She is someone that the author really admires. The author holds this person in high regard and looks up to them. Whoever "she" is, the author respects and appreciates her greatly.
I recently took a trip to Syria. While there, I visited several major cities including Damascus, Aleppo, and Homs. The ancient architecture and cultural sites I saw provided insight into Syria's rich history.
This short document discusses a book called "H.I.V.E Rouge" by Mark Walden. It includes a picture that represents the book and the author's thoughts on what a picture representing the book might look like.
1. The document is a test for English proficiency that contains two parts - speaking and writing ability.
2. The speaking section contains 10 questions testing conversational skills through dialogue choices.
3. The writing section contains 20 questions testing appropriate word and phrase choices to complete sentences.
She is someone that the author really admires. The author holds this person in high regard and looks up to them. Whoever "she" is, the author respects and appreciates her greatly.
The document expresses admiration for an unnamed person. In just a few words, it conveys positive feelings toward someone without providing details about who that person is or why they are admired. Overall the short statement communicates high regard for an individual.
I recently took a trip to Syria. While there, I visited several major cities including Damascus, Aleppo, and Homs. The ancient architecture and cultural sites I saw provided insight into Syria's rich history.
This short document discusses a book called "H.I.V.E Rouge" by Mark Walden. It includes a picture that represents the book and the author's thoughts on what a picture representing the book might look like.
1. The document is a test for English proficiency that contains two parts - speaking and writing ability.
2. The speaking section contains 10 questions testing conversational skills through dialogue choices.
3. The writing section contains 20 questions testing appropriate word and phrase choices to complete sentences.
She is someone that the author really admires. The author holds this person in high regard and looks up to them. Whoever "she" is, the author respects and appreciates her greatly.
The document expresses admiration for an unnamed person. In just a few words, it conveys positive feelings toward someone without providing details about who that person is or why they are admired. Overall the short statement communicates high regard for an individual.
This document provides information about One Minute News (OMN), a digital media company that produces short-form video news segments targeted at millennials. OMN was founded by Doug Greenlaw to be an alternative news source designed and created by millennials for millennials. OMN produces 60-second video segments covering trending news, entertainment, sports and other topics of interest to 18-34 year olds. These videos are distributed through OMN's global partners and platforms like YouTube to reach over 40 million young viewers each month. The document outlines OMN's content, talent, advertising opportunities and ability to help brands engage millennials through video sponsorships and custom content.
This document provides a summary of the village and house of Doctor Dolittle. Doctor Dolittle is a doctor who treats animals and lives in the village of Puddleby-on-the-Marsh with his sister and many animals. His house is usually chaotic due to all the animals living there. Doctor Dolittle goes on a trip to Africa with his animals but their ship sinks and they must swim to shore.
1) Temozolomide is an alkylating agent recommended for the adjuvant treatment of glioblastoma multiforme (GBM) along with radiation therapy.
2) A phase III trial showed that patients with GBM who received temozolomide concomitantly with radiation therapy and as maintenance therapy had improved progression-free survival and overall survival compared to radiation therapy alone.
3) The mechanism of action of temozolomide involves its metabolic activation to the reactive compound MTIC, which methylates guanine residues in DNA and inhibits DNA, RNA, and protein synthesis. However, increased activity of DNA repair enzymes such as O6-methylguanine DNA methyltransferase can lead to
This document discusses hypoxia and its effects in radiotherapy. It defines oxygen effect as the increased radiosensitivity seen in aerated tissues compared to hypoxic tissues. The mechanism is that oxygen helps fix radiation-induced DNA damage, making it irreparable. Fractionated radiotherapy can overcome hypoxia through reoxygenation of tumor cells between fractions. Strategies to overcome hypoxia include hyperbaric oxygen, chemical radiosensitizers, hypoxic cytotoxins, and boosting tumor oxygenation.
This document discusses the treatment of low-grade gliomas. It notes that maximal surgical resection is generally recommended when feasible and associated with more favorable outcomes. For pilocytic astrocytomas, no adjuvant therapy is necessary after complete resection. Postoperative radiotherapy may be considered for incompletely resected or higher risk nonpilocytic gliomas. Recent trials found no survival advantage from higher radiation doses compared to 45-54 Gy or from early radiotherapy versus delayed radiotherapy. Temozolomide is being tested in clinical trials for nonpilocytic gliomas.
