Bubbles result in a “ringing” artifact) Linear Array
Ringdown Artifacts
(a reverberation phenomenon)
http://www.criticalecho.com/conte
nt/tutorial-1-basic-physics-
ultrasound-and-doppler-
phenomenon
What 2 factors are
combined on this B-mode
image? (Hint, 1 is an
artifact, the other involves
acquisition/processing.)
20%
20%
20%
20%
20% 1. Specular reflection angle effects and harmonic imaging
2. Specular refection angle effects and speckle reduction
3. Ring down and Spatial compound imaging
4. Reverberations and harmonic imaging
5. Shadowing and spatial compounding
10
Reverberation Artifacts
Veterinary Radiology & Ultrasound Volume 51, Issue 6, pages 621-627, 4 NOV 2010
DOI: 10.1111/j.1740-8261.2010.01724.x
http://onlinelibrary.wiley.com/doi/10.1111/j.1740-8261.2010.01724.x/full#f3
Ring-down artifacts from the stomach imaged with both conventional
(A and C) and spatial compound imaging (B and D)
Answer 3: Ringdown artifacts viewed with Spatial compound imaging
These 2 images of the bladder are identical, except one uses multiple transmit
focal zones (left) while the other does not (right). The most likely cause of the
echogenic region in the lower half of the bladder on the left is: (Hint, multiple
transmit zones often result in an elevated PRF.)
20%
20%
20%
20%
20% 1. Reverberations
2. Range ambiguity
3. Beam width artifacts
4. Mirror image artifacts
5. Speed of sound artifacts
10
Scan courtesy of Dr. Stephen
Thomas, Dept of Radiology,
University of Chicago.
Answer 2: Range ambiguity artifact RT O’Brien, JA Zagzebski, FA Delaney, Range
ambiguity artifacts, Vet Radiology & Ultrasound 42: 542-545, 2001.
Echo signals, artifacts, acoustic noise from “beam n” arizing beyond the
FOV are detected; if PRF is too high, they are picked up after transmitting
along beam n + 1.)
Beam n
Beam n + 1
Time (beam n)
Time (beam n + 1)
Reverb from bottom of
phantom, beam n
Echo
signal
1/PRF
“Specular Reflection” vs Scatter
• Scatter helps visualize
normal structures.
• Scatter helps visualize
abnormal structures.
35
Liver Hemangioma visualized because of
scatter changes w/normal tissue
Speckle
JA Zagzebski, Essentials of Ultrasound Physics, Mosby, St Louis, 1996. Chapter 7.
Gray Scale Texture, “Speckle”
• Each dot we see on the image does not represent a single
scatterer.
• Each dot is the result of echo signals simultaneously
detected from many scatterers insonified by the pulse.
• “Interference” effects help create the dot pattern.
– Signals from individual scattering entities reinforce, partially
cancel, or completely cancel, depending on their relative phases.
• Most consider this a noise phenomenon.
• Spatial compounding combines “views” of the scattering
field from different directions; reduces speckle.
• Some manufacturers are taking measures to reduce
speckle.
38
Image of a phantom, showing speckle
(Philips Ultrasound) 39
Spatially Compound image of a phantom, showing reduced speckle
(Philips Ultrasound) 40
Speckle Reduction Imaging (SRI)
By Coherent Diffusion
Algorithm Adapts Based on Image Feature; if statistical test results for a pixel region
are consistent with the area being “speckle”, smoothing is done. If there are
specular-type interfaces, the original data are maintained.
(GE Medical)
41
GE’s SRI (Speckle Reduction Imaging)
Different levels of “filtering”
42
Speed of Sound Artifacts
43
Speed of Sound Artifacts
44
Kremkau FW, Taylor KJ., “Artifacts in ultrasound imaging,” J
Ultrasound Med. 1986 Apr;5(4):227-37.
Speed of Sound Artifacts
Muscle SOS = 1560 m/s
Cartilage
SOS = 2500 m/s
The soft tissue-to-lung interface (arrow)
should appear straight, but the higher SOS in
the cartilage results in the interface
appearing curved.
45
Therapy planning and monitoring
Fontanarosa D, van der Meer S, Bloemen-van Gurp E, “Magnitude of speed of sound
aberration corrections for ultrasound image guided radiotherapy for prostate and other
anatomical sites.” Med. Phys. 2012; 39 (8): 5286-92.
• Superimposed CT
and Ultrasound
image, after
correcting for SOS
effects.
• “Density based
correction”
• Each pixel along
each beam line is
shifted according
to new SOS
estimations based
on CT density.
Therapy planning and monitoring
• Superimposed CT
and Ultrasound
image, after
correcting for SOS
effects.
• “Density based
correction”
• Each pixel along
each beam line is
shifted according
to new SOS
estimations based
on CT density.
Fontanarosa D, van der Meer S, Bloemen-van Gurp E, “Magnitude of speed of sound
aberration corrections for ultrasound image guided radiotherapy for prostate and other
anatomical sites.” Med. Phys. 2012; 39 (8): 5286-92.
Mast T, “Empirical relationship between acoustic parameters in
human soft tissues.” Acoustics Research Letters online, 2000; 1:37.
Fat, Adipose
Muscle, Connective
Therapy planning and monitoring
• Typical results for prostate, using the
shift of the centroid of the target as a
metric:
1p -1.3 mm
2p -3.6 mm
3p -3.1mm
4p -3.3 mm
5p -2.8 mm
Average shift, -2.8 mm
• “… a larger apparent depth of the
prostate is produced by the SOS
aberration, with different
magnitudes according to the relative
importance of the amount of fat
tissue and urine content in the
bladder [1520 m/s with respect to
muscle tissue [1580 m/s overlying
the prostate.”
Fontanarosa D, van der Meer S, Bloemen-van Gurp E, “Magnitude of speed of sound
aberration corrections for ultrasound image guided radiotherapy for prostate and other
anatomical sites.” Med. Phys. 2012; 39 (8): 5286-92.
