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MGMT 545 :: Goodfriend
OHSU Research Cytogenetics Fee for Service Lab
MGMT 545 :: Goodfriend
OHSU Research Cytogenetics Fee for Service Lab
Opportunities to Leverage Knowledge
and Expand the Business Model
MGMT 545 :: Goodfriend
OHSU Research Cytogenetics Fee for Service Lab
Opportunities
Market: Is there an unfulfilled or unanswered need?
Challenges: What is the right business model?
Nimble: How to continuously respond to the market
Manage Strategies to address uncertainty
MGMT 545 :: Goodfriend
OHSU Research Cytogenetics Fee for Service Lab
Opportunities
Seeking: Identifying a viable business model
Testing: Experimenting and hypothesizing
Listening: Internalizing the needs of customers
Refining: Iteratively responding and modifying
MGMT 545 :: Goodfriend
OHSU Research Cytogenetics Fee for Service Lab
Opportunities
Current State: Fee for service lab is about ten years old
A range of services are currently offered
Marketing has been by word-of-mouth
Sense there is an unfulfilled need
Competition: University of Wisconsin WiCell lab
Relationships: OHSU researchers
Knight Diagnostic Lab
Potential: Cancer research institutions
Pharmaceutical trials
Cell repositories
MGMT 545 :: Goodfriend
OHSU Research Cytogenetics Fee for Service Lab
Key principles: Craft a business model canvas
Develop an untested hypothesis
Define the requirements and resources
Prototype a minimum viable product
Road test by “getting out of the building”
Evaluate and refine the prototype
Repeat or pivot
Agile Development
MGMT 545 :: Goodfriend
OHSU Research Cytogenetics Fee for Service Lab
Strategize
Analyze
ImplementRoad Test
Evaluate
Agile Development
Revisit/ Refine
Pivot
MGMT 545 :: Goodfriend
OHSU Research Cytogenetics Fee for Service Lab
Business Model Canvas
Efficiency Value
Key Partnerships
Researchers
Cancer institutes
Institutional owners of
transgenic cores
Pharmaceutical companies
Key Activities
Karyotype chromosome analysis:
mouse/ human/ dog
Cell line verification via
karyotyping
Designer FISH probes
Reading cell samples & paraffin
tissue
Transgenic core testing to
improve clone outcomes
Breakage test to determine
genome instability
Value Proposition
Data and outcomes prove the
efficacy of services
Cost/ benefit of transgenic core
cell line verification/ business
case in time and cost
Web list of past and present
customers
Customized cell line testing
Parental cell line testing for
institutions
Rapid transgenic mouse studies
(24 – 48 hours)
Relationships
Knight Labs: self-labeled FISH
probes
Dr. Pejovic: chromosome
breakage studies
Dr. Drucker: confirmation FISH
Dr. Borzy: clinical trial support
Dr. Keller: karyotype
chromosome analysis
Customer Segments
Knight Labs
OHSU researchers
Dr. Chen, Harvard
Dr. McMann, USC
Pharmaceutical companies
clinical trials
Cell repositories: Coriell, ATCC
Key Resources
Confirmation of micro arrays
via custom FISH probes
Channels
How do we reach our
customers?
Cost Structure
$200/clone
8 to 10 samples per month
Are we charging enough??
Revenue Streams
Current price list is based on costs
Sliding scale based on funding source?
Can there be revenue sharing with the clinical lab?
Can custom FISH probes be licensed? Are they IP?
Competitors: WiCell University of Wisconsin
MGMT 545 :: Goodfriend
OHSU Research Cytogenetics Fee for Service Lab
Business Model Canvas
Efficiency Value
Key Partnerships
Researchers
Cancer institutes
Institutional owners of
transgenic cores
Pharmaceutical companies
Key Activities
Karyotype chromosome analysis:
mouse/ human/ dog
Cell line verification via
karyotyping
Designer FISH probes
Reading cell samples & paraffin
tissue
Transgenic core testing to
improve clone outcomes
Breakage test to determine
genome instability
Value Proposition
Data and outcomes prove the
efficacy of services
Cost/ benefit of transgenic core
cell line verification/ business
case in time and cost
Web list of past and present
customers
Customized cell line testing
Parental cell line testing for
institutions
Rapid transgenic mouse studies
(24 – 48 hours)
Relationships
Knight Labs: self-labeled FISH
probes
Dr. Pejovic: chromosome
breakage studies
Dr. Drucker: confirmation FISH
Dr. Borzy: clinical trial support
Dr. Keller: karyotype
chromosome analysis
Customer Segments
Knight Labs
OHSU researchers
Dr. Chen, Harvard
Dr. McMann, USC
Pharmaceutical companies
clinical trials
Cell repositories: Coriell, ATCC
Key Resources
Confirmation of micro arrays
via custom FISH probes
Channels
How do we reach our
customers?
Cost Structure
$200/clone
8 to 10 samples per month
Are we charging enough??
Revenue Streams
Current price list is based on costs
Sliding scale based on funding source?
Can there be revenue sharing with the clinical lab?
Can custom FISH probes be licensed? Are they IP?
Competitors: WiCell University of Wisconsin
Resource Driven
Innovations originating from existing infrastructure to expand or transform the business model
MGMT 545 :: Goodfriend
OHSU Research Cytogenetics Fee for Service Lab
Strategy
First Iteration Cycle – Six Month Plan
Develop a Hypothesis Analyze Implement Road Test Evaluate
“We can sell
transgenic core
testing to academic
research institutions.”
Define technical
specifications and
requirements
Identify key resources
and partnerships ISH
probes
Build prototype
(First round may be
virtual prototype)
Road test MVP with
select customer
segments
Document feedback,
efficacy, cost and
revenue
ç Revisit and Refine or Pivot to New Hypothesis ç	
  
