Controlled release iodine dressings were found to significantly improve wound healing outcomes compared to silver dressings. There was significant evidence that controlled release iodine dressings supported greater complete healing by weeks 4-6 when used with compression therapy, and also showed faster healing rates even without compression therapy. Controlled release iodine also demonstrated significantly lower treatment costs than other dressings. IodoFoam is the only controlled release iodine dressing that has full Medicare reimbursement.