20. The normal prostate
contains several distinct
regions, including a
central zone (CZ), a
peripheral zone (PZ), a
transitional zone (TZ),
and a periurethral zone.
Most carcinomas arise
from the peripheral
glands of the organ and
may be palpable during
digital examination of the
rectum.
Nodular hyperplasia, in
contrast, arises from
more centrally situated
glands and is more likely
to produce urinary
obstruction early than is
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