Sound Speed Correction
1.48 mm/msec ATS Phantom Imaged at 1.54 mm/msec
(Courtesy of Larry Mo, Zonare Corp.)
Zonare allows the machine to
change the assumed SOS in the
beamformer in order to optimize
the sharpness. Notive here the SOS
in the phantom is 1480 m/s while
the machine assumes 1540 m/s in
the beamformer.
49
Sound Speed Correction
1.48 mm/msec ATS Phantom Imaged at 1.48 mm/msec
Image Rescaled to 1.54 mm/msec Dimensions
(Courtesy of Larry Mo, Zonare Corp.)
Zonare allows the machine to
change the assumed SOS in the
beamformer in order to optimize
the sharpness. Here the SOS in the
phantom is 1480 m/s and the
machine assumes 1480 m/s in the
beamformer.
50
Sound Speed Correction
8.5 MHz Breast Image at 1.54 mm/msec
Average Patient
(Courtesy of Larry Mo, Zonare Corp.)
Zonare allows the machine to
change the assumed SOS in the
beamformer in order to optimize
the sharpness. Here the SOS in the
tissue is unknown, yet the machine
assumes 1540 m/s in the
beamformer.
51
Sound Speed Correction
Image Rescaled to 1.54 mm/msec Dimensions
8.5 MHz Breast Image at 1.44 mm/msec
Average Patient
(Courtesy of Larry Mo, Zonare Corp.)
Zonare allows the machine to
change the assumed SOS in the
beamformer in order to optimize
the sharpness. Here the SOS in the
tissue is unknown, but the best
image is achieved when the
machine assumes 1440 m/s in the
beamformer.
Many scanners now employ
application specific presets where a
lower SOS is assumed along at least
part of the path.
52
Another artifact: Scan an ATS 539 Phantom
53
1. Echo from surface of object
2. Echo from strong reflector
3. Echo from object produced by 2
4. 3 reflected by strong reflector
Use a Larger FOV: Mirror Image Artifacts
54
1. Echo from surface of object
2. Echo from strong reflector
3. Echo from object produced by 2
4. 3 reflected by strong reflector
Mirror Image Artifacts
55
1. Echo from surface of object
2. Echo from strong reflector
3. Echo from object produced by 2
4. 3 reflected by strong reflector
Mirror Image Artifacts
56
http://www.criticalecho.com/content/tutorial-1-basic-
physics-ultrasound-and-doppler-phenomenon
Still, calm Colorado River, canyon, and mirrored canyon.
Mirroring can be side-to-side
57
Side wall of Gammex 403 phantom is the mirror
This B-mode image obtained with
a transvaginal transducer,
illustrates an early pregnancy
(arrow). It also presents an
interesting example of what type
of artifact? (red arrow)
20%
20%
20%
20%
20% 1. Side lobe
2. Attenuation
3. Mirror image
4. Reverberations
5. Speed of sound
10
Mirror-Image Artifact of Early Pregnancy on Transvaginal
Sonography
JUM November 1, 2012 vol. 31 no. 11 1858-1859
Imaging done with a tightly curved curvilinear
transducer (note, this image is oriented properly)
Mirror image
Actual fetal sac
Answer 3: Mirror image
Mirror Image Artifact (Spectral Doppler)
Mirror Image Artifacts in Doppler:
- being ~ perpendicular to flow;
- using too high a gain
- dead transducer elements(?) 60
Flow in this carotid artery is right-to-left.
However, it appears bi-directional.
Mirror Image Artifact (color)
• Inferior vena cava
• “extra” vessel
• Mirror is the
diaphragm in this
case.
61
Pozniak, M, Zagzebski, J and Scanlan, K, “Spectral and Color Doppler Artifacts,”
Radiographics12, 35-44, 1992.
PW Doppler Processing and Spectral Display
Sensitive to the changing phase of the returning echo signals
Time
Doppler
Frequency
c
cosθ
v
2f
F o
D 
Doppler Frequency
Time
1 sec









cosθ
2f
c
F
v
o
D
PW Doppler Processing and Spectral Display
With proper “angle correct”, can display as a velocity vs. time
Blood Velocity
Time
1 sec
This Doppler signal waveform is inadequate, mainly because of
which artifact?
20%
20%
20%
20%
20% 1. Aliasing
2. Speckle
3. Ring down
4. Speed of sound
5. Spectral mirroring
10
Blood Velocity
1 sec
Doppler Signal Formation with PW Doppler
(Sampling at the PRF)
1. Doppler mode pulses transmitted along
a “Doppler beam line”
2. Operator selects location, gate size of a
“sample volume”
3. Doppler signal (yellow signal curve for
example) from this volume is generated
through a “sampling” process
 ie, shown here with the white arrows
4. The sample rate equals the pulse
repetition frequency (PRF)!
Answer 1: Aliasing
JA Zagzebski, Essentials of Ultrasound Physics,
Mosby, St Louis, 1996. Chapter 5.
Arrows represent
sampling times
Ideal signal
Sampled result
Aliasing occurs if the Doppler
frequency exceeds ½ the PRF.
Manifestation of Aliasing
PRF
Velocity scale
PRF
Velocity scale
After increasing the Velocity Scale (or the PRF)
PRF
Velocity scale
To get rid of aliasing:
• Change the
velocity scale
• Change the
baseline
• Use a lower
ultrasound
frequency
This image illustrates an example of:
20%
20%
20%
20%
20% 1. Aliasing
2. Spectral mirroring
3. Poor Doppler angle
4. Erroneous angle correct
5. Too low a PW ultrasonic frequency
10
Apparent
Peak Velocity
22 cm/s
The angle correct is established by the sonographer. The erroneous
setting in the previous case resulted in an apparent peak velocity of 22
cm/s.
With the correct setting, the peak velocity appears to be ~110 cm/s.
Apparent
Peak Velocity
110 cm/s
Answer 4: Erroneous angle correct
JA Zagzebski, Essentials of Ultrasound Physics, Mosby, St Louis, 1996. Chapter 5.
