Understanding Mental Health Apps — Neurotech SF presentationSteven Chan, MD MBA
What does the mental health app and psychiatry informatics landscape look like? A brief 15-minute look given at Neurotech SF conference at UCSF Mission Bay, by Steven Chan — University of California, Davis researcher and resident physician — on barriers, challenges, and near-term solutions on psychology, psychotherapeutics, and digital mental health.
Social media for tracking disease outbreaks–way of the future By.Dr.Mahboob a...Healthcare consultant
Traditional disease surveillance relies on data obtained from doctors, hospitals or laboratories through formal reporting systems. This yields valid and accurate data about emerging outbreaks and the impact of control strategies such as vaccinations. But it’s often not timely. Digital data are now publicly available from many sources. People talk about epidemics on social media using key words such as “fever” and “infection” before they are officially identified.
A surveillance system for detecting outbreaks of Ebola using Twitter, for example, could set geospatial tags for specific locations such as the African continent. It could search for a cluster of terms on the Twittersphere such as “haemorrhage”, “fever”, “virus”, “Ebola”, “Lassa” (an illness that can be confused with Ebola).
A system trying to identify influenza could mine terms that reflect visits to the doctor, purchase of tissues, paracetamol or aspirin from pharmacies, sick leave from work, as well as terms specific to the clinical syndrome of influenza.
Participatory design, the "Making" of Health and the Future of Diabetes Techn...Joyce Lee
We Hacked #DTM2014! A Joint Presentation by John Costik, Adrien de Croy, Weston Nordgren II, The Nightscout community, and Joyce Lee, MD, MPH, Doctor as Designer
mobile and #socialmedia - the cutting-edge #diabetes technology of the future...Joyce Lee
These slides are adapted from a talk that I gave in April at the 2014 Clinical Diabetes Technology Meeting in Los Angeles, about mobile technology and social media. I was honored to be presenting at the event. Thanks to Dr. Klonoff and the diabetes online community! Also, here was homework that I made for the site: http://joyceisplayingontheinter.net/andtalkingaboutdiabetestech.html
Understanding Mental Health Apps — Neurotech SF presentationSteven Chan, MD MBA
What does the mental health app and psychiatry informatics landscape look like? A brief 15-minute look given at Neurotech SF conference at UCSF Mission Bay, by Steven Chan — University of California, Davis researcher and resident physician — on barriers, challenges, and near-term solutions on psychology, psychotherapeutics, and digital mental health.
Social media for tracking disease outbreaks–way of the future By.Dr.Mahboob a...Healthcare consultant
Traditional disease surveillance relies on data obtained from doctors, hospitals or laboratories through formal reporting systems. This yields valid and accurate data about emerging outbreaks and the impact of control strategies such as vaccinations. But it’s often not timely. Digital data are now publicly available from many sources. People talk about epidemics on social media using key words such as “fever” and “infection” before they are officially identified.
A surveillance system for detecting outbreaks of Ebola using Twitter, for example, could set geospatial tags for specific locations such as the African continent. It could search for a cluster of terms on the Twittersphere such as “haemorrhage”, “fever”, “virus”, “Ebola”, “Lassa” (an illness that can be confused with Ebola).
A system trying to identify influenza could mine terms that reflect visits to the doctor, purchase of tissues, paracetamol or aspirin from pharmacies, sick leave from work, as well as terms specific to the clinical syndrome of influenza.
