This document provides a summary of 5 free online drug information resources that are useful for pharmacists to include in their toolbox. It briefly describes the main drug databases and information available from DailyMed, MedlinePlus, the FDA website, the CDC website, and the DEA website. These resources provide information on approved drugs and packaging inserts, consumer health information, drug approvals and recalls, vaccines and health reports, and controlled substances. The summary encourages pharmacists to utilize these free online tools for drug information needs.
Potential nutraceuticals and their functionHazrat Ali
The document discusses potential nutraceuticals found in common foods in Bangladesh. It begins by defining nutraceuticals and their potential health benefits. One nutraceutical discussed in detail is capsaicin, the active component in chili peppers. Capsaicin is found in large quantities in chili peppers and has several potential health benefits including cancer treatment, decreasing cluster headaches, pain relief, treating psoriasis, aiding diabetes management, and lowering blood pressure. The document provides sources and evidence from studies on the health effects of capsaicin.
2014 Report: Medicines in Development for DiabetesPhRMA
Nearly 26 million Americans are affected by diabetes—including 7 million people who are unaware they have the disease. One of the top 10 causes of death in the United States, diabetes has far-reaching implications for patients and their families and our health care system.
Biopharmaceutical Research Companies Are Developing 180 Medicines to Treat Diabetes and Related Conditions.
The Agency for Healthcare Research and Quality (AHRQ) released a series of eight new Spanish language guides for patients on various health topics and conditions. The guides provide information to help Spanish speakers understand treatment options for high cholesterol, osteoarthritis of the knee, gestational diabetes, breast biopsies, atrial fibrillation, reducing breast cancer risk, and inducing labor. They summarize evidence on treatment effectiveness and risks so patients can discuss options with their doctors. AHRQ also previously released guides on nine other health topics. The guides aim to improve healthcare quality and address disparities for Hispanic patients.
Contrave is an anti-obesity drug that combines naltrexone and bupropion. The document provides an overview of Contrave and compares it to other FDA-approved anti-obesity medications. It summarizes results from four clinical trials of Contrave, which showed average weight losses of 5-9% compared to 1-2% for placebo after 1 year of treatment. The document also reviews Contrave's mechanism of action, dosing, and side effect profile. It concludes that Contrave provides effective long-term weight management and compares its efficacy and safety profile to other anti-obesity medications.
Anaya eugenio et al, 2014 - hypoglycemic properties of some preparations and ...Juliana Braga
This research paper examines the hypoglycemic properties of Artemisia ludoviciana, a plant used in traditional Mexican medicine to treat diabetes. Acute and oral glucose/sucrose tolerance tests were conducted on normal and diabetic mice using different preparations of A. ludoviciana, including an essential oil, organic extract, and infusion. The organic extract and infusion showed hypoglycemic effects in diabetic mice. Phytochemical analysis of the infusion isolated compounds including eupatilin, jaceosidin, arglanin, salvinine, and 3,5-dicaffeoylquinic acid. Biological testing found arglanin and eupatilin have hypoglycemic effects. The
This document summarizes information about ADHD, including prevalence, treatment options, controversies, and alternative therapies. It then provides an overview of Nurture & Clarity, a herbal supplement designed to treat ADHD symptoms. Key points:
- ADHD is one of the most common childhood psychiatric disorders, affecting 4-5 million children in the US. Approximately 50-70% of cases persist into adulthood.
- While stimulant medications are most commonly prescribed, their side effects and potential for abuse are controversial. There is a need for safer, non-stimulant treatment options.
- Nurture & Clarity is a herbal supplement produced according to pharmaceutical standards. A clinical trial found
Synthetic Drugs/Hormones - Boon or Bane- Concept of Dooshivisha and Gara VishaIJARIIT
21st century is the world full of synthetics and everyone are living in the influence of synthetic substances. Altered life
styles, food habits and irregular sleep pattern had resulted not only Non communicable disease but also resulting in reduced
immunity and is risking the person more for infections. Pharma Industry has grown as big as hierarchy in recent centauries
and introduces new chemical molecules quoting as capable for treating diabetes, hypertension etc. But bitter truth is prolonged
usage these medications itself has adverse effect on liver and kidneys causes hepatotoxicity and nephrotoxicity or organs
specific toxicity.
Potential nutraceuticals and their functionHazrat Ali
The document discusses potential nutraceuticals found in common foods in Bangladesh. It begins by defining nutraceuticals and their potential health benefits. One nutraceutical discussed in detail is capsaicin, the active component in chili peppers. Capsaicin is found in large quantities in chili peppers and has several potential health benefits including cancer treatment, decreasing cluster headaches, pain relief, treating psoriasis, aiding diabetes management, and lowering blood pressure. The document provides sources and evidence from studies on the health effects of capsaicin.
2014 Report: Medicines in Development for DiabetesPhRMA
Nearly 26 million Americans are affected by diabetes—including 7 million people who are unaware they have the disease. One of the top 10 causes of death in the United States, diabetes has far-reaching implications for patients and their families and our health care system.
Biopharmaceutical Research Companies Are Developing 180 Medicines to Treat Diabetes and Related Conditions.
The Agency for Healthcare Research and Quality (AHRQ) released a series of eight new Spanish language guides for patients on various health topics and conditions. The guides provide information to help Spanish speakers understand treatment options for high cholesterol, osteoarthritis of the knee, gestational diabetes, breast biopsies, atrial fibrillation, reducing breast cancer risk, and inducing labor. They summarize evidence on treatment effectiveness and risks so patients can discuss options with their doctors. AHRQ also previously released guides on nine other health topics. The guides aim to improve healthcare quality and address disparities for Hispanic patients.
Contrave is an anti-obesity drug that combines naltrexone and bupropion. The document provides an overview of Contrave and compares it to other FDA-approved anti-obesity medications. It summarizes results from four clinical trials of Contrave, which showed average weight losses of 5-9% compared to 1-2% for placebo after 1 year of treatment. The document also reviews Contrave's mechanism of action, dosing, and side effect profile. It concludes that Contrave provides effective long-term weight management and compares its efficacy and safety profile to other anti-obesity medications.
Anaya eugenio et al, 2014 - hypoglycemic properties of some preparations and ...Juliana Braga
This research paper examines the hypoglycemic properties of Artemisia ludoviciana, a plant used in traditional Mexican medicine to treat diabetes. Acute and oral glucose/sucrose tolerance tests were conducted on normal and diabetic mice using different preparations of A. ludoviciana, including an essential oil, organic extract, and infusion. The organic extract and infusion showed hypoglycemic effects in diabetic mice. Phytochemical analysis of the infusion isolated compounds including eupatilin, jaceosidin, arglanin, salvinine, and 3,5-dicaffeoylquinic acid. Biological testing found arglanin and eupatilin have hypoglycemic effects. The
This document summarizes information about ADHD, including prevalence, treatment options, controversies, and alternative therapies. It then provides an overview of Nurture & Clarity, a herbal supplement designed to treat ADHD symptoms. Key points:
- ADHD is one of the most common childhood psychiatric disorders, affecting 4-5 million children in the US. Approximately 50-70% of cases persist into adulthood.
