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1 of 19
(Multiple Allele)


                                  ABO
                                       single locus)
                        2          IA IB i


                                                 (Multiple
Allele)

                                        ABO
                                       single locus)
                        2          IA IB i

                                       F.
Bernstein)
                            ABO
                                   ABO

          16.3                                       ABO



                 IAIA IAi                    A
                 IBIB IBi                    B
IAIB                                AB
                ii                                 O

                                                ABO
                            3              IA IB        i
                        2            1
                multiple alleles)




Multiple alleles:
                            2                               ABO
                    3           IA , IB    i)




                                     ABO
IA =           A

     IB =           B

     i =            A       B

          IA   IB
                        A
B

     IAIA =                     A
A

     IBIB =                     A
B

     IAIB =                     A
AB

     ii    =            i


O
R1 =                      , R2 =
                     R1       R2




R1 R1 =              R2R2 =

R1R2 =      Roan (




          1:2:1
1.           complementary gene)


                                      2




                                           9:7

        2.                epistasis
)




melanin )    C


    c                                        cc
                                 B    b
                                                  B


                 b
2



               ABO           3
     IA IB i
                         2




                     1




1.             1
                                 1


2.
(Multiple Alleles)



                       ABO
                  (Single locus)             2
                IA IB        i           2       1




(Multiple Alleles)
           IA                        A
                  IB                     B
i                                 A           B
                        ABO



                     IA IB
      i                                  IA IB
                                            A        B


          A , B , AB         O




                  ABO
               ABO               4       A, B,
AB,       O(      null) 1.           A
(AA       AO) :
                                 A               B
2.         B (BB         BO):
                                 B               A
3.         AB :
A       B
           4.           O (OO) :


                        A     B
-                   A
(AO)                                   A         O            -
                A
(AA)                                   A                  -
                B
(BO)                                   B         O            -
                B
(BB)                                   B                 -
                AB                                           AB
       -
                O                                        A,       B,
    AB,         O       universal donors")       -
                A
(AO)                               A         O           -
                A
(AA)                               A                 -
                B
(BO)                               B         O           -
B
 (BB)                                        B             -
                          AB                               A,   B,
 AB,                 O         universal receivers") -
                          O                                O
                                ABO




             ABO                                 IA , IB   i



1. IAi   x       IB IB
         IA IB : IB i
  =1     :       1
                                    AB : B
  = 1 : 1
2. IAi       x       ii
         IAi : ii
  =1     :       1
                                   A:O
  = 1 : 1
ABO

     IA =                 A

     IB =                 B

     i =                  A       B

          IA   IB
                              A
B

     IAIA =                           A
A

     IBIB =                           A
B

     IAIB =                           A
AB

     ii    =                  i


O
R1 =                         , R2 =
                            R1       R2




      R1 R1 =               R2R2 =

      R1R2 =       Roan (               ––--–--––----–-




                1:2:1


                     Multiple alleles


                                                               2
     multiple alleles)         A           3             A1,
A2    A3                                    p, q     r
                p+q+r = 1
ABO




 2                              ABO
               3          IA    IB
        i                             IA= p ,
IB= q   i= r   p+q+r= 1
p+q+r)2
IA, IB, i
1.




                              F2




           L
           L'
genotype                LL              x       L'L'
                        L                        L'
genotype                                LL'
     F1 x F1            LL'             x        LL'
                L        L'                     L          L'
genotype F2     LL                LL'           LL'         L'L'
phenotype F2
                    1         :             2          :        1
2.                    4 -                     A B AB               O
                                                    ?