Participatory design, the "Making" of Health and the Future of Diabetes Techn...Joyce Lee
We Hacked #DTM2014! A Joint Presentation by John Costik, Adrien de Croy, Weston Nordgren II, The Nightscout community, and Joyce Lee, MD, MPH, Doctor as Designer
mobile and #socialmedia - the cutting-edge #diabetes technology of the future...Joyce Lee
These slides are adapted from a talk that I gave in April at the 2014 Clinical Diabetes Technology Meeting in Los Angeles, about mobile technology and social media. I was honored to be presenting at the event. Thanks to Dr. Klonoff and the diabetes online community! Also, here was homework that I made for the site: http://joyceisplayingontheinter.net/andtalkingaboutdiabetestech.html
Medical Doctor as Maker Designer: Participatory Design for HealthcareJoyce Lee
Slides from my Vanderbilt University Tech Talk on June 1, 2015. Video available here: http://mediasite.vanderbilt.edu/Mediasite/Play/36ef6c8ea30049d498201313ea925c711d
Gartner ranked Dell the #1 worldwide IT services provider in healthcare in 2014. Dell sees global disruptions in healthcare delivery and continues to invest in strategies to address these rapid changes. They are actively enhancing development, implementation and adoption of novel technologies, services, and applications that will revolutionize information-driven care, resulting in improved patient outcomes and overall cost savings worldwide. Dr. Nick is responsible for providing strategic insight and will discuss some Dell’s strategies to achieve an IT environment that is interconnected, efficient and patient-focused.
We live in a connected world where the effort required to communicate with someone has fallen causing the frequency and volume of communication to rise significantly. To effectively reach physicians it’s import to understand how they network and what platforms they use to stay connected. Learn more about physician networking by reviewing the infographic below: Physician Trends – Social Media.
DrBonnie360 brings the Lonely Voices of Autoimmune Disease back to Stanford MedicineX to Bridge the Autoimmune Abyss. Through Judy's story we explore the new discoveries that begin set the foundation.
Are you looking forward to top healthcare app ideas? Here's your guide! This article talks about innovative ideas in the medical field that will help revolutionize the healthcare industry.
2016: Why Now? An Overview of the TransTech Market and the Trends Driving Gro...Nichol Bradford
Watch the full talk here: https://www.youtube.com/watch?v=io8SGgSfHK8
Transformative Technology is at an inflection point. Understand the growth drivers, market leaders, and key cultural trends driving transformative technology, and learn how these affect you as entrepreneurs, investors, or users. Learn the most critical stats and trends about how technology is evolving. From the funding climate to smartphone adoption to the tech giants to cutting-edge inventions, this session has it all!
Nichol is the Co-Founder and Executive Director of the Transformative Technology Lab, Co-Organizer of the TTC, and the CEO and Founder of Willow, a TransTech company.
This presentation deck was used in the October 2019 PM360 webinar sponsored by QxMD.
Description:
Generating top-of-mind awareness is a key challenge in diagnosing both rare and non-rare diseases that otherwise could be missed. Creating that awareness is one of the biggest challenges for pharmaceutical marketers.
Join this webcast to explore the modern disease state awareness campaign and how innovative platforms can help you bring your information closer to the point of care, all from the perspective of a practicing clinician.
How can the Internet of Things (IoT) help us challenge the invisible epidemic of autoimmune disease?
Learn how healthcare is evolving in the age of connected devices, and how both recent and future innovations are improving patient experience & outcomes for those with chronic and autoimmune diseases.
Click through to view the slides from DrBonnie360's recent presentation at the Healthcare IoT Summit in San Francisco!
Wearable Health, Fitness Trackers, and the Quantified SelfSteven Tucker
The vision and reality of individualised health and wellness achieved through tracking personal data. An introduction to the scope of the problems followed by the advent of the Quantified Self. Then a pictorial view of trackers, gadgets, #ehealth, and #mHealth devices. This leads the audience to a clear understanding of how we can digitise behaviour and biology to achieve wellness and prevent disease in the 1st place. Overall, there is an underlying influence of the impact of exponential technologies in numerous fields with an increasing force in healthcare.
Are you in search of information related to brain health? Do you care for a person with a form of dementia like Alzheimer's, Lewy Body, Vascular, or Frontotemporal? Looking for a way to support someone caring for another with dementia?
Then please check out our Brain Health Bulletin! Please feel free to forward this to anyone who may find benefit in receiving it! The Brain Health Bulletin is designed to be your quick reference to the latest information about brain health, dementia research, technology, cultural awareness for effective, inclusive, and compassionate dementia treatment, care partner tools, and more!