- While stimulant medications are most commonly prescribed, their side effects and potential for abuse are controversial. There is a need for safer, non-stimulant treatment options.
- Nurture & Clarity is a herbal supplement produced according to pharmaceutical standards. A clinical trial found
Synthetic Drugs/Hormones - Boon or Bane- Concept of Dooshivisha and Gara VishaIJARIIT
21st century is the world full of synthetics and everyone are living in the influence of synthetic substances. Altered life
styles, food habits and irregular sleep pattern had resulted not only Non communicable disease but also resulting in reduced
immunity and is risking the person more for infections. Pharma Industry has grown as big as hierarchy in recent centauries
and introduces new chemical molecules quoting as capable for treating diabetes, hypertension etc. But bitter truth is prolonged
usage these medications itself has adverse effect on liver and kidneys causes hepatotoxicity and nephrotoxicity or organs
specific toxicity.
This document discusses nutraceuticals and their potential role in medicine. It defines key terms like dietary supplements, nutraceuticals, and functional foods. It outlines the growing interest in using foods and herbal remedies to promote health and prevent disease. Research is strengthening the evidence that certain nutrients may support health and longevity by reducing oxidative stress and inflammation associated with aging. The field of nutrigenomics also aims to develop personalized nutrition approaches based on individual genetics. Overall the document argues that nutraceuticals have potential medical benefits but more research is still needed.
Ellen Kamhi PhD RN and Eugene Zampieron ND . All health providers should be aware of the possibility of interactions between pharmaceutical agents and botanical supplements. This is an introduction to a full course on Drug Nutrient Depletions and Herb Drug Interaction. In this intro, we describe drugs that can cause depletions through a variety of biochemical mechanisms. Depletion of nutrients can lead to alterations in physiology leading to side effects, symptoms or other conditions and disease.
We also review significant herb/drug interactions, and provide a review of databases and information relating to this topic.
Journal of Schizophrenia Research is a peer-reviewed, open access journal published by Austin Publishers. It provides easy access to high quality Manuscripts in all related aspects of a mental disorder often characterized by abnormal social behavior and failure to recognize what is real with common symptoms including false beliefs, auditory hallucinations, confused or unclear thinking, inactivity, and reduced social engagement and emotional expression. The journal focuses upon the latest research in finding causes, understanding mechanisms, diagnosis, prevention, management, prognosis, epidemiology, ancestral history and treatment of schizophrenia.
Austin Publishing Group is a successful host of more than hundred peer reviewed, open access journals in various fields of science and medicine with intent to bridge the gap between academia and research access.
Journal of Schizophrenia Research accepts original research articles, review articles, case reports, mini reviews, rapid communication, opinions and editorials on all related aspects of schizophrenia including, finding causes, understanding mechanisms, diagnosis, prevention, management, prognosis, epidemiology, ancestral history and its treatment.
Herbal products in canada how safe are theyNazeer Mohd
Herbal products sold in Canada are largely unregulated as they are exempt from the drug review process if not registered as drugs. This places consumers at risk of side effects from adulterated or ineffective herbal products. While perceived as natural and safe, herbal therapies can be harmful, especially when used to replace conventional medical treatment. Physicians need to be aware of potential issues with herbal product use in order to advise patients.
Obesity and hyperlipidemia is international /worldwide problem causing heart disease leading to major predisposing factor for morbidity and death. Conventional medicine used in allopathy include statins, fibrates, niacin and resins but are going to defame due to their adverse effects. Herbal medicine ginger has proved itself as one of the potent anti hyperlipidemic and anti obesity herb with least adverse effects. We did try to compare its hypolipidemic effects with placebo effects when used in mild to moderate hyperlipidemic patients. It was placebo-controlled single blind research study. Research was conducted at National hospital, Lahore, from July to November 2016. Consent was taken from sixty hyperlipidemic patients age range from 25 to 60 years. Both gender male and female patients were enrolled. Patients were randomly divided in two groups, 30 patients were on drug ginger pasted-powder advised to take 5 grams in divided doses with their normal diet for the period of three months. Thirty patients were on placebo pasted-wheat powder, with same color as of ginger powder, advised to take 5 grams in divided doses with their normal diet for the period of three months. Their base line lipid profile and body weight was recorded at start of treatment and were advised to come for check-up, fortnightly.
International Journal of Medical Science in Clinical Research and Review Vol 03, Issue 02,April – 2020 Page |
229
When duration of study was over, their lipid profile and body weight was measured and compared statistically with pre-treatment values. Three months treatment with 5 grams of ginger decreased total cholesterol from 233.11±1.53 mg/dl to 198.44±1.23 mg/dl, LDL cholesterol reduced from 202.21±1.88 mg/dl to 187.72± 1.98 mg/dl, reduced body weight from 76.01±2.66 kg to 72.80±1.87 kg. Both plasma total cholesterol and LDL cholesterol reduction was statistically significant, but body weight decrease was non-significant when analyzed biostatistically.
This document provides guidance from the National Heart, Lung, and Blood Institute on lowering blood pressure through the DASH (Dietary Approaches to Stop Hypertension) eating plan. It describes two major studies that showed following the DASH eating plan, which emphasizes fruits, vegetables, and low-fat dairy while limiting fats and sweets, can significantly reduce blood pressure. The DASH plan calls for a certain number of daily servings from various food groups depending on calorie needs. It states the DASH plan, combined with reducing sodium intake, provides the greatest blood pressure lowering effects.
Genetics in medicine 2014, Vol. 16, Nr. 2 - Phenylalanine hydroxylase deficie...RAMONARICLEA1
Phenylalanine hydroxylase deficiency, traditionally known as phenylketonuria (PKU), was the first inborn error of metabolism identified through population screening. Early treatment through dietary phenylalanine restriction prevents major clinical issues, but new neurodevelopmental problems have emerged. This guideline reviews evidence on diagnosing and treating PKU, recommending life-long treatment to maintain blood phenylalanine levels between 120-360 micromols/L. Current treatment relies on low-protein medical foods, though pharmacotherapy is developing. Significant evidence gaps remain regarding optimal long-term therapies and outcomes.
