Prescribing in bacterial skin infections

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This document discusses prescribing treatments for various bacterial skin infections, including using topical antiseptic solutions or antibiotics for impetigo, antiseptic soaps and topical or systemic antibiotics for bacterial folliculitis, and treatments ranging from topical antibiotics to incision and drainage for infections such as furuncles, carbuncles, and abscesses. It also mentions erythrasma and pitted keratolysis as additional bacterial skin infections.

Healthcare

There are several dermatoses that occur during pregnancy or immediately postpartum, in particular polymorphic eruption of pregnancy, pemphigoid gestationis, and atopic eruption of pregnancy. Pruritus due to intrahepatic cholestasis of pregnancy leads to nonspecific skin lesions, including excoriations due to scratching. Impetigo herpetiformis simply represents pustular psoriasis occurring during pregnancy, and this may be related to the relative hypocalcemia of pregnancy. Lastly, there are physiologic changes that occur during pregnancy.

Erythemas

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Urticaria

Ibrahim Farag

Urticaria is characterized by WEALS (hives) or ANGIOEDEMA (swellings, in 10%) or both (in 40%). There are several types of urticaria Spontaneous urticaria Acute spontaneous urticaria Spontaneous wheals and/or angioedema <6 />6 wk Urticarias induced by physical agents dermographic urticaria Eliciting factor: mechanical shearing forces (wheals arising after 1–5 min) Cold contact urticaria Eliciting factor: cold objects/air/fluids/wind Solar urticaria Eliciting factor: UV and/or visible light Delayed pressure urticaria Eliciting factor: vertical pressure (wheals arising with a 3–12 h latency) Heat contact urticaria Eliciting factor: localized heat Hot water bottle Hot drink Vibratory urticaria/angioedema Eliciting factor: vibratory forces, e.g. pneumatic hammer/Jack hammer Other inducible urticarias Contact urticaria Elicitation by contact with urticariogenic substance Aquagenic urticaria Eliciting factor: water Cholinergic urticaria Elicitation by increase of body core temperature due to physical exercises, spicy food, stress Exercise-induced anaphylaxis/urticaria Eliciting factor: physical exercise

Eczematous Dermatoses Part 2

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Eczematous Dermatoses Part 1

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Cutaneous Tuberculosis

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Leprosy

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Bacterial Diseases

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Insects Bites & Stings-Papular Urticaria

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Insects Bites & Stings: can be divided into 2 groups venomous insect such as a bee or wasp, which uses this as a defense mechanism by injecting toxic and painful venom through its stinger. Non-venomous insect bites pierce the skin to feed on blood. This usually results in intense itching. Papular Urticaria: common disorder manifested by chronic or recurrent papules caused by a HYPERSENSITIVITY REACTION to the bites of mosquitoes, fleas, bedbugs, and other insects

Infestations

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INCONTINENTIA PIGMENTI

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Mastocytosis

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Palmoplantar Keratodermas

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Porokeratosis

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CRISPR-Cas9, a revolutionary gene-editing tool, holds immense potential to reshape medicine, agriculture, and our understanding of life. But like any powerful tool, it comes with ethical considerations. Unveiling CRISPR: This naturally occurring bacterial defense system (crRNA & Cas9 protein) fights viruses. Scientists repurposed it for precise gene editing (correction, deletion, insertion) by targeting specific DNA sequences. The Promise: CRISPR offers exciting possibilities: Gene Therapy: Correcting genetic diseases like cystic fibrosis. Agriculture: Engineering crops resistant to pests and harsh environments. Research: Studying gene function to unlock new knowledge. The Peril: Ethical concerns demand attention: Off-target Effects: Unintended DNA edits can have unforeseen consequences. Eugenics: Misusing CRISPR for designer babies raises social and ethical questions. Equity: High costs could limit access to this potentially life-saving technology. The Path Forward: Responsible development is crucial: International Collaboration: Clear guidelines are needed for research and human trials. Public Education: Open discussions ensure informed decisions about CRISPR. Prioritize Safety and Ethics: Safety and ethical principles must be paramount. CRISPR offers a powerful tool for a better future, but responsible development and addressing ethical concerns are essential. By prioritizing safety, fostering open dialogue, and ensuring equitable access, we can harness CRISPR's power for the benefit of all. (2998 characters)

