Problems solved by OptiFer® products
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Problems on different levels solved by OptiFer® products Importer/Distributor level Retail level End user level Medical OptiFer® tablets are based on natural bovine heme iron and will safely and efficiently keep iron counts at an optimal level
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Newer Iron therapy for Anemia in pregnancy
Role of heme iron polypeptide for treating and preventing anemia
Chelating agent - drdhriti
A Power point presentation on "Chelating agents" suitable for UG MBBS level Medical students
White paper "Iron Therapy without problems"
This white paper will discuss iron therapy in general, why it is sometimes problematic,mainly due to tolerance and practical issues for those suffering from iron deficiency.
Important groups that are discussed in this aspect are children, young girls, fertile females, seniors and people with chronic diseases such as IBD, CHF, CKD that affect the iron metabolism and how Heme‐Iron supplementation change this situation.
The target is to inform the medicinal and pharmaceutical communities of this relatively new form of therapy and why it has great benefits compared to the traditional methods.
Novos produtos da série OptiFer®
A deficiência de ferro é o problema de saúde relacionado à dieta mais comum no mundo e os efeitos sobre a saúde humana se manifestam num largo espectro. A importância do ferro heme na dieta não pode ser subestimada. "A deficiência de ferro se manifesta como anemia em até 2 bilhões de pessoas, prejudica o desenvolvimento físico e mental em crianças e pode exacerbar muitos outros problemas de saúde.", segundo relato da Joint World Health Organization Centers for Disease Control, organização voltada ao controle de doenças.
OptiFer® vantagens em nível internacional
- A Série OptiFer® de Ferro-Heme Natural não tem efeitos colaterais reportados. Em todos os estudos clínicos realizados até agora o ferro-heme se mostra perfeito no quesito tolerância
- A Série OptiFer® apresenta a formulação mais eficiente disponível: o ferro-heme é várias vezes mais absorvido do que o seu equivalente em ferro sintético. A proporção é de 20-40% para ferro-heme em diferentes estudos em comparação com 1-4% ou menos de ferro sintético, que geralmente tem uma absorção inferior a 1%.
B vitaminas e ferro
A suplementação com ácido fólico, com e sem outras vitaminas B, reduzem os níveis de homocisteína no sangue (um fator de risco cardiovascular).
OptiFer® B é um novo comprimido que contém o extremamente bem tolerado e eficiente ferro heme. Ele também contém vitaminas B 6, B 12 e ácido fólico.
OptiFer® B é projetado especialmente para ajudar a formação do
sangue quando necessário em situações diferentes.
B vitamins and iron
The body needs access to vitamin B12 to produce red blood cells. A lack of this vitamin can lead to anaemia.Folic acid deficiency can cause anemia. Anemia is a condition where you have too few RBCs. Anemia can deprive your tissues of oxygen it needs, because red blood cells carry the oxygen. Symptoms of a deficiency depends on what type of vitamin B you lack. They can range from fatigue and confusion, to anemia or a compromised immune system. Skin rashes also can occur.
Recommended
Newer Iron therapy for Anemia in pregnancy
Role of heme iron polypeptide for treating and preventing anemia
Chelating agent - drdhriti
A Power point presentation on "Chelating agents" suitable for UG MBBS level Medical students
White paper "Iron Therapy without problems"
This white paper will discuss iron therapy in general, why it is sometimes problematic,mainly due to tolerance and practical issues for those suffering from iron deficiency.
Important groups that are discussed in this aspect are children, young girls, fertile females, seniors and people with chronic diseases such as IBD, CHF, CKD that affect the iron metabolism and how Heme‐Iron supplementation change this situation.
The target is to inform the medicinal and pharmaceutical communities of this relatively new form of therapy and why it has great benefits compared to the traditional methods.
Novos produtos da série OptiFer®
A deficiência de ferro é o problema de saúde relacionado à dieta mais comum no mundo e os efeitos sobre a saúde humana se manifestam num largo espectro. A importância do ferro heme na dieta não pode ser subestimada. "A deficiência de ferro se manifesta como anemia em até 2 bilhões de pessoas, prejudica o desenvolvimento físico e mental em crianças e pode exacerbar muitos outros problemas de saúde.", segundo relato da Joint World Health Organization Centers for Disease Control, organização voltada ao controle de doenças.