Herbal Medicine : Effect of clinical laboratory test Sarvan Mani
This document summarizes how herbal medicines can interfere with clinical laboratory tests in three main ways: direct assay interference, physiological effects of toxicity/enzyme induction, and contamination with undisclosed drugs. It provides the specific example of how the Chinese herbal medicine Chan Su can cause falsely elevated digoxin levels due to cross-reactivity in immunoassays that use polyclonal antibodies against digoxin. The document also notes that herbal medicines are widely used but loosely regulated in the United States and discusses the importance of communication between clinicians and laboratories when interpreting abnormal laboratory results in patients using herbal medicines.
This daily health update email contains summaries of recent research on potential alternative treatments for depression, rising deaths due to high blood pressure, reducing liver cancer risk through limiting alcohol and maintaining a healthy weight, midlife fitness reducing cancer risk in men, unstable shoes possibly helping back pain patients, and planning for children in emergencies. The email concludes with a quote about not pretending second rate is first rate.
This daily health update email contains summaries of recent studies on various health topics:
1) A study found that about 15% of adults diagnosed with coronary artery disease suffered from depression, which is higher than the general population, and those with depression were more likely to die in the following decade.
2) Researchers discovered that patients with osteoarthritis have an elevated risk of stroke, with the risk being nearly four times greater for those with severe osteoarthritis.
3) A USDA report notes that vegetarian meals can be satisfying if they include lean proteins like beans as well as veggie-based foods like pizza, pasta, and stir fries.
The document discusses open data about medicines and drugs. It notes that there are over 4,600 known active pharmaceutical ingredients, including about 1,800 that are currently FDA-approved and marketed in the US. DrugCentral is an online resource that contains information on these drugs and their targets, with data on over 667 human proteins and 226 pathogen proteins that FDA-approved drugs act on. The document advocates for making more drug data openly available to further scientific understanding of medicines and discovery efforts.
1) Many people have made consuming drugs a daily habit similar to eating food, as pharmacies are filled with various tablets, capsules, and suspensions in different colors and flavors.
2) A journalist asked about an expensive drug prescribed to his wife that could not be identified in any pharmacology references. It was found to be a dietary supplement containing a chemical similar to the hormone estrogen, though studies show it does not have the same effects and may increase breast cancer risk.
3) There are now hundreds of unknown pill and suspensions being prescribed and sold based on claims of supporting health in various ways, but most are introduced as natural to falsely imply safety despite lack of evidence. Proper action needs to be taken to
This document provides a 3-sentence summary of the consensus statement on the comprehensive type 2 diabetes management algorithm:
The consensus statement presents an updated algorithm for the comprehensive management of type 2 diabetes that incorporates new therapies, management approaches, and clinical data. The algorithm is intended to guide clinicians in developing individualized treatment plans considering a patient's risks, complications, and preferences. It addresses lifestyle therapy, obesity, prediabetes, glucose control, hypertension management, dyslipidemia management, and the attributes and principles for selecting antihyperglycemic therapies.
Rare Diseases: A Report on Orphan Drugs in the PipelinePhRMA
Rare diseases, when taken together, are not that rare at all. In fact, according to the National Institutes of Health (NIH), 30 million Americans have one of the nearly 7,000 diseases that are officially deemed “rare” because alone they each affect fewer than 200,000 people in the United States.
Benefits and Effect of Fenugreek Seeds in the prevention and the management o...IRJET Journal
This document summarizes research on the benefits of fenugreek seeds in the prevention and management of type 2 diabetes. It discusses how fenugreek contains fiber and other compounds that can reduce blood sugar and cholesterol levels. Several studies reviewed showed fenugreek supplementation lowered fasting blood glucose, post-meal blood glucose, and HbA1c levels in people with diabetes or prediabetes. The document concludes that fenugreek may help control blood sugar through multiple mechanisms and represents a potentially inexpensive treatment option, especially in developing countries where diabetes is a growing problem.
Pakistan Pharma Career Door Newsletter ,Issue 4, Volume 4Javeriya_PPCD
The European Medicines Agency's Committee on Medicinal Products for Human Use (CHMP) has recommended granting marketing authorization for Trimbow (Chiesi Farmaceutici S.p.A., Italy), a combination of three inhaled medications, for the maintenance treatment of adults with moderate to severe chronic obstructive pulmonary disease (COPD) who do not respond adequately to a combination of an inhaled corticosteroid and a long-acting β2-agonist. Trimbow contains beclometasone dipropionate, formoterol fumarate dihydrate, and glycopyrronium bromide to reduce lung inflammation, relax bronchial smooth muscle and dilate the airways. The triple-
Rasamanikya is a excellent preparation in the field of Rasashastra, it is used in various Kushtha Roga, Shwasa, Vicharchika, Bhagandara, Vatarakta, and Phiranga Roga. In this article Preparation& Comparative analytical profile for both Formulationon i.e Rasamanikya prepared by Kushmanda swarasa & Churnodhaka Shodita Haratala. The study aims to provide insights into the comparative efficacy and analytical aspects of these formulations for enhanced therapeutic outcomes.
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This document discusses nutraceuticals and their potential role in medicine. It defines key terms like dietary supplements, nutraceuticals, and functional foods. It outlines the growing interest in using foods and herbal remedies to promote health and prevent disease. Research is strengthening the evidence that certain nutrients may support health and longevity by reducing oxidative stress and inflammation associated with aging. The field of nutrigenomics also aims to develop personalized nutrition approaches based on individual genetics. Overall the document argues that nutraceuticals have potential medical benefits but more research is still needed.
Ellen Kamhi PhD RN and Eugene Zampieron ND . All health providers should be aware of the possibility of interactions between pharmaceutical agents and botanical supplements. This is an introduction to a full course on Drug Nutrient Depletions and Herb Drug Interaction. In this intro, we describe drugs that can cause depletions through a variety of biochemical mechanisms. Depletion of nutrients can lead to alterations in physiology leading to side effects, symptoms or other conditions and disease.
We also review significant herb/drug interactions, and provide a review of databases and information relating to this topic.
Journal of Schizophrenia Research is a peer-reviewed, open access journal published by Austin Publishers. It provides easy access to high quality Manuscripts in all related aspects of a mental disorder often characterized by abnormal social behavior and failure to recognize what is real with common symptoms including false beliefs, auditory hallucinations, confused or unclear thinking, inactivity, and reduced social engagement and emotional expression. The journal focuses upon the latest research in finding causes, understanding mechanisms, diagnosis, prevention, management, prognosis, epidemiology, ancestral history and treatment of schizophrenia.
Austin Publishing Group is a successful host of more than hundred peer reviewed, open access journals in various fields of science and medicine with intent to bridge the gap between academia and research access.
Journal of Schizophrenia Research accepts original research articles, review articles, case reports, mini reviews, rapid communication, opinions and editorials on all related aspects of schizophrenia including, finding causes, understanding mechanisms, diagnosis, prevention, management, prognosis, epidemiology, ancestral history and its treatment.
