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Multiple alleles
                                                   2

       ABO                     3         IA , IB       i)




 elearn.kjn.ac.th/elearn/web_ebook_rsbs/3_sipsang/genetic.pd

                                                                       f

                 ABO

             (      : blood type       blood group)


                                       (ABO System)
                 (Rh System)                                Antigen)


 1. ABO System                            A , B , AB          O
   (         O           ,A        B                          AB


 2. Rh System
1. +ve      Rh+ve            Rh (Rhesus) Antigen



2. -ve     Rh-ve               Rh (Rhesus) Antigen


                               0.03%



                          Rh-ve
                                  Rh+ve

                               A+ve            A Rh+ve
         AB-ve            AB                       Rh-ve
                           AB                        5%
   AB-ve            1.5

                                   Rh System
http://th.wikipedia.org



    1.                   4                               A B AB               O
                                                     ?
                                                A              B                  AB
     O
genotype                     IA _             IB _            I A IB              ii
                                       _i                 x            _i
genotype                               IA i               x            IB i
                                IA               i        x             IB         i
genotype                      IA I B             IA i                  IB I            ii
phenotype                    AB                      A                  B                   O
              A      B
     www.sahavicha.com
2.         ABO                                       IA IB    i



           IAi x IBIB
          genotype             IA i         x       IB IB
                               IA i                      IB
genotype                  IA I B                      IB i
       phenotype)       AB                            B4.2 IAIB x ii
          genotype             IA IB        x       ii
                         IA            IB       x        i
genotype                IA i                          IB i
       phenotype)       A                                B
 www.sahavicha.com


3.    2
                            A                                 O
                                            B                     AB


                                                     1x                A
                                                O
genotype                  (IA)_i x                      IA i
           O genotype                                                 ii
                                                                2x                      B
                                                                                AB
genotype                                                 IA_(i)        x         IB _
           AB genotype                                              IA I B
                   genotype                   IA i                                      A
      www.sahavicha.com




4.



     4.1                 O                                                                  AB


                               O         x                                 AB
     genotype            ii          x       IA IB
                               i                    IA         IB
            genotype          IA i           IB i
                               A                    B
4.2                                  AB                                               A
                                                                                         O


                                        AB                x                              O
    genotype                                             IA IB             ii
                                                         IA                     IB          i
                          genotype                                     IA i              I Bi
                                                          A                               B


        www.sahavicha.com


    5.                       4                                    A B AB             O



                    A                       IA i              IAIA
                    B                       IB i              IBIB
                    AB                           IA IB
                    O                       ii
                               IAi x IBi
                          IAIB IAi IBi ii
                                 IA i         IB i
         http://203.114.104.138
    6               ABO


A                                                             O
-                                       O


    P                  A                        A
               IAi XCY IAi XCXc



        IA X C         IAIAXCXC     IAIAXCXc        IAiXCXC   IAiXCXc
        IA Y           IAIAXCY      IAIAXcY         IAiXCY    IAiXcY
        iXC            IAiXCXC      IAiXCXc         iiXCY     iiXCY
        iY             IAiXCY       IAiXcY          iiXCY     iiXcY



                           A                                         O
                                  A                           IA i          i
                                                O
A                                                                        XC Y
                                        XC Xc
                                                                           A
                                                                           A
                                 3/16
        http://203.114.104.138
7.


-                      O                                           AB
         -               O                                AB
                       ii x IAIB
                             i I A IB
             IAi IBi
                   A;                   B
                                            O
                                                     AB
                                        A            B
                                                                   O
    -                              AB                          A
                                                 O
                             O                  AB
                       ii x IAIB
iIA IB
               IAi IBi
                    A                B
                                         A           IA IA
        IA i
        AB
        A

     http://203.114.104.138




8.                       ABO                 IA IB    i



        - IAi x IBIB
                          IA i I B
F1 1/2 IAIB 1/2 IBi
                                         AB : B           1:1
- IAIB x ii
                                    IA i I B i
                       F1 IAi IBi
                             A:B
                                         A:           B         1:1
        http://203.114.104.138




      9.