OptiFer® vantagens em nível internacional
- A Série OptiFer® de Ferro-Heme Natural não tem efeitos colaterais reportados. Em todos os estudos clínicos realizados até agora o ferro-heme se mostra perfeito no quesito tolerância
- A Série OptiFer® apresenta a formulação mais eficiente disponível: o ferro-heme é várias vezes mais absorvido do que o seu equivalente em ferro sintético. A proporção é de 20-40% para ferro-heme em diferentes estudos em comparação com 1-4% ou menos de ferro sintético, que geralmente tem uma absorção inferior a 1%.
B vitaminas e ferro
A suplementação com ácido fólico, com e sem outras vitaminas B, reduzem os níveis de homocisteína no sangue (um fator de risco cardiovascular).
OptiFer® B é um novo comprimido que contém o extremamente bem tolerado e eficiente ferro heme. Ele também contém vitaminas B 6, B 12 e ácido fólico.
OptiFer® B é projetado especialmente para ajudar a formação do
sangue quando necessário em situações diferentes.
B vitamins and iron
The body needs access to vitamin B12 to produce red blood cells. A lack of this vitamin can lead to anaemia.Folic acid deficiency can cause anemia. Anemia is a condition where you have too few RBCs. Anemia can deprive your tissues of oxygen it needs, because red blood cells carry the oxygen. Symptoms of a deficiency depends on what type of vitamin B you lack. They can range from fatigue and confusion, to anemia or a compromised immune system. Skin rashes also can occur.
OptiFer® solves problems
The OptiFer® series of heme iron supplements solve many problems inherent to iron therapy. MediTec FerroCare Division offers information on www.optifer.international and www.hemeiron.com as well as for instance the eBook “Heme Iron”. All OptiFer® products contain original heme iron.
OptiFer® é econômico porque ..
Com uma dosagem de um ou dois comprimidos, uma vez por dia, a terapia com ferro heme é econômica em comparação com as alternativas.
A dosagem permanecerá a mesma até mesmo no caso de terapias mais longas.
OptiFer@ is economical
With a dosage of one or two tablets once
per day heme iron therapy is economical compared to the alternatives. Dosage will stay the same even over
longer therapy. There are considerably less potentially
therapy-ruining side-effects.
For MediTec it is more important to help as many iron deficiency sufferers worldwide as possible than optimising product calculus.
We are looking to reach large markets, not least in the third world.
O que a organização mundial de saúde oms tem a dizer sobre a deficiência ...
A deficiência de ferro é o distúrbio nutricional mais comum e difundido no mundo. Os produtos OptiFer® têm vantagens e um enorme potencial internacional. São seguros. Não há casos relatados de efeitos colaterais graves ou envenenamentos após longo tempo de uso maciço de ferro heme na Escandinávia.
What the world health organisation WHO has to say on iron deficiency
Iron deficiency is a big problem internationally. The OptiFer® series of heme iron supplements has the potential for change worldwide
Problemas com a suplementação de ferro, porque e o que fazer
Não é fácil encontrar o suplemento certo. Há uma infinidade de medicamentos e suplementos no mercado, e cada um alega resolver todos os problemas da melhor maneira. Será que vou tolerar a suplementação? É eficiente? É conveniente para mim? É seguro?
Problems with iron supplementation? Why and what to do.
Problems with iron supplementation?
What to do.
It is not easy to find the right one.
There is a multitude of medications and supplements out there and each claims to solve all problems in the best way.
Will I tolerate the supplementation?
Is it efficient?
Is it convenient for me?
Is it safe?
Estado nutricional e peso ao nascer
Estudos e pesquisas epidemiológicas realizados pelo professor inglês David Barkers mostram que o estado nutricional da mãe, principalmente com relação à contagem de hemoglobina, tem consequências importantes no desenvolvimento fetal.
Nutritional status and birth weight
Please take a look..
Michael Collan 8:09 PM
To: Leila País de Miranda
Nutritional status and birth weight
English Professor David Barkers epidemological research studies show that the nutritional status of the mother, mainly as hemoglobin count has an effect on fetal development.
Doença cardíaca crônica e Anemia
A insuficiência cardíaca é uma doença muito comum, com morbidade e mortalidade severa, e é um motivo freqüente de internação.
A anemia e uma insuficiência renal concomitante são dois principais fatores de risco que contribuem para a gravidade do caso
CKD and anaemia
Chronic kidney disease (CKD) is a gradual and usually permanent loss of kidney function over time. This happens gradually over time, usually months to years. Anemia develops when the kidneys fail to produce enough erythropoietin, EPO, the hormone that directs the bones to make red blood cells.