Herbal products in canada how safe are theyNazeer Mohd
Herbal products sold in Canada are largely unregulated as they are exempt from the drug review process if not registered as drugs. This places consumers at risk of side effects from adulterated or ineffective herbal products. While perceived as natural and safe, herbal therapies can be harmful, especially when used to replace conventional medical treatment. Physicians need to be aware of potential issues with herbal product use in order to advise patients.
Obesity and hyperlipidemia is international /worldwide problem causing heart disease leading to major predisposing factor for morbidity and death. Conventional medicine used in allopathy include statins, fibrates, niacin and resins but are going to defame due to their adverse effects. Herbal medicine ginger has proved itself as one of the potent anti hyperlipidemic and anti obesity herb with least adverse effects. We did try to compare its hypolipidemic effects with placebo effects when used in mild to moderate hyperlipidemic patients. It was placebo-controlled single blind research study. Research was conducted at National hospital, Lahore, from July to November 2016. Consent was taken from sixty hyperlipidemic patients age range from 25 to 60 years. Both gender male and female patients were enrolled. Patients were randomly divided in two groups, 30 patients were on drug ginger pasted-powder advised to take 5 grams in divided doses with their normal diet for the period of three months. Thirty patients were on placebo pasted-wheat powder, with same color as of ginger powder, advised to take 5 grams in divided doses with their normal diet for the period of three months. Their base line lipid profile and body weight was recorded at start of treatment and were advised to come for check-up, fortnightly.
International Journal of Medical Science in Clinical Research and Review Vol 03, Issue 02,April – 2020 Page |
229
When duration of study was over, their lipid profile and body weight was measured and compared statistically with pre-treatment values. Three months treatment with 5 grams of ginger decreased total cholesterol from 233.11±1.53 mg/dl to 198.44±1.23 mg/dl, LDL cholesterol reduced from 202.21±1.88 mg/dl to 187.72± 1.98 mg/dl, reduced body weight from 76.01±2.66 kg to 72.80±1.87 kg. Both plasma total cholesterol and LDL cholesterol reduction was statistically significant, but body weight decrease was non-significant when analyzed biostatistically.
This document provides guidance from the National Heart, Lung, and Blood Institute on lowering blood pressure through the DASH (Dietary Approaches to Stop Hypertension) eating plan. It describes two major studies that showed following the DASH eating plan, which emphasizes fruits, vegetables, and low-fat dairy while limiting fats and sweets, can significantly reduce blood pressure. The DASH plan calls for a certain number of daily servings from various food groups depending on calorie needs. It states the DASH plan, combined with reducing sodium intake, provides the greatest blood pressure lowering effects.
Genetics in medicine 2014, Vol. 16, Nr. 2 - Phenylalanine hydroxylase deficie...RAMONARICLEA1
Phenylalanine hydroxylase deficiency, traditionally known as phenylketonuria (PKU), was the first inborn error of metabolism identified through population screening. Early treatment through dietary phenylalanine restriction prevents major clinical issues, but new neurodevelopmental problems have emerged. This guideline reviews evidence on diagnosing and treating PKU, recommending life-long treatment to maintain blood phenylalanine levels between 120-360 micromols/L. Current treatment relies on low-protein medical foods, though pharmacotherapy is developing. Significant evidence gaps remain regarding optimal long-term therapies and outcomes.
Herbal Medicine : Effect of clinical laboratory test Sarvan Mani
This document summarizes how herbal medicines can interfere with clinical laboratory tests in three main ways: direct assay interference, physiological effects of toxicity/enzyme induction, and contamination with undisclosed drugs. It provides the specific example of how the Chinese herbal medicine Chan Su can cause falsely elevated digoxin levels due to cross-reactivity in immunoassays that use polyclonal antibodies against digoxin. The document also notes that herbal medicines are widely used but loosely regulated in the United States and discusses the importance of communication between clinicians and laboratories when interpreting abnormal laboratory results in patients using herbal medicines.
This daily health update email contains summaries of recent research on potential alternative treatments for depression, rising deaths due to high blood pressure, reducing liver cancer risk through limiting alcohol and maintaining a healthy weight, midlife fitness reducing cancer risk in men, unstable shoes possibly helping back pain patients, and planning for children in emergencies. The email concludes with a quote about not pretending second rate is first rate.
This daily health update email contains summaries of recent studies on various health topics:
1) A study found that about 15% of adults diagnosed with coronary artery disease suffered from depression, which is higher than the general population, and those with depression were more likely to die in the following decade.
2) Researchers discovered that patients with osteoarthritis have an elevated risk of stroke, with the risk being nearly four times greater for those with severe osteoarthritis.
3) A USDA report notes that vegetarian meals can be satisfying if they include lean proteins like beans as well as veggie-based foods like pizza, pasta, and stir fries.
The document discusses open data about medicines and drugs. It notes that there are over 4,600 known active pharmaceutical ingredients, including about 1,800 that are currently FDA-approved and marketed in the US. DrugCentral is an online resource that contains information on these drugs and their targets, with data on over 667 human proteins and 226 pathogen proteins that FDA-approved drugs act on. The document advocates for making more drug data openly available to further scientific understanding of medicines and discovery efforts.
1) Many people have made consuming drugs a daily habit similar to eating food, as pharmacies are filled with various tablets, capsules, and suspensions in different colors and flavors.
2) A journalist asked about an expensive drug prescribed to his wife that could not be identified in any pharmacology references. It was found to be a dietary supplement containing a chemical similar to the hormone estrogen, though studies show it does not have the same effects and may increase breast cancer risk.
3) There are now hundreds of unknown pill and suspensions being prescribed and sold based on claims of supporting health in various ways, but most are introduced as natural to falsely imply safety despite lack of evidence. Proper action needs to be taken to
This document provides a 3-sentence summary of the consensus statement on the comprehensive type 2 diabetes management algorithm:
The consensus statement presents an updated algorithm for the comprehensive management of type 2 diabetes that incorporates new therapies, management approaches, and clinical data. The algorithm is intended to guide clinicians in developing individualized treatment plans considering a patient's risks, complications, and preferences. It addresses lifestyle therapy, obesity, prediabetes, glucose control, hypertension management, dyslipidemia management, and the attributes and principles for selecting antihyperglycemic therapies.
Rare Diseases: A Report on Orphan Drugs in the PipelinePhRMA
Rare diseases, when taken together, are not that rare at all. In fact, according to the National Institutes of Health (NIH), 30 million Americans have one of the nearly 7,000 diseases that are officially deemed “rare” because alone they each affect fewer than 200,000 people in the United States.