                  1.

                  2.

                  3.

                  4.                         disruptive

              1




                                                      A



        http://www.gotoknow.org
10.
                                       A       B
                      A       B


    1. 0%                     2. 25%               3.50%   4.
100%

          1

                             AB                    O
          A       B                        O

       http://www.gotoknow.org




    www.thaigoodview.com
    http://th.wikipedia.org
    www.sahavicha.com
    www.gotoknow.org
    http://203.114.104.138

elearn.kjn.ac.th/elearn/web_ebook_rsbs/3_sipsang/genetic.pdf



                                                           7-8
1.       5
2.   6
3.           19

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Multiple alleles กลุ่ม

  • 1. Multiple alleles 2 ABO 3 IA , IB i) elearn.kjn.ac.th/elearn/web_ebook_rsbs/3_sipsang/genetic.pd f ABO ( : blood type blood group) (ABO System) (Rh System) Antigen) 1. ABO System A , B , AB O ( O ,A B AB 2. Rh System
  • 2. 1. +ve Rh+ve Rh (Rhesus) Antigen 2. -ve Rh-ve Rh (Rhesus) Antigen 0.03% Rh-ve Rh+ve A+ve A Rh+ve AB-ve AB Rh-ve AB 5% AB-ve 1.5 Rh System
  • 3. http://th.wikipedia.org 1. 4 A B AB O ? A B AB O genotype IA _ IB _ I A IB ii _i x _i genotype IA i x IB i IA i x IB i genotype IA I B IA i IB I ii phenotype AB A B O A B www.sahavicha.com
  • 4. 2. ABO IA IB i IAi x IBIB genotype IA i x IB IB IA i IB genotype IA I B IB i phenotype) AB B4.2 IAIB x ii genotype IA IB x ii IA IB x i genotype IA i IB i phenotype) A B www.sahavicha.com 3. 2 A O B AB 1x A O
  • 5. genotype (IA)_i x IA i O genotype ii 2x B AB genotype IA_(i) x IB _ AB genotype IA I B genotype IA i A www.sahavicha.com 4. 4.1 O AB O x AB genotype ii x IA IB i IA IB genotype IA i IB i A B
  • 6. 4.2 AB A O AB x O genotype IA IB ii IA IB i genotype IA i I Bi A B www.sahavicha.com 5. 4 A B AB O A IA i IAIA B IB i IBIB AB IA IB O ii IAi x IBi IAIB IAi IBi ii IA i IB i http://203.114.104.138 6 ABO A O
  • 7. - O P A A IAi XCY IAi XCXc IA X C IAIAXCXC IAIAXCXc IAiXCXC IAiXCXc IA Y IAIAXCY IAIAXcY IAiXCY IAiXcY iXC IAiXCXC IAiXCXc iiXCY iiXCY iY IAiXCY IAiXcY iiXCY iiXcY A O A IA i i O A XC Y XC Xc A A 3/16 http://203.114.104.138
  • 8. 7. - O AB - O AB ii x IAIB i I A IB IAi IBi A; B O AB A B O - AB A O O AB ii x IAIB
  • 9. iIA IB IAi IBi A B A IA IA IA i AB A http://203.114.104.138 8. ABO IA IB i - IAi x IBIB IA i I B
  • 10. F1 1/2 IAIB 1/2 IBi AB : B 1:1 - IAIB x ii IA i I B i F1 IAi IBi A:B A: B 1:1 http://203.114.104.138 9. 1. 2. 3. 4. disruptive 1 A http://www.gotoknow.org
  • 11. 10. A B A B 1. 0% 2. 25% 3.50% 4. 100% 1 AB O A B O http://www.gotoknow.org www.thaigoodview.com http://th.wikipedia.org www.sahavicha.com www.gotoknow.org http://203.114.104.138 elearn.kjn.ac.th/elearn/web_ebook_rsbs/3_sipsang/genetic.pdf 7-8
  • 12. 1. 5 2. 6 3. 19