THIS presentation gives a brief overview of what peptic ulcer is and how h. pylori, NSAID's and stress cause peptic ulcer. it is presented in a diagrammatic view which clears the concept for its causes. It will be helpful for the people studying pathophysiology of diseases.

1. PEPTIC ULCER
And
Its causes
ESHIKA JAIN
PHARM D 2ND YEAR
1950951003

2. Peptic Ulcer
• Peptic ulcer is a sore that
develops on the lining of the
oesophagus, stomach or small
intestine.
• It is the imbalance between
defensive factors and the
aggressive factors.
• Ulcers occur when stomach acid
damages the lining of the
digestive tract.
Duodenum
PEPTIC ULCER
PEPTIC ULCER
STOMACH
OESOPHAGUS

3. H PYLORI BACTERIA
The H. pylori bacteria weakens the protective mucous coating of
the stomach and duodenum.
thus allowing acid to get through to the sensitive lining beneath.
Both the acid and the bacteria irritate the lining
cause a sore, or ulcer.

4. NORMAL STOMACH PEPTIC ULCER BY H. PYLORI
BACTERIA
PEPTIC ULCER
H PYLORI

5. NON STEROIDAL ANTI- INFLAMMATORY DRUGS AND
STRESS..
Non steroidal anti inflammatory
drugs (NSAID’S)
STOMACH
Stress, alcohol,
caffeine stimulate
gastric acid secretion
Peptic ulcer
Peptic ulcer may lead to bleeding or
perforation