This image of a hepatic vein
suggests bi-directional flow (arrow)
just below the gall bladder. This is a
clear manifestation of:
20%
20%
20%
20%
20% 1. A dissection
2. The US frequency set too low
3. A stenosis
4. Aliasing
5. The color gain set too high
10
Answer 4, Aliasing
Color flow imaging is based on pulsed
Doppler principles. Aliasing occurs if the
Doppler frequency exceeds ½ the PRF,
and results in a wrapping around on the
color scale.
This is an image of the same structure
after the velocity scale was increased
from +12 cm/s to +21 cm/s, and the PRF
was increased from 0.6 kHz to 1.0 kHz.
Scan courtesy of Dr. David Paushter, Dept
of Radiology, University of Chicago.
This B-mode image (left) and color flow image (right) shows a urinary
bladder. The color image on the right exhibits an artifact (arrows)
known as:
20%
20%
20%
20%
20% 1. twinkling
2. aliasing
3. overgaining
4. enhancement
5. color bleeding
10
• Answer 1, twinkling
• The twinkle artifact is
associated with calcifications,
stones, and other rough
objects. It has been attributed
to system clock jitter, noise, and
even bubbles.
• (Mitchell C, Pozniak M, Zagzebski J,
Ledwidge M. “Twinkling artifact related
to intravascular suture.” J Ultrasound
Med 22:1409–1411, 2003.)
A point-like reflector will result in a line on the image; the length of the line equals the
beam width at the depth of the reflector.
76
Beam Width Artifacts
Single element
transducer
Beam is wide here
Focal zone; beam is
narrow
Beam is wide here
77
Receive
focusing off
Transmit focusing applied to a
single depth
Receive focusing is disabled
Transmit Focusing Only
Receive
focusing on
Transmit focusing applied to a
single depth
Receive focusing done in the
“beam former”
- Uses time delays
- Changes dynamically
Dynamic Receive Focusing
80
20%
20%
20%
20%
20% 1. Reverberation
2. Refraction
3. Speed of sound
4. Beam width
5. Slice thickness
10
This image is of a phantom that
contains 4 mm diameter
spherical, low scatter objects.
The objects are not visualized
over the first 4 .5 cm (see
image). This is due to
___________ effects.
Slice thickness is large
here
Elevational focal
zone
Slice thickness is large
here
82
Answer 5, Slice thickness effects.
JA Zagzebski, Essentials of Ultrasound Physics, Mosby, St Louis, 1996. Chapter 2.
Conventional
Transducer
“1 ½ D”
Transducer
Conventional
Transducer
1 ½ D
Transducer
Grating Lobes (array transducers)
85
86
87
88
89
Example of side lobe, grating lobe
90
Courtesy of Douglas Pfeiffer,
Boulder Community Foothills Hospital
Effects of side/grating lobes from a damaged curvilinear
transducer. This image shows a section (red) of an ATS
539 phantom.
Brighter, or “enhanced” echo
signals are seen in this image
below the echo free mass. This is
a result of:
20%
20%
20%
20%
20% 1. Improper TGC settings
2. Lower density in the mass
3. Lower attenuation in the mass
4. Higher speed of sound in the mass
5. Lower acoustic impedance of the mass
10
Answer 3: Lower attenuation in the mass introduces “echo enhancement”
Attenuation Artifacts (useful)
93
JA Zagzebski, Essentials of Ultrasound Physics, Mosby, St Louis, 1996. Chapter 7.
Attenuation Artifacts (useful)
Enhancement
(Attenuation in a cyst is lower than in
surrounding tissue)
Shadowing
(Attenuation in mass is greater
than that in surrounding tissue)
94
Refraction Effects
95
Refraction Effects
96
Refraction Effects
97
Buttery B, Davison G. “The ghost artifact,”
J Ultrasound Med. 1984 Feb;3(2):49-52.
Which one of the following will
reduce reverberation artifacts
10
20%
20%
20%
20%
20% 1. Apply compound imaging
2. Use coded excitation
3. Use harmonic imaging
4. Use a low transmit power
5. Avoid using curvilinear arrays
Recap:
Answer 3: Harmonic Imaging
It will at least partially help. Usually do not get the
dramatic results as seen in these 2 images.
99
.
Entrekin RR1, Porter BA, Sillesen HH, Wong AD, Cooperberg PL. “ Real-time spatial compound
imaging: application to breast, vascular, and musculoskeletal ultrasound.” Semin Ultrasound CT
MR. 2001 Feb;22(1):50-64
100
Answer 3: Harmonic Imaging
It will at least partially help. Usually do not get the
dramatic results as seen in these 2 images. Typical:
UW Archives
Coded Excitation
Decoder
(matched filter)
• Sensitivity Increase
Encoder
Coded Excitation improves sensitivity
without resolution tradeoff
Body
1 1 1 0 1 0 1 1
Transmitted Pulse Train
Received Pulse Train
1 1 0 1 0 1 1 1
Richard Chiao, Ph.D.
GE Medical Systems
Courtesy of GE Ultrasound
This is an image of a tissue-like
phantom containing an inclusion.
The bottom of the phantom
exhibits a discontinuity in the
region beneath the inclusion. The
inclusion appears to have a
______ than the phantom
material.
10
20%
20%
20%
20%
20% 1. Greater density
2. Lower attenuation
3. Higher attenuation
4. Lower speed of sound
5. Higher speed of sound
Recap:
TM Gel
Inclusion
Speed of Sound Artifacts
TM Gel SOS = 1560 m/s
The interface (arrow) should appear straight,
but the lower SOS in the silicon results in the
interface appearing curved and distorted.
103
Answer 4, Lower speed of
sound, causing the bottom
of the phantom to appear
displaced downward in the
B-mode image.
TM Gel SOS = 1560 m/s
Silicon Droplet
SOS = 1200 m/s
H Lopez, K M Harris “Ultrasound interactions with free silicone in a tissue-mimicking
phantom. “ J Ultrasound Med 17: 163-170, 1998.
