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Aws SaadBy
Aws Saad
• MS, is a long-lasting disease that can affect
brain, spinal cord, and the optic nerves in eyes. It
can cause problems with vision, balance, muscle
control, and other basic body functions.
• *In MS, the immune system attacks the protective
sheath (myelin) that covers nerve fibers and
causes communication problems between brain
and the rest of body. Eventually, the disease can
cause the nerves themselves to deteriorate or
become permanently damaged
Aws Saad
*Signs and symptoms of MS vary widely and
depend on the amount of nerve damage and
which nerves are affected
*Some people with severe MS may lose the
ability to walk independently or at all, while
others may experience long periods of
remission without any new symptoms.
Aws Saad
**The cause of multiple sclerosis is unknown.
It's considered an autoimmune disease in which
the body's immune system attacks its own
tissues.
*In the case of MS, this immune system
malfunction destroys myelin (the fatty
substance that coats and protects nerve fibers
in the brain and spinal cord).
Aws Saad
 Myelin can be compared to the insulation
coating on electrical wires. When the
protective myelin is damaged and nerve fiber
is exposed, the messages that travel along
that nerve may be slowed or blocked. The
nerve may also become damaged itself
Aws Saad
Multiple sclerosis signs and symptoms may
differ greatly from person to person and over
the course of the disease depending on the
location of affected nerve fibers. They may
include:
Aws Saad
1. Numbness or weakness in one or more limbs
that typically occurs on one side
2. Partial or complete loss of vision, usually in
one eye at a time, often with pain during eye
movement
3. Prolonged double vision
4. Tingling or pain in parts of body
5. Electric-shock sensations that occur with
certain neck movements, especially bending
the neck forward (Lhermitte sign)
Aws Saad
Lhermitte sign
Aws Saad
6.Tremor, lack of coordination or unsteady gait
7.Slurred speech
8.Fatigue
9.Dizziness
10.Problems with bowel and bladder function
Aws Saad
 Age
 Sex.
 Family history
 Certain infections: including Epstein-Barr, the
virus that causes infectious mononucleosis.
 Certain autoimmune diseases
Aws Saad
People with multiple sclerosis also may develop:
 Muscle stiffness or spasms
 Paralysis, typically in the legs
 Problems with bladder, bowel or sexual
function
 Mental changes, such as forgetfulness or
mood swings
 Depression
 Epilepsy
Aws Saad
 Blood tests, to help rule out other diseases
with symptoms similar to MS
 Lumbar puncture (spinal tap), in which a
small sample of fluid is removed from your
spinal canal for laboratory analysis. This
sample can show abnormalities in antibodies
that are associated with MS
Aws Saad
 MRI, which can reveal areas of MS (lesions) on
your brain and spinal cord
Aws Saad
 There is no cure for multiple sclerosis.
Treatment typically focuses on speeding
recovery from attacks, slowing the
progression of the disease and managing MS
symptoms. Some people have such mild
symptoms that no treatment is necessary.
 Corticosteroids : to reduce nerve
inflammation.
Aws Saad
 Plasma exchange (plasmapheresis). The liquid
portion of part of your blood (plasma) is
removed and separated from your blood cells
 Plasma exchange may be used if your
symptoms are new, severe and haven't
responded to steroids.
Aws Saad
Aws Saad

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Multiple sclerosis

  • 2. • MS, is a long-lasting disease that can affect brain, spinal cord, and the optic nerves in eyes. It can cause problems with vision, balance, muscle control, and other basic body functions. • *In MS, the immune system attacks the protective sheath (myelin) that covers nerve fibers and causes communication problems between brain and the rest of body. Eventually, the disease can cause the nerves themselves to deteriorate or become permanently damaged Aws Saad
  • 3. *Signs and symptoms of MS vary widely and depend on the amount of nerve damage and which nerves are affected *Some people with severe MS may lose the ability to walk independently or at all, while others may experience long periods of remission without any new symptoms. Aws Saad
  • 4. **The cause of multiple sclerosis is unknown. It's considered an autoimmune disease in which the body's immune system attacks its own tissues. *In the case of MS, this immune system malfunction destroys myelin (the fatty substance that coats and protects nerve fibers in the brain and spinal cord). Aws Saad
  • 5.  Myelin can be compared to the insulation coating on electrical wires. When the protective myelin is damaged and nerve fiber is exposed, the messages that travel along that nerve may be slowed or blocked. The nerve may also become damaged itself Aws Saad
  • 6. Multiple sclerosis signs and symptoms may differ greatly from person to person and over the course of the disease depending on the location of affected nerve fibers. They may include: Aws Saad
  • 7. 1. Numbness or weakness in one or more limbs that typically occurs on one side 2. Partial or complete loss of vision, usually in one eye at a time, often with pain during eye movement 3. Prolonged double vision 4. Tingling or pain in parts of body 5. Electric-shock sensations that occur with certain neck movements, especially bending the neck forward (Lhermitte sign) Aws Saad
  • 9. 6.Tremor, lack of coordination or unsteady gait 7.Slurred speech 8.Fatigue 9.Dizziness 10.Problems with bowel and bladder function Aws Saad
  • 10.  Age  Sex.  Family history  Certain infections: including Epstein-Barr, the virus that causes infectious mononucleosis.  Certain autoimmune diseases Aws Saad
  • 11. People with multiple sclerosis also may develop:  Muscle stiffness or spasms  Paralysis, typically in the legs  Problems with bladder, bowel or sexual function  Mental changes, such as forgetfulness or mood swings  Depression  Epilepsy Aws Saad
  • 12.  Blood tests, to help rule out other diseases with symptoms similar to MS  Lumbar puncture (spinal tap), in which a small sample of fluid is removed from your spinal canal for laboratory analysis. This sample can show abnormalities in antibodies that are associated with MS Aws Saad
  • 13.  MRI, which can reveal areas of MS (lesions) on your brain and spinal cord Aws Saad
  • 14.  There is no cure for multiple sclerosis. Treatment typically focuses on speeding recovery from attacks, slowing the progression of the disease and managing MS symptoms. Some people have such mild symptoms that no treatment is necessary.  Corticosteroids : to reduce nerve inflammation. Aws Saad
  • 15.  Plasma exchange (plasmapheresis). The liquid portion of part of your blood (plasma) is removed and separated from your blood cells  Plasma exchange may be used if your symptoms are new, severe and haven't responded to steroids. Aws Saad