The document discusses the integration of basic sciences with clinical practices in the context of patient diagnosis and management. It emphasizes the importance of understanding anatomy, physiology, pathology, and biochemistry for effective communication and treatment in clinical settings. The speaker, a consultant surgeon, highlights examples like trauma and aortic aneurysms to demonstrate the application of basic sciences in real clinical scenarios.

1. Linking
Clinical
to
Basic sciences
Joel Arudchelvam
Consultant Vascular and Transplant Surgeon, National Hospital of Sri Lanka.
Senior lecturer, Department of Surgery, faculty of medicine, University of
Colombo.

2. Patient presentation
Patient
presentati
on
Diagnosis
Manage
and
discharge

3. Integration of basic sciences -
why
 Student learn the relevance
 Understanding and retention of knowledge
 Stimulates interest
 Also improves the communication and integration
into the clinical team

4. The disease
Causes
Pathophysiolo
gy
Pathology
Anatomy
Biochemical
changes
Physiological
changes
Clinical
features

5. Diagnosi
s
Investigatio
ns
Management
options /
management

6. Basic sciences
Anatomy
Physiology
Pathology
Biochemistry

7. Diagnosis
Anatomy
Pathology
Aetiology
Complications / stage
Disability

8. Clinical – How to apply
 Trauma
 Varicose veins – Surgery
 Aortic aneurysms

9. Examination
• Aortic – above
umbilicus
• Aorto – iliac -
below umbilicus
• Can / cannot feel
upper margin -
suprarenal

10. What is injured

11. Physiology
Aortic clamping
De clamping
Reperfusion cellular
mechanisms

12. Pathology
 E.g : renal cell
carcinoma – basis for
the clinical
presentation

13. Biochemistry
 Biochemical tests e.g
liver function tests

14. Conclusions
 Understanding and applying the basic scientific
basis of the patient presentation and
management is important