Ckd and anaemia p
A doença renal crônica (DRC) é uma perda gradual e geralmente permanente da função renal ao longo do tempo. A anemia se desenvolve quando os rins não conseguem produzir suficiente eritropoietina, EPO, o hormônio que comanda a produção de glóbulos vermelhos pelos ossos.
CHD and anaemia
Chronic heart disease and Anaemia. Heart failure is a very common disease, with severe morbidity and mortality, and is a frequent reason of hospitalization.
Anemia and a concurrent renal impairment are two major risk factors contributing to the severity of the outcome.
Heme iron is absorbed through a separate pathway and does not have to be discontinued when intravenous treatment is started. This can allow for longer intervals between resource-heavy, inconvenient and painful injections. Oxidative stress is also avoided.
Heme iron does not need to be discontinued during injection or EPO therapy like non-heme oral iron.
Boas fontes de ferro
A ingestão diária deve ser de pelo menos 18 mg de ferro para compensar a menstruação e outras perdas.
Um comprimido OptiFer® contém 18 mg de ferro.
Não há risco de sobredosagem com ferro heme.
Good sources for iron
Required daily dose is minimum 18 mg. Everybody´s heard about paisley and liver on so on. They are good. But you need quite a bit.
O futuro dos suplementos de ferro
O ferro heme é o mesmo tipo que é encontrado em aves, peixes e carnes.
É natural para o corpo, a molécula de hemoglobina é absorvida eficientemente como uma unidade inteira, sem ter que ser partida.
Portanto, não há nenhuma chance da terapia ser arruinada por efeitos colaterais.
The future of iron supplementation
Too many people know from personal experience that iron supplementation is not always problem free..
But there is something that works.
Proposições únicas de venda de ferro heme.
O ferro heme bovino natural em OptiFer® é absorvido de forma cinco vezes mais eficiente do que o ferro não heme e tem excelente tolerabilidade.
Quanto de opti fer® é necessário
Quanto de OptiFer® é necessário quando a contagem de hemoglobina é baixa? A concentração de hemoglobina
não deve ser inferior a 12 g/dl
Os suplementos OptiFer® de ferro heme/não-heme são eficientes e muito bem tolerados
How much optifer is needed
How much OptiFer® is needed when the Hemoglobin
count is low? Hemoglobin concentration
should not go below 12 g/dl
BENIGN PROSTATIC HYPERPLASIA.BPH. BPHpdf
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
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This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
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OptiFer® solves problems
The OptiFer® series of heme iron supplements solve many problems inherent to iron therapy. MediTec FerroCare Division offers information on www.optifer.international and www.hemeiron.com as well as for instance the eBook “Heme Iron”. All OptiFer® products contain original heme iron.
OptiFer® é econômico porque ..
Com uma dosagem de um ou dois comprimidos, uma vez por dia, a terapia com ferro heme é econômica em comparação com as alternativas.
A dosagem permanecerá a mesma até mesmo no caso de terapias mais longas.
OptiFer@ is economical
With a dosage of one or two tablets once
per day heme iron therapy is economical compared to the alternatives. Dosage will stay the same even over
longer therapy. There are considerably less potentially
therapy-ruining side-effects.
For MediTec it is more important to help as many iron deficiency sufferers worldwide as possible than optimising product calculus.
We are looking to reach large markets, not least in the third world.
O que a organização mundial de saúde oms tem a dizer sobre a deficiência ...
A deficiência de ferro é o distúrbio nutricional mais comum e difundido no mundo. Os produtos OptiFer® têm vantagens e um enorme potencial internacional. São seguros. Não há casos relatados de efeitos colaterais graves ou envenenamentos após longo tempo de uso maciço de ferro heme na Escandinávia.
What the world health organisation WHO has to say on iron deficiency
Iron deficiency is a big problem internationally. The OptiFer® series of heme iron supplements has the potential for change worldwide
Problemas com a suplementação de ferro, porque e o que fazer
Não é fácil encontrar o suplemento certo. Há uma infinidade de medicamentos e suplementos no mercado, e cada um alega resolver todos os problemas da melhor maneira. Será que vou tolerar a suplementação? É eficiente? É conveniente para mim? É seguro?
Problems with iron supplementation? Why and what to do.
Problems with iron supplementation?
What to do.
It is not easy to find the right one.