Althe DiscussionMy proposed service for Bellevue Hospital Ment.docxrobert345678
Althe Discussion:
My proposed service for Bellevue Hospital “Mental health program that focuses on LGBTQIA+ Youth” (NYC Health + Hospitals, 2022,). This program would include counseling that will help them manage stress and depression, suicide prevention, substance abuse, homelessness and other services (Trevor Project, n.d). LGBTQIA+ youth may encounter some “negative health and life outcomes”, so it is crucial for them to have access to these and as many other services as possible (Centers for Disease Control and Prevention, 2020). The negative health and life outcomes LGBTQIA+ Youth experiences are issues with coming out to their friends and or family, social or fear rejection, they may experience violence, some form of trauma as well as inadequate mental or medical care (D’Amore Mental Health, n.d). By offering these services Bellevue Hospital can help with making a difference in the health and social disparities LGBTQIA+ youths face.
My focus on two of the five Ps of health care marketing.
For this program I will use two of the five P’s of healthcare marketing “physicians and patients” (Cellucci et al., 2014). The ones that will be utilizing these services are the patients. This program will focus on supporting the needs of these patients and assures them that they have all the support services available to them. The two of the Five Ps that I can apply my proposal is public and patients. The public health of the LGBTQIA+ Youth population would be affected the most from this proposed service. Such as homelessness, substance abuse and suicide can affect the community. Public health, “aims to improve the health and well-being of a group or a population”, not person (Cellucci et al., 2014).
References:
Cellucci, L. W., Wiggins, C., & Farnsworth, T. J. (2014).
Healthcare marketing: A case study approach. VitalSource Bookshelf version. vbk://9781567936056
Centers for Disease Control and Prevention, (2020, December).
LGBT youth resources.
https://www.cdc.gov/lgbthealth/youth-resources.htm
D’Amore Mental Health. (n.d).
Mental health issues in LGBTQ youth.https://damorementalhealth.com/mental-health-issues-in-lgbtq-youth/
Trevor Project, (n.d).
Mental health: You matter. Let’s keep you thriving. https://www.thetrevorproject.org/resources/page/2/?s=Mental%20Health
NYC Health + Hospitals, (2022, Octobe
r). Community health needs assessment 2022.https://hhinternet.blob.core.windows.net/uploads/2022/10/2022-CHNA-ISP-Report.pdf
Reply to Thread
Sharon Discussion
The proposed service chosen for Bellevue Hospital NYC’s Behavioral Health Department is transcranial magnetic stimulation (TMS). TMS is a treatment for depression for patients who do not respond to other medication and therapies. TMS is a “noninvasive procedure that uses magnetic fields to stimulate nerve cells in the brain to improve symptoms of depression.” (Mayo Clinic, 2018) The treatment inv.
The connection between physical and mental health, how health impacts personal and professional life, overcoming stigma, and small steps we can take to become a healthier tech industry.
Medical Doctor as Maker Designer: Participatory Design for HealthcareJoyce Lee
Slides from my Vanderbilt University Tech Talk on June 1, 2015. Video available here: http://mediasite.vanderbilt.edu/Mediasite/Play/36ef6c8ea30049d498201313ea925c711d
Gartner ranked Dell the #1 worldwide IT services provider in healthcare in 2014. Dell sees global disruptions in healthcare delivery and continues to invest in strategies to address these rapid changes. They are actively enhancing development, implementation and adoption of novel technologies, services, and applications that will revolutionize information-driven care, resulting in improved patient outcomes and overall cost savings worldwide. Dr. Nick is responsible for providing strategic insight and will discuss some Dell’s strategies to achieve an IT environment that is interconnected, efficient and patient-focused.
We live in a connected world where the effort required to communicate with someone has fallen causing the frequency and volume of communication to rise significantly. To effectively reach physicians it’s import to understand how they network and what platforms they use to stay connected. Learn more about physician networking by reviewing the infographic below: Physician Trends – Social Media.
DrBonnie360 brings the Lonely Voices of Autoimmune Disease back to Stanford MedicineX to Bridge the Autoimmune Abyss. Through Judy's story we explore the new discoveries that begin set the foundation.
