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Gawad
Neuroscience Physiology
Lecture 4
Friday, November 2, 2018 1
Properties of receptors
1. Differential Sensitivity (Specificity) (Muller's law):
Friday, November 2, 2018 2
Receptor adequate stimulus
+specific projection
modality of sensation
Each receptor is giving rise to one type of sensation,
regardless the method of stimulation, how?
Properties of receptors
1. Differential Sensitivity (Specificity) (Muller's law):
Friday, November 2, 2018 3Receptor
adequate stimulus
(light)
+
specific projection
modality of sensation
(image)
Properties of receptors
1. Differential Sensitivity (Specificity) (Muller's law):
Friday, November 2, 2018 4Receptor
specific projection
modality of sensation
(image)
Properties of receptors
(2) Excitability (receptor potential):
Friday, November 2, 2018 5
Receptor
+ + + + + + + + + + + + + + + +
- - - - - - - - - - - - - - - - - - - - - -
adequate stimulus
+
receptor or generator
potential
action potential
Na
Na
Na
Na
Na
Na
Na
Na
Na
Na
Na
Na
Na
Na
Na
Na
Na
Na
Na
Na
Na
Na
Na
NaNa
Stimulus
strength
Receptor
potential
-70
-60
Afferent
potential
-70
Na
Na
Na
Stimulus
strength
Receptor
potential
-70
-60
Afferent
potential
-70
NaNa
Na
Na Na
Stimulus
strength
Receptor
potential
-70
-60
Afferent
potential
-70
NaNa
Na Na
NaNa
NaNa
NaNa
NaNa
Stimulus
strength
Receptor
potential
-70
-60
Afferent
potential
-70
NaNa
Na Na
NaNa
Na
Na
Na
NaNa
Na Na
NaNa
Stimulus
strength
Receptor
potential
-70
-60
Afferent
potential
-70
Na
Na
NaNa
Na
Na
NaNa
NaNa
NaNa
Stimulus
strength
Receptor
potential
-70
-60
Afferent
potential
-70
Na
Na
NaNa
Na
Na
Na
Na
Na
Na
Na
Na
Stimulus
strength
Receptor
potential
-70
-60
Afferent
potential
-70
Na
Na
NaNa
Na
Na
Na
Na
Na
Na
Na
Na
Stimulus
strength
Receptor
potential
-70
-60
Afferent
potential
-70
Na
Na
NaNa
Na
Na
Na
Na
Na
Na
Na
Na
Stimulus
strength
Receptor
potential
-70
-60
Afferent
potential
-70
Na
Na
NaNa
Na
Na
Na
Na
Na
Na
Na
Na
Properties of receptors
(3) Adaptation:
Friday, November 2, 2018 20
Properties of receptors
(3) Adaptation:
Friday, November 2, 2018 21
Stimulus
strength
Receptor
potential
-70
-60
Afferent
potential
-70
Na
Na
NaNa
Na
Na
Na
Na
Na
Na
Na
Na
Friday, November 2, 2018 23
Friday, November 2, 2018 24
Receptor adequate stimulus
+
Friday, November 2, 2018 25
Receptor
Friday, November 2, 2018 26
Receptor
specific projection
modality of sensation
Friday, November 2, 2018 27
Receptor
specific projection
modality of sensation
Friday, November 2, 2018 28
Stimulus
strength
Receptor
potential
-70
-60
Afferent
potential
-70
Na
Na
NaNa
Na
Na
Na
Na
Na
Na
Na
Na
Stimulus
strength
Receptor
potential
-70
-60
Afferent
potential
-70
Na
Na
NaNa
Na
Na
Na
Na
Na
Na
Na
Na
Stimulus
strength
Receptor
potential
-70
-60
Afferent
potential
-70
Na
Na
NaNa
Na
Na
Na
Na
Na
Na
Na
Na
Friday, November 2, 2018 32

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Lecture+4