Shadowing and enhancement
(right) artifacts are most closely
related to spatial variations in
10
20%
20%
20%
20%
20% 1. Attenuation
2. Organ shape
3. Acoustical impedance
4. Speed of sound
5. Echogenicity
Recap:
Answer 1
Shadowing and enhancement
artifacts are most closely related to
spatial variations in attenuation.
The gall bladder (GB) is fluid filled,
and the attenuation coefficient of
bile is lower than that of
surrounding tissue. This results in
higher amplitude echo signals from
distal to the GB.
GB
JA Zagzebski, Essentials of Ultrasound Physics, Mosby, St Louis, 1996. Chapter 7.
To best visualize shadowing and enhancement
features of breast masses, sonographers are
advised to avoid use of _________.
10
20%
20%
20%
20%
20% 1. Harmonic imaging
2. Time gain compensation
3. Speckle reduction
4. Compound imaging
5. High ultrasound frequencies
Recap:
Answer: d – compound imaging.
Ref: ACR Breast Ultrasound Accreditation Program Testing
Instructions. American College of Radiology, Reston, VA.
12014. Page 2.
(Supposedly, for small masses that are shallow, it might
hide the shadowing and enhancement artifacts. )
Final Artifact: Difficulties scanning (flat window)
phantoms with curvilinear array transducers.
403 GS phantom
Gel coupling
Detecting damaged transducers is the most important QA task.
Can only make contact with part of curved probes
Solution 1, with gel coupling, rock transducer
Artifacts when scanning (flat window) phantoms with
curvilinear array transducers using water dam.
410 GS phantom
Solution 2: use a phantom with a curved window
Artifacts when scanning (flat window) phantoms with
curvilinear array transducers using water dam.
403 GS phantom
Solution 2: use a phantom with a curved window
(but most of us have flat window phantoms)
Solution 3: use water in the water dam (bad artifacts!)
Artifacts are totally removed using whole milk.
403 GS phantom
Grade A Homogenized milk;
(SOS ~1525-30m/s; sufficient attenuation to cut down
spurious echoes )
Solution 4: use milk in the water dam!!!
403 GS phantom
Thanks, from America’s Dairyland, and the Land of
Lincoln Solution 1: rock the transducer
Solution 2: use a phantom with a curved window
Solution 2: use water in the dam (bad artifacts with curved probes
Solution 4: use milk in the water dam

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Reverberation Artifacts in ultrasound imaging

  • 1. Art of Imaging: Diagnostic Ultrasound Image Artifacts James A. Zagzebski, Ph.D., Department of Medical Physics, University of Wisconsin – Madison Zheng Feng Lu, Ph.D., Department of Radiology, University of Chicago AAPM Meeting July 20-24, 2014, Austin Texas
  • 2. Introduction • Underlying assumptions when forming B-mode images • Artifacts for specular reflectors • Reverberations • Scatter effects, speckle, speckle reduction • Mirror image artifacts • Common artifacts in Doppler • Refraction • Attenuation, shadowing, enhancement
  • 3. For those with “SAMs” audience response clickers, Trial question: Illinois is known as the “Land of Lincoln;” Wisconsin is called “________.” 20% 20% 20% 20% 20% 1. The Beehive State 2. America’s Dairyland 3. The Coyote state 4. The Beaver State 5. The Lone Star State 10
  • 4. 1. The Beehive State (Utah) 2. America’s Dairyland (Wisconsin) 3. The Coyote state (S. Dakota; officially, Mt Rushmore state) 4. The Beaver State (Oregon) 5. The Lone Star State (Texas) Answer 2 America’s Dairyland ( http://en.wikipedia.org/wiki/List_of_U.S._state_nicknames )
  • 5. Echo Arrival Time Underlying Assumptions when forming images: (Assumes a Sound Speed, usually 1,540 m/s)
  • 6. Direct “beams” over scanned region 150-200 “acoustic scan lines” (beam lines) 25-50 sweeps/s Pulse repetition frequency of about 25 x 200 = 4,000 /s Dots representing echo signals are displayed along a line that represents the ultrasound beam axis. Location along the line depends on echo arrival times. Underlying Assumptions when forming images:
  • 7. Dot brightness represents the echo signal amplitude. Try to optimize TGC, etc., so this indicates relative reflectivity. Underlying Assumptions when forming images:
  • 8. Which of the following is NOT assumed implicitly during the formation of a conventional ultrasound B- mode image? 20% 20% 20% 20% 20% 1. echoes originate from along “beam” axes 2. wave speed is 1540 m/s 3. brightness indicates reflectivity level 4. speckle reveals microscopic details of scatterers 5. TGC corrects for attenuation throughout 10
  • 9. B-mode Imaging Assumptions • Pulse-echo transit times can be converted to reflector depth through uniform tissue models. • Echoes originate (only) from locations along the transmit-receive axes of pulse propagation path. • First order correction schemes (such as TGC) adequately account for acoustic wave attenuation and absorption. • Display brightness encodes tissue echogenicity. Answer 4: “speckle reveals microscopic details of scatterers” is not an assumption. JA Zagzebski, Essentials of Ultrasound Physics, Mosby, St Louis, 1996. Chapter 7. F Kremkau, Chapter 6 in Textbook of Diagnostic Sonography, SL Hagen Ansert, Elsevier, 2012, Chapter 6.
  • 10. Echoes from the superior pole of the kidney are weaker (do not appear as bright) than those from the proximal surface because of changes in ____ over the liver-kidney interface. 20% 20% 20% 20% 20% 1. Beam focusing 2. frequency 3. acoustic impedance 4. depth 5. incident beam angle 10
  • 11. Answer 5: changes in incident beam angle Specular Reflector: effects on ability to outline an object 11 Impedance change at liver-to-kidney interface likely is uniform Beams from a curvilinear array emerge perpendicular to surface of aperture Strong effects of beam angle on detected amplitude, display brightness JA Zagzebski, Essentials of Ultrasound Physics, Mosby, St Louis, 1996. Chapter 7.