Are you looking forward to top healthcare app ideas? Here's your guide! This article talks about innovative ideas in the medical field that will help revolutionize the healthcare industry.
2016: Why Now? An Overview of the TransTech Market and the Trends Driving Gro...Nichol Bradford
Watch the full talk here: https://www.youtube.com/watch?v=io8SGgSfHK8
Transformative Technology is at an inflection point. Understand the growth drivers, market leaders, and key cultural trends driving transformative technology, and learn how these affect you as entrepreneurs, investors, or users. Learn the most critical stats and trends about how technology is evolving. From the funding climate to smartphone adoption to the tech giants to cutting-edge inventions, this session has it all!
Nichol is the Co-Founder and Executive Director of the Transformative Technology Lab, Co-Organizer of the TTC, and the CEO and Founder of Willow, a TransTech company.
This presentation deck was used in the October 2019 PM360 webinar sponsored by QxMD.
Description:
Generating top-of-mind awareness is a key challenge in diagnosing both rare and non-rare diseases that otherwise could be missed. Creating that awareness is one of the biggest challenges for pharmaceutical marketers.
Join this webcast to explore the modern disease state awareness campaign and how innovative platforms can help you bring your information closer to the point of care, all from the perspective of a practicing clinician.
How can the Internet of Things (IoT) help us challenge the invisible epidemic of autoimmune disease?
Learn how healthcare is evolving in the age of connected devices, and how both recent and future innovations are improving patient experience & outcomes for those with chronic and autoimmune diseases.
Click through to view the slides from DrBonnie360's recent presentation at the Healthcare IoT Summit in San Francisco!
Wearable Health, Fitness Trackers, and the Quantified SelfSteven Tucker
The vision and reality of individualised health and wellness achieved through tracking personal data. An introduction to the scope of the problems followed by the advent of the Quantified Self. Then a pictorial view of trackers, gadgets, #ehealth, and #mHealth devices. This leads the audience to a clear understanding of how we can digitise behaviour and biology to achieve wellness and prevent disease in the 1st place. Overall, there is an underlying influence of the impact of exponential technologies in numerous fields with an increasing force in healthcare.
Are you in search of information related to brain health? Do you care for a person with a form of dementia like Alzheimer's, Lewy Body, Vascular, or Frontotemporal? Looking for a way to support someone caring for another with dementia?
Then please check out our Brain Health Bulletin! Please feel free to forward this to anyone who may find benefit in receiving it! The Brain Health Bulletin is designed to be your quick reference to the latest information about brain health, dementia research, technology, cultural awareness for effective, inclusive, and compassionate dementia treatment, care partner tools, and more!
Althe DiscussionMy proposed service for Bellevue Hospital Ment.docxrobert345678
Althe Discussion:
My proposed service for Bellevue Hospital “Mental health program that focuses on LGBTQIA+ Youth” (NYC Health + Hospitals, 2022,). This program would include counseling that will help them manage stress and depression, suicide prevention, substance abuse, homelessness and other services (Trevor Project, n.d). LGBTQIA+ youth may encounter some “negative health and life outcomes”, so it is crucial for them to have access to these and as many other services as possible (Centers for Disease Control and Prevention, 2020). The negative health and life outcomes LGBTQIA+ Youth experiences are issues with coming out to their friends and or family, social or fear rejection, they may experience violence, some form of trauma as well as inadequate mental or medical care (D’Amore Mental Health, n.d). By offering these services Bellevue Hospital can help with making a difference in the health and social disparities LGBTQIA+ youths face.
My focus on two of the five Ps of health care marketing.
For this program I will use two of the five P’s of healthcare marketing “physicians and patients” (Cellucci et al., 2014). The ones that will be utilizing these services are the patients. This program will focus on supporting the needs of these patients and assures them that they have all the support services available to them. The two of the Five Ps that I can apply my proposal is public and patients. The public health of the LGBTQIA+ Youth population would be affected the most from this proposed service. Such as homelessness, substance abuse and suicide can affect the community. Public health, “aims to improve the health and well-being of a group or a population”, not person (Cellucci et al., 2014).
