1) A 16-year old female presented with a 3 month history of oral ulcers. Examination also revealed a butterfly rash on her face and a history of joint pain.
2) Based on these findings along with laboratory tests, she was diagnosed with systemic lupus erythematosus (SLE). Oral ulcers can be an early sign of SLE.
3) Treatment with steroids and immunosuppressants led to improvement of her oral and skin lesions. This case highlights the importance of thorough medical history and examination of extra-oral sites in accurately diagnosing systemic conditions that present with oral manifestations.