  • 12. Spatial Compounding  Uses “beam steering” technology  Combines scans from different angles  More completely outlines interfaces that are not perpendicular to primary beam direction  Smoothes random dots called speckle
  • 13. Š 2000 ATL Ultrasound . Entrekin RR1, Porter BA, Sillesen HH, Wong AD, Cooperberg PL. “ Real-time spatial compound imaging: application to breast, vascular, and musculoskeletal ultrasound.” Semin Ultrasound CT MR. 2001 Feb;22(1):50-64
  • 14. 20% 20% 20% 20% 20% 1. A focal mass 2. Higher speed of sound in this region 3. Side lobe artifacts 4. Reverberations 5. Stress from a swollen kidney 10 The region of brighter echoes in this longitudunal view of the liver and kidney are most likely due to which of the following? Focal brightness
  • 15. Images of a Gammex 403 Phantom Transducer in direct contact 12 mm tissue-like layer between the transducer and the phantom Answer 4: Reverberations (likely, the most ubiquitous ultrasound artifact) JA Zagzebski, Essentials of Ultrasound Physics, Elsevier, 1996. FW Kremkau, Sonography Principles and Instruments,, Elsevier, 2011.
  • 17. Reverberation Artifacts Air bubble in a water-filled condom. 17
  • 18. Reverberations Reverberations here Produce “noise” here 18 . Entrekin RR1, Porter BA, Sillesen HH, Wong AD, Cooperberg PL. “ Real-time spatial compound imaging: application to breast, vascular, and musculoskeletal ultrasound.” Semin Ultrasound CT MR. 2001 Feb;22(1):50-64
  • 19. Reverberations Reverberations here Produce “noise” here 19 . Entrekin et al, Semin Ultrasound CT MR. 2001 Feb;22(1):50-64
  • 20. Reverberations Park et al, “Introperative Contrast –enhanced sonographic …,” J Ultrasound Med 35(7): 1287-91, 2014. Donadon & Torzilli, Am J Roent,198(4): April, 2012. MedlinePlus, 2012 Reverbs Body wall No Reverbs Fundamental problem: must transmit through tissue layers Ideal(??)
  • 21. Harmonic Imaging Transmit a low-frequency pulse (2-5 MHz) The pulse gradually distorts due to nonlinear propagation  second harmonic generation Harmonic field is weaker than fundamental as incident beam propagates through superficial layers 21 . Entrekin et al, Semin Ultrasound CT MR. 2001 Feb;22(1):50-64
  • 23. Reverbs weak Harmonic Beam HarmonicBeam (increases as depth increases) 23
  • 24. “Clarify” (Siemens Medical Solutions) Uses power Doppler signals to remove unwanted gray scale echo signals from vessels. Doppler flow phantom After applying Clarify
  • 25. Reverberation Artifacts Examples of reverberations occurring within distal objects, not back and forth between transducer and object. 25 “Comet Tail” “Ringdown”
  • 26. Seldinger wire a few millimetres above its entry to the jugular vein. Reusz G et al. Br. J. Anaesth. 2014;112:794-802 Š The Author [2014]. Published by Oxford University Press on behalf of the British Journal of Anaesthesia. All rights reserved. For Permissions, please email: journals.permissions@oup.com Reverberations within a biopsy needle. Schwartz DB, Zwiebel WJ, Zagzebski JA, Arbogast AL. ”Use of real-time ultrasound to enhance fetoscopic visualization,” J Clinical Ultrasound. 11(3): 161-164 (1983). “Comet Tail” Artifacts (a reverberation phenomenon)
  • 27. Ringdown Artifacts (a reverberation phenomenon) Water couple a transducer to a phantom; then withdraw the probe from the phantom surface. Effect is as shown on the right.
  • 28. Ringdown Artifacts (a reverberation phenomenon) Water couple a transducer to a phantom; then withdraw the probe from the phantom surface. Effect is as shown on the right. Repeat the experiment after adding detergent to the water. Bubbles result in a “ringing” artifact. This is the origin of what has come to be known as “ringdown artifacts.
  • 29. Ringdown Artifacts (a reverberation phenomenon) Water couple a transducer to a phantom; then withdraw the probe from the phantom surface. Effect is as shown on the right. Repeat the experiment after adding detergent Phased Array (Bubbles result in a “ringing” artifact) Linear Array
  • 30. Ringdown Artifacts (a reverberation phenomenon) http://www.criticalecho.com/conte nt/tutorial-1-basic-physics- ultrasound-and-doppler- phenomenon
  • 31. What 2 factors are combined on this B-mode image? (Hint, 1 is an artifact, the other involves acquisition/processing.) 20% 20% 20% 20% 20% 1. Specular reflection angle effects and harmonic imaging 2. Specular refection angle effects and speckle reduction 3. Ring down and Spatial compound imaging 4. Reverberations and harmonic imaging 5. Shadowing and spatial compounding 10
  • 32. Reverberation Artifacts Veterinary Radiology & Ultrasound Volume 51, Issue 6, pages 621-627, 4 NOV 2010 DOI: 10.1111/j.1740-8261.2010.01724.x http://onlinelibrary.wiley.com/doi/10.1111/j.1740-8261.2010.01724.x/full#f3 Ring-down artifacts from the stomach imaged with both conventional (A and C) and spatial compound imaging (B and D) Answer 3: Ringdown artifacts viewed with Spatial compound imaging
  • 33. These 2 images of the bladder are identical, except one uses multiple transmit focal zones (left) while the other does not (right). The most likely cause of the echogenic region in the lower half of the bladder on the left is: (Hint, multiple transmit zones often result in an elevated PRF.) 20% 20% 20% 20% 20% 1. Reverberations 2. Range ambiguity 3. Beam width artifacts 4. Mirror image artifacts 5. Speed of sound artifacts 10 Scan courtesy of Dr. Stephen Thomas, Dept of Radiology, University of Chicago.
