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Cochrane Infectious Diseases Group
www.liv.ac.uk/evidence




            PRIORITISING WITHIN A COCHRANE
            REVIEW GROUP
            TWEAKING OUR CULTURE




              Paul Garner
              Cochrane Infectious Diseases Group


       © The Liverpool School of Tropical Medicine   1
LIVERPOOL




      European Capital of Culture




© The Liverpool School of Tropical Medicine   2
© The Liverpool School of Tropical Medicine   3
Lambanana




© The Liverpool School of Tropical Medicine   4
Lambanana




© The Liverpool School of Tropical Medicine   5
Lambanana




© The Liverpool School of Tropical Medicine   6
Lambanana




© The Liverpool School of Tropical Medicine   7
© The Liverpool School of Tropical Medicine   9
LIVERPOOL




      Team culture




© The Liverpool School of Tropical Medicine   10
Liverpool




 Five times
European Cup
 Champions
GOAL ORIENTATED CULTURE




      Cochrane Infectious Diseases Group needs GOALS




© The Liverpool School of Tropical Medicine            14
This talk



•     Why the Editorial Team developed a strategic plan

•     Aspects of implementation

•     Implications for the Cochrane Collaboration as a whole




© The Liverpool School of Tropical Medicine                    15
What was the need?
Post-review reflective audit



Author 1:                      district medical officer
Author 2:                      hospital doctor

AUTHORS and CIDG staff had spent months on this

CONCLUSION

•     The system had failed this people
•     Neither really had a chance of succeeding
•     Cochrane volunteerism was not working

•     Failing with our customers: the authors

© The Liverpool School of Tropical Medicine               16
Not responded to one of our main customers


      World Health Organization wanted head to head comparisons
      of artemisinin combination treatments for malaria

3. One very large review

5. 4 medium sized reviews

7. 14 small reviews (with overview)

      Stuck because we knew option 1 was needed, but 2-3 more
      compatible with volunteers




© The Liverpool School of Tropical Medicine                       17
PROBLEMS                                      RESPONSE
 • Delays with
   submission
                                              Editors meeting
 • Poor quality protocols                          2 days

 • Reviews we could not
   accept                                     Strategic plan

 • Massive work load for
   full time Editor


© The Liverpool School of Tropical Medicine                     18
Definition of impact review
(any of the following)


•     Likely to generate considerable interest in the international
      public health community;

•     has the potential to change policy or treatments with a
      substantive impact on the United Nations’ Millennium
      Development Goals

•     is frequently cited in the scientific literature;

•      is of considerable public interest and likely to capture high
      levels of press coverage.




© The Liverpool School of Tropical Medicine                            21
EACH REVIEW IS A RESEARCH
      PROJECT




      Needs managing like any other




© The Liverpool School of Tropical Medicine   22
WHAT ARE HIGH PRIORITY TOPIC?




      Strategically important or reviews requested
      by policymakers with a deadline
      With 2+ trials




© The Liverpool School of Tropical Medicine          23
4 STEPS


Try and elicit authors to do this

3.       Appraise title registration form and the team

5.       Build team

7.       Find support (salary, meetings, visits)

9.       Actively manage




© The Liverpool School of Tropical Medicine              24
STEP 1. APPRAISE Title registration




© The Liverpool School of Tropical Medicine   25
APPRAISE TEAM. Only accept if

•     Demonstrable topic expertise (published peer-reviewed articles
      in the topic)

•     Completed at least 1 Cochrane Review or equivalent

•     Contact author has time to dedicate to review (3 to 6 months
      for review with > 3 trials)




© The Liverpool School of Tropical Medicine                            26
Step 2. Build team
If team have potential but have gaps, indicate this to them

See if they can solve it

We do make suggestions




© The Liverpool School of Tropical Medicine                   27
CIDG authors from the Africa Cochrane Network




© The Liverpool School of Tropical Medicine     28
Step 3. Find support
•     Help find financial support e.g. Salary, author meeting

•     Build in deliverables to contract




© The Liverpool School of Tropical Medicine                     29
The Iron Team (IRON IN MALARIA)


•     Juliana, from Nigeria:                  Naive author, clinician

•     Joseph, MRC The Gambia:                 Full time researcher


EDITORIAL TEAM ADDED

•     Mical Paul                              Editor and researcher
                                              Extensive experience in SR

•     Dafna                                   Research assistant, clinical
                                              Employed for four months
GRANT TO JULIANA


© The Liverpool School of Tropical Medicine                                  30
© The Liverpool School of Tropical Medicine   31
Step 4. Actively Manage

