Serial debridement is a surgical technique used to treat infected wounds or open fractures. It involves performing multiple debridement procedures over time to remove all non-viable tissue from the wound until only healthy, bleeding tissue remains.
The key aspects of serial debridement include:
- Repeated debridement surgeries are performed, typically every 48-72 hours.
- Each surgery aims to remove more infected, necrotic, or non-viable tissue until the wound base is clean with bleeding tissue.
- Antibiotics are usually administered between procedures to help control the infection as more dead tissue is removed.
- The goal is to eliminate the source of infection and promote healthy granulation
The IOSR Journal of Pharmacy (IOSRPHR) is an open access online & offline peer reviewed international journal, which publishes innovative research papers, reviews, mini-reviews, short communications and notes dealing with Pharmaceutical Sciences( Pharmaceutical Technology, Pharmaceutics, Biopharmaceutics, Pharmacokinetics, Pharmaceutical/Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmacognosy & Phytochemistry, Pharmacology, Pharmaceutical Analysis, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics and Biotechnology of Pharmaceutical Interest........more details on Aim & Scope).
All manuscripts are subject to rapid peer review. Those of high quality (not previously published and not under consideration for publication in another journal) will be published without delay.
Dr. Ahmed M. Adawy
Professor Emeritus, Dept. Oral & Maxillofacial Surg.
Former Dean, Faculty of Dental Medicine
Al-Azhar University
The term “blow out” refers to partial herniation of the orbital contents through one of its walls. This usually occurs via blunt force trauma to the eye. Most often, the orbital floor is fractured in conjunction with the inferior orbital rim “impure” blowout fracture, but “pure” orbital floor fractures, with intact orbital rim can be seen. An extensive and careful history, physical examination, together with CT scans is vital for the diagnosis of orbital floor fractures. The timing of treatment, surgical approaches, and reconstruction of the orbital floor are presented.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
The IOSR Journal of Pharmacy (IOSRPHR) is an open access online & offline peer reviewed international journal, which publishes innovative research papers, reviews, mini-reviews, short communications and notes dealing with Pharmaceutical Sciences( Pharmaceutical Technology, Pharmaceutics, Biopharmaceutics, Pharmacokinetics, Pharmaceutical/Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmacognosy & Phytochemistry, Pharmacology, Pharmaceutical Analysis, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics and Biotechnology of Pharmaceutical Interest........more details on Aim & Scope).
All manuscripts are subject to rapid peer review. Those of high quality (not previously published and not under consideration for publication in another journal) will be published without delay.
Dr. Ahmed M. Adawy
Professor Emeritus, Dept. Oral & Maxillofacial Surg.
Former Dean, Faculty of Dental Medicine
Al-Azhar University
The term “blow out” refers to partial herniation of the orbital contents through one of its walls. This usually occurs via blunt force trauma to the eye. Most often, the orbital floor is fractured in conjunction with the inferior orbital rim “impure” blowout fracture, but “pure” orbital floor fractures, with intact orbital rim can be seen. An extensive and careful history, physical examination, together with CT scans is vital for the diagnosis of orbital floor fractures. The timing of treatment, surgical approaches, and reconstruction of the orbital floor are presented.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
1. 1. What are the risk of the deltoid splitting approach in proximal head fracture ?
A: Injury to the anterior motor branch of the axillary nerve during surgical exposure for
proximal humerus fixation is a concern when using either deltopectoral or deltoid-splitting
approaches. The deltopectoral approach requires substantial soft tissue dissection when
used for fracture fixation, especially with displaced greater tuberosity fragments.
Conversely, the axillary nerve may be more at risk during a deltoid-splitting approach due to
its anatomic location, as it traverses the field of exposure. Several studies have compared
the 2 approaches and found similar clinical, radiographic, and electrophysiological
outcomes. There has been a multitude of studies describing various methods of identifying
the location of the axillary nerve for the deltoid-splitting approach and have documented
various “safe zones” for this exposure.
Traver, J.L. et al. (2016) “Is the axillary nerve at risk during a deltoid-splitting approach for
proximal humerus fractures?,” Journal of Orthopaedic Trauma, 30(5), pp. 240–244.
Available at: https://doi.org/10.1097/bot.0000000000000492.
2. Pls explain the pathway of the Axillary nerve ?
A: Directly inferior to joint capsule, it travels posteriorly with post. circumfl ex humeral art.
thru quadrangular space, then bends anteriorly approx. 5cm distal to acromion. It can be
injured in glenohumeral dislocations and lateral approaches.
Axillary nerve is one of the terminal branches of posterior cord of brachial plexus, which is
most commonly injured during numerous orthopaedic surgeries, during shoulder
dislocation & rotator cuff tear. All these possible iatrogenic injuries are because of lack of
awareness of anatomical variations of the nerve. Therefore, it is very much necessary to
explore its possible variations and guide the surgeons to enhance the better clinical
outcome by reducing the risk and complications.
Gurushantappa, P.K. (2015) “Anatomy of axillary nerve and its clinical importance: A cadaveric
study,” JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH [Preprint]. Available
at: https://doi.org/10.7860/jcdr/2015/12349.5680.
2. 1. Why is CT scan necessary after post hip reduction ?