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Pediatric nurses play a vital role in the health and well-being of children. Their responsibilities are wide-ranging, and their objectives can be categorized into several key areas: 1. Direct Patient Care: Objective: Provide comprehensive and compassionate care to infants, children, and adolescents in various healthcare settings (hospitals, clinics, etc.). This includes tasks like: Monitoring vital signs and physical condition. Administering medications and treatments. Performing procedures as directed by doctors. Assisting with daily living activities (bathing, feeding). Providing emotional support and pain management. 2. Health Promotion and Education: Objective: Promote healthy behaviors and educate children, families, and communities about preventive healthcare. This includes tasks like: Administering vaccinations. Providing education on nutrition, hygiene, and development. Offering breastfeeding and childbirth support. Counseling families on safety and injury prevention. 3. Collaboration and Advocacy: Objective: Collaborate effectively with doctors, social workers, therapists, and other healthcare professionals to ensure coordinated care for children. Objective: Advocate for the rights and best interests of their patients, especially when children cannot speak for themselves. This includes tasks like: Communicating effectively with healthcare teams. Identifying and addressing potential risks to child welfare. Educating families about their child's condition and treatment options. 4. Professional Development and Research: Objective: Stay up-to-date on the latest advancements in pediatric healthcare through continuing education and research. Objective: Contribute to improving the quality of care for children by participating in research initiatives. This includes tasks like: Attending workshops and conferences on pediatric nursing. Participating in clinical trials related to child health. Implementing evidence-based practices into their daily routines. By fulfilling these objectives, pediatric nurses play a crucial role in ensuring the optimal health and well-being of children throughout all stages of their development.

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The "ICH Guidelines for Pharmacovigilance" PDF provides a comprehensive overview of the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH) guidelines related to pharmacovigilance. These guidelines aim to ensure that drugs are safe and effective for patients by monitoring and assessing adverse effects, ensuring proper reporting systems, and improving risk management practices. The document is essential for professionals in the pharmaceutical industry, regulatory authorities, and healthcare providers, offering detailed procedures and standards for pharmacovigilance activities to enhance drug safety and protect public health.

India Clinical Trials Market: Industry Size and Growth Trends [2030] Analyzed...

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According to TechSci Research report, "India Clinical Trials Market- By Region, Competition, Forecast & Opportunities, 2030F," the India Clinical Trials Market was valued at USD 2.05 billion in 2024 and is projected to grow at a compound annual growth rate (CAGR) of 8.64% through 2030. The market is driven by a variety of factors, making India an attractive destination for pharmaceutical companies and researchers. India's vast and diverse patient population, cost-effective operational environment, and a large pool of skilled medical professionals contribute significantly to the market's growth. Additionally, increasing government support in streamlining regulations and the growing prevalence of lifestyle diseases further propel the clinical trials market. Growing Prevalence of Lifestyle Diseases The rising incidence of lifestyle diseases such as diabetes, cardiovascular diseases, and cancer is a major trend driving the clinical trials market in India. These conditions necessitate the development and testing of new treatment methods, creating a robust demand for clinical trials. The increasing burden of these diseases highlights the need for innovative therapies and underscores the importance of India as a key player in global clinical research.

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Pubrica’s team of researchers and writers create scientific and medical research articles, which may be important resources for authors and practitioners. Pubrica medical writers assist you in creating and revising the introduction by alerting the reader to gaps in the chosen study subject. Our professionals understand the order in which the hypothesis topic is followed by the broad subject, the issue, and the backdrop. https://pubrica.com/academy/case-study-or-series/how-many-patients-does-case-series-should-have-in-comparison-to-case-reports/