Recommendation
Leverage agile development tools to create a fee-for-service lab start-up
Begin with a focus on transgenic core testing
Manage the staff time and resource investment
Embrace a nimble mindset and be ready to pivot
MGMT 545 :: Goodfriend
OHSU Research Cytogenetics Fee for Service Lab
Strategy
First Iteration Cycle – Six Month Plan
Develop a Hypothesis Analyze Implement Road Test Evaluate
“We can sell
transgenic core
testing to academic
research institutions.”
Define technical
specifications and
requirements
Identify key resources
and partnerships ISH
probes
Build prototype
(First round may be
virtual prototype)
Road test MVP with
select customer
segments
Document feedback,
efficacy, cost and
revenue
ç Revisit and Refine or Pivot to New Hypothesis ç	
  
Develop a Hypothesis
Frame the project objectives
Appropriate people/ right knowledge
Provide the appropriate resources
MGMT 545 :: Goodfriend
OHSU Research Cytogenetics Fee for Service Lab
Strategy
First Iteration Cycle – Six Month Plan
Develop a Hypothesis Analyze Implement Road Test Evaluate
“We can sell
transgenic core
testing to academic
research institutions.”
Define technical
specifications and
requirements
Identify key resources
and partnerships ISH
probes
Build prototype
(First round may be
virtual prototype)
Road test MVP with
select customer
segments
Document feedback,
efficacy, cost and
revenue
ç Revisit and Refine or Pivot to New Hypothesis ç	
  
Analyze
Co-create with others across the organization
Look beyond the status quo
Explore multiple possibilities
MGMT 545 :: Goodfriend
OHSU Research Cytogenetics Fee for Service Lab
Strategy
First Iteration Cycle – Six Month Plan
Develop a Hypothesis Analyze Implement Road Test Evaluate
“We can sell
transgenic core
testing to academic
research institutions.”
Define technical
specifications and
requirements
Identify key resources
and partnerships ISH
probes
Build prototype
(First round may be
virtual prototype)
Road test MVP with
select customer
segments
Document feedback,
efficacy, cost and
revenue
ç Revisit and Refine or Pivot to New Hypothesis ç	
  
Implement
Proof of concept via data and testimony
Demonstrate technique and speed
Create a tangible Minimum Viable Product (MVP)
MGMT 545 :: Goodfriend
OHSU Research Cytogenetics Fee for Service Lab
Strategy
First Iteration Cycle – Six Month Plan
Develop a Hypothesis Analyze Implement Road Test Evaluate
“We can sell
transgenic core
testing to academic
research institutions.”
Define technical
specifications and
requirements
Identify key resources
and partnerships ISH
probes
Build prototype
(First round may be
virtual prototype)
Road test MVP with
select customer
segments
Document feedback,
efficacy, cost and
revenue
ç Revisit and Refine or Pivot to New Hypothesis ç	
  