The document discusses the role of chemotherapy in carcinoma of the stomach. It outlines several key trials investigating neoadjuvant, adjuvant and perioperative chemotherapy approaches. The MAGIC trial showed significantly improved 5-year survival with perioperative chemotherapy compared to surgery alone. The French FNCLCC trial also demonstrated improved disease-free and overall survival with perioperative chemotherapy. Adjuvant chemoradiation was shown in the INT0116/SWOG 9008 trial to improve 5-year overall and disease-free survival compared to surgery alone. The Japanese S-1 trial found significant benefit in 5-year disease-free and overall survival with adjuvant S-1 chemotherapy compared to observation after surgery.
This document discusses the management of neck nodes in head and neck cancer. It covers lymph node levels, risk factors for metastasis, diagnostic workup, staging, surgical and radiation treatment options. For clinically negative nodes, elective neck irradiation or dissection are equally effective at controlling subclinical disease. For clinically positive nodes, factors like number of positive nodes and size influence treatment planning. Combined modality treatment with surgery and radiation provides better control than either alone for more advanced neck disease.
This document summarizes the results of two randomized controlled trials (PORTEC-1 and PORTEC-2) that compared pelvic external beam radiotherapy (EBRT) to vaginal brachytherapy (VBT) or no additional treatment (NAT) for patients with endometrial carcinoma. PORTEC-1 showed that EBRT improves local control over NAT but does not provide a survival benefit and is associated with long-term side effects. PORTEC-2 found that VBT achieves similar local control as EBRT with fewer side effects, establishing VBT as the preferred adjuvant treatment for high intermediate risk patients.
This document discusses DNA damage and repair mechanisms in response to radiotherapy. It describes how ionizing radiation can cause DNA single and double strand breaks through energy deposition events. The two main pathways for repairing double strand breaks are nonhomologous end joining, which is error-prone and occurs in G1 phase, and homologous recombination repair, which is error-free and occurs in late S and G2 phases. Defects in various DNA repair pathways can result in increased radiosensitivity or cancer predisposition. Chromosomal aberrations seen in lymphocytes after radiation exposure can also be used as biomarkers to estimate radiation dose.
This document discusses the management of endometrial carcinoma. It covers diagnosis through clinical examinations and investigations. Surgical staging is now standard practice to better guide adjuvant therapy. Prognostic factors include stage, grade, depth of invasion and nodal involvement. Treatment involves surgery, with radiation therapy and chemotherapy used for more advanced or high risk cases. Ongoing follow up is also recommended.
Hormone therapy is recommended for women with hormone receptor-positive, non-metastatic breast cancer. Ideal candidates include those who are post-menopausal or have undergone bilateral oophorectomy. Treatment options include tamoxifen, aromatase inhibitors like letrozole or anastrozole, and ovarian suppression with gonadotropin-releasing hormone agonists. While aromatase inhibitors are preferred for post-menopausal women, pre-menopausal high-risk women should receive ovarian suppression plus an aromatase inhibitor. Hormone therapy should be administered for 5 years or longer to reduce the risk of breast cancer recurrence and mortality.
Nasopharyngeal carcinoma is typically treated with radiation therapy. Concurrent chemotherapy and radiation is the standard for locally advanced disease and improves survival compared to radiation alone. Intensity-modulated radiation therapy provides better tumor coverage and reduces side effects. Surgery has a limited role except for biopsy or salvaging recurrent tumors. Temporal lobe necrosis is a serious potential complication, so fractional doses above 2Gy should be avoided. Close follow-up is needed due to risk of recurrence or late effects.
How to Manage Your Lost Opportunities in Odoo 17 CRMCeline George
Odoo 17 CRM allows us to track why we lose sales opportunities with "Lost Reasons." This helps analyze our sales process and identify areas for improvement. Here's how to configure lost reasons in Odoo 17 CRM
Walmart Business+ and Spark Good for Nonprofits.pdfTechSoup
"Learn about all the ways Walmart supports nonprofit organizations.
You will hear from Liz Willett, the Head of Nonprofits, and hear about what Walmart is doing to help nonprofits, including Walmart Business and Spark Good. Walmart Business+ is a new offer for nonprofits that offers discounts and also streamlines nonprofits order and expense tracking, saving time and money.
The webinar may also give some examples on how nonprofits can best leverage Walmart Business+.
