Iago manipulates Othello into believing that his wife Desdemona has been unfaithful with Cassio through lies and deceit involving a handkerchief. Othello, enraged by Iago's tricks, smothers Desdemona to death, only realizing too late that she had been faithful. Iago's scheming is ultimately exposed, leading to arrests, but not before more blood is shed as Iago kills his wife Emilia and Othello commits suicide over his misdeeds.