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pchutichetpong

M Capital Group (“MCG”) predicts that with, against, despite, and even without the global pandemic, the medical technology (MedTech) industry shows signs of continuous healthy growth, driven by smaller, faster, and cheaper devices, growing demand for home-based applications, technological innovation, strategic acquisitions, investments, and SPAC listings. MCG predicts that this should reflects itself in annual growth of over 6%, well beyond 2028. According to Chris Mouchabhani, Managing Partner at M Capital Group, “Despite all economic scenarios that one may consider, beyond overall economic shocks, medical technology should remain one of the most promising and robust sectors over the short to medium term and well beyond 2028.” There is a movement towards home-based care for the elderly, next generation scanning and MRI devices, wearable technology, artificial intelligence incorporation, and online connectivity. Experts also see a focus on predictive, preventive, personalized, participatory, and precision medicine, with rising levels of integration of home care and technological innovation. The average cost of treatment has been rising across the board, creating additional financial burdens to governments, healthcare providers and insurance companies. According to MCG, cost-per-inpatient-stay in the United States alone rose on average annually by over 13% between 2014 to 2021, leading MedTech to focus research efforts on optimized medical equipment at lower price points, whilst emphasizing portability and ease of use. Namely, 46% of the 1,008 medical technology companies in the 2021 MedTech Innovator (“MTI”) database are focusing on prevention, wellness, detection, or diagnosis, signaling a clear push for preventive care to also tackle costs. In addition, there has also been a lasting impact on consumer and medical demand for home care, supported by the pandemic. Lockdowns, closure of care facilities, and healthcare systems subjected to capacity pressure, accelerated demand away from traditional inpatient care. Now, outpatient care solutions are driving industry production, with nearly 70% of recent diagnostics start-up companies producing products in areas such as ambulatory clinics, at-home care, and self-administered diagnostics.

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Antibiotic Stewardship by Anushri Srivastava.pptx

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Stewardship is the act of taking good care of something. Antimicrobial stewardship is a coordinated program that promotes the appropriate use of antimicrobials (including antibiotics), improves patient outcomes, reduces microbial resistance, and decreases the spread of infections caused by multidrug-resistant organisms. WHO launched the Global Antimicrobial Resistance and Use Surveillance System (GLASS) in 2015 to fill knowledge gaps and inform strategies at all levels. ACCORDING TO apic.org, Antimicrobial stewardship is a coordinated program that promotes the appropriate use of antimicrobials (including antibiotics), improves patient outcomes, reduces microbial resistance, and decreases the spread of infections caused by multidrug-resistant organisms. ACCORDING TO pewtrusts.org, Antibiotic stewardship refers to efforts in doctors’ offices, hospitals, long term care facilities, and other health care settings to ensure that antibiotics are used only when necessary and appropriate According to WHO, Antimicrobial stewardship is a systematic approach to educate and support health care professionals to follow evidence-based guidelines for prescribing and administering antimicrobials In 1996, John McGowan and Dale Gerding first applied the term antimicrobial stewardship, where they suggested a causal association between antimicrobial agent use and resistance. They also focused on the urgency of large-scale controlled trials of antimicrobial-use regulation employing sophisticated epidemiologic methods, molecular typing, and precise resistance mechanism analysis. Antimicrobial Stewardship(AMS) refers to the optimal selection, dosing, and duration of antimicrobial treatment resulting in the best clinical outcome with minimal side effects to the patients and minimal impact on subsequent resistance. According to the 2019 report, in the US, more than 2.8 million antibiotic-resistant infections occur each year, and more than 35000 people die. In addition to this, it also mentioned that 223,900 cases of Clostridoides difficile occurred in 2017, of which 12800 people died. The report did not include viruses or parasites VISION Being proactive Supporting optimal animal and human health Exploring ways to reduce overall use of antimicrobials Using the drugs that prevent and treat disease by killing microscopic organisms in a responsible way GOAL to prevent the generation and spread of antimicrobial resistance (AMR). Doing so will preserve the effectiveness of these drugs in animals and humans for years to come. being to preserve human and animal health and the effectiveness of antimicrobial medications. to implement a multidisciplinary approach in assembling a stewardship team to include an infectious disease physician, a clinical pharmacist with infectious diseases training, infection preventionist, and a close collaboration with the staff in the clinical microbiology laboratory to prevent antimicrobial overuse, misuse and abuse. to minimize the developme

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Hypertension is a chronic condition of concern due to its role in the causation of coronary heart diseases. Hypertension is a worldwide epidemic and important risk factor for coronary artery disease, stroke and renal diseases. Blood pressure is the force exerted by the blood against the walls of the blood vessels and is sufficient to maintain tissue perfusion during activity and rest. Hypertension is sustained elevation of BP. In adults, HTN exists when systolic blood pressure is equal to or greater than 140mmHg or diastolic BP is equal to or greater than 90mmHg. The

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