The event will cover the following::
Walmart Business + (https://business.walmart.com/plus) is a new shopping experience for nonprofits, schools, and local business customers that connects an exclusive online shopping experience to stores. Benefits include free delivery and shipping, a 'Spend Analytics” feature, special discounts, deals and tax-exempt shopping.
Special TechSoup offer for a free 180 days membership, and up to $150 in discounts on eligible orders.
Spark Good (walmart.com/sparkgood) is a charitable platform that enables nonprofits to receive donations directly from customers and associates.
Answers about how you can do more with Walmart!"
How to Add Chatter in the odoo 17 ERP ModuleCeline George
In Odoo, the chatter is like a chat tool that helps you work together on records. You can leave notes and track things, making it easier to talk with your team and partners. Inside chatter, all communication history, activity, and changes will be displayed.
A review of the growth of the Israel Genealogy Research Association Database Collection for the last 12 months. Our collection is now passed the 3 million mark and still growing. See which archives have contributed the most. See the different types of records we have, and which years have had records added. You can also see what we have for the future.
How to Make a Field Mandatory in Odoo 17Celine George
In Odoo, making a field required can be done through both Python code and XML views. When you set the required attribute to True in Python code, it makes the field required across all views where it's used. Conversely, when you set the required attribute in XML views, it makes the field required only in the context of that particular view.
Main Java[All of the Base Concepts}.docxadhitya5119
This is part 1 of my Java Learning Journey. This Contains Custom methods, classes, constructors, packages, multithreading , try- catch block, finally block and more.
The simplified electron and muon model, Oscillating Spacetime: The Foundation...RitikBhardwaj56
Discover the Simplified Electron and Muon Model: A New Wave-Based Approach to Understanding Particles delves into a groundbreaking theory that presents electrons and muons as rotating soliton waves within oscillating spacetime. Geared towards students, researchers, and science buffs, this book breaks down complex ideas into simple explanations. It covers topics such as electron waves, temporal dynamics, and the implications of this model on particle physics. With clear illustrations and easy-to-follow explanations, readers will gain a new outlook on the universe's fundamental nature.
This document provides information about One Minute News (OMN), a digital media company that produces short-form video news segments targeted at millennials. OMN was founded by Doug Greenlaw to be an alternative news source designed and created by millennials for millennials. OMN produces 60-second video segments covering trending news, entertainment, sports and other topics of interest to 18-34 year olds. These videos are distributed through OMN's global partners and platforms like YouTube to reach over 40 million young viewers each month. The document outlines OMN's content, talent, advertising opportunities and ability to help brands engage millennials through video sponsorships and custom content.
This document provides a summary of the village and house of Doctor Dolittle. Doctor Dolittle is a doctor who treats animals and lives in the village of Puddleby-on-the-Marsh with his sister and many animals. His house is usually chaotic due to all the animals living there. Doctor Dolittle goes on a trip to Africa with his animals but their ship sinks and they must swim to shore.
1) Temozolomide is an alkylating agent recommended for the adjuvant treatment of glioblastoma multiforme (GBM) along with radiation therapy.
2) A phase III trial showed that patients with GBM who received temozolomide concomitantly with radiation therapy and as maintenance therapy had improved progression-free survival and overall survival compared to radiation therapy alone.
3) The mechanism of action of temozolomide involves its metabolic activation to the reactive compound MTIC, which methylates guanine residues in DNA and inhibits DNA, RNA, and protein synthesis. However, increased activity of DNA repair enzymes such as O6-methylguanine DNA methyltransferase can lead to
This document discusses hypoxia and its effects in radiotherapy. It defines oxygen effect as the increased radiosensitivity seen in aerated tissues compared to hypoxic tissues. The mechanism is that oxygen helps fix radiation-induced DNA damage, making it irreparable. Fractionated radiotherapy can overcome hypoxia through reoxygenation of tumor cells between fractions. Strategies to overcome hypoxia include hyperbaric oxygen, chemical radiosensitizers, hypoxic cytotoxins, and boosting tumor oxygenation.
This document discusses the treatment of low-grade gliomas. It notes that maximal surgical resection is generally recommended when feasible and associated with more favorable outcomes. For pilocytic astrocytomas, no adjuvant therapy is necessary after complete resection. Postoperative radiotherapy may be considered for incompletely resected or higher risk nonpilocytic gliomas. Recent trials found no survival advantage from higher radiation doses compared to 45-54 Gy or from early radiotherapy versus delayed radiotherapy. Temozolomide is being tested in clinical trials for nonpilocytic gliomas.