•     Check on progress

•     Dialogue

•     Conference calls




© The Liverpool School of Tropical Medicine   32
2009+


•     Further develop response mode for reviews

•     Same as “high priority topics” except we need to assemble
      review team




© The Liverpool School of Tropical Medicine                       33
LOW PRIORITY TOPIC




      Results of the review unlikely to be relevant to achieving the
      MDGs




© The Liverpool School of Tropical Medicine                            34
Assess Team on title registration form
      Includes topic expertise by way of discipline or training

      Has capacity to do the review

      Consortium Partner or Cochrane Centre can provide technical
      support




      ….then accept

© The Liverpool School of Tropical Medicine                         35
Implications to the Effective Health Care Research
Programme Consortium


• In developed countries, massive investment in
  commissioned systematic reviews


• In developing countries, Cochrane, some basic
  courses, but expected to do reviews for free


• Vital to address this fundamental imbalance




© The Liverpool School of Tropical Medicine          36
NEW CADRE OF AUTHORS




      3 new authors from the UK:

      Self sufficient, know the methods, quietly complete updates




© The Liverpool School of Tropical Medicine                         37
CIDG authors




© The Liverpool School of Tropical Medicine   38
WHAT IS BRAND?




© The Liverpool School of Tropical Medicine   39
Definition of Brand


                Initial value                 Damien Hirst adds his
                                                    signature

                   £ 60,000                       £   1,600,000




© The Liverpool School of Tropical Medicine                           41
WHAT IS OUR BRAND?




      Quality, timeliness and independence


© The Liverpool School of Tropical Medicine   42
Cochrane reviews

      We know we have issues with quality

      Every single review effect the future of us all

      We need to change collectively before the
      funders demand accountability




© The Liverpool School of Tropical Medicine             43
Cochrane Collaboration needs to build the brand


• Fewer, larger, higher quality reviews

• Substantive editor input at title stage

• Teams that include experienced authors

• Fellowships for authors




© The Liverpool School of Tropical Medicine       44
COCHRANE COLLABORATION CAN
      CHANGE




      NOW IS THE TIME TO MAKE THIS HAPPEN




© The Liverpool School of Tropical Medicine   45
Acknowledgements


•     Thanks to Harriet MacLehose for co-managing the development
      of the strategic plan and being responsible for implementing it


•     And all the editors and staff in Liverpool




© The Liverpool School of Tropical Medicine                             46

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Prioritising within a Cochrane Review Group