                              A                B                  AB
          O
genotype                     IA _             IB_             IAIB
     ii
                                        _i                x            _i
genotype                                IAi               x            IBi
                                   IA           i         x            IB
      i
genotype
                      IAIB   IAi                    IBI           ii
phenotype                     AB                    A                  B
          O
                  A      B


3.            2
                             A                                O
                                        B
AB
1x                          A
                                                    O
genotype                  (IA)_i x                 IAi
           O genotype               ii
                                   2x                           B
                                                   AB
genotype                  IA_(i)         x               I B_
           AB genotype             IAIB
                     genotype                IAi
                A


4.
     7.1incompletedominant




     7.2codominant




     7.3multiplealleles
single         locus)                                        2
                                                                                    ABO
                     IA I                                                           A B
              i                                                      A         B




 www.sahavicha.c&file=readknowledgeom/?name=know
ledge&id=
http://school.obec.go.th/njw/education/biology/chapter06/index_l06_p15.html

http://www.thaigoodview.com/library/contest2552/type2/science04/27/contents/genetics-
198a.html

http://www.biology.science.cmu.ac.th/lectures/202231/PopGen_MultiAllele.html

http://www.sahavicha.com/?name=test&file=readtest&id=481




1.                                                     10

2.                                                20

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มัลติเพิลส์

  • 1. (Multiple Allele) ABO single locus) 2 IA IB i (Multiple Allele) ABO single locus) 2 IA IB i F. Bernstein) ABO ABO 16.3 ABO IAIA IAi A IBIB IBi B
  • 2. IAIB AB ii O ABO 3 IA IB i 2 1 multiple alleles) Multiple alleles: 2 ABO 3 IA , IB i) ABO
  • 3. IA = A IB = B i = A B IA IB A B IAIA = A A IBIB = A B IAIB = A AB ii = i O
  • 4. R1 = , R2 = R1 R2 R1 R1 = R2R2 = R1R2 = Roan ( 1:2:1
  • 5. 1. complementary gene) 2 9:7 2. epistasis ) melanin ) C c cc B b B b
  • 6. 2 ABO 3 IA IB i 2 1 1. 1 1 2.
  • 7. (Multiple Alleles) ABO (Single locus) 2 IA IB i 2 1 (Multiple Alleles) IA A IB B
  • 8. i A B ABO IA IB i IA IB A B A , B , AB O ABO ABO 4 A, B, AB, O( null) 1. A (AA AO) : A B 2. B (BB BO): B A 3. AB :
  • 9. A B 4. O (OO) : A B - A (AO) A O - A (AA) A - B (BO) B O - B (BB) B - AB AB - O A, B, AB, O universal donors") - A (AO) A O - A (AA) A - B (BO) B O -
  • 10. B (BB) B - AB A, B, AB, O universal receivers") - O O ABO ABO IA , IB i 1. IAi x IB IB IA IB : IB i =1 : 1 AB : B = 1 : 1 2. IAi x ii IAi : ii =1 : 1 A:O = 1 : 1
  • 11. ABO IA = A IB = B i = A B IA IB A B IAIA = A A IBIB = A B IAIB = A AB ii = i O
  • 12. R1 = , R2 = R1 R2 R1 R1 = R2R2 = R1R2 = Roan ( ––--–--––----–- 1:2:1 Multiple alleles 2 multiple alleles) A 3 A1, A2 A3 p, q r p+q+r = 1
  • 13. ABO 2 ABO 3 IA IB i IA= p , IB= q i= r p+q+r= 1
  • 16. 1. F2 L L' genotype LL x L'L' L L' genotype LL' F1 x F1 LL' x LL' L L' L L' genotype F2 LL LL' LL' L'L' phenotype F2 1 : 2 : 1
  • 17. 2. 4 - A B AB O ? A B AB O genotype IA _ IB_ IAIB ii _i x _i genotype IAi x IBi IA i x IB i genotype IAIB IAi IBI ii phenotype AB A B O A B 3. 2 A O B AB
  • 18. 1x A O genotype (IA)_i x IAi O genotype ii 2x B AB genotype IA_(i) x I B_ AB genotype IAIB genotype IAi A 4. 7.1incompletedominant 7.2codominant 7.3multiplealleles
  • 19. single locus) 2 ABO IA I A B i A B www.sahavicha.c&file=readknowledgeom/?name=know ledge&id= http://school.obec.go.th/njw/education/biology/chapter06/index_l06_p15.html http://www.thaigoodview.com/library/contest2552/type2/science04/27/contents/genetics- 198a.html http://www.biology.science.cmu.ac.th/lectures/202231/PopGen_MultiAllele.html http://www.sahavicha.com/?name=test&file=readtest&id=481 1. 10 2. 20