References:
Cellucci, L. W., Wiggins, C., & Farnsworth, T. J. (2014).
Healthcare marketing: A case study approach. VitalSource Bookshelf version. vbk://9781567936056
Centers for Disease Control and Prevention, (2020, December).
LGBT youth resources.
https://www.cdc.gov/lgbthealth/youth-resources.htm
D’Amore Mental Health. (n.d).
Mental health issues in LGBTQ youth.https://damorementalhealth.com/mental-health-issues-in-lgbtq-youth/
Trevor Project, (n.d).
Mental health: You matter. Let’s keep you thriving. https://www.thetrevorproject.org/resources/page/2/?s=Mental%20Health
NYC Health + Hospitals, (2022, Octobe
r). Community health needs assessment 2022.https://hhinternet.blob.core.windows.net/uploads/2022/10/2022-CHNA-ISP-Report.pdf
Reply to Thread
Sharon Discussion
The proposed service chosen for Bellevue Hospital NYC’s Behavioral Health Department is transcranial magnetic stimulation (TMS). TMS is a treatment for depression for patients who do not respond to other medication and therapies. TMS is a “noninvasive procedure that uses magnetic fields to stimulate nerve cells in the brain to improve symptoms of depression.” (Mayo Clinic, 2018) The treatment inv.
The connection between physical and mental health, how health impacts personal and professional life, overcoming stigma, and small steps we can take to become a healthier tech industry.
IQYOU Health Crowdfunding oct 2016 10-14runstrong123
IQYOU Personalized Health Portal Croudfunding Opportunity. The first science-based heath portal to provide a blueprint for best health including your health risks and solutions to minimize risks and feel your best. Co-founded by Dr. Joseph Pizzorno, the father of evidence-based medicine, and founder of Bastyr University. Go to www.iqyouhealth.com and try it out for free!
Working in the tech industry often involves spending long hours sitting down, staring at a screen, consuming copious amounts of pizza and caffeine. The work is mentally demanding and can be stressful. In the rush to get everything done, it can be easy to neglect our health. But a healthy body and mind are necessary for effective performance. Based on HR training, research, and personal experience, this session provides realistic suggestions for managing your well-being at work. It covers the connection between physical and mental health, as well as how to discuss these topics with your employer. You’ll leave with a better idea of how to take care of yourself and be a happier, healthier, more productive person.
ABDOMINAL TRAUMA in pediatrics part one.drhasanrajab
Abdominal trauma in pediatrics refers to injuries or damage to the abdominal organs in children. It can occur due to various causes such as falls, motor vehicle accidents, sports-related injuries, and physical abuse. Children are more vulnerable to abdominal trauma due to their unique anatomical and physiological characteristics. Signs and symptoms include abdominal pain, tenderness, distension, vomiting, and signs of shock. Diagnosis involves physical examination, imaging studies, and laboratory tests. Management depends on the severity and may involve conservative treatment or surgical intervention. Prevention is crucial in reducing the incidence of abdominal trauma in children.
