Personal protective equipment (PPE) is critical for protecting healthcare workers and containing the spread of COVID-19. PPE includes coveralls, face shields, gloves, goggles, headcovers, masks, and footwear. It is important to properly don and doff PPE to prevent exposure to contaminated environments. Key steps for using PPE safely include sanitizing hands, properly securing all pieces of the equipment, and carefully removing items one by one without touching the outer surfaces to avoid spreading germs. PPE plays a vital role in preventing the transmission of the highly contagious COVID-19 virus from infected individuals.