The document discusses the role of chemotherapy in carcinoma of the stomach. It outlines several key trials investigating neoadjuvant, adjuvant and perioperative chemotherapy approaches. The MAGIC trial showed significantly improved 5-year survival with perioperative chemotherapy compared to surgery alone. The French FNCLCC trial also demonstrated improved disease-free and overall survival with perioperative chemotherapy. Adjuvant chemoradiation was shown in the INT0116/SWOG 9008 trial to improve 5-year overall and disease-free survival compared to surgery alone. The Japanese S-1 trial found significant benefit in 5-year disease-free and overall survival with adjuvant S-1 chemotherapy compared to observation after surgery.
This document discusses the management of neck nodes in head and neck cancer. It covers lymph node levels, risk factors for metastasis, diagnostic workup, staging, surgical and radiation treatment options. For clinically negative nodes, elective neck irradiation or dissection are equally effective at controlling subclinical disease. For clinically positive nodes, factors like number of positive nodes and size influence treatment planning. Combined modality treatment with surgery and radiation provides better control than either alone for more advanced neck disease.
This document summarizes the results of two randomized controlled trials (PORTEC-1 and PORTEC-2) that compared pelvic external beam radiotherapy (EBRT) to vaginal brachytherapy (VBT) or no additional treatment (NAT) for patients with endometrial carcinoma. PORTEC-1 showed that EBRT improves local control over NAT but does not provide a survival benefit and is associated with long-term side effects. PORTEC-2 found that VBT achieves similar local control as EBRT with fewer side effects, establishing VBT as the preferred adjuvant treatment for high intermediate risk patients.
This document discusses DNA damage and repair mechanisms in response to radiotherapy. It describes how ionizing radiation can cause DNA single and double strand breaks through energy deposition events. The two main pathways for repairing double strand breaks are nonhomologous end joining, which is error-prone and occurs in G1 phase, and homologous recombination repair, which is error-free and occurs in late S and G2 phases. Defects in various DNA repair pathways can result in increased radiosensitivity or cancer predisposition. Chromosomal aberrations seen in lymphocytes after radiation exposure can also be used as biomarkers to estimate radiation dose.
This document discusses the management of endometrial carcinoma. It covers diagnosis through clinical examinations and investigations. Surgical staging is now standard practice to better guide adjuvant therapy. Prognostic factors include stage, grade, depth of invasion and nodal involvement. Treatment involves surgery, with radiation therapy and chemotherapy used for more advanced or high risk cases. Ongoing follow up is also recommended.
Hormone therapy is recommended for women with hormone receptor-positive, non-metastatic breast cancer. Ideal candidates include those who are post-menopausal or have undergone bilateral oophorectomy. Treatment options include tamoxifen, aromatase inhibitors like letrozole or anastrozole, and ovarian suppression with gonadotropin-releasing hormone agonists. While aromatase inhibitors are preferred for post-menopausal women, pre-menopausal high-risk women should receive ovarian suppression plus an aromatase inhibitor. Hormone therapy should be administered for 5 years or longer to reduce the risk of breast cancer recurrence and mortality.
Nasopharyngeal carcinoma is typically treated with radiation therapy. Concurrent chemotherapy and radiation is the standard for locally advanced disease and improves survival compared to radiation alone. Intensity-modulated radiation therapy provides better tumor coverage and reduces side effects. Surgery has a limited role except for biopsy or salvaging recurrent tumors. Temporal lobe necrosis is a serious potential complication, so fractional doses above 2Gy should be avoided. Close follow-up is needed due to risk of recurrence or late effects.
How to Manage Your Lost Opportunities in Odoo 17 CRMCeline George
Odoo 17 CRM allows us to track why we lose sales opportunities with "Lost Reasons." This helps analyze our sales process and identify areas for improvement. Here's how to configure lost reasons in Odoo 17 CRM
Walmart Business+ and Spark Good for Nonprofits.pdfTechSoup
"Learn about all the ways Walmart supports nonprofit organizations.
You will hear from Liz Willett, the Head of Nonprofits, and hear about what Walmart is doing to help nonprofits, including Walmart Business and Spark Good. Walmart Business+ is a new offer for nonprofits that offers discounts and also streamlines nonprofits order and expense tracking, saving time and money.
The webinar may also give some examples on how nonprofits can best leverage Walmart Business+.