Recent articles and textbooks of orthopaedic traumatology recommend routine
computed tomography (CT) scans after successful reduction of simple posterior hip
dislocations. This is based on the belief that CT, even in cases with concentric
reductions, may identify fractures or intraarticular loose bodies not apparent on
standard radiographs. This study was conducted to assess the usefulness of CT after
concentric reduction of simple posterior hip dislocations. The hospital database was
searched for all traumatic hip dislocations in the past 4 years. Charts and radiographs
were reviewed, and only patients with simple posterior hip dislocations (no
acetabular or femoral head fractures) and a concentric reduction identified on plain
radiographs were included. Twenty-three patients who met these criteria and had
subsequent CT scans to evaluate the hip joint were identified. CT scans confirmed
the concentric reduction in all patients.
Frick, S.L. and Sims, S.H. (1995) “Is computed tomography useful after simple posterior
hip dislocation?,” Journal of Orthopaedic Trauma, 9(5), pp. 388–391. Available at:
https://doi.org/10.1097/00005131-199505000-00005.
2. What is the dangerous of Smith Petersen approach ?
Probably the most commonly injured structure with this approach is the lateral femoral
cutaneous nerve, which usually exits the pelvis close to the anterosuperior iliac spine and
runs in an oblique course down the thigh. The nerve is typically found in the lateral flap of
this approach, but if it crosses more medially than is normal, it may need to be sacrificed and
allowed to retract into the pelvis. The other structures at risk are the femoral nerve and artery.
The nerve sits more laterally than the artery and is encountered first. Additionally, it gives off
branches to the sartorius, and if there is any dissection along the medial aspect of the
sartorius, that muscle can be denervated. This nerve is anterior to the pectineus muscle,
which is generally used to protect the nerve. It may branch fairly high, sending offits motor
branches to the sartorius and the rectus.
Atlas of Orthopaedic Surgical ExposuresDOI: 10.1055/b-0034-39502
3. 1. The risk of beach chair position in proximal humeral head surgery ?
In the beach-chair position, the patient is placed supine on a dedicated
operating table (associated with additional costs) and then the table is
maneuvered into the desired semi-sitting position. Key considerations include
placing a cushion beneath the knees prior to elevating the trunk, maintaining
neutral alignment of the head, and using a positioning device to control the
arm. Cerebral hypoperfusion is recognised as one of the most serious
complications during arthroscopy in the beach-chair position and occurs in up
to 80% of patients.
a. Risk of cerebral hypoperfusion.
b. Potential mechanical block to using the arthroscope due to the supportive device
located at the posterior aspect of the medial border of the scapula.
c. Risk of eye injury with facemask.
Burkhart, S.S. and Nottage, W.M. (2001) “Current concepts of rotator cuff repair,” Advanced
Arthroscopy, pp. 81–88. Available at: https://doi.org/10.1007/978-0-387-21541-9_10.
2. How to prevent “screw cut out” complications in proximal humeral fracture ?
It was noted that this complication is more common in patients > 60 years in whom
osteoporotic bone is more likely to be found. We believe that the concept of subchondral
screw fixation (as in load bearing joint periarticular fractures such as femoral neck fractures)
is a misuse of the locking design for proximal humerus fractures in which rotator cuff tissue
integrity often exceeds that of the metaphyseal bone of the humeral tuberosities. For this
reason, we use short, divergent locking screws and suture fixation to minimize the risk of
varus malunion, plate failure, and intra-articular screw penetration. We have treated 53
proximal humerus fractures at our institution with this fixation technique. None have had
intra-articular screw penetration or cut-out and only two patients had an asymptomatic
varus malunion at an average follow-up of 16 months. It is our belief that such a technique
reduces the incidence of screw penetration into the glenohumeral joint and provides stable
fixation for healing. Further biomechanical and long-term clinical data are necessary to
substantiate these hypotheses.
Namdari, S. et al. (2012) “Fixation strategies to prevent screw cut-out and malreduction in
proximal humeral fracture fixation,” Clinics in Orthopedic Surgery, 4(4), p. 321. Available
at: https://doi.org/10.4055/cios.2012.4.4.321.
4. Deltopectoral Aprroach:
Advantageous:
- This approach has the advantage of allowing the surgeon to work through an internervous plane with a wide
exposure.
- This approach also allows the surgeon to convert from ORIF to hemiarthroplasty if required.
- The deltopectoral approach however requires significant soft tissue dissection to gain access to the lateral aspect
of the proximal humerus for fracture reduction and plate placement.
Disadvantageous:
- The musculocutaneous nerve is at risk from medial retraction when performing the deltopectoral approach. The
musculocutaneous nerve originates from the lateral cord of the brachial plexus. The most proximal motor branch
to the coracobrachialis muscle is located about 3 to 4 cm distal to the tip of the coracoid, being less than 5 cm in
75% of cases.
Deltoid Splitting Aproach:
Advantageous:
- The deltoid-splitting approach is favored by several authors since it allows a direct approach through the
fracture site between the greater and lesser tuberosities.
- allows for a more direct manipulation of the humeral head, as well as allowing plate and screw placement in
line with the incision
Disadvantageous:
- The deltoid-splitting approach has two major disadvantages.In anteroinferior fracture dislocations, the humeral
head fragment may not be accessible through this approach. In addition, the terminal anterior branch of the
axillary nerve may be inadvertently damaged thereby leading to potential deltoid dysfunction.
- the potential for injury to the anterior branch of the axillary nerve is its main disadvantage, as it may lead to
anterior deltoid dysfunction.