  • 1. Cochrane Infectious Diseases Group www.liv.ac.uk/evidence PRIORITISING WITHIN A COCHRANE REVIEW GROUP TWEAKING OUR CULTURE Paul Garner Cochrane Infectious Diseases Group © The Liverpool School of Tropical Medicine 1
  • 2. LIVERPOOL European Capital of Culture © The Liverpool School of Tropical Medicine 2
  • 3. © The Liverpool School of Tropical Medicine 3
  • 4. Lambanana © The Liverpool School of Tropical Medicine 4
  • 5. Lambanana © The Liverpool School of Tropical Medicine 5
  • 6. Lambanana © The Liverpool School of Tropical Medicine 6
  • 7. Lambanana © The Liverpool School of Tropical Medicine 7
  • 8.
  • 9. © The Liverpool School of Tropical Medicine 9
  • 10. LIVERPOOL Team culture © The Liverpool School of Tropical Medicine 10
  • 11.
  • 13.
  • 14. GOAL ORIENTATED CULTURE Cochrane Infectious Diseases Group needs GOALS © The Liverpool School of Tropical Medicine 14
  • 15. This talk • Why the Editorial Team developed a strategic plan • Aspects of implementation • Implications for the Cochrane Collaboration as a whole © The Liverpool School of Tropical Medicine 15
  • 16. What was the need? Post-review reflective audit Author 1: district medical officer Author 2: hospital doctor AUTHORS and CIDG staff had spent months on this CONCLUSION • The system had failed this people • Neither really had a chance of succeeding • Cochrane volunteerism was not working • Failing with our customers: the authors © The Liverpool School of Tropical Medicine 16
  • 17. Not responded to one of our main customers World Health Organization wanted head to head comparisons of artemisinin combination treatments for malaria 3. One very large review 5. 4 medium sized reviews 7. 14 small reviews (with overview) Stuck because we knew option 1 was needed, but 2-3 more compatible with volunteers © The Liverpool School of Tropical Medicine 17
  • 18. PROBLEMS RESPONSE • Delays with submission Editors meeting • Poor quality protocols 2 days • Reviews we could not accept Strategic plan • Massive work load for full time Editor © The Liverpool School of Tropical Medicine 18
  • 19.
  • 20.
  • 21. Definition of impact review (any of the following) • Likely to generate considerable interest in the international public health community; • has the potential to change policy or treatments with a substantive impact on the United Nations’ Millennium Development Goals • is frequently cited in the scientific literature; • is of considerable public interest and likely to capture high levels of press coverage. © The Liverpool School of Tropical Medicine 21
  • 22. EACH REVIEW IS A RESEARCH PROJECT Needs managing like any other © The Liverpool School of Tropical Medicine 22
  • 23. WHAT ARE HIGH PRIORITY TOPIC? Strategically important or reviews requested by policymakers with a deadline With 2+ trials © The Liverpool School of Tropical Medicine 23
  • 24. 4 STEPS Try and elicit authors to do this 3. Appraise title registration form and the team 5. Build team 7. Find support (salary, meetings, visits) 9. Actively manage © The Liverpool School of Tropical Medicine 24
  • 25. STEP 1. APPRAISE Title registration © The Liverpool School of Tropical Medicine 25
  • 26. APPRAISE TEAM. Only accept if • Demonstrable topic expertise (published peer-reviewed articles in the topic) • Completed at least 1 Cochrane Review or equivalent • Contact author has time to dedicate to review (3 to 6 months for review with > 3 trials) © The Liverpool School of Tropical Medicine 26
  • 27. Step 2. Build team If team have potential but have gaps, indicate this to them See if they can solve it We do make suggestions © The Liverpool School of Tropical Medicine 27
  • 28. CIDG authors from the Africa Cochrane Network © The Liverpool School of Tropical Medicine 28
  • 29. Step 3. Find support • Help find financial support e.g. Salary, author meeting • Build in deliverables to contract © The Liverpool School of Tropical Medicine 29
  • 30. The Iron Team (IRON IN MALARIA) • Juliana, from Nigeria: Naive author, clinician • Joseph, MRC The Gambia: Full time researcher EDITORIAL TEAM ADDED • Mical Paul Editor and researcher Extensive experience in SR • Dafna Research assistant, clinical Employed for four months GRANT TO JULIANA © The Liverpool School of Tropical Medicine 30
  • 31. © The Liverpool School of Tropical Medicine 31
  • 32. Step 4. Actively Manage • Check on progress • Dialogue • Conference calls © The Liverpool School of Tropical Medicine 32
  • 33. 2009+ • Further develop response mode for reviews • Same as “high priority topics” except we need to assemble review team © The Liverpool School of Tropical Medicine 33
  • 34. LOW PRIORITY TOPIC Results of the review unlikely to be relevant to achieving the MDGs © The Liverpool School of Tropical Medicine 34
  • 35. Assess Team on title registration form Includes topic expertise by way of discipline or training Has capacity to do the review Consortium Partner or Cochrane Centre can provide technical support ….then accept © The Liverpool School of Tropical Medicine 35
  • 36. Implications to the Effective Health Care Research Programme Consortium • In developed countries, massive investment in commissioned systematic reviews • In developing countries, Cochrane, some basic courses, but expected to do reviews for free • Vital to address this fundamental imbalance © The Liverpool School of Tropical Medicine 36
  • 37. NEW CADRE OF AUTHORS 3 new authors from the UK: Self sufficient, know the methods, quietly complete updates © The Liverpool School of Tropical Medicine 37
  • 38. CIDG authors © The Liverpool School of Tropical Medicine 38
  • 39. WHAT IS BRAND? © The Liverpool School of Tropical Medicine 39
  • 40.
  • 41. Definition of Brand Initial value Damien Hirst adds his signature £ 60,000 £ 1,600,000 © The Liverpool School of Tropical Medicine 41
  • 42. WHAT IS OUR BRAND? Quality, timeliness and independence © The Liverpool School of Tropical Medicine 42
  • 43. Cochrane reviews We know we have issues with quality Every single review effect the future of us all We need to change collectively before the funders demand accountability © The Liverpool School of Tropical Medicine 43
  • 44. Cochrane Collaboration needs to build the brand • Fewer, larger, higher quality reviews • Substantive editor input at title stage • Teams that include experienced authors • Fellowships for authors © The Liverpool School of Tropical Medicine 44
  • 45. COCHRANE COLLABORATION CAN CHANGE NOW IS THE TIME TO MAKE THIS HAPPEN © The Liverpool School of Tropical Medicine 45
  • 46. Acknowledgements • Thanks to Harriet MacLehose for co-managing the development of the strategic plan and being responsible for implementing it • And all the editors and staff in Liverpool © The Liverpool School of Tropical Medicine 46