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Muktapishti is a traditional Ayurvedic preparation made from Shoditha Mukta (Purified Pearl), is believed to help regulate thyroid function and reduce symptoms of hyperthyroidism due to its cooling and balancing properties. Clinical evidence on its efficacy remains limited, necessitating further research to validate its therapeutic benefits.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
share - Lions, tigers, AI and health misinformation, oh my!.pptxTina Purnat
• Pitfalls and pivots needed to use AI effectively in public health
• Evidence-based strategies to address health misinformation effectively
• Building trust with communities online and offline
• Equipping health professionals to address questions, concerns and health misinformation
• Assessing risk and mitigating harm from adverse health narratives in communities, health workforce and health system
These lecture slides, by Dr Sidra Arshad, offer a quick overview of the physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar lead (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
6. Describe the flow of current around the heart during the cardiac cycle
7. Discuss the placement and polarity of the leads of electrocardiograph
8. Describe the normal electrocardiograms recorded from the limb leads and explain the physiological basis of the different records that are obtained
9. Define mean electrical vector (axis) of the heart and give the normal range
10. Define the mean QRS vector
11. Describe the axes of leads (hexagonal reference system)
12. Comprehend the vectorial analysis of the normal ECG
13. Determine the mean electrical axis of the ventricular QRS and appreciate the mean axis deviation
14. Explain the concepts of current of injury, J point, and their significance
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. Chapter 3, Cardiology Explained, https://www.ncbi.nlm.nih.gov/books/NBK2214/
7. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...Oleg Kshivets
Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Thyroid Gland- Gross Anatomy by Dr. Rabia Inam Gandapore.pptx
Mobile Mental Health Apps are Flooding the Marketplace: Who is using them and to what effect?
1. Mobile mental health apps are flooding the
marketplace:
Who is using them and to what effect?
Diego Castaneda DrPH MPH (UCSF)
Joaquin Anguera PhD (UCSF)
Patricia Arean PhD (UW)
diego.castaneda@ucsf.edu/
@drMhlth
2. Disclosures
• Research funded in part by NIH T32 mechanism
• No financial disclosures
diego.castaneda@ucsf.edu/
@drMhlth
4. What was the number of mobile
mental health apps on the market in
2014?
A. 5,000-10,000
B. 20,000-30,000
C. 30,000-40,000
D. What’s a mobile mental health app?
diego.castaneda@ucsf.edu/
@drMhlth
5. ANSWER
A. 5,000-10,000
D. What’s a mobile mental health app?
Patient Adoption of mHealth, Institute for Health Informatics, 2015
diego.castaneda@ucsf.edu/
@drMhlth
7. Research Context
• Last Year
• 100% Increase Health Apps
• ~165,000 Health Apps
• ~5,000 Mental Health Apps
• 1054 depression specific apps (Shen, 2015)
diego.castaneda@ucsf.edu/
@drMhlth
9. Research Questions
• What is a mental health app (real world def)?
• What mental health apps are actually being used?
• Who is using them?
• Are they engaged/satisfied with the app ?
• How long are the apps being used for (Longevity)?
• Usability
diego.castaneda@ucsf.edu/
@drMhlth
13. Findings-Demographics
N=1404
• Age M=35.2 (S.D. 11.7; Range 18-78)
diego.castaneda@ucsf.edu/
@drMhlth
Characteristic % of Sample
Female 70%
iPhone Device 50%
At least 4 years of college 49%
Download Apps (1 per day) 39%
18. What kind of health apps do
you have on your device?
diego.castaneda@ucsf.edu/
@drMhlth
Health App Category! % of Sample on Device!
Physical Health! 76%!
Diet Management!
!
61%!
Thinking/Cognitive Skills!
!
58%!
Mental Health! 34%!
!
Medication Adherence! 24%!
!
Chronic Disease! 18%!
!
19. What kind of health apps do
you have on your device?
diego.castaneda@ucsf.edu/
@drMhlth
Health App Category! % of Sample on Device!
Mental Health! 34% (483)!
!
20. Who is using mental health
apps (significantly)?
diego.castaneda@ucsf.edu/
@drMhlth
Characteristic! % of Sample! Mental Health App
on Device!
African-American*! 12%! 24%!
At least one Chronic Illness
(12 conditions)**!
48%! 60%!
Currently receiving mental
health care**!
24%! 34%!
App Downloader (At least
once per day)**!
39%! 44%!