Road Test
Target a range of customers
Spend sufficient time with each one
Strong communication tools
MGMT 545 :: Goodfriend
OHSU Research Cytogenetics Fee for Service Lab
Strategy
First Iteration Cycle – Six Month Plan
Develop a Hypothesis Analyze Implement Road Test Evaluate
“We can sell
transgenic core
testing to academic
research institutions.”
Define technical
specifications and
requirements
Identify key resources
and partnerships ISH
probes
Build prototype
(First round may be
virtual prototype)
Road test MVP with
select customer
segments
Document feedback,
efficacy, cost and
revenue
ç Revisit and Refine or Pivot to New Hypothesis ç	
  
Evaluate
Continually re-assess
Re-visit the hypothesis
Manage synergies
MGMT 545 :: Goodfriend
OHSU Research Cytogenetics Fee for Service Lab
Strategy
First Iteration Cycle – Six Month Plan
Develop a Hypothesis Analyze Implement Road Test Evaluate
“We can sell
transgenic core
testing to academic
research institutions.”
Define technical
specifications and
requirements
Identify key resources
and partnerships ISH
probes
Build prototype
(First round may be
virtual prototype)
Road test MVP with
select customer
segments
Document feedback,
efficacy, cost and
revenue
ç Revisit and Refine or Pivot to New Hypothesis ç	
  
Six Month Outcomes
Validate there is a market for transgenic core testing or pivot to a new hypothesis
Sample customers regarding their interest and price expectations
Understand the resources needed to build a start-up
Map a path toward a proven business model
MGMT 545 :: Goodfriend
OHSU Research Cytogenetics Fee for Service Lab
Execution
Timeline: Start with a six month plan
Deploy an agile development technique
Track milestones and manage progress
Resources: Committed start-up team
Prototype development lab time
MVP value proposition
Travel and marketing budgets
Needs include: Strong customer relationships
A robust marketing strategy
Diversified revenue streams
A clearly defined cost structure
MGMT 545 :: Goodfriend
OHSU Research Cytogenetics Fee for Service Lab
Opportunities to Leverage Knowledge
and Expand the Business Model
MGMT 545 :: Goodfriend
OHSU Research Cytogenetics Fee for Service Lab
The following materials were referenced for this
presentation:
:: “Business Model Generation” Osterwalder & Pigneur, 2010
:: “Why the Lean Start-up Changes Everything” Blank, HBR, 2013
:: www.businessmodelhub.com
:: www.wicell.org
References

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Research Cytogenetic Lab Presentation