There is a multitude of medications and supplements out there and each claims to solve all problems in the best way.
Will I tolerate the supplementation?
Is it efficient?
Is it convenient for me?
Is it safe?
Estado nutricional e peso ao nascer
Estudos e pesquisas epidemiológicas realizados pelo professor inglês David Barkers mostram que o estado nutricional da mãe, principalmente com relação à contagem de hemoglobina, tem consequências importantes no desenvolvimento fetal.
Nutritional status and birth weight
Please take a look..
Michael Collan 8:09 PM
To: Leila País de Miranda
Nutritional status and birth weight
English Professor David Barkers epidemological research studies show that the nutritional status of the mother, mainly as hemoglobin count has an effect on fetal development.
Doença cardíaca crônica e Anemia
A insuficiência cardíaca é uma doença muito comum, com morbidade e mortalidade severa, e é um motivo freqüente de internação.
A anemia e uma insuficiência renal concomitante são dois principais fatores de risco que contribuem para a gravidade do caso
CKD and anaemia
Chronic kidney disease (CKD) is a gradual and usually permanent loss of kidney function over time. This happens gradually over time, usually months to years. Anemia develops when the kidneys fail to produce enough erythropoietin, EPO, the hormone that directs the bones to make red blood cells.
Ckd and anaemia p
A doença renal crônica (DRC) é uma perda gradual e geralmente permanente da função renal ao longo do tempo. A anemia se desenvolve quando os rins não conseguem produzir suficiente eritropoietina, EPO, o hormônio que comanda a produção de glóbulos vermelhos pelos ossos.
CHD and anaemia
Chronic heart disease and Anaemia. Heart failure is a very common disease, with severe morbidity and mortality, and is a frequent reason of hospitalization.
Anemia and a concurrent renal impairment are two major risk factors contributing to the severity of the outcome.
Heme iron is absorbed through a separate pathway and does not have to be discontinued when intravenous treatment is started. This can allow for longer intervals between resource-heavy, inconvenient and painful injections. Oxidative stress is also avoided.
Heme iron does not need to be discontinued during injection or EPO therapy like non-heme oral iron.
Boas fontes de ferro
A ingestão diária deve ser de pelo menos 18 mg de ferro para compensar a menstruação e outras perdas.
Um comprimido OptiFer® contém 18 mg de ferro.
Não há risco de sobredosagem com ferro heme.
Good sources for iron
Required daily dose is minimum 18 mg. Everybody´s heard about paisley and liver on so on. They are good. But you need quite a bit.
O futuro dos suplementos de ferro
O ferro heme é o mesmo tipo que é encontrado em aves, peixes e carnes.
É natural para o corpo, a molécula de hemoglobina é absorvida eficientemente como uma unidade inteira, sem ter que ser partida.
Portanto, não há nenhuma chance da terapia ser arruinada por efeitos colaterais.
The future of iron supplementation
Too many people know from personal experience that iron supplementation is not always problem free..
But there is something that works.
Proposições únicas de venda de ferro heme.
O ferro heme bovino natural em OptiFer® é absorvido de forma cinco vezes mais eficiente do que o ferro não heme e tem excelente tolerabilidade.
Quanto de opti fer® é necessário
Quanto de OptiFer® é necessário quando a contagem de hemoglobina é baixa? A concentração de hemoglobina
não deve ser inferior a 12 g/dl
Os suplementos OptiFer® de ferro heme/não-heme são eficientes e muito bem tolerados
How much optifer is needed
How much OptiFer® is needed when the Hemoglobin
count is low? Hemoglobin concentration
should not go below 12 g/dl
More from Michael Collan (20)
O que a organização mundial de saúde oms tem a dizer sobre a deficiência ...
O que a organização mundial de saúde oms tem a dizer sobre a deficiência ...
What the world health organisation WHO has to say on iron deficiency
What the world health organisation WHO has to say on iron deficiency
Problemas com a suplementação de ferro, porque e o que fazer
Problemas com a suplementação de ferro, porque e o que fazer
Problems with iron supplementation? Why and what to do.
Problems with iron supplementation? Why and what to do.
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BENIGN PROSTATIC HYPERPLASIA.BPH. BPHpdf
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
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Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journey
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Alcohol_Dr. Jeenal Mistry MD Pharmacology.pdf
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Flu Vaccine Alert in Bangalore Karnataka
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
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The Normal Electrocardiogram - Part I of II
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
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