The customer needed a new single-use tangential flow filtration (TFF) system for their clinical production facility as their current system was yielding inconsistent results during ultrafiltration processes. To address this challenge and win the customer's confidence, the team created a mock-up of their custom single-use TFF mix bag and recirculation flow path in the M Lab Collaboration Center. Seeing the mock-up firsthand helped gain the customer's trust, and they adopted the custom single-use TFF bag for their new single-use TFF implementation.

1. The customer gained confidence after seeing
the mock-up first-hand in the M Lab™
Collaboration Center and adopted our custom
single-use TFF mix bag (mix 50 scale) for their
single-use TFF implementation.
Outcome
To win the customer’s confidence in our
TFF bags, the team in North America
mocked up the single-use TFF mix bag and
recirculation flow path to characterize
mixing their UF1 and UF2 processes using
a dye/salt solution.
Solution
The customer needed a new single-use TFF
system for their clinical production facility,
as their current system was yielding a
range of concentration/viscosity/volume
during UF processes.
Customer
Challenge
TFF System
Implementation
#MLabCollaboration
Collaborate with us to solve
your TFF challenges.
MerckMillipore.com/MLabs
M Lab™ Collaboration Center
Success Story
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