The document discusses strategies for effectively recruiting and retaining clinical trial participants based on focus group research. It identifies participants' key information needs, concerns, and motivations and barriers to participation. Addressing potential side effects, providing user-friendly study information for families, and maintaining ongoing communication are important. Participants want expenses covered and expect updates, resources, and a supportive community experience. Barriers include distance, inflexible hours, and burdensome visits. Tailoring the experience to individual needs and building rapport with empathetic staff is critical to recruitment and retention.