The document reports on prostate cancer incidence and cases in Ireland from 2004-2007 based on data from various hospitals. It discusses establishing a Prostate Cancer Institute (PCI) through a partnership between NUIG and GUH. The goals of the PCI are to develop new prostate cancer drugs, enhance treatment delivery and education programs, and create jobs in biopharma and medical devices. It outlines the governance structure and goals of establishing the PCI by convening advisory panels and beginning fundraising efforts from 2009-2015.

1. Prostate Cancer Institute Report to NUIG Foundation 15 th December 2010

2. Prostate cancer incidence 2004-2006 by County

3. New and suspected prostate cancer cases seen by hospital Ireland 2006 - 2007 1.4:1 150 Unknown 107 105 Waterford 3:1 1100 820 365 272 UCHG 2:1 335 Unknown 180 Unknown St Vincent’s 2.6:1 280 Unknown 105 101 St James’ 1.6:1 274 304 171 145 MUH 5:1 (est) 1200(est) 1000 (estimate) 240 220 Mater 3:1 311 301 104 112 Limerick Regional 2:1 382 340 210 186 CUH 2.5:1 453 530 179 151 Beaumont 2.5:1 676 797 273 327 AMNCH Benign: malignant ratio 2007 Suspected prostate cancer cases seen in 2007 Suspected prostate cancer cases seen in 2006 New prostate cancer cases diagnosed in 2007 New prostate cancer cases diagnosed in 2006 Hospital

4. Critical Mass of Key Components Significant basic science ongoing NUIG/ PRTLI Translational Research Facilities Clinical Research Facilities Clinical Resources Patients Galway University and GUH NUIG Foundation Prostate Cancer Institute Strategic partners

5. Strategic research partners CRF/TRF REMEDI PCI NCBRI

6. Institute governance model Prostate Cancer Institute Medical Advisory Panel Strategic Advisory Panel Scientific Advisory Panel Constituent NUIG

7. Three pillars of activity Develop new drugs for prostate cancer Enhance the treatment delivery Create employment Biopharma Medical devises Cancer institute care facility Reinvestment in healthcare

8. Key soundings & support Patron President of Ireland Mary McAleese Jim Browne President NUIG John McNamara University Foundation Chair Tom Joyce CEO University Foundation Bernard Collins Chairman VHi Pat Fottrell Chairman SFI Frank Gannon President SFI Terry Smith Senior VP Research NUIG Ruth Curtis Professor Psychology NUIG Frank Giles professor Hem-Onc San Antonio Tim O’Brien Professor Medicine NUIG, Chair REMEDI Michael Kerin Professor Surgery NUIG Chair NCBRI Eamonn Rogers Head GU Surgery GUH Larry Egan Professor Pharmacology NUIG John Burke, Padraic O’Ceidigh, Michael Somers, Jim Sweeney

9. Patron President Mary McAleese Agreement on file 29 th April 2009 Oficial opening Ceremony 1 st April 2011

10. Goals 2009 Convene Trustees Trustee meeting schedule (2009-2010) Fundraising strategy (CCW, University, ?SFI, Others) Launch Convene key advisory panels Scientific Medical Strategic

11. Goals 2010-2015 Develop Prostate Science Team New drugs Enhance Education Programs Enhance Clinical Programs

12. PCI Structure Frank Sullivan Director Advisory Council Bernard Collins Jim Sweeney Ruth Curtis Padraic O’Ceidigh

13. Scientific Council Frank Giles (Chair) Tim O’Brien Michael Kerin Frank Gannon Gerry O’Sullivan Ian Thompson Anthony d’Amico Steve Hahn Frank Sullivan

14. Medical Council Eamonn Rogers Maccon Keane Paul Donnellan Michael Corcoran Killian Walsh Frank Sullivan