Benefits and Effect of Fenugreek Seeds in the prevention and the management o...IRJET Journal
This document summarizes research on the benefits of fenugreek seeds in the prevention and management of type 2 diabetes. It discusses how fenugreek contains fiber and other compounds that can reduce blood sugar and cholesterol levels. Several studies reviewed showed fenugreek supplementation lowered fasting blood glucose, post-meal blood glucose, and HbA1c levels in people with diabetes or prediabetes. The document concludes that fenugreek may help control blood sugar through multiple mechanisms and represents a potentially inexpensive treatment option, especially in developing countries where diabetes is a growing problem.
Pakistan Pharma Career Door Newsletter ,Issue 4, Volume 4Javeriya_PPCD
The European Medicines Agency's Committee on Medicinal Products for Human Use (CHMP) has recommended granting marketing authorization for Trimbow (Chiesi Farmaceutici S.p.A., Italy), a combination of three inhaled medications, for the maintenance treatment of adults with moderate to severe chronic obstructive pulmonary disease (COPD) who do not respond adequately to a combination of an inhaled corticosteroid and a long-acting β2-agonist. Trimbow contains beclometasone dipropionate, formoterol fumarate dihydrate, and glycopyrronium bromide to reduce lung inflammation, relax bronchial smooth muscle and dilate the airways. The triple-
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Pakistan Pharma Career Door Newsletter - Vol 2, Issue 2
1. Drug information references
play an important role in phar-
macy practice. Check out these
5 online resources to add to
your drug information toolbox!
1-DailyMed
DailyMed is a one-stop-shop
that contains more than 92,000
drug listings including US Food
and Drug Administration (FDA)
approved package inserts. Addi-
tionally, you can report adverse
events to the FDA’s MedWatch
program. If you need to identify
a medication, then you can do
so through the ID tool known as
Pillbox.
2-MedlinePlus
MedlinePlus is a great consumer
health information resource
published by the National Li-
brary of Medicine and available
both in English and Spanish
languages. MedlinePlus con-
tains information on prescrip-
tion and over-the-counter medi-
cations written in lay language.
Herbal product information is
also available through the Na-
tional Center for Complemen-
tary and Integrative Health.
3-FDA
The FDA website contains a
plethora of information that will
help keep you up-to-date. You
can also register to receive up-
dates on new medication ap-
provals and drug recalls. Check
out the newly designed Ap-
proved Drug Products with
Therapeutic Equivalence
Evaluations, also known as the
Orange Book. It has been up-
dated to enable you to search
the resource more efficiently.
The Orange Book shows prod-
ucts that are therapeutically
equivalent for generic drug
substitution.
4-Centers for Disease Con-
trol and Prevention (CDC)
The CDC is the go to resource
for vaccine information. Provide
parents with childhood vaccine
charts. The monthly published
Vitalsigns report provides perti-
nent information on a variety of
health topics including HIV and
injection drug use, prescription
drug abuse, and food safety.
5-Drug Enforcement Ad-
ministration (DEA)
The DEA website provides up-
to-date information on con-
trolled substances that will help
you stay current with federal
laws and regulations. It includes
resources for drug disposal and
the latest reports such as the
2016 National Drug Threat
Assessment. The Question and
Answers tab provides valuable
information on various con-
trolled substance matters in-
cluding prescription drug moni-
toring programs, DEA Form
222, and electronic prescrip-
tions.
Best of luck on your
drug information quest!
Volume 2, Issue 2
22nd JUNE 2017
WEEKLY PHARMA NEWSLETTER
Study co-author Katherine C.
Hughes, of the Harvard T.H.
Chan School of Public Health
in Boston, MA, and colleagues
recently reported their find-
ings in the journal Neurol-
ogy. Low-fat dairy is often
seen as a healthful alternative
to the full-fat kind. But ac-
cording to a new study, con-
suming higher amounts of low
-fat dairy may raise the risk of
Parkinson’s disease. Re-
searchers found that the risk
of Parkinson’s disease was
greater for adults who con-
sumed at least three servings
of low-fat dairy products every
day, compared with those who
consumed just one serving.
5 Free Online Drug Information Resources for a
Pharmacist's Toolbox:
“Low-fat dairy intake may raise
Parkinson’s risk”
PAKISTAN PHARMA CAREER DOOR
NEWSLETTER
5 Free Online Drug
Information Resources
1
L o w - f a t d a i r y i n -
t a k e m a y r a i s e
P a r k i n s o n ’ s r i s k
1
New Drug Approvals in
June 2017.
2
Illegal Drugs in Main-
stream Medicine?
3
Nasal Powder Fixed Severe
Low Blood Sugar
3
List OF FDA Approved
Drugs in 2016
4-7
List OF FDA Approved
Drugs in 2017.
8-10
Info about Pakistan
Pharma Career Door
11
Inside this issue:
SCIENTIFIC HEALTH
BENEFITS OF FASTING:
1. Fasting Promotes detoxifi-
cation
2. Fasting Rests Digestive
System
3. Fasting Resolves Inflam-
matory Response
4. Fasting Reduces Blood
Sugar
5. Fasting Increases Fat
breakdown
6. Fasting Corrects high
blood Pressure
7. Fasting Promotes Weight
loss
8. Fasting Promotes Healthy
diet
9. Fasting Boosts Immunity
10. Fasting May Help to
Overcome Addictions
*************
BY DR.JAVERIYA ANSARI ( PHARMACIST)
2. P A G E 2 P A K I S T A N P H A R M A C A R E E R D O O R
NEW DRUG APPROVALS IN JUNE 2017:
3. To evaluate the newly developed nasal gluca-
gon, researchers gave people with type 1 diabe-
tes a nasal device to use when they had a low
blood sugar episode.
Nasal glucagon is a dry powder that exists in a
small device. It looks something like a na-
sal steroid inhaler, but smaller. To use, a family
member or caregiver takes it out of the con-
tainer, puts it in the nose and pushes the bot-
tom of the canister... It's absorbed through the
nose into the bloodstream.
In the study, 69 people had 157 low blood sugar
TUESDAY, June 13, 2017
For many people with diabetes, low blood sugar
levels are a serious health risk, but researchers
report that a new nasal powder quickly reverses
the effects of this dangerous condition.
The nasal powder contains the hormone Glu-
cagon. This hormone tells the body to release
stored sugar, which will generally reverse
a lowblood sugar episode. Glucagon is currently
only available in an injectable form that has to
be mixed before it is injected.
episodes that were treated with nasal glucagon
In 96 percent of the episodes, blood sugar levels
returned to normal within 30 minutes, the
study found. Side effects were similar to in-
jectable glucagon, including nausea and vomit-
ing. The nasal powder also caused some nasal
irritation and headache. These side effects
tended to last an hour or less, the study found.
Findings from the study were to be pre-
sented soon at the American Diabetes
Association meeting in San Diego.