  • 34. Answer 2: Range ambiguity artifact RT O’Brien, JA Zagzebski, FA Delaney, Range ambiguity artifacts, Vet Radiology & Ultrasound 42: 542-545, 2001. Echo signals, artifacts, acoustic noise from “beam n” arizing beyond the FOV are detected; if PRF is too high, they are picked up after transmitting along beam n + 1.) Beam n Beam n + 1 Time (beam n) Time (beam n + 1) Reverb from bottom of phantom, beam n Echo signal 1/PRF
  • 35. “Specular Reflection” vs Scatter • Scatter helps visualize normal structures. • Scatter helps visualize abnormal structures. 35
  • 36. Liver Hemangioma visualized because of scatter changes w/normal tissue
  • 37. Speckle JA Zagzebski, Essentials of Ultrasound Physics, Mosby, St Louis, 1996. Chapter 7.
  • 38. Gray Scale Texture, “Speckle” • Each dot we see on the image does not represent a single scatterer. • Each dot is the result of echo signals simultaneously detected from many scatterers insonified by the pulse. • “Interference” effects help create the dot pattern. – Signals from individual scattering entities reinforce, partially cancel, or completely cancel, depending on their relative phases. • Most consider this a noise phenomenon. • Spatial compounding combines “views” of the scattering field from different directions; reduces speckle. • Some manufacturers are taking measures to reduce speckle. 38
  • 39. Image of a phantom, showing speckle (Philips Ultrasound) 39
  • 40. Spatially Compound image of a phantom, showing reduced speckle (Philips Ultrasound) 40
  • 41. Speckle Reduction Imaging (SRI) By Coherent Diffusion Algorithm Adapts Based on Image Feature; if statistical test results for a pixel region are consistent with the area being “speckle”, smoothing is done. If there are specular-type interfaces, the original data are maintained. (GE Medical) 41
  • 42. GE’s SRI (Speckle Reduction Imaging) Different levels of “filtering” 42
  • 43. Speed of Sound Artifacts 43
  • 44. Speed of Sound Artifacts 44 Kremkau FW, Taylor KJ., “Artifacts in ultrasound imaging,” J Ultrasound Med. 1986 Apr;5(4):227-37.
  • 45. Speed of Sound Artifacts Muscle SOS = 1560 m/s Cartilage SOS = 2500 m/s The soft tissue-to-lung interface (arrow) should appear straight, but the higher SOS in the cartilage results in the interface appearing curved. 45
  • 46. Therapy planning and monitoring Fontanarosa D, van der Meer S, Bloemen-van Gurp E, “Magnitude of speed of sound aberration corrections for ultrasound image guided radiotherapy for prostate and other anatomical sites.” Med. Phys. 2012; 39 (8): 5286-92. • Superimposed CT and Ultrasound image, after correcting for SOS effects. • “Density based correction” • Each pixel along each beam line is shifted according to new SOS estimations based on CT density.
  • 47. Therapy planning and monitoring • Superimposed CT and Ultrasound image, after correcting for SOS effects. • “Density based correction” • Each pixel along each beam line is shifted according to new SOS estimations based on CT density. Fontanarosa D, van der Meer S, Bloemen-van Gurp E, “Magnitude of speed of sound aberration corrections for ultrasound image guided radiotherapy for prostate and other anatomical sites.” Med. Phys. 2012; 39 (8): 5286-92. Mast T, “Empirical relationship between acoustic parameters in human soft tissues.” Acoustics Research Letters online, 2000; 1:37. Fat, Adipose Muscle, Connective
  • 48. Therapy planning and monitoring • Typical results for prostate, using the shift of the centroid of the target as a metric: 1p -1.3 mm 2p -3.6 mm 3p -3.1mm 4p -3.3 mm 5p -2.8 mm Average shift, -2.8 mm • “… a larger apparent depth of the prostate is produced by the SOS aberration, with different magnitudes according to the relative importance of the amount of fat tissue and urine content in the bladder [1520 m/s with respect to muscle tissue [1580 m/s overlying the prostate.” Fontanarosa D, van der Meer S, Bloemen-van Gurp E, “Magnitude of speed of sound aberration corrections for ultrasound image guided radiotherapy for prostate and other anatomical sites.” Med. Phys. 2012; 39 (8): 5286-92.
  • 49. Sound Speed Correction 1.48 mm/msec ATS Phantom Imaged at 1.54 mm/msec (Courtesy of Larry Mo, Zonare Corp.) Zonare allows the machine to change the assumed SOS in the beamformer in order to optimize the sharpness. Notive here the SOS in the phantom is 1480 m/s while the machine assumes 1540 m/s in the beamformer. 49
  • 50. Sound Speed Correction 1.48 mm/msec ATS Phantom Imaged at 1.48 mm/msec Image Rescaled to 1.54 mm/msec Dimensions (Courtesy of Larry Mo, Zonare Corp.) Zonare allows the machine to change the assumed SOS in the beamformer in order to optimize the sharpness. Here the SOS in the phantom is 1480 m/s and the machine assumes 1480 m/s in the beamformer. 50
  • 51. Sound Speed Correction 8.5 MHz Breast Image at 1.54 mm/msec Average Patient (Courtesy of Larry Mo, Zonare Corp.) Zonare allows the machine to change the assumed SOS in the beamformer in order to optimize the sharpness. Here the SOS in the tissue is unknown, yet the machine assumes 1540 m/s in the beamformer. 51
  • 52. Sound Speed Correction Image Rescaled to 1.54 mm/msec Dimensions 8.5 MHz Breast Image at 1.44 mm/msec Average Patient (Courtesy of Larry Mo, Zonare Corp.) Zonare allows the machine to change the assumed SOS in the beamformer in order to optimize the sharpness. Here the SOS in the tissue is unknown, but the best image is achieved when the machine assumes 1440 m/s in the beamformer. Many scanners now employ application specific presets where a lower SOS is assumed along at least part of the path. 52
  • 53. Another artifact: Scan an ATS 539 Phantom 53 1. Echo from surface of object 2. Echo from strong reflector 3. Echo from object produced by 2 4. 3 reflected by strong reflector
  • 54. Use a Larger FOV: Mirror Image Artifacts 54 1. Echo from surface of object 2. Echo from strong reflector 3. Echo from object produced by 2 4. 3 reflected by strong reflector
  • 55. Mirror Image Artifacts 55 1. Echo from surface of object 2. Echo from strong reflector 3. Echo from object produced by 2 4. 3 reflected by strong reflector
  • 57. Mirroring can be side-to-side 57 Side wall of Gammex 403 phantom is the mirror
  • 58. This B-mode image obtained with a transvaginal transducer, illustrates an early pregnancy (arrow). It also presents an interesting example of what type of artifact? (red arrow) 20% 20% 20% 20% 20% 1. Side lobe 2. Attenuation 3. Mirror image 4. Reverberations 5. Speed of sound 10
  • 59. Mirror-Image Artifact of Early Pregnancy on Transvaginal Sonography JUM November 1, 2012 vol. 31 no. 11 1858-1859 Imaging done with a tightly curved curvilinear transducer (note, this image is oriented properly) Mirror image Actual fetal sac Answer 3: Mirror image
  • 60. Mirror Image Artifact (Spectral Doppler) Mirror Image Artifacts in Doppler: - being ~ perpendicular to flow; - using too high a gain - dead transducer elements(?) 60 Flow in this carotid artery is right-to-left. However, it appears bi-directional.
