Open Drug Discovery Teams @ Hacking Health Montreal
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Alex Clark of Molecular Materials Informatics (http://molmatinf.com) presents the Open Drug Discovery Teams project to the Hacking Health Montreal audience, April 2013.
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Open Drug Discovery Teams @ Hacking Health Montreal
- 1. !1 Open Drug Discovery Teams Dr. Alex M. Clark Dr. Sean Ekins © 2012-2013 Molecular Materials Informatics, Inc. and Collaborations in Chemistry April 2013 Hacking Health Montréal http://molmatinf.com/oddt.html
- 2. Background
- 3. Motivation • Early 2012: Sean Ekins met Jill Wood at a rare disease conference • Mother of a child suffering from Sanfillipo Syndrome - Incident rate: 1 in 100,000 • Had to become a scientist, doctor, entrepreneur and venture capitalist to accelerate a cure • Finding information shouldn't be so hard... Jonah's Just Begun Phoenix Nest Biotech phoenixnestbiotech.com
- 4. The Problem • Rare diseases? Neglected markets? • Resources are extremely tight • Cannot afford not to share research # $ • Drug discovery research is very asymmetric • Diseases with many wealthy sufferers get most of the attention: great return on investment >7000 rare diseases
- 5. The Solution • government • pharma • charity funding • academics • startups • foundations • literature • open science • blogs publication Twitter • content aggregation • research communities Open Drug Discovery Teams #hashtags RSS Feeds
- 6. The App: Open Drug Discovery Teams #sanfilipposyndrome #tuberculosis #leishmaniasis #huntingtons#hivaids #chagas#malaria #greenchemistry #H5N1 • iPhone, iPod, iPad • Free! http://oddt.net
- 7. Topic Browsing • Users curate the relevant content by endorsing • Interaction is done by tweeting from the app • The result is a crowd-curated knowledge resource • Magazine-like • Thumbnails • Links • Molecules • Voting
- 8. Molecules • ODDT is chemistry aware... • ... harvesting chemical data allows many possibilities
- 9. Where to next • ODDT is an experimental project • Sponsorship: • App is free, data is totally open • Potentially valuable intellectual property • Know of a rare or neglected disease with an online community? ➡ We can add a new topic • Know anyone who is interested in sponsoring projects to increase awareness of rare or neglected diseases? ➡ Contact us!
- 10. !10 More Information Dr. Alex M. Clark @aclarkxyz Dr. Sean Ekins @collabchem © 2012-2013 Molecular Materials Informatics, Inc. and Collaborations in Chemistry http://oddt.net http://molmatinf.com/oddt.html http://cheminf20.org http://collabchem.com