P A G E 3
ILLEGAL DRUGS IN MAINSTREAM MEDICINE??
Nasal Powder Fixed Severe Low Blood Sugar: ( Article Contributed By Nayab Zehra )
V O L U M E 2 , I S S U E 2
Over the last decade, the science community has started to use Psychedelic drugs, a psychoactive drug whose primary action is to
alter cognition and perception; well known psychedelics include LSD, psilocybin mushrooms, mescaline and DMT, while drugs
such as cannabis and MDMA are also sometimes considered psychedelics. And so these drugs that have been used for recreation
are now finding medicinal purposes .
READERS CONTRIBUTION
4. The following database contains a listing of drugs approved by the Food and Drug Administration (FDA) for sale in the
United States. Drug information typically includes the drug name, approval status, indication of use, and clinical trial re-
sults.
Cardiology/Vascular Diseases
Byvalson (nebivolol and valsartan); Allergan; For the treatment of hypertension, Approved June 2016
Yosprala (aspirin and omeprazole); Aralez Pharmaceuticals; For the prevention of cardiovascular and cerebrovascu-
lar events, Approved September 2016
Dermatology
Ameluz (aminolevulinic acid hydrochloride); Biofrontera Pharma;
For the treatment of actinic keratoses, Approved May 2016
Eucrisa• (crisaborole) ointment; Pfizer; For the treatment of atopic
dermatitis, Approved December 2016
Taltz (ixekizumab); Eli Lilly; For the treatment of plaque psoriasis, Ap-
proved March 2016
Endocrinology
Adlyxin (lixisenatide); Sanofi Aventis; For the treatment of type II diabe-
tes, Approved July 2016
Soliqua 100/33 (insulin glargine and lixisenatide injection); Sanofi
Aventis; For the treatment of inadequately controlled type II diabetes, Ap-
proved November 2016
Xultophy 100/3.6 (insulin degludec and liraglutide injection);
Novo Nordisk; For the treatment of inadequately controlled type II diabetes,
Approved November 2016
Family Medicine
Byvalson (nebivolol and valsartan); Allergan; For the treatment of hypertension, Approved June 2016
Onzetra Xsail (sumatriptan nasal powder) ; Avanir; For the treatment of migraine, Approved January 2016
Soliqua 100/33 (insulin glargine and lixisenatide injection); Sanofi Aventis; For the treatment of inadequately
controlled type II diabetes, Approved November 2016
Xultophy 100/3.6 (insulin degludec and liraglutide injection); Novo Nordisk; For the treatment of inadequately
controlled type II diabetes, Approved November 2016
Gastroenterology
Zinplava (bezlotoxumab); Merck; For the treatment of recurrent Clostridium difficile infection in patients receiving
antibacterial treatment, Approved October 2016
Genetic Disease
Spinraza (nusinersen); Biogen; For the treatment of spinal muscular atrophy, Approved December 2016
P A G E 4 P A K I S T A N P H A R M A C A R E E R D O O R
2016 FDA Approved Drugs:
5. Hematology
Afstyla (Antihemophilic Factor (Recombinant), Single Chain); CSL Behring; For the treatment of hemophillia A,
Approved May 2016
Idelvion (Coagulation Factor IX (Recombinant), Albumin Fusion Protein); CSL Behring; For the treatment of
hemophilia B, Approved March 2016
Kovaltry [Antihemophilic Factor (Recombinant)]; Bayer ; For the treatment of hemophillia A, Approved March
2016
Opdivo (nivolumab); Bristol-Myers Squibb; For the treatment of classical Hodgkin lymphoma, Approved May 2016
Venclexta (venetoclax); AbbVie; For the treatment of chronic lymphocytic leukemia with 17p deletion, Approved April
2016
Hepatology (Liver, Pancreatic, Gall Bladder)
Defitelio (defibrotide sodium); Jazz Pharmaceuticals; For the treatment of hepatic veno-occlusive disease with renal
or pulmonary dysfunction following HSCT, Approved March 2016
Ocaliva (obeticholic acid); Intercept Pharmaceuticals; For the treatment of primary biliary cholangitis, Approved May
2016
Vemlidy (tenofovir alafenamide); Gilead Sciences; For the treatment of chronic hepatitis B , Approved November
2016
Zepatier (elbasvir and grazoprevir); Merck; For the treatment of chronic HCV genotypes 1 or 4 , Approved January
2016
Immunology
Afstyla (Antihemophilic Factor (Recombinant), Single Chain); CSL Behring; For the treatment of hemophillia A,
Approved May 2016
Descovy (emtricitabine and tenofovir alafenamide); Gilead; For the treatment of HIV-1 infection, Approved April
2016
Epclusa (sofosbuvir and velpatasvir) ; Gilead Sciences; For the treatment of hepatitis C, Approved June 2016
Odefsey (emtricitabine, rilpivirine, and tenofovir alafenamide); Gilead Sciences; For the treatment of HIV-1 as
initial therapy, Approved March 2016
Taltz (ixekizumab); Eli Lilly; For the treatment of plaque psoriasis, Approved March 2016
Vaxchora (Cholera Vaccine, Live, Oral); PaxVax; For active immunization against Cholera, Approved June 2016
Infections and Infectious Diseases
Anthim (obiltoxaximab); Elusys Therapeutics; For the treatment of inhalational anthrax , Approved March 2016
Descovy (emtricitabine and tenofovir alafenamide); Gilead; For the treatment of HIV-1 infection, Approved April
2016
Epclusa (sofosbuvir and velpatasvir) ; Gilead Sciences; For the treatment of hepatitis C, Approved June 2016
Odefsey (emtricitabine, rilpivirine, and tenofovir alafenamide); Gilead Sciences; For the treatment of HIV-1 as
initial therapy, Approved March 2016
Syndros (dronabinol oral solution); Insys Therapeutics; For the treatment of anorexia associated with AIDS and nau-
sea and vomiting associated with cancer chemotherapy, Approved July 2016
Vaxchora (Cholera Vaccine, Live, Oral); PaxVax; For active immunization against Cholera, Approved June 2016
Vemlidy (tenofovir alafenamide); Gilead Sciences; For the treatment of chronic hepatitis B , Approved November
2016
Zepatier (elbasvir and grazoprevir); Merck; For the treatment of chronic HCV genotypes 1 or 4 , Approved Jan,2016
Zinplava (bezlotoxumab); Merck; For the treatment of recurrent Clostridium difficile infection in patients receiving
antibacterial treatment, Approved October 2016
P A G E 5 P A K I S T A N P H A R M A C A R E E R D O O R
2016 FDA Approved Drugs:
6. Musculoskeletal
Exondys 51 (eteplirsen); Sarepta Therapeutics; For the treatment of Duchenne muscular dystrophy with mutated DMD
gene amenable to exon 51 skipping, Approved September 2016
Spinraza (nusinersen); Biogen; For the treatment of spinal muscular atrophy, Approved December 2016
Zinbryta (daclizumab) ; Biogen; For the treatment of relapsing multiple sclerosis, Approved May 2016
Nephrology
Cabometyx (cabozantinib); Exelixis; For the treatment of advanced renal cell carcinoma, Approved April 2016
Lenvima (lenvatinib); Eisai; For the treatment of advanced renal cell carcinoma, Approved May 2016
Rayaldee (calcifediol) ; Opko Health; For the treatment of secondary hyperparathyroidism in adults with stage 3 or 4
chronic kidney disease, Approved June 2016
Neurology
Briviact (brivaracetam); UCB; For the treatment of partial onset seizures related to epilepsy, Approved February 2016