  • 1. MGMT 545 :: Goodfriend OHSU Research Cytogenetics Fee for Service Lab
  • 2. MGMT 545 :: Goodfriend OHSU Research Cytogenetics Fee for Service Lab Opportunities to Leverage Knowledge and Expand the Business Model
  • 3. MGMT 545 :: Goodfriend OHSU Research Cytogenetics Fee for Service Lab Opportunities Market: Is there an unfulfilled or unanswered need? Challenges: What is the right business model? Nimble: How to continuously respond to the market Manage Strategies to address uncertainty
  • 4. MGMT 545 :: Goodfriend OHSU Research Cytogenetics Fee for Service Lab Opportunities Seeking: Identifying a viable business model Testing: Experimenting and hypothesizing Listening: Internalizing the needs of customers Refining: Iteratively responding and modifying
  • 5. MGMT 545 :: Goodfriend OHSU Research Cytogenetics Fee for Service Lab Opportunities Current State: Fee for service lab is about ten years old A range of services are currently offered Marketing has been by word-of-mouth Sense there is an unfulfilled need Competition: University of Wisconsin WiCell lab Relationships: OHSU researchers Knight Diagnostic Lab Potential: Cancer research institutions Pharmaceutical trials Cell repositories
  • 6. MGMT 545 :: Goodfriend OHSU Research Cytogenetics Fee for Service Lab Key principles: Craft a business model canvas Develop an untested hypothesis Define the requirements and resources Prototype a minimum viable product Road test by “getting out of the building” Evaluate and refine the prototype Repeat or pivot Agile Development
  • 7. MGMT 545 :: Goodfriend OHSU Research Cytogenetics Fee for Service Lab Strategize Analyze ImplementRoad Test Evaluate Agile Development Revisit/ Refine Pivot
  • 8. MGMT 545 :: Goodfriend OHSU Research Cytogenetics Fee for Service Lab Business Model Canvas Efficiency Value Key Partnerships Researchers Cancer institutes Institutional owners of transgenic cores Pharmaceutical companies Key Activities Karyotype chromosome analysis: mouse/ human/ dog Cell line verification via karyotyping Designer FISH probes Reading cell samples & paraffin tissue Transgenic core testing to improve clone outcomes Breakage test to determine genome instability Value Proposition Data and outcomes prove the efficacy of services Cost/ benefit of transgenic core cell line verification/ business case in time and cost Web list of past and present customers Customized cell line testing Parental cell line testing for institutions Rapid transgenic mouse studies (24 – 48 hours) Relationships Knight Labs: self-labeled FISH probes Dr. Pejovic: chromosome breakage studies Dr. Drucker: confirmation FISH Dr. Borzy: clinical trial support Dr. Keller: karyotype chromosome analysis Customer Segments Knight Labs OHSU researchers Dr. Chen, Harvard Dr. McMann, USC Pharmaceutical companies clinical trials Cell repositories: Coriell, ATCC Key Resources Confirmation of micro arrays via custom FISH probes Channels How do we reach our customers? Cost Structure $200/clone 8 to 10 samples per month Are we charging enough?? Revenue Streams Current price list is based on costs Sliding scale based on funding source? Can there be revenue sharing with the clinical lab? Can custom FISH probes be licensed? Are they IP? Competitors: WiCell University of Wisconsin
  • 9. MGMT 545 :: Goodfriend OHSU Research Cytogenetics Fee for Service Lab Business Model Canvas Efficiency Value Key Partnerships Researchers Cancer institutes Institutional owners of transgenic cores Pharmaceutical companies Key Activities Karyotype chromosome analysis: mouse/ human/ dog Cell line verification via karyotyping Designer FISH probes Reading cell samples & paraffin tissue Transgenic core testing to improve clone outcomes Breakage test to determine genome instability Value Proposition Data and outcomes prove the efficacy of services Cost/ benefit of transgenic core cell line verification/ business case in time and cost Web list of past and present customers Customized cell line testing Parental cell line testing for institutions Rapid transgenic mouse studies (24 – 48 hours) Relationships Knight Labs: self-labeled FISH probes Dr. Pejovic: chromosome breakage studies Dr. Drucker: confirmation FISH Dr. Borzy: clinical trial support Dr. Keller: karyotype chromosome analysis Customer Segments Knight Labs OHSU researchers Dr. Chen, Harvard Dr. McMann, USC Pharmaceutical companies clinical trials Cell repositories: Coriell, ATCC Key Resources Confirmation of micro arrays via custom FISH probes Channels How do we reach our customers? Cost Structure $200/clone 8 to 10 samples per month Are we charging enough?? Revenue Streams Current price list is based on costs Sliding scale based on funding source? Can there be revenue sharing with the clinical lab? Can custom FISH probes be licensed? Are they IP? Competitors: WiCell University of Wisconsin Resource Driven Innovations originating from existing infrastructure to expand or transform the business model
  • 10. MGMT 545 :: Goodfriend OHSU Research Cytogenetics Fee for Service Lab Strategy First Iteration Cycle – Six Month Plan Develop a Hypothesis Analyze Implement Road Test Evaluate “We can sell transgenic core testing to academic research institutions.” Define technical specifications and requirements Identify key resources and partnerships ISH probes Build prototype (First round may be virtual prototype) Road test MVP with select customer segments Document feedback, efficacy, cost and revenue ç Revisit and Refine or Pivot to New Hypothesis ç   Recommendation Leverage agile development tools to create a fee-for-service lab start-up Begin with a focus on transgenic core testing Manage the staff time and resource investment Embrace a nimble mindset and be ready to pivot
