The document outlines various Natriance extracts by Ashland, highlighting their benefits for skin care, including brightening, anti-aging, hydration, sun defense, and surface renewal. Each extract is supported by bioefficacy tests and suggested applications across different skin types. Natriance products offer clinically proven results while emphasizing simplicity and natural ingredients.

1. With good chemistry great things happen.™
Natriance™ extracts
Simply Essential, Inspired by Nature™
Body Care and Face Care
Simply essential, inspired by Nature™

2. Natriance Brightener Extract
To brighten and illuminate the skin
End Benefit
Natriance Brightener extract helps skin reveal its own
radiance, create a natural glow and sublimate skin tone for a
brighter and more luminous appearance.
Bioefficacy Tests
• Ex vivo test – melanin staining
Melanin staining quantification suggests better efficacy
with Natriance Brightener extract at 1% than results
obtained with benchmark products.
• Clinical efficacy (21 volunteers)
Decrease of melanin index and increase of Luminance (L*)
in 28 days
Applications
• Body and face care
• Hand care
• Anti-aging creams
• Brightening/whitening formulations
• Day and night formulations
Skin Types
For all types of skin that need to brighten, be more radiant
and more luminous
INCI Name
Water (Aqua) (and) Glycerin (and) HydrolyzedYeast Protein
Use Level
1% to 3% (0.3% recommended use level for USA1
)
1) Efficacy above kojic acid at 1% is considered as whitening activity in the USA and therefore
falling under the requirement of an OTC drug (kojic acid CIR). See recommended use level for
cosmetic application in the USA (21CFR310). Natriance Brightener extract at 0.3% demonstrates
efficacy below kojic acid at 1% (Fontana-Masson results on ex vivo skin not shown here).
Natriance Wrinkle-less Extract
To erase signs of time and keep wrinkles away
End Benefit
Natriance Wrinkle-less extract helps skin reduce one of the
most visible signs of aging – wrinkles. Skin may appear
smoother, refreshed and firmer.
Bioefficacy Tests
• Ex vivo test – collagen
Maintenance of collagen after UV stress
• Clinical efficacy (8 volunteers)
Appearance of wrinkles improved (number of wrinkles,
length, depth, average length)
Applications
• Body and face care
• Day and night creams
• Anti-aging products
• For men and women
Skin Types
From young skin with first expression lines to mature skin
with deeper wrinkles
INCI Name
Water (Aqua) (and) Glycerin (and) Hydrolyzed Corn Protein
Use Level
1% to 2%
Essential and Clinically Proven Ingredients for Body Care and Face Care
In a market dominated by complex skin care solutions, Ashland Specialty Ingredients provides the first
line of natural, simple ingredients offering clinically proven skin benefits to address essential consumer
needs. Natriance extracts provide gentle bioefficacy respecting the genuine nature of the skin. Easy to
understand and easy to use, this line of ingredients, which is inspired by nature, is simply essential for
truly efficacious body care and face care formulations.
“Nature is simply beautiful and
Natriance extracts bring it to your skin.”

3. Natriance Self-hydrate Extract
To teach skin self-moisturization
End Benefit
Natriance Self-hydrate extract helps educate skin to draw
water from the inside. By enhancing essential water
molecules, hydrasources are restored resulting in skin that is
visibly more quenched.
Bioefficacy Tests
• Ex vivo test – hyaluronic acid and other GAGs
Enhancement of GAGs staining
• Clinical efficacy (12 volunteers)
Skin moisture increased after 8 days
Applications
• Body and face care
• Day and night creams
• Moisturizing products
• For men and women
Skin Types
For all types of thirsty and dry skin that need to be
naturally hydrated
INCI Name
Water (Aqua) (and) Propanediol (and) Pea (Pisum sativum)
Extract
Use Level
1% to 2%
Natriance Solar Defense Extract
To adapt skin to preserve sun defense
capital and beauty
End Benefit
Natriance Solar Defense extract helps preserve the skin’s
innate self-defense against solar radiations. It helps skin
be better adapted to solar aggressions and limit damage
preserving skin’s healthy appearance and beauty.
Bioefficacy Tests
• In vitro test – SOD
Limit SOD decrease when skin is affected by UV
• Ex vivo test – sunburn cells
Fewer sunburn cells after UV stress
• Clinical efficacy (12 volunteers)
Water loss (TEWL) induced by solar stress is limited
Applications
• Body and face care
• Day and protective products
• Sun care products
• Formulations against premature aging
and photo-aging
Skin Types
For all types of skin that need to improve the natural
self-defenses against the sun’s agressions
INCI Name
Water (Aqua) (and) Propanediol (and) Hydrolyzed Soy Protein
Use Level
1% to 2%
Natriance Renovate Extract
To help skin gently transform its
surface and reduce flaws
End Benefit
Natriance Renovate extract helps skin renovate its surface
and transform the texture into a visibly renewed skin with
less squames and flaws. With a gentle, natural renewal from
the inside, the skin surface is re-texturized.
Bioefficacy Tests
• Ex vivo test – filaggrin
Enhancement of filaggrin staining
• Clinical efficacy (8 volunteers)
Fewer squames and flaws quantified by D’Squames
analyzer after 10 days
Applications
• Body and face care
• Flawless effect creams
• Skin perfecter products
• For men and women
Skin Types
For all types of skin that need to improve skin surface quality,
reduce squames and attenuate flaws
INCI Name
Water (Aqua) (and) Glycerin (and) Hydrolyzed Linseed Extract
Use Level
2%

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© 2012,Ashland
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All statements, information and data presented herein are
believed to be accurate and reliable, but are not to be taken
as a guarantee, an express warranty, or an implied warranty
of merchantability or fitness for a particular purpose, or
representation, express or implied, for which Ashland Inc.
and its subsidiaries assume legal responsibility.
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