The event will cover the following::
Walmart Business + (https://business.walmart.com/plus) is a new shopping experience for nonprofits, schools, and local business customers that connects an exclusive online shopping experience to stores. Benefits include free delivery and shipping, a 'Spend Analytics” feature, special discounts, deals and tax-exempt shopping.
Special TechSoup offer for a free 180 days membership, and up to $150 in discounts on eligible orders.
Spark Good (walmart.com/sparkgood) is a charitable platform that enables nonprofits to receive donations directly from customers and associates.
Answers about how you can do more with Walmart!"
How to Add Chatter in the odoo 17 ERP ModuleCeline George
In Odoo, the chatter is like a chat tool that helps you work together on records. You can leave notes and track things, making it easier to talk with your team and partners. Inside chatter, all communication history, activity, and changes will be displayed.
A review of the growth of the Israel Genealogy Research Association Database Collection for the last 12 months. Our collection is now passed the 3 million mark and still growing. See which archives have contributed the most. See the different types of records we have, and which years have had records added. You can also see what we have for the future.
How to Make a Field Mandatory in Odoo 17Celine George
In Odoo, making a field required can be done through both Python code and XML views. When you set the required attribute to True in Python code, it makes the field required across all views where it's used. Conversely, when you set the required attribute in XML views, it makes the field required only in the context of that particular view.
Main Java[All of the Base Concepts}.docxadhitya5119
This is part 1 of my Java Learning Journey. This Contains Custom methods, classes, constructors, packages, multithreading , try- catch block, finally block and more.
The simplified electron and muon model, Oscillating Spacetime: The Foundation...RitikBhardwaj56
Discover the Simplified Electron and Muon Model: A New Wave-Based Approach to Understanding Particles delves into a groundbreaking theory that presents electrons and muons as rotating soliton waves within oscillating spacetime. Geared towards students, researchers, and science buffs, this book breaks down complex ideas into simple explanations. It covers topics such as electron waves, temporal dynamics, and the implications of this model on particle physics. With clear illustrations and easy-to-follow explanations, readers will gain a new outlook on the universe's fundamental nature.
How to Build a Module in Odoo 17 Using the Scaffold MethodCeline George
Odoo provides an option for creating a module by using a single line command. By using this command the user can make a whole structure of a module. It is very easy for a beginner to make a module. There is no need to make each file manually. This slide will show how to create a module using the scaffold method.
How to Fix the Import Error in the Odoo 17Celine George
An import error occurs when a program fails to import a module or library, disrupting its execution. In languages like Python, this issue arises when the specified module cannot be found or accessed, hindering the program's functionality. Resolving import errors is crucial for maintaining smooth software operation and uninterrupted development processes.
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ISO/IEC 27001, ISO/IEC 42001, and GDPR: Best Practices for Implementation and...PECB
Denis is a dynamic and results-driven Chief Information Officer (CIO) with a distinguished career spanning information systems analysis and technical project management. With a proven track record of spearheading the design and delivery of cutting-edge Information Management solutions, he has consistently elevated business operations, streamlined reporting functions, and maximized process efficiency.
Certified as an ISO/IEC 27001: Information Security Management Systems (ISMS) Lead Implementer, Data Protection Officer, and Cyber Risks Analyst, Denis brings a heightened focus on data security, privacy, and cyber resilience to every endeavor.
His expertise extends across a diverse spectrum of reporting, database, and web development applications, underpinned by an exceptional grasp of data storage and virtualization technologies. His proficiency in application testing, database administration, and data cleansing ensures seamless execution of complex projects.
What sets Denis apart is his comprehensive understanding of Business and Systems Analysis technologies, honed through involvement in all phases of the Software Development Lifecycle (SDLC). From meticulous requirements gathering to precise analysis, innovative design, rigorous development, thorough testing, and successful implementation, he has consistently delivered exceptional results.
Throughout his career, he has taken on multifaceted roles, from leading technical project management teams to owning solutions that drive operational excellence. His conscientious and proactive approach is unwavering, whether he is working independently or collaboratively within a team. His ability to connect with colleagues on a personal level underscores his commitment to fostering a harmonious and productive workplace environment.
Date: May 29, 2024
Tags: Information Security, ISO/IEC 27001, ISO/IEC 42001, Artificial Intelligence, GDPR
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This presentation includes basic of PCOS their pathology and treatment and also Ayurveda correlation of PCOS and Ayurvedic line of treatment mentioned in classics.