This study retrospectively reviewed data from over 68,000 surgical procedures from 2010-2015 at a large academic medical center to analyze patterns of preventing postoperative nausea and vomiting (PONV). The review found that about half of patients received at least one preventative medication, but only 14.9% of high-risk patients received multiple medications. The study aims to identify opportunities to improve preventative care for PONV, especially among high-risk patients.