Carnexiv (carbamazepine); Lundbeck; replacement therapy when oral administration is not feasible, in adults with
seizures, Approved October 2016
Exondys 51 (eteplirsen); Sarepta Therapeutics; For the treatment of Duchenne muscular dystrophy with mutated DMD
gene amenable to exon 51 skipping, Approved September 2016
Nuplazid (pimavanserin); Acadia Pharmaceuticals; For the treatment of hallucinations and delusions associated with
Parkinson’s disease, Approved April 2016
Nuplazid (pimavanserin); Acadia Pharmaceuticals; For the treatment of hallucinations and delusions associated with
Parkinson’s disease psychosis, Approved May 2016
Onzetra Xsail (sumatriptan nasal powder) ; Avanir; For the treatment of migraine, Approved January 2016
Spinraza (nusinersen); Biogen; For the treatment of spinal muscular atrophy, Approved December 2016
Troxyca ER (oxycodone + naltrexone); Pfizer; For the management of severe pain, Approved August 2016
Zinbryta (daclizumab) ; Biogen; For the treatment of relapsing multiple sclerosis, Approved May 2016
Obstetrics/Gynecology (Women’s Health)
Intrarosa (prasterone vaginal inser• t); Endoceutics; For the treatment of moderate to severe dyspareunia, a symp-
tom of vulvar and vaginal atrophy, due to menopause, Approved November 2016
Rubraca (rucaparib); Clovis Oncology; For the treatment of advanced ovarian cancer in women with deleterious germ-
line or somatic BRCA mutation, Approved December 2016
Oncology
Cabometyx (cabozantinib); Exelixis; For the treatment of advanced renal cell carcinoma, Approved April 2016
Keytruda (pembrolizumab); Merck; For the treatment of head and neck squamous cell cancer , Approved August 2016
Lartruvo (olaratumab) ; Eli Lilly; For the treatment of soft tissue sarcoma, Approved October 2016
Lenvima (lenvatinib); Eisai; For the treatment of advanced renal cell carcinoma, Approved May 2016
Opdivo (nivolumab); Bristol-Myers Squibb; For the treatment of classical Hodgkin lymphoma, Approved May 2016
Opdivo (nivolumab); Bristol-Myers Squibb; For the treatment of recurrent or metastatic squamous cell carcinoma of
the head and neck, Approved November 2016
Rubraca (rucaparib); Clovis Oncology; For the treatment of advanced ovarian cancer in women with deleterious germ-
line or somatic BRCA mutation, Approved December 2016
Sustol (granisetron); Heron Therapeutics; For the prevention of chemotherapy-induced nausea and vomiting, Ap-
proved August 2016
Syndros (dronabinol oral solution); Insys Therapeutics; For the treatment of anorexia associated with AIDS and nau-
sea and vomiting associated with cancer chemotherapy, Approved July 2016
P A G E 6 P A K I S T A N P H A R M A C A R E E R D O O R
2016 FDA Approved Drugs:
7. Tecentriq (atezolizumab); Genentech; For the treatment of urothelial carcinoma and metastatic non-small cell lung
cancer, Approved May 2016
Venclexta (venetoclax); AbbVie; For the treatment of chronic lymphocytic leukemia with 17p deletion, Approved April
2016
Ophthalmology
Humira (adalimumab); Abbvie; For the treatment of uveitis, Approved July 2016
Xiidra (lifitegrast); Shire; For the treatment of dry eye disease, Approved
July 2016
Pediatrics/Neonatology
Exondys 51 (eteplirsen); Sarepta Therapeutics; For the treatment of
Duchenne muscular dystrophy with mutated DMD gene amenable to exon 51
skipping, Approved September 2016
Kovaltry [Antihemophilic Factor (Recombinant)]; Bayer ; For the
treatment of hemophillia A, Approved March 2016
Spinraza (nusinersen); Biogen; For the treatment of spinal muscular atro-
phy, Approved December 2016
Pharmacology/Toxicology
Sustol (granisetron); Heron Therapeutics; For the prevention of chemo-
therapy-induced nausea and vomiting, Approved August 2016
Psychiatry/Psychology
Nuplazid (pimavanserin); Acadia Pharmaceuticals; For the treatment of hallucinations and delusions associated with
Parkinson’s disease psychosis, Approved May 2016
Pulmonary/Respiratory Diseases
Bevespi Aerosphere (glycopyrrolate and formoterol fumarate); AstraZeneca; For the treatment of chronic ob-
structive pulmonary disease, Approved April 2016
Cinqair (reslizumab); Teva Pharmaceuticals; For the treatment of severe asthma, Approved March 2016
Tecentriq (atezolizumab); Genentech; For the treatment of urothelial carcinoma and metastatic non-small cell lung
cancer, Approved May 2016
Urology
Tecentriq (atezolizumab); Genentech; For the treatment of urothelial carcinoma and metastatic non-small cell lung
cancer, Approved May 2016
Vaccines
Vaxchora (Cholera Vaccine, Live, Oral); PaxVax; For active immunization against Cholera, Approved June 2016
P A G E 7 P A K I S T A N P H A R M A C A R E E R D O O R
2016 FDA Approved Drugs:
8. Dermatology
Bavencio (avelumab) ; EMD Serono/Pfizer; For the treatment of Merkel cell carcinoma , Approved March 2017
Dupixent (dupilumab); Regeneron Pharmaceuticals; For the treatment of atopic dermatitis, Approved March 2017
Rhofade (oxymetazoline hydrochloride); Allergan; For the treatment of facial erythema associated with rosacea,
Approved January 2017
Siliq (brodalumab); Valeant Pharmaceuticals; For the treatment of plaque psoriasis , Approved February 2017
Endocrinology
Parsabiv (etelcalcetide); Amgen; For the treatment of secondary hyperparathyroidism in adults with chronic kidney
disease on hemodialysis, Approved February 2017
Qtern (dapagliflozin and saxagliptin) ; AstraZeneca; For the treatment of inadequately controlled type II diabetes ,
Approved February 2017
Family Medicine
Qtern (dapagliflozin and saxagliptin) ; AstraZeneca; For the treatment
of inadequately controlled type II diabetes , Approved February 2017
Trulance (plecanatide); Synergy Pharmaceuticals; For the treatment of
adults with chronic idiopathic constipation, Approved January 2017
Gastroenterology
Symproic (naldemedine); Shionogi; For the treatment of opioid-induced constipation, Approved March 2017
Trulance (plecanatide); Synergy Pharmaceuticals; For the treatment of adults with chronic idiopathic constipation,
Approved January 2017
Xermelo (telotristat ethyl); Lexicon Pharmaceuticals; For the treatment of carcinoid syndrome diarrhea, Approved
February 2017
Genetic Disease
Brineura (cerliponase alfa); BioMarin; For the treatment of late infantile neuronal ceroid lipofuscinosis type 2 , Ap-
proved April 2017
Hematology
Rydapt (midostaurin); Novartis; For the treatment of FLT3 positive acute myeloid leukemia and mastocytosis , Ap-
proved April 2017
Immunology
Ocrevus (ocrelizumab); Genentech; For the treatment of multiple sclerosis, Approved March 2017
Zerviate (cetirizine ophthalmic solution 0.24%); NicOx; For the treatment of ocular itching associated with allergic
conjunctivitis, Approved May 2017
P A G E 8 P A K I S T A N P H A R M A C A R E E R D O O R
“Winning doesn’t always mean being first, winning
means you’re doing better than you’ve done before.”
