PAHO is the oldest international health agency in the world, founded in 1902. It works with all countries in the Americas to improve health and quality of life. Over its 113 year history, PAHO has helped achieve major improvements like increasing life expectancy by 45 years and eradicating diseases like smallpox. However, it still faces critical challenges like noncommunicable diseases, health inequities, and ensuring universal health coverage and access to care.