  • 11. MGMT 545 :: Goodfriend OHSU Research Cytogenetics Fee for Service Lab Strategy First Iteration Cycle – Six Month Plan Develop a Hypothesis Analyze Implement Road Test Evaluate “We can sell transgenic core testing to academic research institutions.” Define technical specifications and requirements Identify key resources and partnerships ISH probes Build prototype (First round may be virtual prototype) Road test MVP with select customer segments Document feedback, efficacy, cost and revenue ç Revisit and Refine or Pivot to New Hypothesis ç   Develop a Hypothesis Frame the project objectives Appropriate people/ right knowledge Provide the appropriate resources
  • 12. MGMT 545 :: Goodfriend OHSU Research Cytogenetics Fee for Service Lab Strategy First Iteration Cycle – Six Month Plan Develop a Hypothesis Analyze Implement Road Test Evaluate “We can sell transgenic core testing to academic research institutions.” Define technical specifications and requirements Identify key resources and partnerships ISH probes Build prototype (First round may be virtual prototype) Road test MVP with select customer segments Document feedback, efficacy, cost and revenue ç Revisit and Refine or Pivot to New Hypothesis ç   Analyze Co-create with others across the organization Look beyond the status quo Explore multiple possibilities
  • 13. MGMT 545 :: Goodfriend OHSU Research Cytogenetics Fee for Service Lab Strategy First Iteration Cycle – Six Month Plan Develop a Hypothesis Analyze Implement Road Test Evaluate “We can sell transgenic core testing to academic research institutions.” Define technical specifications and requirements Identify key resources and partnerships ISH probes Build prototype (First round may be virtual prototype) Road test MVP with select customer segments Document feedback, efficacy, cost and revenue ç Revisit and Refine or Pivot to New Hypothesis ç   Implement Proof of concept via data and testimony Demonstrate technique and speed Create a tangible Minimum Viable Product (MVP)
  • 14. MGMT 545 :: Goodfriend OHSU Research Cytogenetics Fee for Service Lab Strategy First Iteration Cycle – Six Month Plan Develop a Hypothesis Analyze Implement Road Test Evaluate “We can sell transgenic core testing to academic research institutions.” Define technical specifications and requirements Identify key resources and partnerships ISH probes Build prototype (First round may be virtual prototype) Road test MVP with select customer segments Document feedback, efficacy, cost and revenue ç Revisit and Refine or Pivot to New Hypothesis ç   Road Test Target a range of customers Spend sufficient time with each one Strong communication tools
  • 15. MGMT 545 :: Goodfriend OHSU Research Cytogenetics Fee for Service Lab Strategy First Iteration Cycle – Six Month Plan Develop a Hypothesis Analyze Implement Road Test Evaluate “We can sell transgenic core testing to academic research institutions.” Define technical specifications and requirements Identify key resources and partnerships ISH probes Build prototype (First round may be virtual prototype) Road test MVP with select customer segments Document feedback, efficacy, cost and revenue ç Revisit and Refine or Pivot to New Hypothesis ç   Evaluate Continually re-assess Re-visit the hypothesis Manage synergies
  • 16. MGMT 545 :: Goodfriend OHSU Research Cytogenetics Fee for Service Lab Strategy First Iteration Cycle – Six Month Plan Develop a Hypothesis Analyze Implement Road Test Evaluate “We can sell transgenic core testing to academic research institutions.” Define technical specifications and requirements Identify key resources and partnerships ISH probes Build prototype (First round may be virtual prototype) Road test MVP with select customer segments Document feedback, efficacy, cost and revenue ç Revisit and Refine or Pivot to New Hypothesis ç   Six Month Outcomes Validate there is a market for transgenic core testing or pivot to a new hypothesis Sample customers regarding their interest and price expectations Understand the resources needed to build a start-up Map a path toward a proven business model
  • 17. MGMT 545 :: Goodfriend OHSU Research Cytogenetics Fee for Service Lab Execution Timeline: Start with a six month plan Deploy an agile development technique Track milestones and manage progress Resources: Committed start-up team Prototype development lab time MVP value proposition Travel and marketing budgets Needs include: Strong customer relationships A robust marketing strategy Diversified revenue streams A clearly defined cost structure
  • 18. MGMT 545 :: Goodfriend OHSU Research Cytogenetics Fee for Service Lab Opportunities to Leverage Knowledge and Expand the Business Model
  • 19. MGMT 545 :: Goodfriend OHSU Research Cytogenetics Fee for Service Lab The following materials were referenced for this presentation: :: “Business Model Generation” Osterwalder & Pigneur, 2010 :: “Why the Lean Start-up Changes Everything” Blank, HBR, 2013 :: www.businessmodelhub.com :: www.wicell.org References