  • 61. Mirror Image Artifact (color) • Inferior vena cava • “extra” vessel • Mirror is the diaphragm in this case. 61 Pozniak, M, Zagzebski, J and Scanlan, K, “Spectral and Color Doppler Artifacts,” Radiographics12, 35-44, 1992.
  • 62. PW Doppler Processing and Spectral Display Sensitive to the changing phase of the returning echo signals Time Doppler Frequency c cosθ v 2f F o D  Doppler Frequency Time 1 sec
  • 63.          cosθ 2f c F v o D PW Doppler Processing and Spectral Display With proper “angle correct”, can display as a velocity vs. time Blood Velocity Time 1 sec
  • 64. This Doppler signal waveform is inadequate, mainly because of which artifact? 20% 20% 20% 20% 20% 1. Aliasing 2. Speckle 3. Ring down 4. Speed of sound 5. Spectral mirroring 10 Blood Velocity 1 sec
  • 65. Doppler Signal Formation with PW Doppler (Sampling at the PRF) 1. Doppler mode pulses transmitted along a “Doppler beam line” 2. Operator selects location, gate size of a “sample volume” 3. Doppler signal (yellow signal curve for example) from this volume is generated through a “sampling” process  ie, shown here with the white arrows 4. The sample rate equals the pulse repetition frequency (PRF)! Answer 1: Aliasing JA Zagzebski, Essentials of Ultrasound Physics, Mosby, St Louis, 1996. Chapter 5.
  • 66. Arrows represent sampling times Ideal signal Sampled result Aliasing occurs if the Doppler frequency exceeds ½ the PRF.
  • 67. Manifestation of Aliasing PRF Velocity scale PRF Velocity scale
  • 68. After increasing the Velocity Scale (or the PRF) PRF Velocity scale
  • 69. To get rid of aliasing: • Change the velocity scale • Change the baseline • Use a lower ultrasound frequency
  • 70. This image illustrates an example of: 20% 20% 20% 20% 20% 1. Aliasing 2. Spectral mirroring 3. Poor Doppler angle 4. Erroneous angle correct 5. Too low a PW ultrasonic frequency 10 Apparent Peak Velocity 22 cm/s
  • 71. The angle correct is established by the sonographer. The erroneous setting in the previous case resulted in an apparent peak velocity of 22 cm/s. With the correct setting, the peak velocity appears to be ~110 cm/s. Apparent Peak Velocity 110 cm/s Answer 4: Erroneous angle correct JA Zagzebski, Essentials of Ultrasound Physics, Mosby, St Louis, 1996. Chapter 5.
  • 72. This image of a hepatic vein suggests bi-directional flow (arrow) just below the gall bladder. This is a clear manifestation of: 20% 20% 20% 20% 20% 1. A dissection 2. The US frequency set too low 3. A stenosis 4. Aliasing 5. The color gain set too high 10
  • 73. Answer 4, Aliasing Color flow imaging is based on pulsed Doppler principles. Aliasing occurs if the Doppler frequency exceeds ½ the PRF, and results in a wrapping around on the color scale. This is an image of the same structure after the velocity scale was increased from +12 cm/s to +21 cm/s, and the PRF was increased from 0.6 kHz to 1.0 kHz. Scan courtesy of Dr. David Paushter, Dept of Radiology, University of Chicago.
  • 74. This B-mode image (left) and color flow image (right) shows a urinary bladder. The color image on the right exhibits an artifact (arrows) known as: 20% 20% 20% 20% 20% 1. twinkling 2. aliasing 3. overgaining 4. enhancement 5. color bleeding 10
  • 75. • Answer 1, twinkling • The twinkle artifact is associated with calcifications, stones, and other rough objects. It has been attributed to system clock jitter, noise, and even bubbles. • (Mitchell C, Pozniak M, Zagzebski J, Ledwidge M. “Twinkling artifact related to intravascular suture.” J Ultrasound Med 22:1409–1411, 2003.)
  • 76. A point-like reflector will result in a line on the image; the length of the line equals the beam width at the depth of the reflector. 76
  • 77. Beam Width Artifacts Single element transducer Beam is wide here Focal zone; beam is narrow Beam is wide here 77
  • 78. Receive focusing off Transmit focusing applied to a single depth Receive focusing is disabled Transmit Focusing Only
  • 79. Receive focusing on Transmit focusing applied to a single depth Receive focusing done in the “beam former” - Uses time delays - Changes dynamically Dynamic Receive Focusing
  • 80. 80
  • 81. 20% 20% 20% 20% 20% 1. Reverberation 2. Refraction 3. Speed of sound 4. Beam width 5. Slice thickness 10 This image is of a phantom that contains 4 mm diameter spherical, low scatter objects. The objects are not visualized over the first 4 .5 cm (see image). This is due to ___________ effects.
