To adjust the brightness and contrast of an image using Microsoft Picture Manager: 1. Right click the image file and select "Open with" then "Microsoft Picture Manager". 2. Click "Edit Images" to display the editing tools. 3. Select "Bright and Contrast" to open the brightness and contrast sliders. 4. Move the brightness and contrast sliders left and right to lighten, darken, or increase/decrease contrast and observe the changes to the image.