Chi-Square test of Significance *p<.05, **p<.001
21. Top Ten Mental Health Apps!
1. WebMD!
2. Head Space!
3. Period Tracker!
4. Self-Anxiety Meditation !
5. T2MoodTracker!
6. Lumosity!
7. Stress Check!
8. MyFitness Pal!
9. Binaural Beats!
10. Relax Lite!
diego.castaneda@ucsf.edu/
@drMhlth
22. Top Ten Mental Health Apps!
1. WebMD!
2. Head Space!
3. Period Tracker!
4. Self-Anxiety Meditation !
5. T2MoodTracker!
6. Lumosity!
7. Stress Check!
8. MyFitness Pal!
9. Binaural Beats!
10. Relax Lite!
diego.castaneda@ucsf.edu/
@drMhlth
23. 16.1%
27.3%
56.6%
0
10
20
30
40
50
60
less than two weeks 2-4 weeks Over 4 weeks
For how long did you use the mental health app you said
you used? (% of mental health app users)
N=483
diego.castaneda@ucsf.edu/
@drMhlth
24. Usability Index
• 5 statements asking about overall usability of app
• Likert Scale- Strongly Disagree-Strongly Agree (0-10)
diego.castaneda@ucsf.edu/
@drMhlth
Statement! Score (SD)!
Easy to Learn to Use! 7.65 (2.6)!
Enter in Data Easily! 7.43 (2.6)!
Trusted App Confidentiality! 7.16 (2.7)!
Did What it was Supposed ! 7.39 (2.4)!
Functional on Phone! 7.40 (2.4)!
25. Open Ended Comments
What they Liked! What they Would Change !
Ease of use!
Tracking (Track) Data!
Access to Data!
Daily Tracking!
!
!
Nothing!!
Integrated with phone!
Costs (too expensive)!
Reminders!
!
!
diego.castaneda@ucsf.edu/
@drMhlth
26. Chronic Illness!
Under Care of Mental
Health Professional!
1. WebMD! WebMD!
2. Head Space! Self-Anxiety Meditation !
3. Self-Anxiety Meditation ! Head Space!
4. S-Health! T2 Mood Tracker!
5. GoogleFit! Binaural Beats!
6. MyFitness Pal! Calm!
7. Period Tracker! Depression!
8. Relax Lite ! Lumosity!
9. T2 Mood Tracker! MoodScope!
10. Binaural Beats! Period Tracker!
diego.castaneda@ucsf.edu/
@drMhlth
27. Chronic Illness!
Under Care of Mental
Health Professional!
1. WebMD! WebMD!
2. Head Space! Self-Anxiety Meditation !
3. Self-Anxiety Meditation ! Head Space!
4. S-Health! T2 Mood Tracker!
5. GoogleFit! Binaural Beats!
6. MyFitness Pal! Calm!
7. Period Tracker! Depression!
8. Relax Lite ! Lumosity!
9. T2 Mood Tracker! MoodScope!
10. Binaural Beats! Period Tracker!
diego.castaneda@ucsf.edu/
@drMhlth
28. Summary
• Representative Race/Income
• Minority use similar
• Unconventional Mental Health Definitions
• Specific Populations
• Engagement (Longevity) and User Satisfaction
diego.castaneda@ucsf.edu/
@drMhlth
29. Implications for Clinicians
• Patient/client interest (augment treatments)?
• Special population?
• Chronic illness
• Smartphone + data plan (tech-phillic)
• Take time to identify several apps to recommend
• Delegate an app search for 1-2 top apps
• Users are looking for
• Ease of Use
• Integration
diego.castaneda@ucsf.edu/
@drMhlth
30. Implications Greater Context
• Precision Medicine Initiative
• Active Partners
diego.castaneda@ucsf.edu/
@drMhlth
PMI Working Group, 9/17/2015
http://www.nih.gov/precisionmedicine/09172015-pmi-working-group-report.pdf
31. “The Future is Already Here..It’s just not very well
distributed.”
-William Gibson
diego.castaneda@ucsf.edu/
@drMhlth
32. Acknowledgements
• Grace Niu PhD
• Rebecca Willemse BS
• Katrina Roundfield PhD
• Pat Arean PhD
• Joaquin Anguera PhD
• Amy Byers PhD
• Adrian Aguilera PhD
• Cami Rolle BS
• Josh Jordan MS
• Claudine Catledge MS
• Rachel Lewin RN
diego.castaneda@ucsf.edu/
@drMhlth