  • 82. Slice thickness is large here Elevational focal zone Slice thickness is large here 82 Answer 5, Slice thickness effects. JA Zagzebski, Essentials of Ultrasound Physics, Mosby, St Louis, 1996. Chapter 2.
  • 85. Grating Lobes (array transducers) 85
  • 86. 86
  • 87. 87
  • 88. 88
  • 89. 89
  • 90. Example of side lobe, grating lobe 90
  • 91. Courtesy of Douglas Pfeiffer, Boulder Community Foothills Hospital Effects of side/grating lobes from a damaged curvilinear transducer. This image shows a section (red) of an ATS 539 phantom.
  • 92. Brighter, or “enhanced” echo signals are seen in this image below the echo free mass. This is a result of: 20% 20% 20% 20% 20% 1. Improper TGC settings 2. Lower density in the mass 3. Lower attenuation in the mass 4. Higher speed of sound in the mass 5. Lower acoustic impedance of the mass 10
  • 93. Answer 3: Lower attenuation in the mass introduces “echo enhancement” Attenuation Artifacts (useful) 93 JA Zagzebski, Essentials of Ultrasound Physics, Mosby, St Louis, 1996. Chapter 7.
  • 94. Attenuation Artifacts (useful) Enhancement (Attenuation in a cyst is lower than in surrounding tissue) Shadowing (Attenuation in mass is greater than that in surrounding tissue) 94
  • 97. Refraction Effects 97 Buttery B, Davison G. “The ghost artifact,” J Ultrasound Med. 1984 Feb;3(2):49-52.
  • 98. Which one of the following will reduce reverberation artifacts 10 20% 20% 20% 20% 20% 1. Apply compound imaging 2. Use coded excitation 3. Use harmonic imaging 4. Use a low transmit power 5. Avoid using curvilinear arrays Recap:
  • 99. Answer 3: Harmonic Imaging It will at least partially help. Usually do not get the dramatic results as seen in these 2 images. 99 . Entrekin RR1, Porter BA, Sillesen HH, Wong AD, Cooperberg PL. “ Real-time spatial compound imaging: application to breast, vascular, and musculoskeletal ultrasound.” Semin Ultrasound CT MR. 2001 Feb;22(1):50-64
  • 100. 100 Answer 3: Harmonic Imaging It will at least partially help. Usually do not get the dramatic results as seen in these 2 images. Typical: UW Archives
  • 101. Coded Excitation Decoder (matched filter) • Sensitivity Increase Encoder Coded Excitation improves sensitivity without resolution tradeoff Body 1 1 1 0 1 0 1 1 Transmitted Pulse Train Received Pulse Train 1 1 0 1 0 1 1 1 Richard Chiao, Ph.D. GE Medical Systems Courtesy of GE Ultrasound
  • 102. This is an image of a tissue-like phantom containing an inclusion. The bottom of the phantom exhibits a discontinuity in the region beneath the inclusion. The inclusion appears to have a ______ than the phantom material. 10 20% 20% 20% 20% 20% 1. Greater density 2. Lower attenuation 3. Higher attenuation 4. Lower speed of sound 5. Higher speed of sound Recap: TM Gel Inclusion
  • 103. Speed of Sound Artifacts TM Gel SOS = 1560 m/s The interface (arrow) should appear straight, but the lower SOS in the silicon results in the interface appearing curved and distorted. 103 Answer 4, Lower speed of sound, causing the bottom of the phantom to appear displaced downward in the B-mode image. TM Gel SOS = 1560 m/s Silicon Droplet SOS = 1200 m/s H Lopez, K M Harris “Ultrasound interactions with free silicone in a tissue-mimicking phantom. “ J Ultrasound Med 17: 163-170, 1998.
  • 104. Shadowing and enhancement (right) artifacts are most closely related to spatial variations in 10 20% 20% 20% 20% 20% 1. Attenuation 2. Organ shape 3. Acoustical impedance 4. Speed of sound 5. Echogenicity Recap:
  • 105. Answer 1 Shadowing and enhancement artifacts are most closely related to spatial variations in attenuation. The gall bladder (GB) is fluid filled, and the attenuation coefficient of bile is lower than that of surrounding tissue. This results in higher amplitude echo signals from distal to the GB. GB JA Zagzebski, Essentials of Ultrasound Physics, Mosby, St Louis, 1996. Chapter 7.
  • 106. To best visualize shadowing and enhancement features of breast masses, sonographers are advised to avoid use of _________. 10 20% 20% 20% 20% 20% 1. Harmonic imaging 2. Time gain compensation 3. Speckle reduction 4. Compound imaging 5. High ultrasound frequencies Recap:
  • 107. Answer: d – compound imaging. Ref: ACR Breast Ultrasound Accreditation Program Testing Instructions. American College of Radiology, Reston, VA. 12014. Page 2. (Supposedly, for small masses that are shallow, it might hide the shadowing and enhancement artifacts. )
  • 108. Final Artifact: Difficulties scanning (flat window) phantoms with curvilinear array transducers. 403 GS phantom Gel coupling Detecting damaged transducers is the most important QA task. Can only make contact with part of curved probes Solution 1, with gel coupling, rock transducer
  • 109. Artifacts when scanning (flat window) phantoms with curvilinear array transducers using water dam. 410 GS phantom Solution 2: use a phantom with a curved window
  • 110. Artifacts when scanning (flat window) phantoms with curvilinear array transducers using water dam. 403 GS phantom Solution 2: use a phantom with a curved window (but most of us have flat window phantoms) Solution 3: use water in the water dam (bad artifacts!)
  • 111. Artifacts are totally removed using whole milk. 403 GS phantom Grade A Homogenized milk; (SOS ~1525-30m/s; sufficient attenuation to cut down spurious echoes ) Solution 4: use milk in the water dam!!!
  • 112. 403 GS phantom Thanks, from America’s Dairyland, and the Land of Lincoln Solution 1: rock the transducer Solution 2: use a phantom with a curved window Solution 2: use water in the dam (bad artifacts with curved probes Solution 4: use milk in the water dam