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Acute & Chronic Renal injury Pathology
1. DR. Abhinav Golla.
MBBS.MD Pathology
Lab director Aadhya Medicure
Pathlabs
Assistant Professor (AIMS)
Lab Admin.
2. • What are the 3 barriers
involved in glomerular
filtration?
• The glomerular filtration
assembly is composed of
three main cellular barriers
that are critical for the
ultrafiltration process, the
• Fenestrated
endothelium,
• Glomerular basement
membrane.
• Highly specialized
podocytes.
3.
4.
5.
6.
7.
8. •What role do
podocytes have
in fluid filtration?
• Podocytes are highly
specialized cells, which form
multiple interdigitating foot
processes.
• Podocytes contribute to the
specific size and charge
characteristics of the
glomerular filtration
barrier, and their damage leads to
a retraction of their foot processes
and proteinuria
