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DARSHANA ARADHYE
Mobile: +91-9099910969 / 0869078757 ~ E-Mail: darshanaaradhye@yahoo.com
Dear Sir/ Madam,
Please find attached my Resume for the position of equivalent job . I'm particularly interested in this position, which relates strongly to my over 11 years of experience in teaching ,administration ,curriculum framing, staff management
Currently working with Global India International as academic co ordinator for primary
Worked also as Head mistress with Pinnacle public school, Gandhinagar., Gujarat , I believe I meet all the essential criteria of the position. Few of my highlights of experience and demonstrated talent I would bring to your organisation include:
(a) Curriculum framing and setting up systems like lesson plan, time table, H.W. time table
(b) Review of team members
(c) Submission of MIS documents
(d) Guiding teachers for activity based teaching
(e) Organizing various events like –Sport’s day, Grandparents ‘s day, father ‘s day out ,convocation,CCE activities ,Annual functions and many other activities carried out in the school
(f) Leading team of 46 teacher, supervised 400 hundred children and support staff
I am now looking to take up roles as a vice principal /equivalent in a well known organisation. Of particular interest to me would be in this position.
I appreciate your taking the time to review my credentials and experience. Looking forward to a positive response.
Thanking you.
Sincerely,
Darshana Aradhye
Enclosure: Resume
DARSHANA ARADHYE
Mobile: +91-9099910969 / 0869078757 ~ E-Mail: darshanaaradhye@yahoo.com
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Nous verrons comment générer un fichier hprof afin d'analyser l'empreinte mémoire d'une application dans l'outil dédié MAT (Eclipse Memory Analyzer) et mettre en avant la présence ou non de fuite mémoire.
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Fexofenadine is sold under the brand name Allegra.
It is a selective peripheral H1 blocker. It is classified as a second-generation antihistamine because it is less able to pass the blood–brain barrier and causes lesser sedation, as compared to first-generation antihistamines.
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Receptor Discordance in Breast Carcinoma During the Course of Life
Definition:
Receptor discordance refers to changes in the status of hormone receptors (estrogen receptor ERα, progesterone receptor PgR, and HER2) in breast cancer tumors over time or between primary and metastatic sites.
Causes:
Tumor Evolution:
Genetic and epigenetic changes during tumor progression can lead to alterations in receptor status.
Treatment Effects:
Therapies, especially endocrine and targeted therapies, can selectively pressure tumor cells, causing shifts in receptor expression.
Heterogeneity:
Inherent heterogeneity within the tumor can result in subpopulations of cells with different receptor statuses.
Impact on Treatment:
Therapeutic Resistance:
Loss of ERα or PgR can lead to resistance to endocrine therapies.
HER2 discordance affects the efficacy of HER2-targeted treatments.
Treatment Adjustment:
Regular reassessment of receptor status may be necessary to adjust treatment strategies appropriately.
Clinical Implications:
Prognosis:
Receptor discordance is often associated with a poorer prognosis.
Biopsies:
Obtaining biopsies from metastatic sites is crucial for accurate receptor status assessment and effective treatment planning.
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Skin is the largest organ of the human body, serving crucial functions that include protection, sensation, regulation, and synthesis. Structurally, it consists of three main layers: the epidermis, dermis, and hypodermis (subcutaneous layer).
1. **Epidermis**: The outermost layer primarily composed of epithelial cells called keratinocytes. It provides a protective barrier against environmental factors, pathogens, and UV radiation.
2. **Dermis**: Located beneath the epidermis, the dermis contains connective tissue, blood vessels, hair follicles, and sweat glands. It plays a vital role in supporting and nourishing the epidermis, regulating body temperature, and housing sensory receptors for touch, pressure, temperature, and pain.
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