- Bonnie Blair
2017 FDA Approved Drugs:
9. Musculoskeletal
Brineura (cerliponase alfa); BioMarin; For the treatment of late infantile neuronal ceroid lipofuscinosis type 2 , Ap-
proved April 2017
Emflaza (deflazacort); Marathon Pharmaceuticals; For the treatment of Duchenne muscular dystrophy, Approved Feb-
ruary 2017
Kevzara (sarilumab); Sanofi ; For the treatment of active rheumatoid arthritis, Approved May 2017
Ocrevus (ocrelizumab); Genentech; For the treatment of multiple sclerosis, Approved March 2017
Tymlos (abaloparatide) ; Radius Health; For the treatment of postmenopausal women with osteoporosis at high risk
for fracture, Approved April 2017
Nephrology
Parsabiv (etelcalcetide); Amgen; For the treatment of secondary hyperparathyroidism in adults with chronic kidney
disease on hemodialysis, Approved February 2017
Neurology
Austedo (deutetrabenazine) ; Teva Pharmaceuticals; For the treatment
of chorea associated with Huntington’s disease, Approved April 2017
Brineura (cerliponase alfa); BioMarin; For the treatment of late infan-
tile neuronal ceroid lipofuscinosis type 2 , Approved April 2017
Ingrezza (valbenazine); Neurocrine Biosciences; For the treatment of
tardive dyskinesia, Approved April 2017
Radicava (edaravone); Mitsubishi Tanabe Pharma; For the treatment of
amyotrophic lateral sclerosis , Approved May 2017
Xadago (safinamide); Newron Pharmaceuticals; For the treatment of Parkinson's disease, Approved March 2017
Obstetrics/Gynecology (Women’s Health)
Kisqali (ribociclib); Novartis; For the treatment of breast cancer, Approved March 2017
Tymlos (abaloparatide) ; Radius Health; For the treatment of postmenopausal women with osteoporosis at high risk
for fracture, Approved April 2017
Zejula (niraparib); Tesaro; For the treatment of recurrent epithelial ovarian, fallopian tube, or primary peritoneal can-
cer , Approved March 2017
Oncology
Alunbrig (brigatinib); Ariad Pharmaceuticals; For the treatment of advanced ALK-positive metastatic non-small cell
lung cancer, Approved April 2017
Bavencio (avelumab) ; EMD Serono/Pfizer; For the treatment of Merkel cell carcinoma , Approved March 2017
Imfinzi (durvalumab); AstraZeneca; For the treatment of advanced or metastatic urothelial carcinoma, Approved May
2017
Kisqali (ribociclib); Novartis; For the treatment of breast cancer, Approved March 2017
Rydapt (midostaurin); Novartis; For the treatment of FLT3 positive acute myeloid leukemia and mastocytosis , Ap-
proved April 2017
Xermelo (telotristat ethyl); Lexicon Pharmaceuticals; For the treatment of carcinoid syndrome diarrhea, Approved
February 2017
Zejula (niraparib); Tesaro; For the treatment of recurrent epithelial ovarian, fallopian tube, or primary peritoneal can-
cer , Approved March 2017
P A G E 9 P A K I S T A N P H A R M A C A R E E R D O O R
“Hardships often prepare ordinary people
for an extraordinary destiny”
-C.S.LEWIS
2017 FDA Approved Drugs:
10. Ophthalmology
Zerviate (cetirizine ophthalmic solution 0.24%); NicOx; For the treatment of ocular itching associated with allergic
conjunctivitis, Approved May 2017
Pediatrics/Neonatology
Brineura (cerliponase alfa); BioMarin; For the treatment of late infantile neuronal ceroid lipofuscinosis type 2 , Ap-
proved April 2017
Emflaza (deflazacort); Marathon Pharmaceuticals; For the treatment of Duchenne muscular dystrophy, Approved Feb-
ruary 2017
Rheumatology
Kevzara (sarilumab); Sanofi ; For the treatment of active rheumatoid arthritis, Approved May 2017
Urology
Imfinzi (durvalumab); AstraZeneca; For the treatment of advanced or metastatic urothelial carcinoma, Approved May
2017
P A G E 1 0 P A K I S T A N P H A R M A C A R E E R D O O R
2017 FDA Approved Drugs:
It is found that “Guanabana”or Tree sour soup,
a magical fruit with ant carcinogenic properties .”
11. Pakistan Pharma Career Door is a Facebook Social Group
created by Javeriya Ansari (Pharmacsit) on 1st November,
2014 with an aim to provide;
* Latest information about the ongoing Pharma Research.
*Information about new discoveries and inventions in the
field of Science.
*Links to Download Pharma related Books and Notes .
* Link to apply for the Job opportunities in Pharmaceuti-
cal Industries .
*Any query regarding the pharma jobs / pharma subject
will be answered on group and email.
For your contribution and suggestions kindly email on:
Javeriya.pharmacist@gmail.com
USEFUL INFORMATION:
LINKTO BLOG:
http://pakpharmacareerdoor.blogspot.com/
WEBLINK:
https://www.facebook.com/groups/
PakPharmacareerdoor/
PAKISTAN PHARMA
CAREER DOOR